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1 neurons are guided: one dorsoventral and one anteroposterior.
2  superior anteroposterior, 0.60 for inferior anteroposterior, 0.50 for superior craniocaudal, and 0.6
3 rate, with kappa values of 0.54 for superior anteroposterior, 0.60 for inferior anteroposterior, 0.50
4 ircular with decreased ratio of mediolateral/anteroposterior (1.11+/-0.09 versus 1.32+/-0.09, P<0.000
5  with distinct subregions varying across the anteroposterior (A-P) axis.
6 ion differs across the wing and is primarily anteroposterior (A-P) in the anterior and proximodistal
7  D-V pathfinding but to strongly perturb the anteroposterior (A-P) pathfinding process by which moton
8 mbryo by specifying segmental boundaries and anteroposterior (A-P) segmental polarity.
9                      In phase 1, the initial anteroposterior (a-p) subdivision of the head mesoderm i
10 at will become the VD axon extends along the anteroposterior (A/P) axis in the ventral nerve cord (VN
11 f the fluoroscopy unit used and their supine anteroposterior abdominal diameter (group 1, 8.0-8.5-cm
12 y results in greater changes in lateral than anteroposterior airway diameter and that these effects a
13  in cross-sectional airway area, lateral and anteroposterior airway diameters, and tissue strain (str
14 lateral symmetry by establishing rudimentary anteroposterior and dorsoventral (DV) axes.
15    The functions of wg varied along both the anteroposterior and dorsoventral axes of the embryo.
16             It defines development along the anteroposterior and dorsoventral axes of the vertebrate
17 y networks pattern the neural tube along its anteroposterior and dorsoventral axes.
18 sitional information from genes important in anteroposterior and dorsoventral axis formation, includi
19         These observations indicate that the anteroposterior and dorsoventral distribution of rods is
20 nclude: (i) malformations secondary to early anteroposterior and dorsoventral patterning defects, or
21 n explain gene expression patterns with both anteroposterior and dorsoventral polarities.
22 urs along three cardinal axes-proximodistal, anteroposterior and dorsoventral-that are established vi
23                    Diagnosis is confirmed on anteroposterior and frog-leg lateral radiographs of both
24 th suggestive groin symptoms should have hip anteroposterior and frog-leg lateral radiographs to rule
25 ral annular dimensions (circumference, area, anteroposterior and intercommissural diameters, height,
26 he effective diameter, the average of aortic anteroposterior and lateral diameters, was independently
27 hen asked about knee pain and weight-bearing anteroposterior and lateral knee radiographs were obtain
28 Subjects were examined acutely with standard anteroposterior and lateral radiography, nuclear medicin
29 neural plate with a coarse pattern along its anteroposterior and mediolateral axes, this basis is pro
30 ed between temporal and condylar regions and anteroposterior and mediolateral directions.
31 sion cell movements are coordinated with the anteroposterior and mediolateral embryonic axes.
32 aintain gene expression boundaries along the anteroposterior and mediolateral neural axes that are im
33 ery was typically oval shaped with decreased anteroposterior and normal lateral diameters.
34                                              Anteroposterior and septal/lateral scar localization was
35           Radiographic films (weight-bearing anteroposterior and skyline views) were read for Kellgre
36                                      Length, anteroposterior and superoinferior diameters, attenuatio
37 rom the dorsoventral axis, but also from the anteroposterior and terminal patterning systems in the b
38 t9a are required for palate extension in the anteroposterior and transverse axes, respectively.
39 nalyses included measurements of the maximum anteroposterior and transverse dimensions of the anterio
40               Annular area and mediolateral, anteroposterior, and high (superior)-low (inferior) dist
41 he left-right (LR) body axis relative to the anteroposterior (AP) and dorsoventral (DV) axes is centr
42              In Drosophila melanogaster, the anteroposterior (AP) and dorsoventral (DV) axes of the o
43  asymmetric flow with previously established anteroposterior (AP) and dorsoventral (DV) axes remain p
44 rsors into distinct subpopulations along the anteroposterior (AP) and dorsoventral (DV) axes.
45                  Two organizers that control anteroposterior (AP) and dorsoventral (DV) development a
46 ing and growth along the proximodistal (PD), anteroposterior (AP) and dorsoventral (DV) limb axes.
