ライフサイエンスコーパス: anemic

1 ythropoiesis, though K-Ras(-/-) embryos were anemic.

2 Cdc42GAP-/- mice were anemic.

3 s to decide whether the patient is, in fact, anemic.

4 6471 men (21.7%) and 4659 women (30.4%) were anemic.

5 n and 10.2% of women 65 years and older were anemic.

6 h chronic heart failure (CHF) are frequently anemic.

7 Sixty-one percent of the CHF patients were anemic.

8 dred men (4.8%) and 1,058 women (13.0%) were anemic.

9 , pancreas, and the digestive tract and were anemic.

10 ted that 60% of pregnant women worldwide are anemic.

11 were normal, and the mutant animals were not anemic.

12 all patients, and five of seven were mildly anemic.

13 of subjects were HIV positive and 15.1% were anemic.

14 s frequently delayed, and some donors become anemic.

15 ty-seven percent of the study population was anemic.

16 balamin concentrations; only one subject was anemic.

17 his infection persists and he remains mildly anemic.

18 s likely to smoke (41 versus 52%), were more anemic (23 versus 7%), and were more likely to live in p

19 10 patients (53%) were still anemic 6 months after ICU discharge.

20 ey rats weighing 200-300 g, 38 of which were anemic (80-90 g/L) and 11 with normal hemoglobin levels.

21 st management (IPM) continues to suffer from anemic adoption rates in developing countries.

22 d that the hypoxic induction of liver Epo in anemic adults was Hif-2alpha dependent.

23 w that mice deleted for Rcor1 are profoundly anemic and die in late gestation.

24 Stat5a/b(-/-) mice are severely anemic and die perinatally, but no link has been made to

25 ic lethality, but double KO embryos are more anemic and die sooner than either single KO.

26 Thereafter, the nu/nu mice became anemic and died, whereas the nu/+ mice produced antimala

27 rine 191 phosphorylation site are runted and anemic and display splenomegaly.

28 acrophage protein null phenotype is severely anemic and embryonic lethal.

29 l erythroblasts and the Rb null phenotype is anemic and embryonic lethal.

30 Syrian hamsters become anemic and exhibit delayed growth following oral infecti

31 wever, IFNgamma-knockout mice did not become anemic and had greater numbers of splenic erythroid prec

32 e, which, like hypotransferrinemic mice, are anemic and incur iron loading, but have functional Tf.

33 on nutriture and a reduced risk of remaining anemic and iron deficient.

34 57BL/6 mice given adult worms rapidly became anemic and lost weight in a manner similar to AWT hamste

35 attributable to ehrlichiosis, both dogs were anemic and neutropenic and the Thai dog was thrombocytop

36 ive outcomes variables were compared between anemic and nonanemic neonates.

37 ravenous iron improves exercise tolerance in anemic and nonanemic patients with symptomatic chronic h

38 fied as stunted and obese and 1.4% were both anemic and overweight compared with expected prevalences

39 that mutant mice with a reduced serum PA are anemic and prone to phenylhydrazine-induced anemia.

40 phases at two hematocrit (Hct) values: 30% (anemic) and 42% (physiologic; normalized by treatment wi

41 Forty percent of patients were anemic, and 21% either had elevated total plasma homocys

42 a quarter of the world's population remains anemic, and about half of this burden is a result of iro

43 hei ANKA infection compared to asymptomatic, anemic, and control groups.

44 ly 25% smaller than normal littermates, very anemic, and died on the day of birth.

45 W mutant mice are severely anemic, and earlier work suggested that this defect in e

46 ntly older when HU was instituted, were more anemic, and more likely to have BAN or CAM haplotypes.

47 mice, SJL-Kit(W/W-v) mice are MC-deficient, anemic, and neutropenic and have normal T cell compartme

48 Hypoalbuminemic, anemic, and obese patients on MHD had a worse QoL.

49 s died during gestation, frequently appeared anemic, and suffered from a lack of Ter-119-positive ery

50 al apoptosis in anemic rats when compared to anemic animals not undergoing transfusion.

51 sion of fresh blood to 100 g/L hemoglobin in anemic animals offers cardioprotection after acute myoca

52 survival were significantly improved in the anemic animals undergoing fresh blood transfusion compar

53 Anemic animals were randomized to receive fresh blood (w

54 Treatment of anemic animals with Euk-8, a catalytic antioxidant with

55 survival was dramatically decreased in these anemic animals, partially compensated by considerable en

56 fresh blood transfusion compared to control anemic animals.

