ライフサイエンスコーパス: androgenic

1 Is T-stimulated neuronal activation androgenic?

2 at are regulated by testosterone (T) and its androgenic (5alpha-dihydrotestosterone; DHT) or estrogen

3 s that could be potential in vivo targets of androgenic action during puberty.

4 In addition to the inhibition of androgenic activation of the AR, forced expression of FO

5 ndergone conventional biotreatment had lower androgenic activities.

6 Analyses included in vitro assays for androgenic activity (binding to goldfish testis androgen

7 onate-androst-5-ene-7,17-dione] that have no androgenic activity and could also block the Adiol-induc

8 t and wood GCI profiles were correlated with androgenic activity and neurotransmitter enzyme inhibiti

9 tenediol or Adiol) is a natural hormone with androgenic activity and that two potent antiandrogens, h

10 Reduced in vitro androgenic activity appears to be related to steroid rin

11 Because increased androgenic activity has been linked to prostate cancer a

12 itself may represent a natural hormone with androgenic activity in human prostate cancer cells.

13 tivity while having only moderate to minimal androgenic activity in vivo.

14 The androgenic activity of Adiol itself, however, is poorly

15 In vitro androgenic activity of the AD and T solutions decreased

16 ity on muscle, strongly dissociated from the androgenic activity on prostate after oral dosing.

17 on levator ani muscle, dissociated from the androgenic activity on ventral prostate, after oral dosi

18 reporter gene assays for estrogenic and anti-androgenic activity were performed on bottled water extr

19 to 4 mg/kg) administration of HB showed low androgenic activity when tested in the Hershberger assay

20 fects (cyto-genotoxicity, estrogenic or anti-androgenic activity) in vitro at relevant consumer-expos

21 All effluents and wood contained androgenic activity, particularly in nonpolar fractions,

22 ved from testosterone and have markedly less androgenic activity, promote tissue growth and enhance t

23 hat certain photoproducts retain significant androgenic activity, which has implications for exposure

24 ause hair loss may be a surrogate measure of androgenic activity-possibly a determinant of coronary a

25 the androgen receptor as well as the highest androgenic activity.

26 x-specific effects of phthalates having anti-androgenic activity.

27 rein is provided information on the anabolic-androgenic agents androstenedione, dehydroepiandrosteron

28 ne, one of the most commonly abused anabolic androgenic agents.

29 lyses conclude that finasteride treatment of androgenic alopecia (AGA) is safe but do not assess qual

30 receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)).

31 Acne and androgenic alopecia are prevalent but unreliable markers

32 onducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly

33 finasteride (Propecia) for the treatment of androgenic alopecia is unknown.

34 ed to treat benign prostatic hyperplasia and androgenic alopecia, but the role of 5alpha-dihydrotesto

35 tions, such as acne vulgaris, hirsutism, and androgenic alopecia.

36 Self-administration of large doses of androgenic-anabolic steroids (AAS) in a significant port

37 ranes as a potential site of intersection of androgenic and Akt1 signaling.

38 ve in established rodent models that measure androgenic and anabolic properties of these agents.

39 As brain testosterone plays both androgenic and estrogenic actions due to its conversion

40 the fetal pancreatic responses to MI-TP, and androgenic and estrogenic contributions to such response

41 Both androgenic and estrogenic steroids have been implicated

42 differentially influence the availability of androgenic and estrogenic substrates, depending on the r

43 potential adverse events while retaining the androgenic and gonadotropin suppressive actions.

44 kinase may be an important new link between androgenic and growth factor signaling and a novel thera

45 c acid biosynthesis and to the metabolism of androgenic and neuroactive 3alpha-hydroxysteroids.

46 The level of oestrogenic, androgenic and progestagenic activity observed is not co

47 (BPA) has been shown to modulate estrogenic, androgenic, and anti-androgenic effects.

48 r action as BPA (estrogenic, antiestrogenic, androgenic, and antiandrogenic) in vitro and in vivo.

49 vitro bioassays for (anti)estrogenic, (anti)androgenic as well as retinoic acid- and vitamin D-like

50 e ages of 4-13 years, a period marked by the androgenic changes of adrenarche.

