ライフサイエンスコーパス: antiandrogenic

1 If DDE has important antiandrogenic action in humans, it may be manifest only

2 thoxyphenyl)-1,3-propanedione] showed potent antiandrogenic activities and were superior to hydroxyfl

3 These unique antiandrogenic activities make ADEK a potential therapeu

4 dicated that the two oils had estrogenic and antiandrogenic activities.

5 ha and ERbeta agonist activity that retained antiandrogenic activities.

6 hemicals is challenging and a great share of antiandrogenic activity detected in the environment has

7 oncentrated water extract that was posing an antiandrogenic activity equal to 45.5 (+/-13.7 SD) FEq/L

8 others (17 and 19) appear to exhibit strong antiandrogenic activity in cultures of the LNCaP human p

9 Finally, the antiandrogenic activity of C47 and one derivate was conf

10 We speculate that the antiandrogenic activity of p,p'-DDE may mitigate harmful

11 (trifluoromethyl)benzonitrile (6a), exhibits antiandrogenic activity significantly greater than that

12 Antiandrogenic activity was also evaluated in LNCaP cell

13 Notably, 6a maintains its antiandrogenic activity with AR mutants W741L and T877A

14 ropanol-based ligands possessing significant antiandrogenic activity with both wild-type AR and the t

15 n bond donor group were also crucial for the antiandrogenic activity, which is consistent with previo

16 e products and their reported estrogenic and antiandrogenic activity.

17 ules seem to be important factors related to antiandrogenic activity.

18 enic activity appears to be unrelated to the antiandrogenic and antimineralocorticoid effects of spir

19 anomalies and environmental factors, such as antiandrogenic and estrogenic endocrine disrupting chemi

20 d cellular and molecular mechanisms by which antiandrogenic and estrogenic signals induce penile malf

21 yl group at ring A is important for TS-IIA's antiandrogenic and maspin induction activities.

22 Nevertheless, high antiandrogenic and minor dioxin-like and estrogenic effe

23 to the endocrine disruptors vinclozolin (an antiandrogenic compound) or methoxychlor (an estrogenic

24 In particular, many pesticides are antiandrogenic, creating a need for robust and sensitive

25 ven their close structural similarity to the antiandrogenic drug nilutamide.

26 It demonstrated a noticeable antiandrogenic effect on prostate in intact rats with en

27 TDI) values (considered as potential adverse antiandrogenic effect).

28 Phthalates have antiandrogenic effects and may disrupt lipid and carbohy

29 agents, many of which are antioxidants with antiandrogenic effects, are being tested (or soon will b

30 ates reached levels that might cause adverse antiandrogenic effects.

31 ed germ cells (MNGs) in fetal testes without antiandrogenic effects.

32 In the present study, we assessed the antiandrogenic efficacy of isosilybin B employing human

33 Untreated wastewater induced antiandrogenic, estrogenic, antiestrogenic, and retinoid

34 We propose that the antiandrogenic exposure during early development may sim

35 als that also may contribute to a cumulative antiandrogenic exposure.

36 whose progenitors had been treated with the antiandrogenic fungicide vinclozolin.

37 (estrogenic, antiestrogenic, androgenic, and antiandrogenic) in vitro and in vivo.

38 strong and direct evidence for ascribing an antiandrogenic MOA to BPA in vertebrates.

39 itigate the impact of TB, consistent with an antiandrogenic MOA.

40 lations are regularly exposed to mixtures of antiandrogenic pesticides, our results underline the nee

41 A new nonsteroidal antiandrogenic pharmacophore has been discovered using c

42 Multiple antiandrogenic phthalates exposure during fetal developm

43 at DIM exhibits potent antiproliferative and antiandrogenic properties in androgen-dependent human pr

44 shown to have estrogenic, antiestrogenic, or antiandrogenic properties; as a result, the impact of ex

45 ly greater than that of the most widely used antiandrogenic prostate cancer drugs bicalutamide (1) an

46 ver, this series of aryl hydantoins produced antiandrogenic side effects in the host, a not unexpecte

47 estive heart failure, the progestational and antiandrogenic side effects of the nonspecific aldostero

48 igh antischistosomal efficacy that were less antiandrogenic than 1.

49 Therefore, we analyzed whether antiandrogenic therapy with finasteride, which inhibits