57 ; 95% CI: -3.99, -0.96) in children who were anemic at baseline and decreased Atlantis delayed scores

58 Overall, 1277 patients (34%) were anemic at baseline, which persisted through discharge in

59 all, 44.6% of women studied (n = 37/83) were anemic at delivery, and 18% of women (n = 11/61) had IDA

60 EKLF(-/-)KLF2(-/-) mice appear anemic at embryonic day 10.5 (E10.5) and die before E11.

61 KLF1(-/-) KLF2(-/-) double knockout mice are anemic at embryonic day 10.5 (E10.5) and die by E11.5, i

62 anemia at one year in patients who were not anemic at entry and who were randomized to enalapril or

63 tudy with blinded end point assessment among anemic (average hemoglobin of 10.4+/-1 g/dL) older adult

64 In anemic awake sheep, stored renitrosylated, but not contr

65 Administration of 3 SCFADs in anemic baboons increased F-reticulocytes 2- to 15-fold o

66 ATF4 null fetuses were severely anemic because of an impairment in fetal-liver definitiv

67 and the animals reached normal age but were anemic because of low erythropoietin levels.

68 weeks, and after 5 weeks the mutants became anemic, began to lose weight, and die.

69 In contrast, in anemic beta-thalassemia intermedia mice, there is altere

70 opoietin therapy randomized to normal versus anemic blood hemoglobin concentration.

71 at women complaining of fatigue who were not anemic but who had reduced or absent iron stores were sy

72 Women who are not anemic but who suffer from fatigue may benefit from iron

73 Surprisingly, the patient's father is not anemic, but he is a smoker with high levels of HbCO ( ap

74 -/-) mice and littermates that were rendered anemic by bleeding.

75 Conversely, older blacks classified as anemic by WHO criteria were not at risk for adverse even

76 lfa overcame much of the QOL deficit seen in anemic cancer patients compared with the norm population

77 the functional status and quality of life in anemic cancer patients receiving chemotherapy, as well a

78 meters, quality of life (QOL), and safety in anemic cancer patients receiving nonplatinum chemotherap

79 al evaluating epoetin alfa versus placebo in anemic cancer patients.

80 Anemic cats with chronic renal failure represent a poten

81 posterior mesoderm of wild-type embryos and anemic cdx4(-/-) mutants, indicating a link between the

82 Mice deficient for HDAC5 show resistance to anemic challenge and altered marrow responsiveness to er

83 echanism contributing to the poor outcome in anemic CHF patients.

84 h overweight or obese mothers, 12.6% have an anemic child and 14% have a zinc-deficient child.

85 on cognition and impaired working memory in anemic children and long-term memory and retrieval in gi

86 and peripheral blood (n = 70) of Mozambican anemic children by quantitative polymerase chain reactio

87 Severely anemic children might particularly benefit from routine

88 he change in the hemoglobin concentration of anemic children was significantly different between fort

89 One hundred forty-one severely anemic children were identified during the baseline asse

90 All severely anemic children were randomly assigned to receive either

91 ts were made in randomly selected 7-12-y-old anemic children with documented Schistosoma haematobium

92 This study found that severely anemic children with Plasmodium falciparum infection hav

93 Among iron-deficient or anemic children, hemoglobin concentrations were improved

94 on effect: 0.90; 95% CI: 0.18, 1.62), and in anemic children, iron increased scores in the Atlantis D

95 deficits were observed in iron-deficient or anemic children, particularly with longer-duration, lowe

96 merican women would have been classified as "anemic" compared with 5.3% of whites.

97 itory factor (MIF) in the development of the anemic complications and bone marrow suppression that ar

98 e to malaria infection and the likelihood of anemic complications.

99 d at the transcriptional level under hypoxic/anemic conditions.

100 1988-1994) revealed that only a minority of anemic CRI subjects in the United States met these K/DOQ

101 Overall risk of mortality in severely anemic critically ill bloodless patients appeared to be

102 In this study of anemic critically ill patients treated with epoetin alfa

103 Anemic critically ill patients treated with IV iron and

104 did not predict pharmacodynamic response in anemic critically ill patients.

105 stored leukodepleted red cells to euvolemic, anemic, critically ill patients has no clinically signif

106 ese data, routine IV iron supplementation of anemic, critically ill trauma patients cannot be recomme

107 CE knockout mice, which lack tissue ACE, are anemic despite having normal renal function.

108 reatments) is superior to no iron therapy in anemic dialysis patients receiving adequate epoetin dosa

109 We report here that fit1 mutants are anemic, display numerous peripheral blood defects, and a

110 Homozygous Nrf-1 mutant mice are anemic due to a non-cell autonomous defect in definitive

111 The steroid-free group was more anemic early posttransplantation (P=0.004), suggesting a

112 hematocrit level is corrected to healthy in anemic Epo-TAg(h) mice.

