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1 ly and effectively cross biological barriers and thereby access and photosensitize retinal neurons.
2 ient removal of H2 antigen from erythrocytes and thereby accomplishes the conversion of regular human
4 , and gene drive disrupting a fertility gene and thereby achieving population suppression or collapse
6 cell swelling induced by osmotic challenges and thereby activated TRPV4-mediated transmembrane curre
9 ehavioral drive (i.e., motivation) to burrow and thereby affect both the developmental timing and adu
10 logical events that affect influential nodes and thereby affect information flow could have a strong
11 ly controls the chloroplast reductive status and, thereby, affects isoprene emission, but they do not
12 persistent polymers in numerous applications and thereby alleviate plastic accumulation in the enviro
13 lineages in the newly apomictic population, and thereby alleviates some of the usual pitfalls of ase
14 are methylated, MBD proteins can block them and thereby allow Egr-1 to avoid sequestration in non-fu
15 le-stranded RNA (dsRNA)-activated kinase PKR and thereby allowed virus-induced increases in the abund
17 riptome that regulate RNA-HNRNPG interaction and thereby alter the expression and alternative splicin
19 the electrocatalytic reduction of CO2 to CO, and thereby altering the electrocatalytic mechanism at t
20 es a cognitive map of expected reward in OFC and thereby alters general value signals in vmPFC to gui
21 1 directs Abeta into off-pathway structures, and thereby alters various solution based functions of A
23 , solid evidence indicates that ureagenesis, and thereby amino acid levels, is critically controlled
24 the oxidation overpotential of test analyte and thereby amplifying electronic transmission, without
25 ng to reduced expression of MDR transporters and thereby an increased accumulation of sorafenib in th
26 phy-induced phosphorylation of PIF3 in vivo, and thereby are critical components of a transcriptional
27 ed NPs may penetrate skin to a lesser extent and thereby are less able interact with and alter the lo
28 mer jointly bind to an ssDNA/dsDNA substrate and, thereby, at least partially dictate the incision po
29 selectively modulates tissue characteristics and thereby attenuates immune cell attraction and activa
32 at SIRT3 deficiency occurs in fibrotic lungs and thereby augments AEC mtDNA damage and apoptosis.
34 interactions with more than two participants and thereby avoids the need to first expand these into m
36 ic role in influencing nTS neuronal activity and thereby basal and reflex cardiorespiratory function
37 that inhibit nuclear export of the receptor and thereby block TGF-beta-induced migration and EMT.
38 kappaBalpha for substrate binding to IKKbeta and thereby blocks IkappaBalpha phosphorylation and NF-k
39 subunit of interleukin-23 and interleukin-12 and thereby blocks the activity of these cytokines, inhi
40 0 microm), much smaller aspect ratios (<0.2) and thereby, can be fabricated in a single lithography s
44 nfluence host-mediated effects on ecosystems and, thereby, change the likelihood and strength of eco-
47 nce can result in a biphasic growth behavior and thereby confer the 'adapted' bacterial cells an enha
48 e human promyelocytic leukemia (HL-60) cells and thereby confirm q-DC measurements of Ea = 0.53 +/- 0
50 been offered genetic counseling and testing and thereby contribute to a reduction in health disparit
51 oteins mediate gene regulation by small RNAs and thereby contribute to cellular homeostasis during di
52 s that target its deep vs superficial layers and thereby contribute to the behavioral consequences of
53 requirements of next-generation antibodies, and thereby contribute to the design of broadly protecti
54 tDNA could be altering epigenetic regulation and thereby contribute to the pathogenesis of metastasis
55 alization of Prxs into distinct compartments and thereby contribute to various mitochondrial redox pr
56 productivity, exacerbated the host response, and thereby contributed to the high pathogenicity of H5N
57 porations in enabling transformative change, and thereby contributes to advancing the limited underst
58 attenuates p27's inhibitory activity on CDK2 and thereby contributes to increased G1-S phase transiti
59 h TORC1 signaling controls Stu2 localization and thereby contributes to proper MT cytoskeletal organi
60 gen enhances IL-4-induced M2 gene expression and thereby contributes to sex differences observed in a
61 loops or networks to fine-tune transcription and thereby control diverse biological processes such as
62 espectively, fine tune levels of SHH and IHH and, thereby control the transit of proliferating immatu
63 igase complex, targets DMRT1 for degradation and thereby controls the mitosis-meiosis transition in m
65 rces, which influence intracellular dynamics and thereby create unique biophysical signatures, which
66 te mitogen-activated protein kinases (MAPKs) and thereby critically modulate cell proliferation and d
67 xpansion of antigen-stimulated T and B cells and thereby curtails adaptive immune responses in vivo.