47 evelop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions,
48    SSDE conversion factors were derived from anteroposterior (AP) and lateral dimensions measured on
49                 In the first, weight-bearing anteroposterior (AP) and lateral knee radiographs were o
50 entify the center of pressure (COP), and its anteroposterior (AP) and mediolateral (ML) displacements
51  to previously defined dorsoventral (DV) and anteroposterior (AP) axes.
52 re, we report that Sqd is also essential for anteroposterior (AP) axis formation.
53                         Specification of the anteroposterior (AP) axis in Drosophila oocytes requires
54 in the developing secondary palate along the anteroposterior (AP) axis in mice.
55  found previously that cells elongate in the anteroposterior (AP) axis in the extending germband, sug
56                     The establishment of the anteroposterior (AP) axis is a crucial step during anima
57 eport that DV patterning along the zebrafish anteroposterior (AP) axis is temporally coordinated with
58  and partially overlapping domains along the anteroposterior (AP) axis of the early embryo.
59                 Patterning of the vertebrate anteroposterior (AP) axis proceeds temporally from anter
60 ch the embryo uncouples its midline from the anteroposterior (AP) axis.
61 iosis and the establishment of the embryonic anteroposterior (AP) axis.
62  for any of these cells to migrate along the anteroposterior (AP) axis.
63 terneurons form contiguous columns along the anteroposterior (AP) axis.
64 rentially to cells near its source along the anteroposterior (AP) boundary of the wing disc.
65 itionally, squamous morphogenesis shifts the anteroposterior (AP) compartment boundary in the peripod
66 nd region extends approximately 10 mm in the anteroposterior (AP) dimension, primarily within the upp
67 ee radiograph (anatomic(PA) axis), and 3) an anteroposterior (AP) full-limb radiograph (anatomic(AP)
68  one localizer radiographic examination with anteroposterior (AP) or posteroanterior (PA) projections
69 subjects, a skyline view of each knee and an anteroposterior (AP) or posteroanterior (PA) radiograph
70 ress these issues, we first investigated the anteroposterior (AP) origin of the IP complex by fate-ma
71 ere, we investigated potential regulators of anteroposterior (AP) pattern during fin regeneration in
72 h conserved roles in deuterostome ectodermal anteroposterior (AP) patterning in developing embryos, t
73                                              Anteroposterior (AP) patterning of the developing CNS is
74                                       During anteroposterior (AP) patterning of the developing hindbr
75 en is required for the dorsoventral (DV) and anteroposterior (AP) patterning of the retina.
76                         The establishment of anteroposterior (AP) polarity in the early mouse epiblas
77 co-evolve with the mechanisms that establish anteroposterior (AP) polarity of the embryo.
78                                              Anteroposterior (AP) rotation of the hindbrain prior to
79 s, and includes Dpp signaling components and anteroposterior (AP) segmentation determinants.
80 ar to be key players in the specification of anteroposterior asymmetries in the zebrafish ear.
81 d gnathostomes already had well-defined otic anteroposterior asymmetries.
82  that Rho kinase 2b (Rock2b) is required for anteroposterior asymmetry and fluid flow in KV, but it r
83 ell shape changes control the development of anteroposterior asymmetry in KV, which is necessary to g
84 rms initial symmetry in KV architecture into anteroposterior asymmetry.
85 mb bud patterning along the proximodistal or anteroposterior axes functioning through induction of Me
86 etent to be patterned along dorsoventral and anteroposterior axes.
87 circular canals and ampullae - by conferring anteroposterior axial information to these structures.
88       Rotating rhombomeres 5 and 6 along the anteroposterior axis also impacts cochlear duct morphoge
89 tly associated, such as specification of the anteroposterior axis and anterior neural development, or
90 ry in the epiblast is regionalized along the anteroposterior axis as in lower vertebrates.
91  ablation of Aurora A properly establish the anteroposterior axis but fail to progress through gastru
92 orphogen controls cell fate along 70% of the anteroposterior axis but is translated from mRNA localiz
93  Blimp1 is required for the establishment of anteroposterior axis formation and the formation of head
94 s establish that Eomes is a key regulator of anteroposterior axis formation, EMT and definitive endod
95 cing atRAL levels and is required for proper anteroposterior axis formation, neuroectoderm patterning
96                         The formation of the anteroposterior axis in mice requires a Wnt3-dependent s
97 ry, we identify new muscle domains along the anteroposterior axis in the zebrafish that are defined b
98 genes specify appendage identities along the anteroposterior axis independently of Tc-hth/Tc-exd and
99 ific factors in response to dorsoventral and anteroposterior axis information.
