ライフサイエンスコーパス: anti-

1 ers (cis/syn, cis/anti, trans/syn, and trans/anti).

2 the NHC backbone (vs the initially expected anti).

3 ucleobase into two different domains (syn or anti).

4 reactive halogenated radicals (6f,g) (>15:1 anti).

5 hoxy group is oriented toward the other (syn-anti).

6 "Pro") or away from it, toward its reverse ("Anti").

7 naute-like gene) that are antimorphic [alg-1(anti)].

8 on correlated with ribosome affinity for the anti (1,4)-regioisomers as revealed by measured Kd value

9 nocyclohexane can be differentiated using Sc[anti-(-)-1](2) in the same ligand displacement assay.

10 of compound 6 can be fixed predominantly to anti (17a and 17b) by introducing bulky alkyl groups (e.

11 acquired for 2 h after a bolus injection of anti-(18)F-FACBC (366 +/- 51 MBq).

12 Pelvic nodal status correlated with anti-(18)F-FACBC findings in 7 of 9 patients and was ind

13 s after intravenous injection of 300-410 MBq anti-(18)F-FACBC followed by static body images.

14 evaluated the whole-body radiation burden of anti-(18)F-FACBC in humans.

15 Anti-(18)F-FACBC is a promising radiotracer for imaging

16 The present study examines anti-(18)F-FACBC uptake in patients with newly diagnosed

17 e that an approximately 370-MBq injection of anti-(18)F-FACBC yields good imaging and acceptable dosi

18 3-(18)F-fluorocyclobutane-1-carboxylic acid (anti-(18)F-FACBC) is a recently developed ligand that pe

19 3-(18)F-fluorocyclobutane-1-carboxylic acid (anti-(18)F-FACBC)is a synthetic l-leucine analog that ha

20 This work demonstrates that like anti-[18F]FACBC, [18F]16 and [18F]17 are excellent candi

21 The conformation of the trans-anti-(1S,2R,3S,4R)-N(2)-[1-(1,2,3,4-tetrahydro-2,3,4-tri

22 a right-handed helix with all nucleotides in anti, 2'-deoxyribose conformations within the C2'-endo/C

23 P (4b) with epi-isozizaene synthase gave [11(anti)-(2)H]epi-isozizaene (3b), indicating that the S(N)

24 levels of spontaneously appearing monoclonal anti-(2-->8)-alpha-Neu5Ac did not cause autoimmunity.

25 The lack of pathology mediated by anti-(2-->8)-alpha-Neu5Ac may be explained by different

26 Natural, anti-(2-->8)-alpha-Neu5Ac present in most adults, vaccin

27 by the unusual physicochemical properties of anti-(2-->8)-alpha-Neu5Ac.

28 Synthesis of a variety of 8,16-disubstituted-anti-[2.2]metacyclophanedienes (CPD) with alkenyl and al

29 mbinant DH4 with chemoenzymatically prepared anti-(2R,3R)-2-methyl-3-hydroxypentanoyl-ACP (2a-ACP) ga

30 EBS [KS6][AT6], DEBS ACP6, and TYLS KR1 gave anti-(2R,3R)-6-ACP that underwent syn dehydration cataly

31 y syn-dehydration of the ACP-bound substrate anti-(2R,3R,4S,5R)-2,4-dimethyl-3,5-dihydroxyheptanoyl-A

32 e syn-(2S,3R)-2b-ACP, syn-(2R,3S)-2c-ACP, or anti-(2S,3S)-2d-ACP generated in situ by DEBS KR1, DEBS

33 4, with a 20-fold greater kcat/K(m) than the anti-(2S,3S)-diketide-SNAC 14, and a 40-fold advantage o

34 ree isomeric forms with hydrides in syn (2), anti (3), and cis (4) conformations have been characteri

35 te a curative CTL response, is necessary for anti--4-1BB mAb to induce a CTL response leading to the

36 (OHMT)Cl in solution as a mixture of syn and anti (60:40 at 0.015 M) nitrile-free isomers, but these

37 99m)TcO]depreotide (6.58% ID/g) than for the anti [(99m)TcO]depreotide (3.38% ID/g).