69 ought to increase maintenance energy demands and thereby decrease available resources for yield forma
70 treatment selectively reduced the dwell time and thereby decreased the confinement of GABAARs at inhi
72 ent exocytosis of AMPA receptors during LTP, and thereby delineate a simple mechanism for the recruit
73 itivities, and good detonation performances, and thereby demonstrate the potential applications as ne
74 uppresses BMI1-induced ubiquitylation of H2A and thereby derepresses homeobox HOXC5 and HOXC13 gene e
75 latform to understand this adaptive response and thereby design rational combinatorial approaches.
76 ses structural perturbation in the A2 domain and thereby destabilizes the domain by approximately 10
77 with Cdc20 (APC/C(Cdc20)) activates separase and thereby destroys cohesion along chromosome arms.
78 rmediate and deep layers of the SCm and SCl, and thereby determined the main input structures to thes
79 rocess that shapes goal-directed evaluations and thereby determines the outcome of high-level sequent
83 mo-7-nitroindazole, competes for ATP binding and thereby diminishes FADH degrees formation, which dem
84 icle diameter impacts the NV center lifetime and thereby directly impacts the accessible contrast and
85 through covalent chemical functionalization, and thereby directly influence the kinetics of the hydro
86 ructure over the duration of the experiment, and thereby discover trial-to-trial variability in the s
88 iR-204, directly targets the 3' UTR of GLP1R and thereby downregulates its expression in the beta-cel
89 tional allosteric site 40 A away from loop 2 and thereby drive formation of activated or inactive hex
91 ll sorting (FACS) and single-cell deposition and thereby eliminates the above-mentioned problems.
92 icle shape (cubic, spherical, or tetrapodal) and, thereby, emission properties can be synthetically t
93 of the tetravalent dengue vaccine, CYD-TDV, and thereby enabled virus genotype-specific estimates of
95 regase Hsp104 helps to dissociate aggregates and thereby enables refolding or degradation of misfolde
96 niversal methods to reset all other contexts and thereby enhance all other efforts to promote the rig
100 ation and cytokine production of macrophages and thereby enhanced migration of VEGFR1(+) myeloid cell
101 ocaine exposure decreases G9a in this region and thereby enhances expression of certain addiction-pro
102 s FIN219 to switch to its high-affinity mode and thereby enhances JA signaling under continuous FR li
103 )) had a minor impact reducing digestibility and thereby enhancing antigenicity of unheated beta-lg a
104 lower recruitment synchrony between species and thereby enhancing niche partitioning through the sto
105 nt still will have suffered cytotoxic stress and thereby enter a stem cell-like state, the seeds for
106 loride concentration found in mature neurons and thereby establishes the driving force for the chlori
109 ts to sensitize central nociceptive networks and thereby evoke persistent pain in children following
110 icting its capability to promote cell growth and thereby exaggerating hyperoxia-induced lung epitheli
111 ellular level to large-scale neural systems, and thereby explain shifts in cognitive functioning duri
112 ession of PNPLA3 during human HSC activation and thereby explored how a PNPLA3 variant impacts hepati
114 acetylated lysine residues on histone tails and thereby facilitate the reading of the histone code.