113 Stat5a-/-5b-/- embryos are severely anemic; erythroid progenitors are present in low numbers

114 served during acute chest syndromes or acute anemic events (AAE), and extracranial internal carotid a

115 udin et al have identified the rate of acute anemic events (AAEs) and extracranial internal carotid a

116 Acute anemic events are common in children with SCD and preval

117 155-920) per 100 patient-years during acute anemic events for all patients.

118 e (SCD), could occur in the setting of acute anemic events.

119 Our aim was to follow patients discharged anemic from the intensive care unit (ICU) for up to 6 mo

120 according to hemoglobin levels (<12.5 g/dl [anemic group] vs. 12.5 to 14.5 g/dl [nonanemic group]).

121 erence in one-year survival was noted in the anemic groups compared with no anemia group (adjusted ha

122 e, alleviating anemia, and improving HRQL in anemic (Hb < or = 12 g/dL) HCV-infected patients receivi

123 l infarction was two to five times higher in anemic (Hb <12 g/dl) patients than in people with Hb fro

124 ndomized hemoglobin (Hb) correction study in anemic (Hb</=10.0 g/dl) patients incident to hemodialysi

125 ness of growth factor therapy in maintaining anemic HCV-infected patients on target drug levels durin

126 Mean HRQL scores of anemic HCV-infected patients receiving combination thera

127 intained RBV dose and improved QOL and Hb in anemic HCV-infected patients receiving combination thera

128 life (QOL), and increase hemoglobin (Hb) in anemic HCV-infected patients.

129 iesis-stimulating agents in the treatment of anemic heart failure patients, clinical trial data, to d

130 ic gluconate to improve hemoglobin levels in anemic hemodialysis patients who were receiving adequate

131 Few data exist to guide treatment of anemic hemodialysis patients with high ferritin and low

132 hemoglobin and allows lower epoetin doses in anemic hemodialysis patients with low TSAT and ferritin

133 group (from 60 to 20%) but increased in the anemic hemoglobin group (from 57 to 86%).

134 7, target hemoglobin of 14 +/- 1 g/dl) or an anemic hemoglobin group (n = 18, target hemoglobin 10 +/

135 The anemic hemoglobin group had a progressive increase in er

136 The anemic hemoglobin group had higher CD8 counts compared w

137 Overall, 62.3% of children were anemic (hemoglobin < 110 g/L), and 82.7% of anemia was a

138 sent in 34 (12%) children, and 37 (13%) were anemic (hemoglobin < 110 g/L).

139 SP) on erythropoietin production in severely anemic (hemoglobin < or = 70 g/L) preschool children in

140 with additional iron folic acid if they were anemic (hemoglobin <11 g/dL).

141 concentrations and hematocrit percentages in anemic (hemoglobin concentration <12 g/dL) Indian women

142 lled treatment trial was conducted among 546 anemic (hemoglobin concentration, 7-11 g/dL) children ag

143 es and malaria after iron supplementation in anemic (hemoglobin: 70-109 g/L) children aged 2-35 mo.

144 e 7.7 to 16.4 g/dl) and 184 women (21%) were anemic (Hgb <12 g/dl).

145 The non-anemic hippocampal iron-deficient mouse demonstrated upr

146 omen) who enrolled in a prospective study of anemic HIV-1-infected patients requiring transfusion.

147 Iron supplementation in anemic HIV-infected children has beneficial effects on h

148 No rats were anemic, hypoglycemic, or hypotensive before CCI.

149 cific tolerance of different levels of acute anemic hypoxia.

150 al and urban families were less likely to be anemic if they received fortified milk [odds ratio (OR):

151 nts were significantly less likely to become anemic if uninterrupted postpartum participation lasted

152 Furthermore, Ncoa4(-/-) mice are anemic in perinatal periods and fail to respond to TH by

153 n in nonpregnant Cambodian women screened as anemic.In this 2 x 2 factorial, double-blind, randomized

154 In anemic individuals, iron deficiency often not only decre

155 e major cause of tissue-iron accumulation in anemic iron-overload disorders caused by hemolytic anemi

156 may be a novel therapeutic target in several anemic iron-overload disorders.

