ライフサイエンスコーパス: antagonize

1 oreover, our findings support a strategy for antagonizing 5-HT1A autoreceptors for treating cocaine a

2 5'-Methyl 25 and ethyl 26 esters potently antagonized 5HT2Rs with moderate selectivity in comparis

3 us, a plant pathogen effector has evolved to antagonize a host autophagy cargo receptor to counteract

4 ant forms of AmOmpA and ApOmpA competitively antagonize A. marginale infection of host cells, but a m

5 mechanism: ARF physically interacts with and antagonizes activation by acetylation of the master redo

6 ells rounding in PC3 cells, indicating EphA2-antagonizing activity of EM2.

7 terminant that independently evolved SERINC5-antagonizing activity.

8 units of the myosin phosphatase complex that antagonizes actomyosin contractility, as proteins safegu

9 woman are exposed to caffeine, which acts to antagonize adenosine action.

10 , not by repressing AG transcription, but by antagonizing AG activity in the center of the flower.

11 ces dsRNA in response to IFN, potentially to antagonize antiviral defenses.

12 All viruses must antagonize antiviral signaling events for survival.

13 encing, the mechanisms by which flaviviruses antagonize antiviral small RNA pathways in disease vecto

14 switches tumor metabolism toward glycolysis, antagonizes apoptosis and autophagy, dampens oxidative s

15 om increased srx-44 expression in ASJ, which antagonizes ASI and ADL.

16 and competes with Stat3 for p300 binding to antagonize astrogliogenesis.

17 nd a specific ATPase subunit of the base and antagonize base-CP interaction.

18 ) principal cells are capable of driving and antagonizing behaviors of opposing valence.

19 that RD26 can interact with BES1 protein and antagonize BES1 transcriptional activity on BR-regulated

20 study, we show that part of the challenge in antagonizing beta-catenin is caused by its dual function

21 Wnts can also suppress lateral cell fates by antagonizing Bmp4 expression.

22 nodeficiency virus type 1 Vpu protein, which antagonizes both virion entrapment and the activation of

23 effective in early disease, while drugs that antagonize BS toxicity, such as ursodeoxycholic acid and

24 data suggest that maintaining the ability to antagonize BST-2 is of functional relevance not only to

25 We show that BtrA binds and antagonizes BtrS, a BvgAS-regulated extracytoplasmic fun

26 interleukin-6 production, each of which was antagonized by a specific A2bR antagonist (PSB-603).

27 ata suggest that viral RCs can be marked and antagonized by a universal immune defense mechanism targ

28 The activity of the E3 ligase, SMURF2, is antagonized by an intramolecular, autoinhibitory interac

29 citation, but were mimicked by muscarine and antagonized by atropine, indicating that it requires ACh

30 ial pathogen/host interaction is efficiently antagonized by biaryl alpha-d-mannopyranosides.

31 tivation, migration, and adhesion, a process antagonized by BTK and PI3K inhibitors.

32 model of acute inflammatory pain, which was antagonized by CB1 and CB2 receptor antagonists/inverse

33 roteinase 2 (MMP2) and MMP9 activity that is antagonized by Chrdl1.

34 However, the actions of MAST3 are antagonized by dopamine and cAMP-regulated signaling lea

35 integrin alphaIIbbeta3 activation, a process antagonized by endothelial prostacyclin.

36 increased glycolytic activity that was also antagonized by FP7.

37 phorylation by cyclin-dependent kinase 5 and antagonized by Fyn phosphorylation.

38 and cell-to-cell spread of bacteria but are antagonized by IpaH9.8, a bacterial ubiquitin ligase sec

39 As maximal expression of miR-216b is antagonized by Ire1, miR-216b accumulation reflects the

40 t Abeta at the BBB, in a process that can be antagonized by its putative natural ligand, desmosterol

41 ew methylation site of the HIF1alpha protein antagonized by LSD1 and the interplay between HIF1alpha

42 d SERINC5 restricts HIV-1 infectivity and is antagonized by Nef and analyzed both virions and produce

43 as antiviral activity, which is specifically antagonized by NS5B.

