ライフサイエンスコーパス: antagonizing

1 ecular target of lurasidone, possibility via antagonizing 5-HT(7) receptors, which is consistent with

2 oreover, our findings support a strategy for antagonizing 5-HT1A autoreceptors for treating cocaine a

3 First, Snail promotes cell survival by antagonizing a p53-dependent death pathway because coinc

4 ing that these two residues are critical for antagonizing a putative host restriction factor which ha

5 to mediate actin binding and assembly while antagonizing actin-capping proteins.

6 ane domain to the HIV-1(NL4-3) Vpu conferred antagonizing activity against macaque BST-2.

7 ells rounding in PC3 cells, indicating EphA2-antagonizing activity of EM2.

8 ther than ventral territory, and yet the BMP-antagonizing activity of gremlin is required for normal

9 terminant that independently evolved SERINC5-antagonizing activity.

10 , not by repressing AG transcription, but by antagonizing AG activity in the center of the flower.

11 In contrast, deleting Rb1 in the antagonizing AGRP/NPY neurons shows no effects.

12 chromatin at the onset of meiosis I, thereby antagonizing AIR-2 and cooperating with the cohesin comp

13 Thus, antagonizing AMIGO3 rather than LINGO-1 immediately afte

14 nstrate that all Nef proteins are capable of antagonizing ancestral Cercopithecini tetherin.

15 To assess the functional role of CD36 in antagonizing angiogenic response in Met homozygosity at

16 This well characterized antagonizing antibody to the GIPr will be useful as a to

17 Here we describe the generation of an antagonizing antibody to the GIPr, using phage and ribos

18 rophage migration inhibitory factor (MIF) in antagonizing antimelanoma immune responses reveal that m

19 Moreover, antagonizing BAFF altered the phenotype of alveolar and

20 Antagonizing BAFF in CS-exposed mice attenuates pulmonar

21 Antagonizing BCL-2 with venetoclax derepresses this anta

22 14, which resides in the BH4 domain, thereby antagonizing Bcl-xL-Bax binding.

23 ) principal cells are capable of driving and antagonizing behaviors of opposing valence.

24 study, we show that part of the challenge in antagonizing beta-catenin is caused by its dual function

25 resses differentiation inhibitory signals by antagonizing BMP receptor-activated Smad activity while

26 Wnts can also suppress lateral cell fates by antagonizing Bmp4 expression.

27 ehaved as a dominant-negative FZD5 receptor, antagonizing both canonical and non-canonical WNT signal

28 olates, such as Vpu of HIV-1DH12, capable of antagonizing both human and rhesus BST-2.

29 ARC possesses the unusual property of antagonizing both the extrinsic (death receptor) and int

30 together with Swi5-Sfr1 play a major role in antagonizing both the FANCM-family DNA helicase/transloc

31 lly, by altering protein degradation, and by antagonizing BR-induced changes in microtubule organizat

32 ments, we show here that SerRS intervenes by antagonizing c-Myc, the major transcription factor promo

33 Thus, selectively antagonizing Ca(V)1.3 L-type calcium channels could prov

34 ious substrates, regulates CRL activation by antagonizing CAND1 binding.

35 ole of Sulfs in myoblast fusion by promoting antagonizing canonical Wnt signaling activities against

36 gonists at two distinct opioid receptors and antagonizing CCK receptors in the CNS.

37 cells, an effect that could be inhibited by antagonizing CCL22-driven chemotaxis.

38 n, KDM3A induces ovarian cancer growth while antagonizing cellular senescence by repressing the expre

39 DNA repair-independent function of BRCA1 in antagonizing COBRA1-dependent transcription programme du

40 ficacy of a new cocaine vaccine (dAd5GNE) in antagonizing cocaine addiction-related behaviors in rats

41 hosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channel.

42 filaments for binding to cortactin, thereby antagonizing cortactin activity.