38 formed on Sprague-Dawley rats using syn- and anti-(99m)Tc-L- and -D-MAEC coinjected with (131)I-OIH.

39 The clearances of syn- and anti-(99m)Tc-L-MAEC in the rats were higher than the cle

40 a clearance ratio in humans ranged from 45% (anti-(99m)Tc-L-MAEC) to 74% (syn-(99m)Tc-D-MAEC) with th

41 The sheared anti-anti (A.A trans Hoogsteen/Sugar-edge) alignment provides

42 t a predominant conformation: a sheared anti-anti (A.A trans Hoogsteen/Sugar-edge) alignment similar

43 (rGGCAAGCCU)(2) duplex has sheared A(anti).A(anti) (A.A trans Hoogsteen/Sugar-edge) pairs in which th

44 The 5'(rGGCAAGCCU)(2) duplex has sheared A(anti).A(anti) (A.A trans Hoogsteen/Sugar-edge) pairs in

45 he N(CH2)3N units on each side are in doubly anti (aa) conformations that put the aryl rings as far a

46 ogen-containing coronene-type molecules like anti-(ab)2-PBI 15, syn-(ab)2-PBI 16, and syn-(ab)2-PTE 1

47 tion having one PD(+) ring syn and the other anti (abbreviated uns) was seen, and the relative amount

48 When SO2 is anti, addition is not observed.

49 odies (mAb), designed to stimulate immunity [anti-(alpha)-CD137, alpha-CD40] or relieve immunosuppres

50 could be inhibited with a function-blocking anti--alpha(4) integrin antibody.

51 This produces two FMN conformations (syn and anti) analogous to DNA.

52 sing 2-nitrobenzaldehyde (up to 93:7 dr (syn:anti) and 93% ee).

53 in various orientations [C*C, A*G, and G*G (anti) and A*G and G*G (syn)] and compare the results to

54 or the purine base, as expected for A(syn)*T(anti) and G(syn)*C(+)(anti) HG base pairing, HG type hyd

55 x predominantly adopts anticonformation ( 2A-anti) and possesses triplet ground state.

56 s performed with beta-hydroxy aldehydes 37a (anti) and the corresponding p-methoxybenzyl (PMB) ether

57 having the same G-arrangement (anti:anti:syn:anti) and the top G-tetrad having the reversed G-arrange

58 symmetric (er > 99:1) total synthesis of (+)-anti- and (-)-syn-mefloquine hydrochloride from a common

59 ymmetric (>99:1 e.r.) total synthesis of (+)-anti- and (-)-syn-mefloquine hydrochloride from a common

60 stallographic analysis of derivatives of (+)-anti- and (-)-syn-mefloquine is used to lay to rest a 40

61 The synthetic (+)-anti- and (-)-syn-mefloquine samples were derivatized wi

62 and these are subsequently converted to (+)-anti- and (-)-syn-mefloquine, respectively.

63 nd these are subsequently converted into (+)-anti- and (-)-syn-mefloquine, respectively.

64 crotyl reagents afford the corresponding 1,3-anti- and 1,3-syn-methyl-substituted "homocrotylated" al

65 Surprisingly, 2,3-anti- and 2,3-syn-alpha-methyl-beta-hydroxy aldehydes re

66 2 (X = Mg) appearing as transitional between anti- and nonhomoaromatic.

