ライフサイエンスコーパス: anilide

1 iometric C-H amination with these copper(II) anilides.

2 activity for hydroxamic acids and orthoamino anilides.

3 hemical dehydrohalogenation of corresponding anilides.

4 veniently synthesized from reactions between anilide 1 and phenyliodine(III) diacetate (PIDA) through

5 The unsubstituted anilide 12 had a K(i) value at A(2B) receptors of 1.48 n

6 resence of a broad scope of tertiary amides, anilide, 2-pyridone, and carbamate functionality.

7 -MB-231 and colon RKO cancer cell lines, the anilide 2b (salermide) and the phenylpropylthio analogue

8 Anilides 3b and 3c were used as vehicles to explore stru

9 Of these 16 new anilides administered orally as one 6 mg/kg dose combine

10 hloride and bromide substituents on both the anilide and aryl iodide coupling components.

11 III)-catalyzed protocol for the amidation of anilide and enamide C-H bonds with isocyanates has been

12 The electron-transfer behavior of anilides and dianilides was studied and led to the follo

13 riflate catalyzed selective C-benzylation of anilides and heteroaryl amides with benzyl chlorides hav

14 t k(cat)/K(m) for hydrolysis of tetrapeptide anilides at low ionic strength with a Bronsted slope alp

15 olinone rotational barriers about the chiral anilide axis were also studied using density functional

16 dem cyclizations of alpha-halo-ortho-alkenyl anilides bearing an additional substituent on the alpha-

17 pe of linkage with the pendant groups (i.e., anilide, benzamide) or the aromatic substitution pattern

18 rossover experiments established exchange of anilide (but not imido) ligands in the presence of free

19 and control of the molecular conformation of anilides by resonance effects.

20 r rare class of compounds, are prepared from anilides by the action of Dess-Martin periodinane (DMP)

21 -> pi*C horizontal lineO resonance in simple anilides can be varied by as much as 10 kcal/mol.

22 ment of Alzheimer's disease (AD) utilizes an anilide chemotype that engages a key residue (Gly230) in

23 The principal role of these copper(II) anilides [Cl2NN]Cu-NHAr is to capture the radical R(*) g

24 series of novel beta-diketiminato copper(II) anilides [Cl2NN]Cu-NHAr that participate in C-H aminatio

25 u-(t)OBu yields the corresponding copper(II) anilides [Cl2NN]Cu-NHAr.

26 Reaction of the uranium(III) tris(anilide) complex (THF)U(N[t-Bu]Ar)(3) (1, THF = tetrahyd

27 ([N(n-Bu)(4)][1]) with the uranium(III) tris(anilide) complex (THF)U(N[t-Bu]Ar)(3) (2; THF = tetrahyd

28 n performed with sterically hindered aniline/anilide complexes and nitroxyl radical species.

29 reactions of Os(IV) and Os(III) aniline and anilide complexes.

30 excited-state for the para-COPh-substituted anilide derivative and is not quenched by 0.15 M piperyl

31 human leukemia U937 cells, the benzamide and anilide derivatives 1b, 1c, 2b, and 2c as well as the 4-

32 ese antiproliferative effects is enhanced in anilide derivatives and translates into tumor growth inh

33 The optimization of a series of anilide derivatives of (R)-3,3, 3-trifluoro-2-hydroxy-2-

34 Sixteen new anilide derivatives of the natural trioxane artemisinin

35 mediated cyclization reaction of unsaturated anilides discovered during the total synthesis of the CP

36 ium-catalyzed intramolecular arylation of an anilide enolate.

37 io of hydrolysis of succinyl-Ala-Ala-Pro-Phe-anilides for p-nitroaniline versus aniline leaving group

38 A metal-free method for fast and clean anilide formation from perfluoroaryl azide and thioacid

39 ggesting a single electron transfer from the anilide functionality to IBX and implicating a radical-b

40 tantiate the hypothesis that the presence of anilide groups establishes a strong energetic preference

41 ith benzyl nitriles, aryl Weinreb amides and anilides have been evaluated for the transformation usin

42 oxidative addition of aniline to form a bis-anilide hydride complex, followed by migratory insertion

43 With the exception of suberoyl anilide hydroxamic acid and PXD101, all of the other HDA

44 xamic acids (oxamflatin, Scriptaid, suberoyl anilide hydroxamic acid, panobinostat [LBH589], and beli

45 hdrawing groups on the ortho position of the anilide, i.e., chloro, acetyl, or bromo, increased poten

46 ies is optimal (as measured by AUC) when the anilide is substituted at the 4-position with an electro

47 application of a novel lithium N-cyclohexyl anilide (LiCyan).

48 as well as the core pyrazoline ring and the anilide linker.

49 The anilide-methyl complex (PNP)Sc(NH[DIPP])(CH(3)) (1) [PNP

50 Although the anilide moiety affords excellent potency, it simultaneou

51 alicyloyl ring and hydrophobic groups in the anilide moiety for optimal activity.

52 l moiety for binding but lacked the phenolic anilide moiety.

53 The activity of the cinnamic anilide mPTP inhibitors turned out to be additive with t

54 ethylamides (n = 2) were active, most of the anilides (n = 0) turned out to moderately or strongly in

55 monodentate amide ligands - the m-terphenyl anilides [N(R){C6H3Ar2-2,6}](-) (Ar = aryl, R = H, methy

56 ries, an acyl group at the 2-position of the anilide of these thiophene sulfonamides improved oral bi

57 ylglycine methyl ester (PGME) linked through anilide or benzamide bonds were prepared (i.e., o-, m-,

58 and aralkyl amides demonstrated that simple anilides, particularly those substituted in the para-pos

59 The palladium-catalyzed direct arylation of anilides possessing several N-acyl substituents has been

60 talysis, undergo in situ trapping to provide anilide products.

61 No KIE or exchange with the anilide proton was observed when 1-d(3) was treated with

62 air, rt) of racemic alpha-halo-ortho-alkenyl anilides provide 3,4-dihydroquinolin-2-ones in high yiel

63 For all four complexes the anilide rings of the inhibitors overlap aromatic rings o

64 orter isopropylmethanoyl substituents of the anilide rings of UC-38/UC-84, which draws these rings cl

65 (CSPs) containing a subset of the amino acid anilide selector library was screened for enantioselecti

66 ity and local lipophilicity), applied to the anilide series suggests structural modifications to impr

67 Five simply substituted anilides show low-microM blockade of the MV, one of whic

68 such as glutathione (gammaGlu-Cys-Gly), and anilides, such as gamma-glutamyl-7-amido-4-methylcoumari

69 elopment of a series of substituted cinnamic anilides that represents a novel class of mitochondrial

70 Herein, we demonstrate that N-acylanilines (anilides), the first class of planar amides that have be

71 for the carboxylation of ortho-C-H bonds in anilides to form N-acyl anthranilic acids has been devel

72 tion with certain unsaturated N-aryl amides (anilides) to form heterocycles are described.

73 Addition of an H-atom to the Os(IV) anilide TpOs(NHPh)Cl(2) (Os(IV)NHPh) gives the Os(III) a

74 Palladium-catalyzed ortho-arylation of anilides was achieved using 2-aminophenyl-1H-pyrazole (2

75 gO as the promoter, mono- and diarylation of anilides were realized in up to 89% isolated yield.

76 A library of 36 L-amino acid anilides, which are potential selectors for chiral HPLC,

77 On the other hand, trimethyl ether galloyl anilides, with few exceptions, exhibited moderate to ver

78 nzoxazinones and quinazolinones, from simple anilides without installing and removing an external dir