43 We determined whether antagonizing CXCR4 with POL5551 disrupts anti-vascular e

44 utcome of antipsychotic treatments, commonly antagonizing D2 dopamine receptors (D2Rs), on cognitive

45 eficial effects in vivo while simultaneously antagonizing deleterious ones.

46 72 by augmenting phosphorylation by LKB1 and antagonizing dephosphorylation by PP2C.

47 repression of proliferation-terminating (MYC-antagonizing) differentiation genes in cancer cells.

48 toma tumor suppressor, is also important for antagonizing DNA sensing.

49 s unblocked by disabling the innate response antagonizing domains (IRADs) in EBOV VP35 and VP24 by th

50 te the positive symptoms of schizophrenia by antagonizing dopamine D2 receptors expressed by striatal

51 lly induced in healthy human eSCs in situ by antagonizing E-cadherin, combined with transforming grow

52 dependent cell cycle arrest in G1 and G2, by antagonizing early or late p53-mediated responses, respe

53 action suggested the specificity of the mDia-antagonizing effect of INF2 in maintaining the lamellipo

54 ated to its editing activity, as well as the antagonizing effect of RBP binding on miRNA repression.

55 of UVRAG with RUBICON, thereby enhancing the antagonizing effect of RUBICON on UVRAG-mediated autopha

56 from LUBAC-mediated restriction through the antagonizing effects of the effector E3 ligase IpaH1.4 o

57 riments demonstrate that BS69 promotes IR by antagonizing EFTUD2 through physical interactions.

58 is responsible for the factor's activity in antagonizing eIF1 binding to the PIC.

59 ion increases epithelial Na(+) absorption by antagonizing ENaC ubiquitination.

60 ctivation of PP2A (here accomplished through antagonizing endogenous inhibitors) could be a novel ant

61 ed the cellular pool of available let-7, and antagonizing endogenous let-7 triggered cell proliferati

62 modulatory nucleic acids act by agonizing or antagonizing endosomal toll-like receptors (TLR3, TLR7/8

63 rachidonic acid 15-lipoxygenase (ALOX15) are antagonizing enzymes in the metabolism of hydroperoxy li

64 anism during cardiac stress, for example, by antagonizing excessive beta-AR drive.

65 Neither antagonizing extracellular CA nor blocking loading of pr

66 levels of soluble VEGF receptor 1 (sFlt), an antagonizing factor to VEGF.

67 binding to sialic acid, prevent FH19-20 from antagonizing FH function on cells.

68 This leads to PA antagonizing FKBP38 inhibition of mTORC1 kinase activity

69 les remain stationary with a small amount of antagonizing force generated.

70 How these apparently antagonizing forces interact in the coinfected host is p

71 subpopulations in a heterogeneous mixture by antagonizing formation of the chromatin modifier PRC2 an

72 he IL-7 receptor alpha-chain (IL-7Ralpha) by antagonizing Foxo1 and negatively regulated signaling by

73 directly by occupying the Erag enhancer and antagonizing Foxo1 binding to a consensus forkhead site

74 hort Ase1 isoforms stabilizes the spindle by antagonizing full-length Ase1.

75 but lack the menin-binding ability, thereby antagonizing full-length SON function in transcriptional

76 is mediated by multiple core components with antagonizing functions.

77 ns of the PI3K gene PIK3CA was attenuated by antagonizing GLI1 and PI3K.

78 ) regulates hepatocyte glucose production by antagonizing glucagon-induced expression of the gluconeo

79 Antagonizing glycine uptake and its mitochondrial biosyn

80 ampers neutrophil expansion and migration by antagonizing granulocyte colony-stimulating factor (G-CS

81 target gene network and test strategies for antagonizing growth of this tumor.

82 te activation of GSK3beta in beta cells, and antagonizing GSK3beta (SB216763; IC50 = 34.3 nM) rescued

83 ility, with the facilitative sites primarily antagonizing H3K27me3 and H3K9me3 deposition.

84 1000-fold less potent than fursultiamine in antagonizing hepcidin.