100         In Xenopus, the establishment of the anteroposterior axis involves two key signalling pathway
101 , when differential Hox expression along the anteroposterior axis is being established, we found conc
102        Together, these results show that the anteroposterior axis is correctly positioned by the acti
103                   The Caenorhabditis elegans anteroposterior axis is established in response to ferti
104                    Specification of the otic anteroposterior axis is one of the earliest patterning e
105 ans, Hox genes determine cell fate along the anteroposterior axis of embryos and are implicated in dr
106 eneity was observed between groups and along anteroposterior axis of healthy hippocampus in both grou
107 nases are asymmetrically localized along the anteroposterior axis of newly fertilized C. elegans embr
108 lished in the one-cell embryo determines the anteroposterior axis of the developing animal and is ess
109 ntial nuclear organisation of Hoxb along the anteroposterior axis of the developing neural tube is co
110 ern of expression with that of Mn1 along the anteroposterior axis of the developing palatal shelves a
111 A exhibits differential expression along the anteroposterior axis of the developing secondary palate,
112 les and cellular hairs (trichomes) along the anteroposterior axis of the Drosophila thorax (notum).
113  develop at two specific positions along the anteroposterior axis of the embryo, whereas other region
114 f polarising activity, which establishes the anteroposterior axis of the limb bud and maintains proli
115 he long-distance movement of ShhN across the anteroposterior axis of the limb bud.
116 role for the ExE in the specification of the anteroposterior axis of the mouse embryo.
117 rhythmic movements are distributed along the anteroposterior axis of the nervous system.
118 ed pattern of neurons is specified along the anteroposterior axis of the vertebrate spinal cord by in
119 mediated activation of Vent2 and Cdx4 during anteroposterior axis specification.
120 like gene are expressed in domains along the anteroposterior axis that reset to new positions during
121 nin specifies the posterior character of the anteroposterior axis throughout the Bilateria and specif
122 al germ layer becomes regionalized along its anteroposterior axis to give rise to a variety of organs
123 dition, disrupts the proper alignment of the anteroposterior axis with the shape of the embryo and th
124 erning of the pharyngeal apparatus along the anteroposterior axis, and local regulation of retinoic a
125 ertebrate body is its segmentation along the anteroposterior axis, as illustrated by the repetition o
126  otic vesicle is highly asymmetric about the anteroposterior axis, both morphologically and molecular
127 n signaling to polarize the termini of their anteroposterior axis, but little is known about how rege
128 By contrast, Bozozok can rescue the complete anteroposterior axis, but not notochord, in embryos bloc
129 eotides resulted in a phenotype of shortened anteroposterior axis, reduced head structure, and pertur
130 ertebrates is relatively symmetric about the anteroposterior axis, with only two semicircular canals
131  new gut branches are added along the entire anteroposterior axis.
132 ange in signaling by the notochord along the anteroposterior axis.
133 ical neurons or white matter cells along the anteroposterior axis.
134 ng the complete pattern of digits across the anteroposterior axis.
135 ogical and molecular heterogeneity along the anteroposterior axis.
136 rently depending on their location along the anteroposterior axis.
137 arget area because of guidance errors in the anteroposterior axis.
138  as somite pairs sequentially form along the anteroposterior axis.
139 lling polarizes neural progenitors along the anteroposterior axis.
140 f cilia, depending on the location along the anteroposterior axis.
141 t is the establishment of polarity along the anteroposterior axis.
142 that of visceral muscle precursors along the anteroposterior axis.
143 enesis is differentially regulated along the anteroposterior axis.
144 ting the existing proximodistal axis into an anteroposterior axis.
145 or a functional division primarily along the anteroposterior axis.
146 spatially varying tissue mechanics along the anteroposterior axis.
147  gradient and initiates patterning along the anteroposterior axis.
148  of the conceptus or failure to elongate the anteroposterior axis.
149 he dorsal adult muscles are polarised in the anteroposterior axis: we disprove the hypothesis that mu
150                           A large decline in anteroposterior bending strength of the femur and tibia
151 s of cell intercalations are altered and the anteroposterior bias of radial intercalations is lost.
