ライフサイエンスコーパス: anorexigen

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1 y arterial hypertension (PAH) arose owing to anorexigens, acting as indirect serotinergic agonists, c

2 Interestingly, the anorexigens also caused pulmonary arterial hypertension

3 e; or as a result of the use of fenfluramine anorexigens, amphetamines, or cocaine.

4 550 patients with idiopathic, heritable, and anorexigen-associated PAH from eight cohorts that had be

5 ients with untreated PAH (8 idiopathic and 2 anorexigen-associated PAH) and 12 control subjects.

6 s of Patient 1 and the six of Patient 2 with anorexigen-associated PH exhibited a monoclonal expansio

7 For the current study, we asked whether anorexigen-associated PH is characterized by monoclonal

8 ls of plexiform lesions of two patients with anorexigen-associated PH.

9 tients (93% idiopathic, 5% heritable, and 2% anorexigen-associated pulmonary arterial hypertension) w

10 Exclusion of the two anorexigen cases did not alter these results.

11 A melanocortin receptor agonist, a potent anorexigen, decreases AMPK activity in PVH, whereas agou

12 combinant frog leptin (rxLeptin) is a potent anorexigen in frogs, as it is in mammals, but this respo

13 activated by orexigens and inhibited by the anorexigen leptin.

14 The anorexigens may accelerate the growth of pulmonary endot

15 Anorexigens such as aminorex fumarate and dexfenfluramin

16 Anorexigens that modulate serotonin release and reuptake

17 Use of anorexigen therapy is associated with valvular abnormali

18 scular signs and symptoms were similar among anorexigen-treated and untreated subjects.

19 k (RR) of AR were significantly increased in anorexigen-treated patients and were 8.9% in the dexfenf

20 e, 4.0%; and untreated, 8.4%); and following anorexigen treatment were uncommon (dexfenfluramine, 2.3

21 mine group, while the untreated group had no anorexigen use during the previous 5 years.

22 , when adjusted for the median start date of anorexigen use).

23 the scleroderma spectrum of diseases or with anorexigen use.

24 sers, reminiscent of that induced by certain anorexigens used for weight reduction.

25 Anorexigens were shown to enhance hypoxic pulmonary vaso

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