85 tes the D/V patterning of the spinal cord by antagonizing Hh signaling.

86 ate that H4K20me3 invokes gene repression by antagonizing hMOF-mediated H4K16Ac and suggest that over

87 egument protein that plays critical roles in antagonizing host antiviral responses.

88 et that can be selectively inhibited without antagonizing human BET function.

89 as a switch for beta1 integrin activation by antagonizing ICAP1 (Integrin Cytoplasmic Associated Prot

90 as a switch for beta1 integrin activation by antagonizing ICAP1-mediated inhibition of integrin activ

91 Antagonizing IL-1beta with Anakinra, a rheumatoid arthri

92 Antagonizing IL-4 prevented mucosal barrier disruption a

93 a previously unappreciated role of RasGAP in antagonizing indirect activation of PDGFRbeta, define th

94 confines KCC2 to the plasma membrane, while antagonizing inhibition reduces KCC2 surface expression

95 noninfectious particles and are incapable of antagonizing interferon (IFN) effectively.

96 is critical for maintaining PMN survival by antagonizing intracellular CG activity.

97 promoted antibody affinity maturation while antagonizing IRF4-driven differentiation of plasmablasts

98 aA) expression under anaerobic conditions by antagonizing IscR binding at P(hyaA), since IscR repress

99 B55beta promotes cyclin E1 overexpression by antagonizing its degradation and its inhibition could re

100 indicating that ADAR2 stabilizes Ctn RNA by antagonizing its degradation by PARN and HuR.

101 iptional repressor in this context, and that antagonizing its function in the diencephalon attenuates

102 Activation of p53 tumor suppressor by antagonizing its negative regulator murine double minute

103 itro and in vivo by binding beta-catenin and antagonizing its nuclear localization.

104 ERK induces ind by antagonizing its repression by Capicua (Cic), a transcri

105 ith phosphorylation to stabilize Smoothened, antagonizing its ubiquitination and subsequent degradati

106 MAPK overexpression or removal of CDK-5, an antagonizing kinase.

107 e chick) allows sensory organ segregation by antagonizing lateral induction and promoting commitment

108 nfection, as well as for the design of drugs antagonizing leukocidin toxicity.

109 montelukast, a marketed anti-asthmatic drug antagonizing leukotriene receptors, reduces neuroinflamm

110 e a novel avenue to bone anabolic therapy by antagonizing LRP4 sclerostin facilitator function.

111 harzianum, that act as biocontrol agents by antagonizing M. roreri.

112 Thus, strategies focused on antagonizing MCL-1 function and expression would be pred

113 regulator of MT stability that functions by antagonizing mDia1 activity toward actin filaments and s

114 Antagonizing MDM2 and MDMX to activate the tumor suppres

115 In addition to antagonizing Mdm2, Strap facilitates the recruitment of

116 by coculture with bone marrow stromal cells antagonizing MEK-ERK dephosphorylation.

117 nhibits zinc-dependent induction of Dnmt1 by antagonizing metal-responsive transcription factor-1 (MT

118 ependent methylation favors proliferation by antagonizing methylation by PRMT1.

119 atement by mGluR2/3 blockade was reversed by antagonizing mGluR5, but reinstated sucrose seeking in t

120 lung inflammation, and this was restored by antagonizing miR-1.

121 Notably, antagonizing miR-10b action enhanced NKG2D-mediated kill

122 Conversely, antagonizing miR-146a (but not miR-155) heightened the s

123 Both antagonizing miR-155 to induce Bim and proteasome inhibi

124 Conversely, antagonizing miR-182 enhances BRCA1 levels and induces r

125 Antagonizing miR-182 enhances BRCA1 protein levels and p

126 Conversely, antagonizing miR-200 and miR-183-96-182 cluster miRNAs i

127 Antagonizing miR-33a function in GICs reduced self-renew

128 Recent studies in mice suggest that antagonizing miR-33a may be an effective strategy for ra

129 ut these effects diminish or disappear after antagonizing miR-9 (TuD).

