ライフサイエンスコーパス: anion gap

1 ns in bedside monitoring tools (base excess, anion gap).

2 ess the effect of acute changes in pH on the anion gap.

3 a change in pH cause minimal changes in the anion gap.

4 01); and all relative to patients with delta anion gap 0-5 mEq/L.

5 ns as follows: adjusted anion gap = observed anion gap + 0.25 x ([normal albumin] [observed albumin])

6 1 +/- 3.6 vs. 3.6 +/- 1.5 mmol/L, p < .001), anion gap (28.2 +/- 4.1 vs. 15.6 +/- 3.1, p < .001), and

7 dence interval 0.67-0.81; p < 0.0001); delta anion gap 5-10 mEq/L odds ratio 1.56 (95% confidence int

8 We compared the base excess (BE) and anion gap (AG) methods with the less commonly used Fencl

9 Both patients had a positive urine anion gap, alkaline urine despite acidemia, no rise in u

10 ommon laboratory toxicities were an elevated anion gap, an increased total amylase level, neutropenia

11 The exposure of interest was delta anion gap and categorized a priori as <0, 0-5, 5-10, and

12 pital lengths of stay, time to correction of anion gap and ketone clearance, and hypoglycemic episode

13 ce between critical care initiation standard anion gap and prehospital admission standard anion gap i

14 base variables of pH, base deficit, lactate, anion gap, apparent strong ion difference, and strong io

15 imiting the cohort to patients with standard anion gap at critical care initiation of 10-18 mEq/L did

16 An increase in standard anion gap at critical care initiation relative to prehos

17 oncentrations; serum carbon dioxide content; anion gap; blood urea nitrogen level; and serum creatini

18 The observed anion gap can be adjusted for the effect of abnormal ser

19 These anion gap changes have been largely attributed to titrat

20 rs of serum does not explain the much larger anion gap changes of HCl acidosis and diuretic alkalosis

21 Time to anion gap closure and ketone clearance also decreased (b

22 are and hospital lengths of stay and time to anion gap closure and ketone clearance, without increasi

23 We hypothesized that the delta anion gap defined as difference between critical care in

24 s a quantitative relationship between excess anion gap (DeltaAG) and bicarbonate deficit (DeltaHCO(3)

25 Anion gap detected a hidden "gap acidosis" in only 31% o

26 The discrimination of delta anion gap for 30-day mortality was evaluated using recei

27 Several studies support correcting the anion gap for changes in albumin (and even phosphate).

28 dence interval 1.35-1.81; p < 0.0001); delta anion gap >10 mEq/L odds ratio 2.18 (95% confidence inte

29 glycol accumulation, as evidenced by a high anion gap (> or =15 mmol/L) metabolic acidosis with elev

30 Delta anion gap has similarly moderate discriminative ability

31 ate supportive measures and antidotes, serum anion gap higher than 24 mmol/L; or, serum methanol conc

32 n relative to prehospital admission standard anion gap is a predictor of the risk of all cause patien

33 anion gap and prehospital admission standard anion gap is associated with all cause mortality in the

34 The serum anion gap is decreased in hyperchloremic (HCl) acidosis

35 es following multivariable adjustment: delta anion gap <0 mEq/L odds ratio 0.75 (95% confidence inter

36 Acidemia and increased anion gap, markers of systemic hypoperfusion, were also

37 accumulation, as reflected by a hyperosmolar anion gap metabolic acidosis, was observed in critically

38 18 mEq/L did not materially change the delta anion gap-mortality association.

39 albumin concentrations as follows: adjusted anion gap = observed anion gap + 0.25 x ([normal albumin

40 ith a significant risk gradient across delta anion gap quartiles following multivariable adjustment:

41 , survival, laboratory profiling, calculated anion gap, strong ion difference, and strong ion gap.

42 ing on plasma bicarbonate concentration and "anion gap," the other on "base excess," with a third met

43 levated serum glutamic pyruvic transaminase, anion gap, thrombin-antithrombin complex, IL-6, IL-8, an

44 This adjustment returns the anion gap to the familiar scale of values that apply whe

45 ecrease in serum albumin caused the observed anion gap to underestimate the total concentration of ga

46 Delta anion gap was a particularly strong predictor of 30-day

47 When the anion gap was computed with HCO3 (AGHCO3 = Na + K - Cl -

48 When the anion gap was computed with total CO2 content (AGTCO2 =