51 ntial implications for the choice of current androgenic compounds and the development of future agent

52 represent potential markers for screening of androgenic compounds in the zebrafish embryo.

53 .6-4.8 ng DHTEq L(-1)) but concentrations of androgenic compounds were largely unable to account for

54 ctive and inactive nucleosomes under varying androgenic conditions showed that the relative CK2 activ

55 These results provide new insights into androgenic control of c-Fos and use of PKC inhibitors in

56 rostate growth and differentiation are under androgenic control, and prior studies suggested that tum

57 (S)-7c exhibited an overall partial androgenic effect but full anabolic effect via oral admi

58 gene, whereas, we provided evidence that the androgenic effect is mediated by E2F1 protein through a

59 emicals individually for their possible anti-androgenic effect.

60 nism and can be used as a measure of central androgenic effect.

61 hromosome-encoded oncogene in addition to an androgenic effect.

62 apoptosis, and present a new model for this androgenic effect.

63 Importantly, minimal androgenic effects (increased tissue weights) were obser

64 these chemicals have been shown to have anti-androgenic effects both in vitro and in vivo.

65 on, fairly little attention has been paid to androgenic effects in a female system, and even fewer st

66 gestins, such as levonorgestrel (LNG), exert androgenic effects in mammals by activating the androgen

67 ood testosterone levels or produces anabolic androgenic effects is not known.

68 rogen in fish supporting the contention that androgenic effects of certain progestins contribute to t

69 l and laboratory changes primarily reflected androgenic effects of prasterone.

70 Androgenic effects were found at LNG concentrations >/=4

71 steroid hormones leads to estrogenic and/or androgenic effects which may be important in age-related

72 Tibolone has estrogenic, progestogenic, and androgenic effects.

73 otective action on mammary gland may involve androgenic effects.

74 to modulate estrogenic, androgenic, and anti-androgenic effects.

75 an mixture risk assessment approach for anti-androgenic exposures in fetal life.

76 Through molecular screening of an androgenic gland (AG) cDNA library prepared from the cra

77 rate for the first time that p66Shc mediates androgenic growth signals in androgen-sensitive human pr

78 ), which is transcriptionally induced by the androgenic hormone 5alpha-dihydrotestosterone (DHT).

79 tic prostate epithelial cells in response to androgenic hormones and has found widespread use in canc

80 Genes regulated by androgenic hormones are of critical importance for the n

81 Genes regulated by androgenic hormones are of critical importance for the n

82 Genes regulated by androgenic hormones are of critical importance for the n

83 tress conditions, such as trauma-hemorrhage, androgenic hormones have immunosuppressive effects, lead

84 hese data suggest that DHT and perhaps other androgenic hormones may protect normal females against t

85 Androgenic hormones modulate the production of reproduct

86 NA in situ hybridization and is regulated by androgenic hormones.

87 d sensitivity to and endogenous synthesis of androgenic hormones.

88 ostate gland is an important target organ of androgenic hormones.

89 ivity, but testosterone is both anabolic and androgenic in doses that adolescents might receive.

90 rogen, whereas multi-copies of motif A exert androgenic inducibility for a heterologous promoter inde

91 G had a significant inhibitory effect on the androgenic inducibility of the PSA promoter.

92 These data suggest that the androgenic induction of endothelial MMP2 is a critical r

93 n PCNA immunoreactivity, suggesting that the androgenic induction of PCNA is mediated through the and

94 ately 60%) in prostate cancer (CaP) leads to androgenic induction of the ETS-related gene (ERG) expre

95 bird vocal control center, HVC, requires the androgenic induction of vascular endothelial growth fact

96 oncentrations may not accurately reflect the androgenic influence within specific tissue microenviron

97 ver, moieties modulating the actions of this androgenic insulin-like growth factor were yet to be rev

98 s were sensitive to testosterone but not its androgenic metabolite dihydrotestosterone.