67 ngaging in protein-protein interactions with anti- and pro-apoptotic Bcl2 family members, thereby exe

68 dihydrodiol and BPDE-2 treatment, changes in anti- and pro-apoptotic events in the Bcl-2 family of pr

69 We provide evidence that B56epsilon has both anti- and pro-apoptotic functions.

70 Dimeric interactions among anti- and pro-apoptotic members of the BCL-2 protein fam

71 , thus indicating the involvement of various anti- and pro-apoptotic regulators in the signaling casc

72 Dissection of anti- and pro-apoptotic signalling events triggered by T

73 ein transduction to identify novel, opposing anti- and pro-cytokine-inducing roles for RhoA in the re

74 t directly affect the expression of Foxp3 or anti- and pro-inflammatory cytokines in T(reg) cells, su

75 or necrosis factor-alpha (TNF-alpha) are key anti- and pro-inflammatory mediators elicited during the

76 PARs exhibit both anti- and pro-inflammatory properties, although recent e

77 aging to date and the first to discriminate anti- and pro-longevity genes, revealing new insights on

78 Tiam1 and P-Rex1, two Rac GEFs, promote Rac1 anti- and pro-migratory signalling cascades, respectivel

79 l is proposed for quantifying simultaneously anti- and pro-oxidant activities as function of concentr

80 -induced dysregulations of the expression of anti- and pro-oxidant enzymes, mitochondrial biogenesis

81 ous redox agent that can function as both an anti- and pro-oxidant.

82 al conditions, polyphenols may manifest both anti- and pro-oxidative activity.

83 phages have been shown previously to be both anti- and proangiogenic, and their role in regulating an

84 At 7 weeks, a combination of nonclassic anti- and proapoptosis genes appear to be involved in ph

85 Both anti- and proapoptotic activities have been reported to

86 Anti- and proapoptotic BCL-2 family proteins not only re

87 upt the protein-protein interactions between anti- and proapoptotic Bcl-2 proteins.

88 Bcl-2 family proteins include anti- and proapoptotic factors that play important roles

89 DL(Healthy) on the activation of endothelial anti- and proapoptotic pathways and to determine which c

90 optosis through shifts in the balance of the anti- and proapoptotic proteins FLIP and FADD.

91 Here we studied interactions among anti- and proapoptotic proteins of the Bcl-2 family in l

92 the first to show that Hax-1 is a family of anti- and proapoptotic regulators that may modulate cell

93 s a pleiotropic cytokine that activates both anti- and proapoptotic signaling pathways, with cell fat

94 lead to the simultaneous activation of both anti- and proapoptotic signaling pathways; the balance u

95 CP in modulating the responses between these anti- and profibrotic cytokines in the initiation and pr

96 pe I IFNs regulate the balance between IL-10 anti- and proinflammatory activity, and provide insight

97 We hypothesized that anti- and proinflammatory dimensions of beta-arrestin2 a

98 appaB (nuclear factor kappaB), expression of anti- and proinflammatory factors and of the MAP (mitoge

99 was undertaken in order to exploit both the anti- and proinflammatory properties attributed to the v

100 ferentiation remains elusive given that both anti- and promyogenic activities have been described.

101 In this study, we have identified both anti- and proviral roles of autophagy in the compatible

102 Dechlorane Plus (anti- and syn-) and alpha- and beta-tetrabromoethylcyclo

103 determine how pol beta discriminates between anti- and syn-8-oxoG, we introduced a point mutation (R2

104 as been developed to make the optically pure anti- and syn-beta-substituted cysteine and serine deriv

105 Moreover, both the anti- and syn-BrP-LPA significantly reduced tumors at 3

106 roup increases the energy difference between anti- and syn-chairs with primary amino acid catalysts a

107 n has dual coding potential by virtue of its anti- and syn-conformations, base pairing with cytosine

108 (BTBPE), and hexabromocyclododecane (HBCDD), anti- and syn-Dechlorane plus were detected at levels co

109 ion results in stereodivergent products with anti- and syn-diastereomers both in good diastereoselect

110 bstituted cryptophanes gives rise to the two anti- and syn-diastereomers.

111 the assignment of the stereochemistry of the anti- and syn-diepoxy and -tetraepoxy derivatives as wel

112 rcinogenic metabolite, and the corresponding anti- and syn-diol epoxides of BcF (3 and 4) in which th

113 s, trans-dihydrodiols, and the corresponding anti- and syn-diol epoxides.