44 in the presence of PknA, and this effect was antagonized by PknA-K42N, a kinase-dead variant.

45 This is antagonized by S1PR4 signaling, thus decreasing TLR-indu

46 Wnt-Frizzled interactions can be antagonized by secreted Frizzled-related proteins (SFRPs

47 urthermore, we show that NmFic activation is antagonized by tetramerization.

48 ut, after the reproductive transition, it is antagonized by the MADS box transcription factor SQUAMOS

49 al promoter site, but this activation can be antagonized by the regulator CysB.

50 ability and cytoskeletal reorganization were antagonized by the selective TRPV4 blocker HC 067047.

51 to fuse with target cells, an effect that is antagonized by the viral Nef protein.

52 nts that maintain the HIV reservoir are also antagonized by venetoclax.

53 oradrenaline was reproduced by clonidine and antagonized by yohimbine, consistent with contribution o

54 -nuclear Cat L-CUX1 drives EMT, which can be antagonized by Z-FY-CHO.

55 tress were given soluble beta-glucans, which antagonize C-type lectin domain family 7 member A (CLEC7

56 Fhod antagonizes capping protein but dissociates from barbed

57 n, KDM3A induces ovarian cancer growth while antagonizing cellular senescence by repressing the expre

58 zed NAP family protein in fission yeast that antagonizes CENP-A loading at both centromeric and non-c

59 in and represses gene expression, and it can antagonize centromere function or CENP-A assembly.

60 s, we found that the nanobodies were able to antagonize chemerin-induced intracellular calcium increa

61 DNA repair-independent function of BRCA1 in antagonizing COBRA1-dependent transcription programme du

62 We determined whether antagonizing CXCR4 with POL5551 disrupts anti-vascular e

63 does not directly target VEGF receptors but antagonizes cysteinyl leukotriene receptors 1 and 2 (Cys

64 n during bacterial infection, NleB1/NleB(CR) antagonizes death receptor-induced apoptosis of infected

65 To achieve this, antibodies are used to antagonize differentiation, survival and polarization si

66 te the positive symptoms of schizophrenia by antagonizing dopamine D2 receptors expressed by striatal

67 We further confirm that IRAB-B antagonizes downstream signaling and metabolic function.

68 Finally, the Siah2 E3 ubiquitin ligase antagonizes drebrin function, suggesting a model for con

69 lly induced in healthy human eSCs in situ by antagonizing E-cadherin, combined with transforming grow

70 Moreover, these two pathways antagonize each other and thus regulate the directional

71 charide (LPS) receptors CD14 and TLR4, which antagonize each other by affecting epithelial cell proli

72 roposes that pain- and touch-sensing neurons antagonize each other through spinal cord dorsal horn (D

73 Surprisingly, these two species antagonize each other's virulence in both nematode infec

74 ated to its editing activity, as well as the antagonizing effect of RBP binding on miRNA repression.

75 from LUBAC-mediated restriction through the antagonizing effects of the effector E3 ligase IpaH1.4 o

76 -CHO may be an important therapeutic tool to antagonize EMT and cancer progression.

77 ed the cellular pool of available let-7, and antagonizing endogenous let-7 triggered cell proliferati

78 rachidonic acid 15-lipoxygenase (ALOX15) are antagonizing enzymes in the metabolism of hydroperoxy li

79 TOT classically antagonizes estradiol (E2) -dependent breast cancer cell

80 Neither antagonizing extracellular CA nor blocking loading of pr

81 ap (Cg), a zinc-finger transcription factor, antagonizes Eya-So function in the SMW.

82 is in irt1 plants, indicating that manganese antagonized Fe mainly at the level of transport.

83 a cells from Abeta-mediated cytotoxicity and antagonizes fibrillation and cytotoxicity pathways of se

84 les remain stationary with a small amount of antagonizing force generated.

85 subpopulations in a heterogeneous mixture by antagonizing formation of the chromatin modifier PRC2 an

86 directly by occupying the Erag enhancer and antagonizing Foxo1 binding to a consensus forkhead site

87 etic evidence that in Escherichia coli, FtsA antagonizes FtsZ protofilament bundling in vivo.