115 pithelium remodeling in the posterior midgut and thereby facilitates the trans-epithelial migration o
117 limit the evolution boundary layer processes and thereby failed to simulate convection at right time
119 f a gel that could be filled with a solvent, and thereby form a mechanically stable gel-like material
121 stream of cancer-relevant signaling pathways and thereby function as a nexus between signaling and ea
122 ught to contain neurons that trigger voiding and thereby function as the "pontine micturition center.
124 t population abundance by displacing animals and thereby functionally reducing the amount of availabl
125 1 using both specific and random mutagenesis and thereby generate mutations in all open reading frame
127 down" ecological processes and interactions, and thereby generating new scaling relationships for eco
128 rivaroxaban plus DAPT could reduce bleeding and thereby have a favorable impact on all-cause mortali
129 130 leads to the degradation of cellular RNA and thereby heat-induced programmed cell death that in t
130 pectrum disorder may clarify pathomechanisms and thereby help identify targets for drug intervention
131 lection, self-organization, and development) and thereby help integrate knowledge stemming from diver
132 underpin a number of neurological disorders and thereby highlight the importance of understanding th
133 rpretation of epilepsy disease-risk variants and, thereby, highlight novel potential causal genes for
135 protein functioning as a molecular scaffold and thereby hosting interactions with several protein pa
138 tor protein for Toll-like receptor 4 (TLR4), and thereby impact both virus replication and cellular i
139 oral mismatches between interacting species, and thereby impact population and community dynamics.
140 ce can reverse these chromatin modifications and thereby impact the expression of key metabolic genes
141 critical interactions in the binding of ATP and thereby impair ATP-induced nucleotide-binding domain
142 PD-1 was recently shown to be expressed on and thereby impair the functions of tumor-infiltrating m
143 ity and localization within the marrow space and thereby impairs proper lodgment into the niche.
144 the soil rhizosphere, chelating Al(3+) ions and thereby imparting Al-resistance based on excluding A
145 ypes, indicating differences in age at onset and thereby implying differences in the underlying etiol
146 NHEJ relies on Ku to thread onto DNA termini and thereby improve the affinity of the NHEJ enzymatic c
147 rt at nanometre and mesoscopic length scales and thereby improve the thermoelectric performance of th
151 hat they alter the planar membrane structure and thereby increase the activation energy required for
152 e pro-angiogenic and pro-tumorigenic factors and thereby increase tumor growth, the precise molecular
154 time, a prolonged reproductive growth phase, and, thereby, increased seed yield suggest that cytokini
157 o activate PKR by enhancing binding affinity and thereby increasing the population of productive comp
158 een used to disturb cellular ion homeostasis and thereby induce cell death; however, it is not clear
159 vates cyclic nucleotide-gated (CNG) channels and thereby induces a Ca(2+) influx, which leads to the
160 to identify genetic variants that affect EE and thereby influence BMI and body fatness in Pima India
162 t contributes to VSD-pore coupling via PIP2, and thereby influences the unique gating effects of reti
165 apoptosis signal-regulating kinase 1 (ASK1) and thereby inhibited the MPP(+)-induced stimulation of
166 of capsule polysaccharide in shielding OmpA and thereby inhibiting anti-OmpA MAb binding to clinical
167 ity of the associated Beclin 1-Vps34 complex and thereby inhibiting phosphoinositide production.
169 vity such that the protein degrades c-di-GMP and thereby inhibits matrix production during oxidizing
171 ores absorb light in photosensitive proteins and thereby initiate fundamental biological processes su
173 profoundly affects the properties of pectin and, thereby, is critical for plant development and the
174 by improving the identification of entities and thereby leading to potential new therapeutic avenues
176 hat the Braun's lipoprotein tilts and bends, and thereby lifts the cell wall closer to the outer memb
177 ities into the follicular mature compartment and thereby likely increasing the risk for seeding of au
178 pression inhibits IL-5 production by T cells and thereby limits natural Ab production by B-1 cells.