152 process that allows for divergence along the anteroposterior body axis in arthropods.
153 nal position of the QR descendants along the anteroposterior body axis, is mediated through a cell-au
154 er of Nap1 mutants is the duplication of the anteroposterior body axis.
155  is the primary driving force elongating the anteroposterior body axis.
156  new somites are permitted to form along the anteroposterior body axis.
157 dth, distance from the lateral border of the anteroposterior bone crest to the sinus wall, and height
158 s and two experienced operators catheterized anteroposterior (celiac, superior mesenteric, and inferi
159                                              Anteroposterior cell migration and patterning in C. eleg
160 s during double support and they had reduced anteroposterior CM-CP divergence (P < 0.001) during doub
161 hese findings suggest that there is a direct anteroposterior connection between the retrolental and p
162 ed greater concordance with reference to the anteroposterior coordinate (P<0.001).
163 strocaudal coordinates; the mean lateral and anteroposterior coordinates of the directly localized PP
164 at cross-cord projections participate in the anteroposterior coupling.
165    Some axon growth cones also respond to an anteroposterior cue, following a segmented pathway, and
166 hyseal form, dental morphology and size, and anteroposterior dental proportions, as well as aspects o
167                   The horizontal (width) and anteroposterior (depth) dimensions of the bursa were rec
168 arizing activity is the major determinant of anteroposterior development of the amniote limb.
169 the anterior and middle thirds of the tibial anteroposterior diameter and was not age dependent.
170 ves caused greater increases in lateral than anteroposterior diameter in all three regions with diffe
171 highest rated quantitative criterion was the anteroposterior diameter of the osseous canal, with a me
172 All recorded data were stratified by patient anteroposterior diameter to determine effects of patient
173 l subjects were recorded, and transverse and anteroposterior diameters were measured.
174 sulted in extensive polydactyly with loss of anteroposterior digit patterning and shortening of the p
175 s the SI enhancement measured in the largest anteroposterior dimension in the axial plane 1 minute af
176 esulted in greater decreases in lateral than anteroposterior dimension in the caudal oropharynx and v
177 nd increasing annular area, primarily in the anteroposterior dimension.
178 ral directions were higher than those in the anteroposterior direction (P <.01 for all).
179 vely) and for failure load and anisotropy in anteroposterior direction (r = -0.65) were found.
180 ntal group, the largest RMSDs were 1.1 mm in anteroposterior direction and 2.6 degrees in pitch orien
181 es were compressed to varying degrees in the anteroposterior direction to create 3 datasets: thin-sli
182  technology suggest that axons project in an anteroposterior direction within the Probst bundle.
183 iate regions of the disc when sheared in the anteroposterior direction, both shear and compressive mo
184 al-orbitofrontal regions and propagate in an anteroposterior direction.
185 and the posterior superior attachment in the anteroposterior direction.
186 ssure (CP) dynamics (in the mediolateral and anteroposterior directions), and foot clearance paramete
187 evaluated for tilt angle in mediolateral and anteroposterior directions, CT appearance of tip embeddi
188 ins, disrupted KV cell shape changes and the anteroposterior distribution of KV cilia.
189 otile behaviors of cells with respect to the anteroposterior embryonic axis.
190 al) and epichordal (caudal) neuroepithelium, anteroposterior encroachment of alar lunatic fringe (L-f
191 egurgitation annulus, which, despite similar anteroposterior enlargement, is narrower and essentially
192 ns of horizontal EOMs have minimal effect on anteroposterior EOM pulley positions.
193 ng Shh signalling in early wing buds reduced anteroposterior expansion, and posterior digits were los
194 ting proliferation also irreversibly reduced anteroposterior expansion, but instead anterior digits w
195 ck of rugae is also associated with retarded anteroposterior extension of the hard palate and precoci
196                                          The anteroposterior extent of the damage to Meyer's loop was
197 pa Values were 0.43 for determining superior anteroposterior extent, 0.47 for determining superior cr
198 caudal extent, 0.57 for determining inferior anteroposterior extent, and 0.48 for determining inferio
199 nitiation and suggests that a pre-pattern of anteroposterior fate specification is already present in
200  dispersed within a coarse somatotopographic anteroposterior (foot to face) gradient in the dentate a
201             The embryonic tectum displays an anteroposterior gradient in development and produces the
202 tages regrew at the same rate but with fewer anteroposterior guidance errors, and were more likely to
203 ggest that a pre-existing genetic system for anteroposterior head patterning was co-opted for pattern
204 the selective lamina I input to VMpo and the anteroposterior (head to foot) topography.