99 oupled with the documented effects of DHEA's androgenic metabolites on visual-spatial performance, su

100 cations have been ascribed to compounds with androgenic or estrogenic properties, little attention ha

101 Direct estrogenic, androgenic, or steroidogenic mechanisms are unlikely for

102 artial borderline tumor), one patient had an androgenic ovarian tumor and two patients had hyperreact

103 otential to interact with the estrogenic and androgenic pathways, and could help prioritize chemicals

104 that adult male S. parvus maintain a unique androgenic phenotype, in which androgen receptor (AR) in

105 enzyme catalyzing estrogen biosynthesis from androgenic precursors, can be labeled in vivo with (11)C

106 responsible for catalyzing the production of androgenic precursors, while CYP19 converts testosterone

107 Both men and women produce E2 locally from androgenic precursors.

108 Oestrogenic, androgenic, progestagenic and glucocorticoid activity wa

109 NT-PGC-1alpha is sufficient to link beta(3)-androgenic receptor activation to adaptive thermogenesis

110 us, shaping of the EOD waveform involves the androgenic regulation of a rapidly inactivating splice f

111 However, the molecular mechanism underlying androgenic regulation of Bcl-2 in prostate cancer cells

112 APK), PI3K, and PKCdelta are involved in the androgenic regulation of c-Fos through controlling MEK/E

113 However, an investigation of the androgenic regulation of PCNA protein stability indicate

114 Androgenic regulation of Wnt signaling has been reported

115 liver specificity of the rat Std gene; (ii) androgenic repression of the gene requires the presence

116 Androgenic repression of the Std gene in rat liver can b

117 endogenously produced trophic factors in the androgenic rescue of SNB motoneurons and further suggest

118 ction is a biomarker assay for the undesired androgenic responses in vivo.

119 for physical signals drives the evolution of androgenic sensitivity in select neuromotor pathways.

120 d its emergence is associated with increased androgenic sensitivity within the hind limb musculature.

121 a gender-specific ILP was identified as the androgenic sex hormone in Crustacea.

122 ut older generation progestins have unwanted androgenic side effects in humans.

123 lective anabolic response with minimal or no androgenic side-effects and begin to elucidate the putat

124 monstrating a positive feedback mechanism of androgenic signalling in CRPC.

125 Androgenic signals provide feedback at many levels of th

126 al significance of this finding in mediating androgenic skin disorders such as acne, hirsutism, or an

127 e of trkB, trkC, or CNTFRalpha prevented the androgenic sparing of SNB motoneurons when antagonists w

128 The molecular basis for the enzyme's androgenic specificity and unique catalytic mechanism ca

129 ghly substrate selective, it is the hallmark androgenic specificity that sets aromatase apart.

130 oncordant with gene activity specific to the androgenic status.

131 vior after systemic exposure to the anabolic-androgenic steroid (AAS) 17alpha-methyltestosterone (7.5

132 Illicit anabolic-androgenic steroid (AAS) abuse, though an important publ

133 castrated and treated daily with an anabolic-androgenic steroid (AAS) compound (either stanozolol, ox

134 d and treated with 1 of 3 different anabolic-androgenic steroid (AAS) compounds (17 alpha-methyltesto

135 The effects of anabolic-androgenic steroid (AAS) compounds on spatial working me

136 ally intact male rats exposed to an anabolic androgenic steroid (AAS) during puberty.

137 the interactive effects of chronic anabolic androgenic steroid (AAS) exposure and brain serotonin (5

138 In hamsters (Mesocricetus auratus), anabolic-androgenic steroid (AAS) exposure during adolescence fac

139 In hamsters (Mesocricetus auratus), anabolic-androgenic steroid (AAS) exposure during adolescence fac

140 Repeated high dose (5.0 mg/kg) anabolic-androgenic steroid (AAS) exposure during adolescence sti

141 In hamsters, adolescent anabolic-androgenic steroid (AAS) exposure facilitates offensive

142 Prolonged high-dose anabolic-androgenic steroid (AAS) use has been associated with ps

143 ted in the modulation of adolescent anabolic-androgenic steroid (AAS)-induced aggression.

144 a to hepatocellular carcinoma after anabolic androgenic steroid abuse has been rarely reported.