114 NA complex has 8-oxoG in equilibrium between anti- and syn-forms.

115 elected by Bs-FtsZ, while Mj-FtsZ binds both anti- and syn-geometries.

116 throughput, quantitative, and translational (anti-) angiogenesis and antiangiogenesis research.

117 led multiple anti-anti conformations, no syn-anti <--> anti-anti transformations were observed.

118 ow quite different relative stabilities: syn-anti > anti-anti > anti-syn > syn-syn.

119 ferent relative stabilities: syn-anti > anti-anti > anti-syn > syn-syn.

120 diastereoselective syntheses of a variety of anti, anti-stereotriads, the direct synthesis of which h

121 and to determine the lower cut-off value of anti- anti-TTG level that best predicts CD in children w

122 nges in expression of critical pro-, but not anti-, apoptotic genes.

123 n be partially attributed to alterations in (anti)-apoptotic gene expression.

124 8), microRNA guide strand selection by ALG-1(anti) appeared normal, but microRNA* strand release was

125 some microRNA* strands present in the ALG-1(anti) Argonaute far in excess of the corresponding matur

126 The retinal is 13-cis,15-anti, as known from vibrational spectroscopy.

127 ation of the absolute stereochemistry of (+)-anti- as well as (-)-syn-mefloquine.

128 when the damaged base is syn than when it is anti, at the higher temperature.

129 m the dual coding potential where 8-oxo-dGTP(anti) base pairs with cytosine and 8-oxo-dGTP(syn) uses

130 simple model accurately predicts the bonding/anti- bonding modes that are measured experimentally.

131 he two distinct CH3CHOO conformers, syn- and anti-, both of which react readily with SO2 and with NO2

132 ailable for these 10S (+)- and 10R (-)-trans-anti -[BP]-N(2)-dG adducts in double-stranded deoxyoligo

133 ene-derived N (2)-dG adduct, 10 S(+)- trans- anti-[BP]- N (2)-dG ([BP]G*), reveal that an incoming dA

134 We investigated the 10S (+)-trans-anti-[BP]-N(2)-2'-deoxyguanosine (G*) adduct in double-s

135 via trans epoxide opening to form (+)-trans-anti-[BP]-N(2)-dG ((+)-ta[BP]G) and (-)-trans-anti-[BP]-

136 nti-[BP]-N(2)-dG ((+)-ta[BP]G) and (-)-trans-anti-[BP]-N(2)-dG ((-)-ta[BP]G), respectively.

137 pyrene-derived N(2)-dG adduct, 10S-(+)-trans-anti-[BP]-N(2)-dG ([BP]G*), is processed in Dpo4, the we

138 vironmental carcinogen, is the 10S (+)-trans-anti-[BP]-N(2)-dG adduct (G*), which resides in the B-DN

139 The modeling required that the (+)-trans-anti-[BP]-N(2)-dG adduct adopt the syn conformation in e

140 leotides are inserted opposite the (+)-trans-anti-[BP]-N(2)-dG adduct by bacteriophage T7 DNA polymer

141 corporation opposite the bulky 10S (+)-trans-anti-[BP]-N(2)-dG adduct by Dpo4.

142 The 10S (+)-trans-anti-[BP]-N(2)-dG adduct can cause all three base substi

143 mental observations concerning the (+)-trans-anti-[BP]-N(2)-dG adduct in double-stranded DNA with the

144 We modeled the (+)-trans-anti-[BP]-N(2)-dG adduct opposite incoming dGTP, dTTP an

145 Dpo4 is able to bypass the 10S (+)-trans-anti-[BP]-N(2)-dG adduct, albeit to a lesser extent than

146 attacks DNA to form the major 10S (+)-trans-anti-[BP]-N(2)-dG adduct, which has been shown to be mut

147 group of guanine to form the major (+)-trans-anti-[BP]-N(2)-dG adduct.