130 intrinsically to promote GSC self-renewal by antagonizing MOF function.

131 -rich proteoglycan, inhibits tumor growth by antagonizing multiple receptor tyrosine kinases includin

132 ress tumorigenesis by directly targeting and antagonizing multiple receptor tyrosine kinases, such as

133 Antagonizing myelin-derived inhibitors signaling with Ng

134 key survival factor in the heart by directly antagonizing necroptosis, which is critical for the main

135 These findings also suggest that drugs antagonizing NET activity, used for the treatment of hyp

136 s adverse consequences in endothelial cells, antagonizing NO production and reparative mechanisms.

137 n conjunction to promote ISC self-renewal by antagonizing Notch signaling.

138 nd propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute

139 y 3 independent interactions responsible for antagonizing or potentiating antibiotic activity against

140 Indeed, its role is context dependent, antagonizing or promoting disease depending on the circu

141 modifications of histones are implicated in antagonizing or recruiting the de novo DNA methylation c

142 ntration-specific responses by sequestering, antagonizing, or activating regulatory proteins in respo

143 hypothalamic oxytocin neurons and centrally antagonizing oxytocin in mice are similarly obesogenic.

144 lator of the p53 tumor suppressor protein by antagonizing p53 transactivation activity and targeting

145 1) promotes recovery in G2-arrested cells by antagonizing p53, it is dispensable for recovery from a

146 te duplication created a novel gene function-antagonizing parental SRGAP2 function-immediately "at bi

147 nd ameliorates autoimmune uveitis in mice by antagonizing pathogenic Th17 responses.

148 age targeted in ABC-DLBCL transformation--by antagonizing pathways distinctive of GCB-DLBCL, includin

149 of atypical long-range projections, whereas antagonizing Pax6 function in the thalamus disrupts cTh

150 RK activation, which occurs independently of antagonizing phosphatase activity.

151 is mediated, in part, by Clp1/Cdc14, a Cdk1-antagonizing phosphatase, which reverses Cdk1 phosphoryl

152 The inherent difficulties of antagonizing physiological effects of drugs in the centr

153 mour suppressor, thought to primarily act by antagonizing PI3-kinase signalling.

154 s their transcriptional activation activity, antagonizing PIF-induced growth.

155 This discovery suggests that antagonizing PKP2 may be a new therapeutic opportunity t

156 This is accomplished in part by antagonizing plasticity-promoting signaling pathways act

157 phatase also controls mitosis, apparently by antagonizing polo-like kinase 1 (PLK1).

158 d suggest that both activities play roles in antagonizing Polycomb silencing, stimulating enhancer ac

159 tant, suggesting that H3K4me1 is involved in antagonizing Polycomb silencing.

160 ulation of H3K27ac play an important role in antagonizing Polycomb silencing.

161 cuate nucleus (ARC) in hypothalamus contains antagonizing POMC and AGRP/NPY neurons for negative and

162 choline, either lowering cholinergic tone or antagonizing postsynaptic M(1) muscarinic receptors norm

163 nd dilatation but also provide evidence that antagonizing PPARbeta/delta represents an important stra

164 at is required for osteoblastogenesis, while antagonizing PPARgamma-mediated adipogenesis.

165 R3 signaling, suggesting that this occurs by antagonizing pro-apoptotic signals induced by TNF.

166 trarenal FoxP3(+) Treg accumulation, thereby antagonizing proinflammatory CD11b(+) DCs.

167 yet recognized increased expression of genes antagonizing proinflammatory signaling and inflammatory

168 By antagonizing RAD51 at forks, RADX allows cells to mainta

169 9, modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the confo

170 specifically within Ras-mutant cell lines by antagonizing release of negative feedback signalling, de

171 ies have also found that ISG15 is capable of antagonizing replication of some viruses in tissue cultu

172 We now report the identification of a Rho-antagonizing RNA element (RARE) that hinders Rho-depende

173 the histone octamer, but its contribution to antagonizing RNA polymerase II (Pol II) access and trans

174 odiesterase (PDE) that cleaves 2-5A, thereby antagonizing RNase L activation.