145 inoma occurring in association with anabolic androgenic steroid abuse should sensitize physicians and

146 e oligonucleotide probes consist on anabolic androgenic steroid haptens (AAS) covalently linked to sp

147 ce waters, two of the most commonly observed androgenic steroid hormones are androstenedione (AD) and

148 Continuous use of anabolic androgenic steroid in high-doses is associated with subs

149 Short-term anabolic androgenic steroid use affects brain neurochemistry, inc

150 Androstenedione is an anabolic androgenic steroid used to increase blood testosterone l

151 Field studies of illicit anabolic-androgenic steroid users suggest that some develop manic

152 We postulated that exemestane-a mildly androgenic steroid-might have a less detrimental effect

153 Adolescent exposure to anabolic androgenic steroids (AAS) alters the development and act

154 Anabolic androgenic steroids (AAS) are illicitly administered to

155 Anabolic androgenic steroids (AAS) can promote detrimental effect

156 dministration of excessive doses of anabolic androgenic steroids (AAS) disrupts reproductive function

157 Chronic treatment with anabolic-androgenic steroids (AAS) during adolescence alters the

158 thors examined the effects of three anabolic-androgenic steroids (AAS) during puberty: testosterone,

159 Illicit use of anabolic androgenic steroids (AAS) has become a prevalent health

160 of the hallmarks of illicit use of anabolic androgenic steroids (AAS) is disruption of behaviours un

161 Treatment with anabolic-androgenic steroids (AAS) throughout adolescence facilit

162 Therefore, several commonly abused anabolic-androgenic steroids (AAS) were tested for their ability

163 ns of individuals have used illicit anabolic-androgenic steroids (AAS), but the long-term cardiovascu

164 y is associated with illicit use of anabolic-androgenic steroids (AAS).

165 ndividuals who illicitly administer anabolic androgenic steroids (AAS).

166 ddition to an action on metabolism, anabolic/androgenic steroids also increase sex drive and mental a

167 preferential substrate specificity for C-19 androgenic steroids and C-24 bile acids.

168 fotransferase (Std) catalyzes sulfonation of androgenic steroids and certain aromatic procarcinogens.

169 ed for the analysis of natural and synthetic androgenic steroids and their selected metabolites in aq

170 Exogenous androgenic steroids applied to pregnant sheep programmes

171 Changes in 5-HIAA levels caused by anabolic androgenic steroids are related to the behavioral change

172 Androgenic steroids are required to maintain the prostat

173 Anabolic androgenic steroids are synthetic derivatives of testost

174 Anabolic androgenic steroids are used to enhance athletic perform

175 Non-androgenic steroids did not change PCNA immunoreactivity

176 Athletes often take androgenic steroids in an attempt to increase their stre

177 de and sulfate metabolites of seven anabolic-androgenic steroids in urine.

178 ily is responsible for the conversion of C19 androgenic steroids to the corresponding estrogens, a re

179 t are capable of surviving in the absence of androgenic steroids were found to express protein kinase

180 ding the use of illicit substances, anabolic-androgenic steroids, herbal products, and medications.

181 es had increased apoptosis in the absence of androgenic steroids, whereas similarly grown tumors and

182 o survive, grow and spread in the absence of androgenic steroids.

183 lude that the pancreas is a primary locus of androgenic stimulation during development, giving rise t

184 However, a low level of androgenic stimulation may continue, even after castrati

185 Because heightened androgenic stimulation may increase risk of prostate can

186 etastatic prostate cancer has been to reduce androgenic stimulation of tumor growth by removal of the

187 ized as an androgen-responsive gene, and the androgenic stimulation regulates the development and gro

188 hSef expression was not influenced by androgenic stimulation.

189 ate cancer cells and functions downstream of androgenic stimulation.

190 leted medium or in response to physiological androgenic stimulation.

191 Androgenic stimulus in rat prostate modulates its associ

192 ase (CYP17), the enzyme that synthesizes the androgenic substrate for aromatase.

193 Using an ABCA1 promoter-reporter gene assay, androgenic suppression was observed at the transcription

194 Metabolites of androgenic synthetic growth promoters used at confined a

195 winning were likely exclusive to the neural androgenic system because they have no detectible impact

196 strated that the progestins are all strongly androgenic, thereby explaining the masculinization effec

197 tion in Longissimus dorsi muscle confirm the androgenic treatment in experimental animals.

198 o the relative lack of literature concerning androgenic versus estrogenic hormones in environmental m