148 The dN:(+)-trans-anti-[BP]-N(2)-dG base-pair is strained to shield the bu

149 incorporation preference opposite (+)-trans-anti-[BP]-N(2)-dG by T7 DNA polymerase contributes to pr

150 utational studies suggest that 10S (+)-trans-anti-[BP]-N(2)-dG can be accommodated in the active site

151 carcinogen-DNA adducts, including (+)-trans-anti-[BP]-N(2)-dG derived from the reaction of (+)-anti-

152 ulations of dTTP and dGTP opposite (+)-trans-anti-[BP]-N(2)-dG exhibited more instability in interact

153 zation of each nucleotide opposite (+)-trans-anti-[BP]-N(2)-dG in the +1 position (T > G > A > or = C

154 eferential insertion of A opposite (+)-trans-anti-[BP]-N(2)-dG is independent of the sequence context

155 In addition, extension past (+)-trans-anti-[BP]-N(2)-dG may pose a greater block to a high fid

156 cidated why A is inserted opposite (+)-trans-anti-[BP]-N(2)-dG most frequently, while T and G are ins

157 While the dATP: (+)-trans-anti-[BP]-N(2)-dG pair was well accommodated within the

158 Bulky adducts such as (+)-trans-anti-[BP]-N(2)-dG primarily block DNA replication, but a

159 hydrogen bond between dCTP and the (+)-trans-anti-[BP]-N(2)-dG residue evolved during the simulation,

160 The dCTP: (+)-trans-anti-[BP]-N(2)-dG system had the least number of stabili

161 udies of nucleotide incorporation, (+)-trans-anti-[BP]-N(2)-dG was modeled in the syn conformation in

162 ss of the base positioned opposite (+)-trans-anti-[BP]-N(2)-dG, extension of the primer past the lesi

163 exocyclic amino group of guanine ((+)-trans-anti-[BP]-N(2)-dG, or G*).

164 er-extension of each base opposite (+)-trans-anti-[BP]-N(2)-dG, we carried out molecular modeling and

165 n intermediate preference opposite (+)-trans-anti-[BP]-N(2)-dG, were accommodated reasonably well, bu

166 ernary complex containing this 10S (+)-trans-anti-[BP]-N(6)-dA adduct in the templating position with

167 formations of the 10S (+)- and 10R (-)-trans-anti-[BP]-N(6)-dA adducts through molecular dynamics (MD

168 dies have been carried out for 10S-(+)-trans-anti-[BP]-N2-dG ((+)-ta-[BP]G), a lesion derived from th

169 [a]pyrene-derived N2-dG adduct, 10S(+)-trans-anti-[BP]-N2-dG ([BP]G*), is processed in a well-charact

170 bserved for the stereoisomeric 10S (+)-trans-anti-[BP]G adduct in both the C-[BP]G and meC-[BP]G sequ

171 d NMR study indicates that the 10R (-)-trans-anti-[BP]G adduct undergoes a transition from a minor gr

172 enine, forming bulky (+)-1R- or (-)-1S-trans-anti-[BPh]-N6-dA adducts.

173 lammatory response syndrome (CARS; excessive anti-, but no/low proinflammatory mediators).

174 These observations have demonstrated that an anti- but not proapoptotic activity is the prevailing ev

175 dry mouth but F = 0, increased expression of anti- CA6 was noted compared to the F <1 group (p = .032

176 shed a role of vascular-disrupting agents as anti- cancer agents.

177 An anti--carcinoembryonic antigen IgG antibody (MN14) was c

178 he total (CD68(+)), pro- (CD14(+) = M1), and anti- (CD206(+) = M2) inflammatory macrophages, crown-li

179 ) binds only to chains rotated 19.5 degrees (anti-) clockwise from the [001] direction.

180 enger) strands, and immunoprecipitated ALG-1(anti) complexes contained nonstoichiometric yields of ma

181 nd protein populations associated with ALG-1(anti) complexes in vivo.

182 uorophenyl) TEFDDOL, a quite unusual "pseudo-anti" conformation of the diol, with no intramolecular (

183 i conformations in RNA and (high-anti)-(high-anti) conformations in DNA.