175 ns and animals, encode 2',5'-PDEs capable of antagonizing RNase L.

176 o reach and cross the spinal cord midline by antagonizing Robo1/2-mediated repulsion from midline-exp

177 quitin ligase for histone H2A, indicating an antagonizing role of BAP1 against Ring1B-Bmi1.

178 P28 and bZIP60 in plant UPR, and identify an antagonizing role of BI1 in the pro-adaptive signaling m

179 Antagonizing RORalpha activity may be a therapeutic stra

180 presses auxin signalling, preventing it from antagonizing SA signalling.

181 in physiological conditions and in stress by antagonizing SA-dependent growth inhibition through UPR

182 istone deacetylase 1 (HDAC1) recruitment and antagonizing Slug E-box binding.

183 o Carotid endothelial denudation showed that antagonizing smooth muscle cell USP20 activity increased

184 aintain totipotency and germline identity by antagonizing somatic fate.

185 inding activity directly but by functionally antagonizing Ssn6-Tup1.

186 acylhydrazones as privileged structures for antagonizing STAT SH2 domains, and demonstrates that apo

187 sive effects of p28/p40 derived in part from antagonizing STAT1 and STAT3 pathways induced by IL-27 a

188 The PRRSV-mediated antagonizing STAT3 could lead to suppression of a broad

189 25-HC acts by antagonizing sterol response element-binding protein (SR

190 Intriguingly, for each interaction the antagonizing strain was more likely to have a wider meta

191 striatal output that is acutely corrected by antagonizing striatal mGluR5.

192 d and it will be of interest to test whether antagonizing suppressive functions of CLL MDSCs could re

193 ing in human cells by post-transcriptionally antagonizing TAZ but not YAP, two downstream effectors o

194 1 shuttles between the cytoplasm and nucleus antagonizing TAZ/YAP by distinct mechanisms in the two c

195 cification in the second heart precursors by antagonizing Tbx1/10-mediated inhibition of GATAa and ac

196 s the effects of glial KCC-3 on AFD shape by antagonizing the actin regulator WSP-1/NWASP.

197 e TOP2A 3'UTR repressed TOP2A translation by antagonizing the action of HuR.

198 the activation of inflammatory responses by antagonizing the activation of the NF-kappaB canonical p

199 CR) and MAPK-Erk signaling by binding to and antagonizing the activities of RAF1, BRAF, and spleen ty

200 BH3 mimetic drugs induce cell death by antagonizing the activity of antiapoptotic Bcl-2 family

201 The strategy of antagonizing the activity of broadly acting terminal sel

202 racts with the Notch signaling pathway by it antagonizing the activity of E(spl)-C proteins.

203 or gene expression independently of Notch by antagonizing the activity of hypoxia-inducible factors (

204 27 trimethylation of histone 3 (H3K27me3) by antagonizing the activity of PRC2.

205 untranslated RNAs, termed CsrB and CsrC, in antagonizing the activity of the RNA binding protein Csr

206 fies and patterns the hindbrain territory by antagonizing the activity of the spinal cord specificati

207 Some of these pesticides are also capable of antagonizing the androgen receptor.

208 to reactivate the p53 tumor suppressor while antagonizing the anti-apoptotic function of Bcl-2 is hig

209 cine in these models was further improved by antagonizing the anti-oxidant response.

210 ed NK cell proliferation during infection by antagonizing the anti-proliferative factor Blimp-1 (Prdm

211 Antagonizing the ATP-dependent P2X7 receptor pathway of

212 hibits efficacy comparable with SR141716A in antagonizing the basal G protein coupling activity of CB

213 5-A10, which interacts with heparan sulfate, antagonizing the binding of the virus to cells.