205                                       In the anteroposterior (horizontal) plane, chemical connectivit
206  the specification of neurons with different anteroposterior identities.
207 s a molecular switch to specify and maintain anteroposterior identity during regeneration and homeost
208 e insight into the mechanisms that establish anteroposterior identity in the developing mammalian bra
209                Furthermore, we show that the anteroposterior identity of tail bud progenitor cells ca
210 etermined in highly standardized, semiflexed anteroposterior images.
211 o (dorsoventral axis in amphibians and fish, anteroposterior in amniotes).
212 agittal and reformatted axial-oblique views, anteroposterior including three conjugates of pelvic inl
213 rticipants underwent standard weight-bearing anteroposterior knee radiography and posteroanterior han
214 t knee pain and had bilateral weight-bearing anteroposterior knee radiography to define radiographic
215 ding edge of active states propagated in the anteroposterior/lateral direction over the cortex at app
216 re analyzed to determine trabecular meshwork anteroposterior length and 3 anterior chamber angle widt
217 tive association between trabecular meshwork anteroposterior length and all anterior chamber angle wi
218 tive association between trabecular meshwork anteroposterior length and all anterior chamber angle wi
219  the association between trabecular meshwork anteroposterior length and anterior chamber angle width
220                     Mean trabecular meshwork anteroposterior length was 824.86 +/- 181.77 mum.
221  associated with greater trabecular meshwork anteroposterior length.
222                    Thus, in the newborn rat, anteroposterior limb coordination relies on active burst
223 d the number of transition points at CT, the anteroposterior location of each transition point relati
224 ncreatic islet formation, and specifying the anteroposterior location of foregut organs.
225 ore Hox paralogous groups functioning in any anteroposterior location.
226 t significantly reduced from control at most anteroposterior locations, but this reduction was much m
227 ation by using a scale of grades 0-3, thymic anteroposterior measurement, and mean maximal thymic lob
228                                              Anteroposterior measurements of the middle facet (MF) an
229                          We also observed an anteroposterior migration of medial edge epithelial cell
230 ased significantly for each 1-cm increase in anteroposterior, minimum, and mean nodule diameter (1.78
231  patterned gene expression domains along the anteroposterior neuraxis, midline, and streak/tailbud.
232 path finding defects along the length of the anteroposterior neuraxis.
233 g cell fate specification, axon guidance and anteroposterior neuronal polarization.
234 o the anatomo-functional parcellation of the anteroposterior OFC gradient observed for secondary vers
235 n and patient orientation in the x-ray beam (anteroposterior or posteroanterior).
236 (P < 0.001) during double support and slower anteroposterior (P < 0.001) and mediolateral (P = 0.002)
237      Normal annulus displayed early-systolic anteroposterior (P<0.001) and area (P=0.04) contraction,
238 0, co-regulated by GLI3, is required for the anteroposterior pattern in which the flank ectoderm acqu
239  of neural markers in apparently appropriate anteroposterior pattern.
240 ior of the Drosophila oocyte is required for anteroposterior patterning and germ cell development dur
241 ng is not required for limb proximodistal or anteroposterior patterning but that RA inhibition of FGF
242                           Thus, the study of anteroposterior patterning in insects that lack Bicoid c
243 y which cells can integrate dorsoventral and anteroposterior patterning information.
244 ral midlines of the entire neuraxis, whereas anteroposterior patterning is controlled by several disc
245 per culture volume) deterministically alters anteroposterior patterning of primitive streak (PS)-like
246 ulating the gurken transport factor K10, and anteroposterior patterning of the blastoderm by tuning t
247  transcription factors have crucial roles in anteroposterior patterning of the nervous system and mes
248 also required for the correct integration of anteroposterior patterning signals with dorsoventral det
249  In contrast to earlier stages of Drosophila anteroposterior patterning, this transition is not well
250 sion, but was involved in the control of the anteroposterior patterning.