184 ted) conformer of both molecules to the syn (anti) conformer.

185 ar-reaching analogies are established among (anti-) cooperative collective behaviors in chemical kine

186 ly associated with RA (P<10(-4)): *0301 with anti- cyclic citrullinated peptide-negative RA and *0701

187 this slow motion, in contrast to the 8-oxoG (anti):dCTP system.

188 rough a S(N)1 mechanism with very high (>95% anti) diastereocontrol.

189 n) and benzo[c]phenanthrene (BcPh) series 2 (anti) diol epoxides.

190 IgA anti-tissue transglutaminase and/or IgA anti- endomysium permitted diagnosis or exclusion of CD

191 collective behaviors in chemical kinetics, (anti-)ferromagnetic spin models in statistical mechanics

192 Phase boundaries in multiferroics, in which (anti-)ferromagnetic, ferroelectric and ferroelastic orde

193 one- and two-dimensional spin systems with (anti)-ferromagnetic interactions controlled by their sym

194 uctural studies demonstrate that 8-OG(syn):G(anti) forms a stable pair in the interior of the duplex,

195 s the cap in multiple conformations (syn and anti) giving rise to a relatively plastic and nonspecifi

196 modulation was done by treatments with DTA-1 anti- glucocorticoid-induced tumor necrosis factor recep

197 he (NIASF), no increase in the prevalence of anti- gp130-RAPS antibodies was observed in serum or syn

198 The overall anti-->syn transition rate and relative probability of t

199 oside underwent spontaneous and reproducible anti-->syn transitions.

200 expected for A(syn)*T(anti) and G(syn)*C(+)(anti) HG base pairing, HG type hydrogen bonding could on

201 ith anti-anti conformations in RNA and (high-anti)-(high-anti) conformations in DNA.

202 Anti- HNA-3a is one of the product-derived factors and a

203 ATS is similar in action to anti-(human)thymocyte globulin (ATG), which is used clin

204 The 7-phosphanorbornene anti-(i)Pr(2)NP(C(6)H(8)) could be synthesized (70% isol

205 Maternal serum concentrations of IgG anti- Ia, -Ib, -III and -V polysaccharides and anti-BP-1

206 Anti- IgG seroconversion occurred in eight -seronegative

207 in survival was found between the different anti- IgG serogroups (D-R-, D-R+, D+R-, or D+R+).

208 evels for pro (IFN-gamma and TNF-alpha)- and anti (IL-4 and IL-10)-inflammatory cytokines also were d

209 allergen inhalation and treatment trials the anti-(IL-5) therapeutic Mepolizumab).

210 Coculture with anti--IL-10 antibody increased p70 production.

211 Combined Flt3L and single-dose anti--IL-10 antibody pretreatment improved lesion cure r

212 A single dose of anti--IL-10 antibody significantly improves Flt3L immuno

213 a postinsertional complex shows 8oG(syn).dA (anti) in a Hoogsteen-like base pair at the 3' terminus,

214 atio of the two limiting conformers (syn and anti) in solution and the extent of conjugation between

215 s exist as a mixture of E(syn)-(alpha) and Z(anti) in solution.

216 nsition states, endo-prox-anti and endo-dist-anti, in the pentadiene/PyrNO reaction, leading to nearl

217 RNA* strands were selected as guide by ALG-1(anti), indicating a defect in normal specificity of the

218 ponses by differentially regulating pro- and anti- inflammatory cytokine production in innate immune

219 modulate the expression of selected pro- and anti- inflammatory mediators such as IL-6 and IL-33.

220 ave been reported to modulate either pro- or anti- inflammatory programs, which may be specific to th

221 stances is linked mainly to the antioxidant, anti- inflammatory, anti-proliferative and cardioprotect

222 For 8-oxo-dGTP(anti) insertion, a novel divalent metal relieves repulsi

223 Its reversible conformational (syn and anti) interconversion and photodecomposition were observ

224 ith or without the addition of 250 microg of anti--interleukin (IL)-10 antibody on day 9.