214 these studies demonstrate that specifically antagonizing the CBP/catenin interaction with ICG-001 ca

215 lizes acetylated cohesin complexes on DNA by antagonizing the cohesin release factor Wings-apart like

216 IF1alpha/VEGF-mediated tumor angiogenesis by antagonizing the crosstalk between PTMs involving HIF1al

217 ugh transcriptional positive feedback, while antagonizing the developmental networks of competing lin

218 this restriction was partially surmounted by antagonizing the DNA-dependent protein kinase (DNA-PK),

219 of hemogenic vascular niche specification by antagonizing the dorsal-ventral regulatory limits of VEG

220 2 transcription in myeloid progenitor cells, antagonizing the effect of HoxA10 on Triad1 expression.

221 Antagonizing the expression of miR-15a and miR-16, enhan

222 These results indicate that antagonizing the function of cIAPs may promote the clear

223 blocked the differentiation of TH17 cells by antagonizing the function of transcription factor RORgam

224 romoted the generation of plasma cells while antagonizing the GC fate.

225 ood restriction causes growth attenuation by antagonizing the GH stimulatory effects on chondrogenesi

226 cs for diabetes, one focus of study has been antagonizing the ghrelin system in order to improve gluc

227 trated that SUFU stabilizes Glis3 in part by antagonizing the Glis3 association with a Cullin 3-based

228 reversion to a less aggressive phenotype by antagonizing the growth effect of 17beta-estradiol.

229 Recently, anti-inflammatory effects in AD by antagonizing the histamine (H)-4 receptor have also been

230 viral proteins/genetic elements involved in antagonizing the host immune response.

231 ssory protein that enhances virus release by antagonizing the host restriction factor BST-2.

232 st shutoff by IBV plays an important role in antagonizing the host's innate immune response.

233 Antagonizing the human M3 muscarinic receptor (hM3R) ove

234 ), whereas PGRP-LCy may have a minor role in antagonizing the immune response.

235 t, as well as previously identified roles in antagonizing the innate immune defenses of the cell and

236 level of INS-7 from URX disrupts learning by antagonizing the insulin receptor-like homolog DAF-2 in

237 hich the modulation of TRPV1 is inhibited by antagonizing the interaction between TRPV1 and A kinase

238 umor suppressive function in the pancreas by antagonizing the metaplastic conversion of acinar cells

239 DOCK7 exerts its effects by antagonizing the microtubule growth-promoting function o

240 at SCCRO3 functions as a tumor suppressor by antagonizing the neddylation activity of SCCRO.

241 PSD-95 in the early-adolescent PFC, without antagonizing the NMDA receptor.

242 ing constitutive apoptosis, and importantly, antagonizing the normal pro-apoptotic effect of GCS.

243 Antagonizing the NPY1 receptors by intracerebroventricul

244 AIP inhibits IRF7 function by antagonizing the nuclear localization of IRF7.

245 oidance responses in Arabidopsis thaliana by antagonizing the phytohormones auxin and gibberellin.

246 Sema-PlxnD1 signaling exerts this effect by antagonizing the proangiogenic activity of vascular endo

247 es mesenchymal invasion, through binding and antagonizing the RAC1-GAP protein ARHGAP24.

248 ting that IdeR induces bfrB transcription by antagonizing the repressor activity of Lsr2.

249 Compounds antagonizing the retinol-dependent interaction of retino

250 k protection complex is essential for PFA by antagonizing the Rrm3 helicase that displaces nonhistone

251 suggest that USP16 has an important role in antagonizing the self-renewal and/or senescence pathways

252 Our findings support the hypothesis that antagonizing the signaling of GHRH in T1D may improve GL

253 e were significantly reduced by functionally antagonizing the smooth muscle contraction with isoprote

254 Oleoyl CoA potently inhibits Kir2.1 by antagonizing the specific requirement for PIP(2), and EP

255 determination and promotes proliferation by antagonizing the TGF-beta ligand myostatin.