157 kely contributing to an otherwise relatively anemic level of horizontal gene transfer, which neverthe

158 Patients who became anemic (levels of hemoglobin approximately </=10 g/dL) d

159 matopoietic growth factors for patients with anemic low/intermediate-1 IPSS (n = 94), and hypomethyla

160 We treated 8 anemic MDS patients (refractory anemia [RA] and refracto

161 U/L; P<0.01), these patients were moderately anemic (mean+/-SD; hemoglobin =118+/-17 g/L).

162 Anemic men and women were older and had a higher percent

163 OBHRE-Epo corrected the hematocrit level in anemic mice to a normal physiologic level that stabilize

164 rythropoiesis was induced in both normal and anemic mice, a process that was completely reversible.

165 EPO-generating organs of hypoxic or acutely anemic mice, acetate levels rise and ACSS2 is required f

166 In acutely anemic mice, acetate supplementation augments stress ery

167 e marrow cells from phenylhydrazine-treated, anemic mice, we find that both gp55-A and gp55-P induce

168 rythroid spleen cells and reticulocytes from anemic mice.

169 ntly activated in both HSC and MPP1 cells in anemic mice.

170 Although chronically anemic, most animals survived for 2 to 9 months and were

171 GM-CSF) and erythropoietin (epoetin alfa) in anemic, neutropenic patients with myelodysplastic syndro

172 Two-thirds of the infants were mildly anemic, no treatment effects on hemoglobin concentration

173 n (odds ratio: 3.47; 95% CI: 1.51, 7.96) and anemic (odds ratio: 2.92; 95% CI: 1.24, 6.90) children h

174 icians, and the target patient population is anemic or iron-deficient adult patients with heart disea

175 altered in mice that were thrombocytopenic, anemic, or leukopenic.

176 st this stage have normal morphology but are anemic owing to failed definitive erythropoiesis, caused

177 Random assignment of anemic participants to intervention and control arms occ

178 ous and binary outcomes, respectively.Of 179 anemic participants, 136 (76.0%) completed all follow-up

179 a particularly high risk of mortality among anemic patients <65 years of age (P=0.07).

180 ESAs were permitted for anemic patients (hemoglobin [Hb] <10 g/dL) after RBV dos

181 Thirty-eight anemic patients (hemoglobin, median [interquartile range

182 In anemic patients (n = 18), the difference (95% CI) was 20

183 Anemic patients 5 years to 18 years of age receiving mye

184 Twenty-six anemic patients aged 57+/-11 years were randomized to re

185 in was eventually purified from the urine of anemic patients by Eugene Goldwasser in 1977.

186 Survival was reduced in anemic patients compared with patients with a normal hem

187 reduce the risk of transfusion in moderately anemic patients controlling for patient and ICU factors.

188 Anemic patients had a 3-fold higher mortality risk compa

189 More than 50% of anemic patients had a glomerular filtration rate <60 mL.

190 Anemic patients had a postoperative mortality and cardia

191 When compared with nonanemic patients, anemic patients had higher in-hospital mortality (3.0% v

192 ed to trigger red blood cell transfusions in anemic patients in critical care and acute care settings

193 ickled red blood cells (ISCs) of sickle cell anemic patients into the sickle shape.

194 The most anemic patients require regular red blood cell transfusi

195 Strikingly, it also identifies many pre-anemic patients several weeks before anemia becomes clin

196 t-effective anemia screening and chronically anemic patients to self-monitor their disease.

197 alence of hypoglycemia in critically ill and anemic patients treated with insulin and tight glucose c

198 Anemic patients were more likely to be receiving diureti

199 It is unclear if blood transfusion in anemic patients with acute coronary syndromes is associa

200 Blood transfusion is controversial for anemic patients with acute myocardial infarction (AMI),

201 thropoietin (EPO) on exercise performance in anemic patients with CHF.

202 escribe PS exposure in RBCs of 56 comparably anemic patients with different genetic backgrounds of th

203 Therefore, for anemic patients with hematologic malignancies it is reco

204 Therefore, for anemic patients with hematologic malignancies, it is rec

205 on was assessed in a subset of 37 ambulatory anemic patients with I131-tagged albumin to measure red

206 ersus SC alone (n = 57) for the treatment of anemic patients with lower-risk myelodysplastic syndrome

207 Purpose Most anemic patients with non-deleted 5q lower-risk myelodysp

208 Bone marrow was examined in 29 anemic patients with RA, 9 healthy volunteers, and 6 pat

209 -elevation acute coronary syndrome, although anemic patients with ST-elevation myocardial infarction

210 In the subset of 37 anemic patients, 17 patients (46%) had hemodilution and

211 uation of anemia was found in only 3% of all anemic patients, and better in internal medicine than in

212 s one of the main therapeutics used to treat anemic patients, greatly improving their quality of life

213 microglobulin and, in a subset of moderately anemic patients, improved blood hemoglobin levels.