225 the conversion of the anti (syn) to the syn (anti) isomer at 66.2 degrees C.

226 the conversion of the anti (syn) to the syn (anti) isomer at 71.0 degrees C.

227 115.2 (109.0) kJ/mol for the anti/syn- (syn/anti)-isomerization of 8 and 9, respectively.

228 ALG-1(anti) miRISC (microRNA induced silencing complex) fails

229 to three contiguous stereocentres in a (syn, anti)-mode with excellent regio and diastereoselectiviti

230 osuppressive agents CTLA4-Ig + anti-CD40L or anti-(murine)thymocyte serum (ATS).

231 Sjorgen's Syndrome (SS) and HCV, presence of anti- muscarinic receptor type 3 (M3R) antibodies in SS,

232 In addition, alg-1(anti) mutants dramatically overaccumulated microRNA* (pa

233 alg-1(anti) mutants have dramatically stronger microRNA-relate

234 (syn, Pseudomonas fluorescens, gi 70731221 ; anti, Mycobacterium smegmatis, gi 118470554 ) document t

235 Anti- N-methyl-D-aspartate receptor (NMDAR) encephalitis

236 )+(R)] and the elimination mechanism (syn or anti), not substituent effects, determined the configura

237 he stereochemical configurations (syn versus anti) of the THF groups near the termini.

238 he N-heterocyclic carbene ligand IMes to fac,anti-(ONO(Cat))Re(O)(mu-O)2Re(O)(ONO(Cat)) cleaves the d

239 ide and the dimeric rhenium(VII) complex fac,anti-(ONO(Cat))Re(O)(mu-O)2Re(O)(ONO(Cat)).

240 ular flux analysis of cells transfected with anti- or pre- miR-29a confirmed that miR-29a inhibits mi

241 ve been discovered as therapeutic targets in anti- or pro-angiogenic drug development.

242 It may exhibit anti- or pro-apoptotic activity depending on the nature

243 at this pathway may be a suitable target for anti- or proangiogenesis strategies.

244 ssenger RNA (pre-mRNA) splicing to induce an anti- or proapoptotic response.

245 as a bifunctional regulator promoting either anti- or profibrogenic response, depending on milieu.

246 MSCs can respond to tissue injury by anti- or proinflammatory activation.

247 ies in both mice and humans suggest that the anti- or proinflammatory nature of high density lipoprot

248 The anti- or prooxidant effects of green tea catechins have

249 nin is a convergent site for the activity of anti- or propsychotic drugs, opening a possibility for n

250 possessing di- or trisubstituted alkenes and anti- or syn- relative stereochemistry at the allylic an

251 ounds, Pd(II) is capable of promoting either anti- or syn-addition.

252 with aromatic aldehydes and preparing either anti- or syn-aldol adducts with very high enantioselecti

253 ite that can tolerate 8-oxo-dG in either the anti- or syn-conformation.

254 n them, hydrogen bonds relating parallel and anti- parallel beta strands, spatial adjacencies relatin

255 Anti- PECAM/SOD, but not nontargeted counterparts, accum

256 Therefore the anti- Ph(1)-leukemia effect of the combination of BCR/AB

257 t mammary gland and the pro-(BAX:Bcl(2)) and anti-[PKC alpha*(Bcl(2)/BAX)] apoptotic ratios were eval

258 '-epi-46, and 61) and several low-micromolar anti- Plasmodium falciparum lead compounds (i.e., 46, 2,

259 Neither in vivo anti- Pp IgG antibody nor in vitro anti- Pp T-cell respo

260 r in vivo anti- Pp IgG antibody nor in vitro anti- Pp T-cell response and resultant production of RAN

261 llate (EGCG), and matrix pH (2-7) on the net anti-/pro-oxidant activity of EGCG in flaxseed oil-in-wa

262 ing that quinoxaline antibiotics could exert anti- proliferative effects by inhibition of chromosomal

263 mutant ALG-1 and found that the mutant ALG-1(anti) protein fails to interact with numerous miRISC cof

264 viously shown to exhibit "pro-[PSI(+)]" and "anti-[PSI(+)]" effects, respectively.