256 sus the potentially negative consequences of antagonizing the therapeutic efficacy of antidepressant

257 specificity of these inhibitory compounds in antagonizing the transcriptional function of nuclear bet

258 These results suggest that antagonizing the TRPV1-AKAP79 interaction will be a usef

259 put chemical screen, we found that molecules antagonizing the TRPVs (transient receptor potential van

260 lopment of lethal cancer at least in part by antagonizing the tumor-suppressive functions of the SWI/

261 res with the base-excision repair pathway by antagonizing the uracil DNA glycosylase (Ung2) enzyme.

262 omib) classes was blocked by IB-MECA without antagonizing their antitumor effect.

263 of targeting the stability of tankyrases by antagonizing their interaction with USP25 to modulate th

264 ediated adhesion of CLL cells to hyaluronan, antagonizing their motile behavior.

265 ress, and mitochondrial dysfunction, thereby antagonizing thermogenic activation of sWAT.

266 Antagonizing these adaptive responses could improve drug

267 lood-induced cartilage damage, the effect of antagonizing these cytokines was examined in human in vi

268 evelopment, and type B EAE is ameliorated by antagonizing these receptors.

269 -induced NGC during budding and suggest that antagonizing this curvature is a viable anti-influenza s

270 Because tumor IDO inhibits CD19-CARTs, antagonizing this enzyme may benefit CD19-CART therapy.

271 taining protein alpha (SGTA) in specifically antagonizing this process.

272 us and tumor Ag-specific CD8(+) T cells, and antagonizing Tim-3 helps restore function of CD8(+) T ce

273 raction of TLR3ecd with dsRNA, thus directly antagonizing TLR3 signaling through inhibition of SU for

274 Therapeutically antagonizing TNF (etanercept) or S1P (JTE013) signaling

275 proliferation, we determined the outcome of antagonizing TNF-alpha in CCR5(-/)(-) mice infected with

276 to Tumor Necrosis Factor (TNF) receptors and antagonizing TNFalpha.

277 We identify the apoptosis-antagonizing transcription factor (AATF) as a novel nucl

278 The activity of antagonizing transcription factors represents a mechanis

279 n of alternative transcriptional programs by antagonizing transcription factors.

280 tate expression of these cell cycle genes by antagonizing transcriptional repression mediated by p53.

281 activation indicating that pharmacologically antagonizing TRPM3 may be a useful analgesic strategy.

282 overactivity can be partially normalized by antagonizing TRPv1 receptors in skeletal muscle.

283 eported to activate mTORC1 by binding to and antagonizing tuberous sclerosis complex protein 2 (TSC2)

284 ecognized role for migratory CD103(+) DCs in antagonizing type 2 immune responses.

285 rse mammalian poxviruses were all capable of antagonizing type I IFN-induced antiviral activities aga

286 sing dependent upon cGAS-STING.IMPORTANCE By antagonizing type I interferon production and action, ma

287 bilizing SMN and the SMN complex, likely via antagonizing Ub-dependent SMN degradation.

288 nic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor receptor

289 acenta causes pre-eclampsia-like features by antagonizing vascular endothelial growth factor signalin

290 Antagonizing VE-cadherin widened cell-cell junctions and

291 duction of runx1+ HSPCs in the AGM region by antagonizing VEGF signaling and subsequent assignment of

292 By antagonizing Vegfa activity in explants, EMT was rescued

293 Further, antagonizing vlPAG TLR4 dose dependently prevented the d

294 at Scc1 sumoylation by Mms21 promotes SCR by antagonizing Wapl at a step after cohesin loading at DSB

295 AD-CT makes the FH2 domain more efficient in antagonizing with capping protein.

296 enin polyubiquitination and impaired FAF1 in antagonizing Wnt/beta-catenin signaling.

297 Antagonizing Wnt10b signaling with DKK1 or Wnt10b antibo

298 cating that Eco1p performs a function beyond antagonizing Wpl1p.

299 molar affinities and are highly effective in antagonizing XIAP in cell-free functional assays.

300 or suppressor gene which acts by selectively antagonizing YAP-dependent tumor growth.