179 esults in random expression of these factors and, thereby, lineage scrambling that is disconnected fr
181 phage M2 polarization or cholesterol efflux, and thereby MafB mediates their beneficial effects, in b
184 (-) concentration following cAMP stimulation and thereby maximizing the secreted HCO3(-) concentratio
186 ough deforestation, agriculture, and burning and thereby might reduce the capacity of landscapes to p
187 s and post-translational modifications (PTM) and thereby minimize the risk of being clinically meanin
188 spread T-cell epitopes in any biotherapeutic and thereby mitigate this key source of detrimental immu
189 ed increase in endothelial monolayer tension and thereby moderate inflammation-induced junction loss
190 in cytokine genes can affect gene expression and thereby modulate inflammation and carcinogenesis.
191 ), effectively becoming sponge for miR-26a/b and thereby modulating the expression of transforming gr
193 n initiation and regulate pre-mRNA splicing, and thereby mRNA isoform production, by (i) influencing
194 short-circuit current density, fill factor, and thereby much higher power conversion efficiency (PCE
195 cally in individuals and within populations, and thereby multiply their overall disease burden, and t
197 rimary cell wall cellulose synthase complex, and thereby negatively regulate cellulose biosynthesis.
198 capable of emitting from two excited states and thereby of producing two photoluminescence colours a
199 tion of tyrosine hydroxylase phosphorylation and, thereby, of dopamine synthesis, supporting a major
200 pact of methylome changes on gene expression and thereby on the function of the tissue, including est
201 icularly noteworthy because the composition, and thereby organization, of RSCs in yeast and human is
202 with LHP1-PRC2 complexes during replication and thereby participates in maintaining the H3K27me3 mar
203 nslation of abundant iron-utilizing proteins and thereby permit the most essential iron-dependent enz
205 gulating the stem cell niche in many organs, and thereby pivotally modulates development, homeostasis
206 epresses transposable elements in the gonads and thereby plays a vital role in protecting the integri
211 ic targets for attenuating this inflammation and thereby preventing CKD-associated cardiovascular dis
212 ing photochemical damage to the NER proteome and thereby preventing the removal of UVB-induced DNA le
213 cient RPA2S4-S8 and CHK1S345 phosphorylation and thereby prevents cellular senescence, IPF and carcin
214 ed neutrotrophic factor (MANF) in beta-cells and thereby prevents the BH3-only protein BIM (BCL2-inte
215 nduces DR5 clustering at the plasma membrane and thereby primes tumor cells to caspase-mediated apopt
217 ons further destabilize labile E-S complexes and thereby promote generation of longer Abeta peptides.
219 PKalpha2 for ubiquitination and degradation, and thereby promotes activation of the mTOR-HIF1alpha pa
220 hat induces an atypical NF-kappaB activation and thereby promotes bortezomib resistance in MM cells.
223 orylation of speckle-type POZ protein (SPOP) and thereby promoting SPOP degradation by the anaphase-p
224 ular tether, holding XRCC1 and PNKP together and thereby promoting the low-affinity interaction ident
225 rease macular pigment optical density (MPOD) and thereby protect against the development of age-relat
226 ay contribute to stress-related pathologies, and thereby provide a novel target for intervention.
227 nzilic acid rearrangement of 19-hydroxy Gdm, and thereby provides a new synthetic derivatization stra
228 ine quality for rare versus common variants) and thereby provides insight into sequencing characteris
229 ty between the OFC and the rest of the brain and thereby reconfigures functional networks in the OFC.
233 astrocytes, and extracellular acidification, and thereby reduce susceptibility to epileptic seizures.