214 Benefits were more evident in anemic patients.

215 sis was only slightly elevated (7 to 34%) in anemic patients.

216 ion for > or = 8 weeks) occurred in 10 of 17 anemic patients.

217 and VO2 relative to values in the untrained anemic phase.

218 which was previously shown to ameliorate the anemic phenotype.

219 ning the human beta globin gene locus and in anemic phlebotomized baboons.

220 gle-dose (500 mg) mebendazole among severely anemic pregnant women in periurban Karachi, Pakistan.

221 Alzheimer disease etiology in iron-deficient anemic rat pups at the time of hippocampal differentiati

222 of fresh vs. stored blood when transfused in anemic rats after acute myocardial infarction.

223 sed infarct size and myocardial apoptosis in anemic rats when compared to anemic animals not undergoi

224 d that DMT1 protein levels were increased in anemic rats.

225 pe 1 (RR, 0.78; 95% CI, 0.71, 0.86), or were anemic (RR, 0.70; CI, 0.60, 0.89).

226 oduct improved iron status in iron-deficient anemic soldiers but not in iron-normal or iron-deficient

227 concentrations were lower in iron-deficient anemic soldiers than in those with normal iron status (P

228 ed declines in iron status in iron-deficient anemic soldiers; a group-by-time interaction was observe

229 The severely anemic sph(1J)/sph(1J) mouse has very fragile red cells

230 induced erythropoiesis, such as during acute anemic states (see the related article beginning on page

231 impact upon erythropoiesis, particularly in anemic states that may require output from the spleen.

232 ematocrit (Hct) or hemoglobin to correct for anemic status (e.g., 20.7 +/- 5.7 mumol/L per % Hct [day

233 inerleukin-10, irrespective of iron status, anemic status, and general acute-phase response.

234 sed response of REPCs in fibrotic kidneys to anemic stimulation remain elusive.

235 lycythemic strain (gp55-P), but not from the anemic strain (gp55-A), activates the erythropoietin rec

236 terestingly, we find that the env gene of an anemic strain of Friend virus, Rauscher virus envelope g

237 -/- mice displayed exaggerated recovery from anemic stress and persistent cell cycling consistent wit

238 kt in the endothelium of mice results in non-anemic stress erythropoiesis in the spleen.

239 Acute anemic stress induces a physiological response that incl

240 Acute anemic stress induces a systemic response designed to in

241 appeared to respond appropriately to induced anemic stress.

242 It was possible to predict anemic subjects in the limited prospective blood donor p

243 However, the change in hemoglobin in anemic subjects was greater in the Fe group than in the

244 blast differentiation in vivo and alleviated anemic symptoms in a chronic anemia mouse model by regul

245 ice had increased splenomegaly and were more anemic than corresponding WT mice.

246 ugh rbc-specific Sphk1 Sphk2-KO embryos were anemic, the erythropoietic capacity of hematopoietic ste

247 Patients were classified as anemic using the World Health Organization definition (<

248 tions per 1000 patient-years of follow-up in anemic versus nonanemic patients (both P<0.001).

249 d increased intestinal expression of fpn1 in anemic weh(Tp85c-/-) adults.

250 production, comparable with that observed in anemic wild-type mice.

251 erozygous Lyn(+/up) mice became increasingly anemic with age, indicating that the mutation was domina

252 She was severely anemic, with a hemoglobin level of 6 g/dL, and was found

253 Adult Lyn(up/up) mice were anemic, with dysmorphic red cells (spherocyte-like, acan

254 receiving Sod2(-/-) cells were persistently anemic, with findings suggestive of a hemolytic process.

255 hemoglobin concentrations in rural Cambodian anemic women (aged 18-49 y) who cooked with the iron ing

256 ough the benefits of iron supplementation in anemic women are well recognized, insufficient data are

257 Anemic women had a higher risk of death from any cause (

258 Anemic women had higher creatinine and were more likely

259 Also, anemic women had shorter survival time free of adverse o

260 n multivariate models, but the proportion of anemic women who were iron deficient was considerably lo

261 alone in improving the hemoglobin status of anemic women.