251 , such as the segmentation genes controlling anteroposterior patterning.
252         These measurements can be made on an anteroposterior pelvis radiograph, which is an inexpensi
253                                           On anteroposterior pelvis radiographs, we measured "pistol
254  (jbug)/filamin, we show that maintenance of anteroposterior planar polarization requires the notum e
255                                       In the anteroposterior plane, the neuropil possesses four layer
256 ntered on and tilted parallel to hippocampal anteroposterior plane.
257 developing gill arches establishes gill arch anteroposterior polarity and maintains the proliferative
258 , palatal shelves display oronasal (O-N) and anteroposterior polarity before the onset of fusion, but
259                                              Anteroposterior polarity in early C. elegans embryos is
260 utants lacking RIG-3 also had defects in the anteroposterior polarity of the ALM mechanosensory neuro
261 nt and Frizzled proteins in establishing the anteroposterior polarity of the mechanosensory neurons A
262  PLR-1 activity in the neuron AVG causes its anteroposterior polarity to be symmetric or reversed bec
263 ling has been implicated in establishing the anteroposterior polarity within maturing somites and in
264 tivation rescued membrane protrusion but not anteroposterior polarization of F-actin dynamics of PI(3
265                    Here we show that initial anteroposterior polarization of the early forelimb field
266 hedgehog (Shh), that progressively specifies anteroposterior positional identities in the posterior d
267                                          The anteroposterior positioning and the mechanism inducing S
268 tures support the distinct role of the OL in anteroposterior positioning of connective tissues propos
269 nals modulate the responses to Dpp/Tin along anteroposterior positions by cooperating with Dpp/Tin du
270                         In all subjects, the anteroposterior positions of the horizontal rectus pulle
271 and and Gli3, genes previously implicated in anteroposterior pre-patterning of the limb-forming regio
272 th regard to their origin in the three early anteroposterior progenitor domains, and their comparison
273 ), and unit recordings in rats, we show that anteroposterior propagation of neocortical slow-waves co
274  a 7% improvement in SNR at the mean maximal anteroposterior prostate dimension in this cohort and a
275                                 Standardized anteroposterior radiographs of the knee in extension wer
276 ma representative of acute inflammation, and anteroposterior radiographs of the pelvis and lateral ra
277              All patients underwent standing anteroposterior radiography of the knee prior to arthros
278 ancient bilaterian roles in dorsoventral and anteroposterior regionalisation of the ectoderm.
279 tes, and individual mutant NC from different anteroposterior regions underwent fate changes, losing n
280 ns that were well organized topographically (anteroposterior = rostrocaudal).
281  OIS response ("activation") in an extensive anteroposterior sector of SII.
282  organization in each area displays a global anteroposterior SF gradient and local patches.
283  genes we identified, rax-2 and rax-3 affect anteroposterior signaling or fate specification and rax-
284                                              Anteroposterior standing radiographs with the knee in ex
285 ed along the dorsoventral, mediolateral, and anteroposterior striatal axis.
286 this pathway is involved in both the initial anteroposterior subdivision of ventral CNS midline fates
287  Xenopus revealed three molecularly distinct anteroposterior subdivisions, identified as precommissur
288 structure primarily exposed to predominantly anteroposterior tension via anterior and posterior attac
289 ons of the disc under either mediolateral or anteroposterior tension.
290 : the proximodistal (shoulder to finger) and anteroposterior (thumb to little finger) axes.
291                             Mediolateral and anteroposterior tilt angle, degree of perforation, and d
292 e/Kupffer's vesicle, PCP signaling links the anteroposterior to left-right embryonic polarity.
293 ed at different levels in VMpo, based on the anteroposterior topographic organization of selectively
294 minations were distributed with a consistent anteroposterior topography over the posterior half of th
295 ed many STT cells in laminae I and V with an anteroposterior topography.
296 yes, 61.5%) and thick stage 3 membranes with anteroposterior traction concerning for progression to s
297                    Controls were matched for anteroposterior tumor epicenter and follow-up duration.
298                    These findings mirror the anteroposterior valence-specific gradient reported in ro
299 easible and comparable to x-ray guidance for anteroposterior vessels at 3 T in a vascular phantom.
300 ts suggested that the dorsoventral (BMP) and anteroposterior (Wnt/GSK3) patterning gradients are inte

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