88 but lack the menin-binding ability, thereby antagonizing full-length SON function in transcriptional

89 is mediated by multiple core components with antagonizing functions.

90 the feoABC operon by ArcA and FNR partially antagonized Fur-mediated repression of feoABC under anae

91 molecule inhibitors act at this interface to antagonize fusion activation.

92 ) bound the cannabinoid receptor 1 (CB1) and antagonized G protein coupling.

93 ns of the PI3K gene PIK3CA was attenuated by antagonizing GLI1 and PI3K.

94 Mechanistically, LPA antagonized glucagon-mediated inhibition of STAT3, a tra

95 ) regulates hepatocyte glucose production by antagonizing glucagon-induced expression of the gluconeo

96 antiporter promotes antioxidant defence, it antagonizes glutamine metabolism and restricts nutrient

97 elor and ticagrelor, previously suggested to antagonize GPR17.

98 ampers neutrophil expansion and migration by antagonizing granulocyte colony-stimulating factor (G-CS

99 19 glycosylation suggests that glycosylation antagonizes GSK3beta binding.

100 te activation of GSK3beta in beta cells, and antagonizing GSK3beta (SB216763; IC50 = 34.3 nM) rescued

101 We show that although PK11195 antagonizes hCAR in HepG2 cells, it induces the expressi

102 h as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP)

103 on, we provide a new mechanism by which AMPK antagonizes hepatic glucagon signalling via phosphorylat

104 We found that Nt-acetylation of histone H4 antagonizes histone H4 serine 1 phosphorylation (H4S1ph)

105 ple of an HIV-1 group O Vpu that efficiently antagonizes human tetherin and suggest that counteractio

106 et that can be selectively inhibited without antagonizing human BET function.

107 Administering miR-223 agomir in vivo antagonized hypoxia-induced increase in pulmonary artery

108 Simvastatin antagonizes I domain binding to the complement fragments

109 as a switch for beta1 integrin activation by antagonizing ICAP1-mediated inhibition of integrin activ

110 lation of the IFN response allows viruses to antagonize IFN at multiple levels.

111 er assay suggesting that all tPs function to antagonize IFN induction in muscle cells.

112 The mechanism(s) by which ZIKV antagonizes IFN signaling is unknown.

113 hat the nonstructural protein 1 (NS1) of WNV antagonizes IFN-beta production, most likely through sup

114 Antagonizing IL-4 prevented mucosal barrier disruption a

115 While bNAbs potently antagonize infection with cell-free virus, inhibition of

116 inhibitors of IL-34, may thus contribute to antagonize inflammation and bone erosions in RA.

117 a multifunctional cytokine produced by APCs, antagonizes inflammation by affecting conventional dendr

118 confines KCC2 to the plasma membrane, while antagonizing inhibition reduces KCC2 surface expression

119 Zeb2 antagonizes inhibitory effectors including Notch and Sox

120 ecting the maximum agonist effect (Emax) but antagonized insurmountably (suppressed agonist Emax) in

121 mall intestine and has evolved strategies to antagonize interferon and NF-kappaB signalling, raising

122 otease (PLpro) that possesses the ability to antagonize interferon immune pathways through the remova

123 he selective pressures exerted on viruses to antagonize it.IMPORTANCE Viruses in the family Coronavir

124 and the 19-residue conotoxin alpha-GID that antagonizes it.

125 s employed by a plant commensal bacterium to antagonize its competitors and broadly implicates NAD(P)

126 indicating that ADAR2 stabilizes Ctn RNA by antagonizing its degradation by PARN and HuR.

127 asites, thus confirming that Wnt5a signaling antagonizes L. donovani infection.

