ライフサイエンスコーパス: anti-idiotypic

1 The possibility that the anti-idiotypic 6A6 might carry an "internal image" of th

2 The findings suggest that anti-idiotypic Ab responses can be induced by T cell vac

3 nd because all of the variants that arise in anti-idiotypic Ab-treated lymphoma patients remain BCR p

4 ic efficacy, and abolished recognition by an anti-idiotypic Ab.

5 In the present study, we observed that some anti-idiotypic Ab2beta antibodies inhibited dopamine upt

6 dies in our laboratory have produced several anti-idiotypic Ab2beta antibodies that mimic the configu

7 ed for the first time that B cells producing anti-idiotypic Abs could be isolated from vaccinated pat

8 activity pattern, and the regulatory role of anti-idiotypic Abs elicited by T cell vaccination in pat

9 We hypothesized that some anti-idiotypic Abs function as divalent molecular mimics

10 ts with mAb and in active immunotherapy with anti-idiotypic Abs mimicking the CO17-1A or GA733 epitop

11 -idiotypic humoral responses and whether the anti-idiotypic Abs play a similar role in the regulatory

12 The resulting anti-idiotypic Abs were found to react with the original

13 Anti-idiotypic Abs were undetectable in animals vaccinat

14 not by immunization with the protein alone, anti-idiotypic Abs, or irradiated tumor cells.

15 e functionality of ITIM+ FcgammaR, effective anti-idiotypic and antitumoral immunity can be achieved

16 mice upon repeated i.p. dosing because of an anti-idiotypic anti-drug Ab immune response.

17 with MELIMMUNE, a combination of the murine anti-idiotypic (anti-id) monoclonal antibodies (mAb) MEL

18 iated antigen (HMW-MAA) mimicry by the mouse anti-idiotypic (anti-id) monoclonal antibody (mAb) MK2-2

19 rmine if these IgG-inhibitory antibodies are anti-idiotypic antibodies (anti-Ids).

20 ns coated with GAD65-specific mAbs to absorb anti-idiotypic antibodies (anti-Ids).

21 ntary to the autoantigen, which then induces anti-idiotypic antibodies (autoantibodies) that cross-re

22 We produced rabbit anti-idiotypic antibodies against two pathogenic and two

23 Ig-mediated protection in this assay include anti-idiotypic antibodies and downregulation of compleme

24 rheumatoid factors, in which they represent anti-idiotypic antibodies directed against antibodies to

25 Antigen mimicry of using anti-idiotypic antibodies for use as cancer vaccines has

26 he peripheral anionic site, since polyclonal anti-idiotypic antibodies generated against two monoclon

27 Anti-idiotypic antibodies provide precision tools for an

28 The anti-idiotypic antibodies recognized both the erythrocyt

29 Intravenous gammaglobulin (i.v.IG) contains anti-idiotypic antibodies that are potent inhibitors of

30 This antibody response elicits anti-idiotypic antibodies that cross-react with ANCA ant

31 Anti-idiotypic antibodies were detected in only 6 of 24

32 nt region-specific antibodies and select for anti-idiotypic antibodies with specificity for the uniqu

33 ase process manifested through production of anti-idiotypic antibodies with tobacco-like activity.

34 ement and production of cytokines, providing anti-idiotypic antibodies, and affecting the activation

35 cation of a putative auxin receptor by using anti-idiotypic antibodies.

36 x-smokers may be driven, in part, by tobacco anti-idiotypic antibodies.

37 A monoclonal anti-idiotypic antibody (anti-Id) to the chlamydial exog

38 Here, we characterize how an anti-idiotypic antibody (E1) binds antibody HM14c10, whi

39 9 used immuno-enrichment with a biotinylated anti-idiotypic antibody and streptavidin magnetic beads.

40 staining and flow cytometry using a specific anti-idiotypic antibody called E4, which recognizes this

41 A mouse monoclonal anti-idiotypic antibody directed against the polyphenol-

42 By the final visit, median anti-anti-idiotypic antibody level was 493,000.0 ng/mL, indic

43 ls and was not associated with any increased anti-idiotypic antibody production.

44 Low levels of serum anti-idiotypic antibody remained unaltered in recipients

45 ith carrier proteins or adjuvants induces an anti-idiotypic antibody response.

46 sential factor for PRRSV infection using the anti-idiotypic antibody specific to the PRRSV glycoprote

47 the use of purified viral gB protein and an anti-idiotypic antibody that mimics the image of the vir

48 double-labeled immunohistochemically with an anti-idiotypic antibody that recognizes 5-HT1B, 5-HT2A,

49 After priming by CSC or tobacco anti-idiotypic antibody, there was a 2.5-fold to threefo

50 sing purified neutrophils and CSC or tobacco anti-idiotypic antibody.

51 s unknown whether T cell vaccination elicits anti-idiotypic humoral responses and whether the anti-id

52 understanding of the regulatory role of the anti-idiotypic humoral responses induced by T cell vacci

53 ects on platelet count are not likely due to anti-idiotypic inhibition of 7E3-platelet binding and th

54 eport here peptide mimics of PC based on the anti-idiotypic interaction of T15 anti-PC antibodies.

55 he self-interaction of Fab fragments of anti-anti-idiotypic mAb GH1002 through their combining sites

56 nt active specific immunization regimens (an anti-idiotypic mAb immunization protocol (mAb-keyhole li

57 In a phase I/II clinical trial, anti-idiotypic mAb MK2-23, conjugated to keyhole limpet

58 test this idea, we studied two well-defined anti-idiotypic mAbs, T10-505 and T10-938, elicited in sy

59 Using gene-targeted mice, we show that anti-idiotypic MHC class I-restricted immunity is promot

60 ucture of the Fab fragment of the mouse anti-anti-idiotypic monoclonal antibody (mAb) GH1002 was solv

61 AA expression, we have used as immunogen the anti-idiotypic monoclonal antibody (mAb) MK2-23, which m

62 Anti-idiotypic reagents were used to detect V(H)1, V(H)3

63 blockade strategy obviates possibilities of anti-idiotypic responses that could potentially limit th

64 -reactive T cell clones were used to isolate anti-idiotypic T cell lines from immunized MS patients.

65 ggest that CDR3-specific T cells represented anti-idiotypic T cell population induced by T cell vacci

66 ts responsible for triggering CD8+ cytotoxic anti-idiotypic T cell responses by T cell vaccination in

67 eactive T cells (T cell vaccination) induces anti-idiotypic T cell responses that preferentially reco

68 eactive T cells (T cell vaccination) induces anti-idiotypic T cell responses that suppress circulatin