265 he different stereochemical courses (syn and anti) result from different structural strategies for de

266 ) are compared with a commercially available anti- Salmonella antibody and the antimicrobial peptide

267 t)/anti-OH, SERO(B) at 32548 cm-1 to Gpy(up)/anti, SERO(C) at 32545 cm-1 to Gph(out)/anti, SERO(D) at

268 (up)/anti, SERO(C) at 32545 cm-1 to Gph(out)/anti, SERO(D) at 32560 cm-1 to Anti(py)/anti, SERO(E) at

269 out)/anti, SERO(D) at 32560 cm-1 to Anti(py)/anti, SERO(E) at 32537 cm-1 to Anti(up)/anti, SERO(F) at

270 (py)/anti, SERO(E) at 32537 cm-1 to Anti(up)/anti, SERO(F) at 32353 cm-1 to Gpy(out)/syn, SERO(G) at

271 ection, survival, yearly posttransplantation anti- serology, development of acute toxoplasmosis, and

272 ed on pretransplantation donor and recipient anti- serology, immunosuppression, allograft rejection,

273 clobutane species not being able to have an (anti) substituent pointing toward the HIPTO group.

274 5.2 (111.1) kJ/mol for the conversion of the anti (syn) to the syn (anti) isomer at 66.2 degrees C.

275 6.0 (112.1) kJ/mol for the conversion of the anti (syn) to the syn (anti) isomer at 71.0 degrees C.

276 rase interactions that influence templating (anti-/syn-equilibrium) of 8-oxoG while modulating fideli

277 re the thiophene rings have the sulfur atoms anti, the sulfur atoms in 5 are completely syn.

278 , were asymptomatic and required no specific anti- therapy.

279 n mast cells was suppressed by anti-IL-1 and anti- thymic stromal lymphopoietin (TSLP) and was enhanc

280 tive and specific screening serologic tests (anti- tissue transglutaminase antibodies IgA [anti-TTG]

281 r tests (IgA anti-dpgli, IgG anti-dpgli, IgA anti- tissue transglutaminase, and IgA anti-endomysium)

282 nverted these benign effects of RSFC from an anti- to a proinflammatory status.

283 ert the consequence of Ang2 stimulation from anti- to pro-angiogenic.

284 Importantly, the promotion of a high anti- to pro-apoptotic Bcl-2 family member ratio by acid

285 As mice mature, BAK is converted from anti- to pro-death function in virus-infected spinal cor

286 " cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner.

287 ansannulation reactions producing the trans, anti, trans estrane 56 in 12% overall yield.

288 xides exist as four conformers (cis/syn, cis/anti, trans/syn, and trans/anti).

289 The in vitro and in vivo anti- Trypanosoma cruzi activity of the pyrazole-contain

290 gues with selective and significant in vitro anti- Trypanosoma cruzi activity.

291 or psoriasis, but pDCs are also involved in (anti-)tumor immunity.

292 In contrast, Ssa1 was shown to have anti-[URE3] effects, since overexpression of Ssa1 cures

293 Aflibercept has emerged as a new anti- vascular endothelial growth factor (VEGF) therapy

294 ecrosis and the mechanisms that regulate its anti- vs proapoptotic activities.

295 The stereochemical preference (syn or anti) when prochiral radicals add to prochiral acceptors

296 ncreases 15-syn-retinal at the expense of 15-anti, which is the predominant isomer in the wild type,

297 in polymorph A away from each other (termed anti), while in polymorph B one methoxy group is oriente

298 he dimeric quadruplex contains two stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads, one of which

299 quadruplex contains two stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads, one of which forms a n

300 x contains two stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads, one of which forms a newly ident