234 minimize the exposure of V3 non-NAb epitopes and thereby reduce their immunogenicity by introducing N
235 l to allow earlier culling of infected herds and thereby reduce transmission and aid the control of e
237 of EhRab35 reduced phagocytic cup formation and thereby reduced RBC internalization, suggesting a po
238 3 proteins via a proteasome-mediated pathway and thereby reduces the activity of the plasma membrane
239 can lead to localization of coherent phonons and thereby reduces the lattice thermal conductivity kap
240 cific microvascular transcriptional programs and thereby regulate angiodiversity are largely elusive.
241 oproteins or glycolipids on the cell surface and thereby regulate cell activation, migration, adhesio
242 djacent or distant specific recipient cells, and thereby regulate gene expression and activation of t
243 promote the biogenesis of secretory granules and thereby regulate hormone sorting and secretion.
244 ROS locally in response to various stimuli, and thereby regulate many cellular processes, but their
247 enotransplantation for treatment of diabetes and, thereby, represents a previously unidentified appro
248 etion of LSD1 increases the level of H3K9me2 and thereby represses expression of the LSD1-E2F1 cotarg
250 in infancy is affecting microbiota stability and thereby resistance against respiratory tract infecti
252 t kinetochores and decouple sisters in vivo, and thereby separately probe Hec1's role on polymerizing
253 regulate gene expression in distant tissues and thereby serve as a previously undescribed form of ad
254 Atad3a suppresses Pink1-dependent mitophagy and thereby serves a key role in hematopoietic homeostas
255 t MF6p/HDMs can transport heme in trematodes and thereby shield the parasite from the harmful effects
256 mimic specifically lowered IFITM1 expression and thereby significantly dampening KSHV infection.
257 dvantage of wide operational voltage window, and thereby significantly enhance the energy density.
259 ly modified microtubules for cargo transport and thereby spatially restrict focus formation to the pe
261 ll carbon nanotubes (SWCNTs) from the liquid and thereby stabilized against the highly exothermic rea
264 lso promote antigen-presenting cell function and thereby stimulate adaptive T cell-mediated anti-canc
265 lipopolysaccharide (LPS) in the circulation and thereby stimulates glucagon-like peptide 1 (GLP-1)-m
267 ransmitter receptors and signaling molecules and thereby support long-term plasticity of synaptic con
268 d tumour suppressors promote nutrient uptake and thereby support the survival and growth of cancer ce
269 through changes in exon-intron organization and thereby supported the evolution of a major morpholog
274 apable of sequestering the metal ion engines and thereby suppressing the catalytic activity, with dif
275 rane curvature to recruit lipidated proteins and thereby synergistically regulate the trafficking and
276 effectively shut down mature mRNA transport and thereby tailor protein synthesis to maintain energy
277 ogy to assess and monitor plaque instability and thereby test potential plaque-stabilizing drugs.
278 e the host to manipulate the gene expression and thereby the behavior of its bacterial colonizers.
279 ining the degree of their spatial spreading, and thereby the degree of the spine specificity of the s
282 ws us to follow the change in anchor density and thereby the strength of the skeleton/membrane attach
284 ough static water contact angle measurements and, thereby, the effective refractive indices the trans
286 s PABPC1 protein synthesis in cardiomyocytes and thereby titrates cellular translation in response to
289 and the hyperexcitability of sensory neurons and thereby to reduce pain in patients treated with this
291 exist between this archetypal pair of atoms, and thereby to test the fundamental principles on which
293 y lead to differences in chromatin structure and, thereby, transcriptional control, at the enhancer a
294 to interact with the nascent neural network, and thereby trigger immediate plastic and reversible sin
295 e IKKvarepsilon phosphorylated YAP at Ser403 and thereby triggered degradation of YAP in lysosomes an
297 ibly enter a quiescent, chemoresistant state and thereby underscore the need for combinatorial approa
299 f the components in the resulting assemblies and thereby valuable insight into the 2D heteroepitaxial
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