128 Based on these results, we propose that FtsA antagonizes lateral interactions between FtsZ protofilam

129 e chick) allows sensory organ segregation by antagonizing lateral induction and promoting commitment

130 How Rivipansel antagonizes ligand recognition by E-selectin and blocks

131 Most examined gamma1 mutant subunits antagonized mallotoxin's channel-activating effect in a

132 ntional management has relied on agents that antagonize mediators released by mast cells, inhibit med

133 atement by mGluR2/3 blockade was reversed by antagonizing mGluR5, but reinstated sucrose seeking in t

134 ed by CML cells and/or the microenvironment, antagonize MHC-II expression, highlighting the potential

135 ut these effects diminish or disappear after antagonizing miR-9 (TuD).

136 reveal a novel mechanism by which CAMK2gamma antagonizes mTORC1 activation during hepatocarcinogenesi

137 riggers a physiological stress response that antagonizes mTORC1, a multisubunit host kinase that cont

138 th CARD (ARC) is a cell death inhibitor that antagonizes multiple death programs.

139 sults introduce mechanisms of persistence in antagonized mutualistic communities that were previously

140 Intriguingly, TuMV seems to antagonize NBR1-dependent autophagy during infection by

141 ptide Y pathway acts together with SRB-13 to antagonize negative effects of the GCY-35 hyperoxia sens

142 lesions, they remained puzzling; because K1 antagonizes NF-kappaB in vitro, antiviral gene expressio

143 KCNK3 antagonizes norepinephrine-induced membrane depolarizati

144 nd propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute

145 local anesthetic drug lidocaine was shown to antagonize NsVBa without affecting channel gating.

146 elements in AXIN1's second intron, and RUNX1 antagonizes oestrogen-mediated AXIN1 suppression.

147 PTEN is a PIP3 phosphatase that antagonizes oncogenic PI3-kinase signalling.

148 In addition, ascorbic acid antagonized only the BDE-99-dependent loss of human, not

149 s, and many viruses have evolved measures to antagonize or even exploit autophagy mechanisms for the

150 ch receptor family may induce responses that antagonize or synergize with the activities of another f

151 y 3 independent interactions responsible for antagonizing or potentiating antibiotic activity against

152 ion of the SA-dependent IRE1-bZIP60 arm that antagonizes organ growth; CPR5 also favors growth in str

153 our, gallic acid, was previously reported to antagonize other amyloids and to exert anti-inflammatory

154 The MDM2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent f

155 y, thus providing another mechanism how Plk1 antagonizes p53 during DNA damage response.

156 importance, the mechanism by which Hedgehog antagonizes Patched has remained unknown.

157 nd ameliorates autoimmune uveitis in mice by antagonizing pathogenic Th17 responses.

158 gs reveal a strategy beyond immunotherapy to antagonize patients' antibody effects.

159 n of IL2 and STAT5 genes, which are known to antagonize peripheral Tfh cell function.

160 The inherent difficulties of antagonizing physiological effects of drugs in the centr

161 se-II-associated proteins like PAF1 and RTF1 antagonize PIWI-directed silencing.

162 ion with PKR ablated the ability of pTRS1 to antagonize PKR activation by dsRNA.

163 The HCMV pTRS1 and pIRS1 proteins antagonize PKR to promote HCMV protein synthesis and rep

164 Tubacin, an inhibitor of HDAC6, antagonized PlGF-mediated repression of DNM3os/pre-miR-1

165 Induction of de novo superenhancers antagonizes Polycomb repression and superimposes aberran

166 at is required for osteoblastogenesis, while antagonizing PPARgamma-mediated adipogenesis.

167 synMuvB class transcription factor known to antagonize PRC2 activity.

168 A2 expression can compensate for SMARCA4 and antagonize PRC2 targets.

169 ne and local anti-inflammatory mediator that antagonizes pro-inflammatory actions of FGF23 and TGF-be

170 kpoint inhibitors (including antibodies that antagonize programmed cell death protein 1 [PD-1]) have

171 trarenal FoxP3(+) Treg accumulation, thereby antagonizing proinflammatory CD11b(+) DCs.

172 type compound, compound 1 (AGN 211377), that antagonizes prostaglandin D2 receptors (DPs) DP1 (49) an

173 AGN 211377 antagonizes prostanoid prostaglandin D2 (DP)1, DP2, pros

174 hibited the PU.1/DNA complex in vitro, fully antagonized PU.1-dependent transactivation in vivo.

