ライフサイエンスコーパス: anterior limb

1 have ectopic Shh and Ptch1 expression in the anterior limb.

2 Hand2 likely mediates Gli3 repression in the anterior limb.

3 ssively by power-strokes of each of the more anterior limbs.

4 ns in TBX5, a related and linked gene, cause anterior limb abnormalities in Holt-Oram syndrome.

5 ctyly phenotype with loss of digits from the anterior limb, although the development of more proximal

6 bers descend in the internal capsule (SMA in anterior limb and genu; M1 in posterior limb) and traver

7 ing activity, leading to derepression of the anterior limb and induction of polarizing zone marker ge

8 n mouse led to ectopic Shh expression in the anterior limb bud and a preaxial polydactyly (PPD) skele

9 nd-independent Shh signaling, was induced in anterior limb bud cells resulting in extra digits.

10 duced extra, sometimes multiple digits, from anterior limb bud demonstrating the negative role in Shh

11 is required to inhibit Shh expression in the anterior limb bud mesenchyme.

12 nges in the regulation of development of the anterior limb bud resulting in ectopic expression of sig

13 Ectopic Ihh expression in the distal and anterior limb bud results in the ectopic activation of s

14 The polydactyly was preceded by unexpected anterior limb bud transcription of Shh, so one function

15 al cells, including mesenchymal cells in the anterior limb bud, and mice homozygous for targeted disr

16 topic sonic hedgehog (Shh) expression in the anterior limb bud.

17 F signaling to inhibit Shh expression in the anterior limb bud.

18 of ptc1 is to repress Shh expression in the anterior limb bud.

19 In addition, anterior limb buds show aberrant Gli3 processing, consis

20 function abrogates ectopic Shh expression in anterior limb buds, limits overexpression in the zone of

21 ons in the Shh limb enhancer lead to similar anterior limb defects, highlight the importance of Shh r

22 , results in a severe truncation of proximal-anterior limb elements.

23 the pathways were widespread, involving the anterior limb, genu and posterior limb with the M3 proje

24 ough the middle and posterior portion of the anterior limb (ICa).

25 actyly exhibit ectopic Shh expression at the anterior limb margin.

26 Beads soaked in Shh-N do not induce Shh in anterior limb mesenchyme ruling out direct propagation o

27 ch are known repressors of Shh expression in anterior limb mesenchyme, strongly enhances the anterior

28 Msx-2 during normal limb development in the anterior limb mesoderm, the posterior necrotic zone, and

29 dulating the level of Gli3 processing in the anterior limb mesoderm.

30 integrity in the fibers that are part of the anterior limb of internal capsule (ALIC) in MDD and diab

31 Lower fractional anisotropy in the anterior limb of internal capsule at discharge and in ge

32 ubcortical, 188 x 10(-5) mm(2)/sec at birth; anterior limb of internal capsule, 130 x 10(-5) mm(2)/se

33 and/or maintain continued development of the anterior limb of the developing heart.

34 (-0.01; p = .02) of the corpus callosum and anterior limb of the internal capsule (-0.02; p =.01) at

35 around the nucleus accumbens (P = .03), and anterior limb of the internal capsule (P = .02).

36 study of DBS targeting the ventral striatum/anterior limb of the internal capsule (VS/ALIC) in 10 pa

37 uced fractional anisotropy (FA) in the right anterior limb of the internal capsule and right uncinate

38 In addition, reduced FA in anterior limb of the internal capsule correlated signifi

39 nteers revealed that fiber tracts within the anterior limb of the internal capsule have a significant

40 ateral lesions in the ventral portion of the anterior limb of the internal capsule over a 20-year per

41 primates form a well defined and topographic anterior limb of the internal capsule, the specific loca

42 re also associated with abnormalities in the anterior limb of the internal capsule, the white matter

43 mental manipulations of the striatum and the anterior limb of the internal capsule.

44 mbic connection following the fornix and the anterior limb of the internal capsule.

45 side irradiated at the ventral border of the anterior limb of the internal capsule.

46 be viewed as the rat homolog of the primate anterior limb of the internal capsule.

47 , a small region of increased atrophy in the anterior limb of the left internal capsule adjacent to t

48 to sham deep brain stimulation (DBS) in the anterior limb of the ventral capsule/ventral striatum (V

49 esults explain why GLI3 is required only for anterior limb patterning and why GLI2 can compensate for

50 nd Shh gene dosage improves the integrity of anterior limb structures, validating the importance of t

51 he involvement of inhibitory pathways in the anterior limb that prevent secondary polarizing zone for