175 By antagonizing RAD51 at forks, RADX allows cells to mainta

176 9, modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the confo

177 heir regulation by having individual members antagonize rather than cooperate with each other.

178 etion of ROS1, suggesting that ROS1 strongly antagonizes RdDM at these loci.

179 In addition, we show that ROS1 also antagonizes RdDM-independent DNA methylation at some loc

180 RhoD recruits Pak6 to the plasma membrane to antagonize RhoC signaling during cell contraction and bl

181 odiesterase (PDE) that cleaves 2-5A, thereby antagonizing RNase L activation.

182 ns and animals, encode 2',5'-PDEs capable of antagonizing RNase L.

183 P28 and bZIP60 in plant UPR, and identify an antagonizing role of BI1 in the pro-adaptive signaling m

184 in physiological conditions and in stress by antagonizing SA-dependent growth inhibition through UPR

185 ated whether chronic caffeine administration antagonizes salt sensitive hypertension by promoting uri

186 y promotes proliferation of immature SCs and antagonizes SC differentiation during nerve development.

187 Cell, Ghisi et al. show that high ID2 levels antagonize self-renewal and promote differentiation of l

188 4 R expression levels in aged/diseased hCPCs antagonizes senescence and improves functional responses

189 important human pathogens that consistently antagonize signaling related to type I interferon respon

190 turn recruits a deubiquitinase UBPY/USP8 to antagonize Smo ubiquitination and degradation, leading t

191 o Carotid endothelial denudation showed that antagonizing smooth muscle cell USP20 activity increased

192 acylhydrazones as privileged structures for antagonizing STAT SH2 domains, and demonstrates that apo

193 The PRRSV-mediated antagonizing STAT3 could lead to suppression of a broad

194 of miR-191, and dysregulated IRS1 expression antagonizes STAT5 activation.

195 ng bacterial infection of macrophages, RECON antagonized STING activation by acting as a molecular si

196 ely to have a wider metabolic niche than the antagonized strain: that is, larger metabolic networks a

197 Intriguingly, for each interaction the antagonizing strain was more likely to have a wider meta

198 Treatment with all-trans retinoic acid antagonizes stress-induced activation of dHSCs by restri

199 that the inner nuclear membrane protein Sun1 antagonizes Sun2 LINC complexes and inhibits RhoA activa

200 show that a peptidyl-prolyl isomerase PINN-1 antagonizes SYDN-1 in the spatiotemporal control of neur

201 ned by Id2, a transcriptional regulator that antagonizes T and B cell-specific gene expression progra

202 1 shuttles between the cytoplasm and nucleus antagonizing TAZ/YAP by distinct mechanisms in the two c

203 Mechanistically, GRM3 antagonizes TGFbeta-mediated activation of protein kinas

204 genesis pERK initially facilitates and later antagonizes TGFbeta-mediated cell cycle arrest, yet rema

205 ng evidence indicate that PTPs do not always antagonize the activity of PTKs in regulating tyrosine p

206 Accordingly, strategies to antagonize the antiapoptotic Bcl-2 proteins have largely

207 JUNV's ability to antagonize the antiviral activity of PKR appears to be c

208 e viral TRS1 and IRS1 proteins were found to antagonize the antiviral kinase PKR outside the context

209 the ability of CYP17 inhibitors to directly antagonize the AR may contribute to their clinical effic

210 male that suppress her sexual receptivity or antagonize the behavior of competing males; both are usu

211 The MARCKS peptides antagonize the binding of factor Xa to phosphatidylserin

212 interacted with central domain of FUBP1 and antagonize the binding of FBP-interacting repressor to F

213 the development of sepals and petals and to antagonize the C-function in the outer floral whorls.

214 miR-214 and miR-148b have been proposed to antagonize the effects of each other in enabling or bloc

215 totic gene BCL2 Finally, mir-200 was able to antagonize the epithelial-mesenchymal transition (EMT) d

216 nstructural proteins encoded by flaviviruses antagonize the host IFN response via various means in or

217 olyprotein to facilitate RNA replication and antagonize the host innate immune response.

218 Nef) in HIV-1 infectivity, being required to antagonize the inhibitory activity of Serine incorporato

219 e hypothesis that CoV ExoN also functions to antagonize the innate immune response.

220 kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or

221 These viruses cannot antagonize the mammalian interferon (IFN) response mount

222 tural and synthetic progestins were found to antagonize the mitogenic effects of estrogens.

223 However, the inability of ZIKV to antagonize the mouse IFN response renders the virus high

224 e 2',5'-phosphodiesterases (2',5'-PDEs) that antagonize the OAS-RNase L pathway, and we report here t

225 respiratory syndrome-associated coronavirus antagonize the oligoadenylate-RNase L (OAS-RNase L) path

226 tudy examined the ability of GIP(3-30)NH2 to antagonize the physiological actions of GIP in glucose m

227 al assays show that FHR-A and FHR-B proteins antagonize the protective function of FH in sheep erythr

228 Although AH-7614 did not antagonize the second long-chain free fatty acid recepto

229 the previously described ability of Cur1 to antagonize the yeast prion [URE3], it enhances propagati

230 induced the migration of L1.2-CCR2 cells but antagonized the chemokine-induced migration of L1.2-CCR5

231 l progenitor cell state; on many genes, KLF7 antagonized the corneal differentiation-promoting KLF4.

232 Additionally, testosterone antagonized the effect of pregnenolone sulfate.

233 Our assay also showed that desmosterol antagonized the export of Abeta, presumably as both bind

234 RK-33 antagonized the increase in oxygen consumption and ATP p

235 a variety of cell-based reporter assays; and antagonized the prosurvival action of BAFF on primary mo

236 Our results indicate that FP7 antagonized the secretion of proinflammatory cytokines (

237 STAT5 antagonized the transcription factors NF-kappaB and IKAR

238 Finally, we found that TOR antagonizes the action of the classic defense hormones s

239 FliW antagonizes the CsrA-dependent repression of translation

240 Surprisingly, Mte1 antagonizes the D-loop-dissociative activity of Mph1-MHF

241 These results suggest that Prok2 antagonizes the direct wake-promoting effect of light in

242 The host antiviral protein APOBEC3G (A3G) antagonizes the early steps of HIV-1 infection through t

243 ot inhibit NF-kappaB signaling even while it antagonizes the entrapment of virus-like particles.

244 In conclusion, GRbeta antagonizes the GC-induced signaling during fasting via

245 and the binding of the NS5A protein to GBP1 antagonizes the GTPase activity and thus the antiviral e

246 isease in humans, from dengue virus to ZIKV, antagonizes the host type I interferon (IFN-I) response

247 hat the nonstructural protein 1 (NS1) of WNV antagonizes the induction of interferon beta (IFN-beta)

248 to stimulate insulin secretion and, instead, antagonizes the insulinotropic effect of Oxo-M and CCh-i

249 Gabapentin antagonizes the interaction of thrombospondins (TSPs) wi

250 Here, we discovered that PRRSV antagonizes the JAK/STAT3 signaling by inducing degradat

251 We show that one Sox2-replacing antibody antagonizes the membrane-associated protein Basp1, there

252 Ectopic expression of either IRF4 or MYC antagonizes the phenotypic and transcriptional effects o

253 of its putative binding partner dendrin and antagonizes the pro-survival signaling of the downstream

254 s a local inhibitor of bone acquisition that antagonizes the profound osteoanabolic capacity of activ

255 -Csm3 by the replisome and that this complex antagonizes the Rrm3 helicase, thereby promoting PFA, by

256 On the contrary, we find that atpenin A5 antagonizes the stabilization of HIF-1alpha and reduces

257 These results indicate that PRRSV antagonizes the STAT3 signaling by accelerating STAT3 de

258 he Ebola virus envelope glycoprotein (GP1,2) antagonizes the trapping of newly formed virions at the

259 eplication because replication-competent HRV antagonizes the type III IFN response at pre- and posttr

260 s the effects of glial KCC-3 on AFD shape by antagonizing the actin regulator WSP-1/NWASP.

261 The strategy of antagonizing the activity of broadly acting terminal sel

262 to reactivate the p53 tumor suppressor while antagonizing the anti-apoptotic function of Bcl-2 is hig

263 cine in these models was further improved by antagonizing the anti-oxidant response.

264 these studies demonstrate that specifically antagonizing the CBP/catenin interaction with ICG-001 ca

265 IF1alpha/VEGF-mediated tumor angiogenesis by antagonizing the crosstalk between PTMs involving HIF1al

266 Antagonizing the expression of miR-15a and miR-16, enhan

267 blocked the differentiation of TH17 cells by antagonizing the function of transcription factor RORgam

268 ssory protein that enhances virus release by antagonizing the host restriction factor BST-2.

269 t, as well as previously identified roles in antagonizing the innate immune defenses of the cell and

270 ing constitutive apoptosis, and importantly, antagonizing the normal pro-apoptotic effect of GCS.

271 k protection complex is essential for PFA by antagonizing the Rrm3 helicase that displaces nonhistone

272 res with the base-excision repair pathway by antagonizing the uracil DNA glycosylase (Ung2) enzyme.

273 binant human TSP-1 can bind BMP-2 and -4 and antagonize their effects on C3H10T1/2 cells.

274 at JMJD1A knockdown in prostate cancer cells antagonizes their proliferation and survival.

275 of targeting the stability of tankyrases by antagonizing their interaction with USP25 to modulate th

276 that natural thyroid hormone derivatives may antagonize these actions.

277 Antagonizing these adaptive responses could improve drug

278 evelopment, and type B EAE is ameliorated by antagonizing these receptors.

279 Therefore, FP7 can antagonize TLR4 activation in vitro and protect mice fro

280 symptoms, as does treatment with drugs that antagonize TLR4-NF-kappaB signaling or the SPAK-NKCC1 co

281 to Tumor Necrosis Factor (TNF) receptors and antagonizing TNFalpha.

282 o the multikinase inhibitor dasatinib, which antagonizes TNK2 kinase activity, as well as novel TNK2

283 e respiratory epithelium with rhinovirus can antagonize tolerance to inhaled antigen through combined

284 larity, we hypothesized that resveratrol may antagonize topo II by a similar mechanism.

285 Hence, our data define that YOD1 antagonizes TRAF6/p62-dependent IL-1 signaling to NF-kap

286 activation indicating that pharmacologically antagonizing TRPM3 may be a useful analgesic strategy.

287 adipocytes (browning), whereas streptomycin antagonized TRPM8-mediated calcium entry, downregulated

288 To genetically antagonize tubular epithelial NF-kappaB activity, we gen

289 In addition, TGF-beta1 and BMP-2 antagonized tumor necrosis factor alpha-induced IL-34 ge

290 to act as a deubiquitinase and deISGylase to antagonize type I interferon (IFN-I) immune pathways.

291 sing dependent upon cGAS-STING.IMPORTANCE By antagonizing type I interferon production and action, ma

292 iangiogenic VEGFxxxb isoforms are thought to antagonize VEGFxxxa isoforms and decrease activation of

293 promote EMT via CUX1 and that this could be antagonized with the Cat L-specific inhibitor Z-FY-CHO.

294 AD-CT makes the FH2 domain more efficient in antagonizing with capping protein.

295 ases and consequent stabilization of Axin to antagonize Wnt signaling.

296 e, whereas high expression levels of sFRP1/5 antagonize Wnt/JNK signaling.

297 WNT974 efficiently antagonized Wnt signaling in human CML CD34(+) cells, an

298 Antagonizing Wnt10b signaling with DKK1 or Wnt10b antibo

299 or suppressor gene which acts by selectively antagonizing YAP-dependent tumor growth.

300 t also operates in the embryo and may act to antagonize zygotically activated transposons.