ライフサイエンスコーパス: antibody complex

1 iew of antigen flexibility within an antigen:antibody complex.

2 ed the molecular heterogeneity of the hapten-antibody complex.

3 rease in the dissociation rate of the hapten-antibody complex.

4 the interaction and stability of the antigen-antibody complex.

5 the crystal structure of the alpha-hemolysin:antibody complex.

6 y the formation of a surface aptamer-protein-antibody complex.

7 the three-dimensional structure of the virus-antibody complex.

8 otected from inflammation induced by antigen-antibody complexes.

9 odies via differential catabolism of antigen-antibody complexes.

10 g produced the increased affinity of antigen-antibody complexes.

11 from the deformed states of gp120 in certain antibody complexes.

12 t GVHD by coadministering rapamycin and IL-2 antibody complexes.

13 re capable of using metals to bridge antigen:antibody complexes.

14 eneic donor by treatment with IL-2/anti-IL-2 antibody complexes.

15 namically characterize high-affinity antigen/antibody complexes.

16 ough activation of effector cells by antigen-antibody complexes.

17 individual antigens, antibodies, and antigen/antibody complexes.

18 d, to define the k(d) of this stable antigen/antibody complex accurately, the highest PSA concentrati

19 otting factor in such a way that the protein-antibody complex acquires a unique function.

20 alyzed an internalization process of antigen-antibody complexes after binding of RSV-specific antibod

21 humans, the resulting formation of IL-1beta-antibody complexes allowed the detection of in vivo-prod

22 ay of complement activated by, e.g., antigen-antibody complexes, also recognizes the C4 C345C domain

23 0 min of room temperature incubation for the antibody complex and after 18 min for the protein comple

24 Use of bispecific antibody complexes and (99m)Tc-DTPA-succinyl-polylysine

25 Bispecific antibody complexes and (99m)Tc-labeled negatively charge

26 feres with thrombotic properties of beta2GPI/antibody complexes and does not affect normal thrombus f

27 These defects were due to viral antigen-antibody complexes and not the chronic infection per se,

28 Precipitation of the radiolabeled receptor-antibody complexes and scintillation counting enabled qu

29 L-63 in the crystal structure of the antigen-antibody complex, and 10 HyHEL-63 residues in contact wi

30 HSP70 protein, antigen-antibody complexes, and complement were prevalent in IPF

31 cytokines bound to their receptors, allergen-antibody complexes, and innate immune receptors with the

32 The toxin-antibody complex anti-d(beta)h-saporin (DSAP) selectivel

33 esults show that neither B cells nor antigen-antibody complexes are essential for the maintenance of

34 ariety of situations in which stable antigen-antibody complexes are formed in the presence of nonreac

35 Because internalized PAM/PAM-antibody complexes are returned to secretory granules, t

36 re of the Gla domain in the Factor IX-(1-47)-antibody complex at 2.2 A is similar to the structure of

37 determined the crystal structure of the RBD-antibody complex at 2.3-A resolution.

38 ay blockade, the organization of the antigen-antibody complexes at the cell surface, and opportunitie

39 s the first to provide evidence that antigen-antibody complexes bind specifically to apoptotic neutro

40 inity, allowing simple separation of antigen-antibody complex by thermal precipitation.

41 Thus, different cytokine-antibody complexes can be used to selectively boost or i

42 cells as soluble shed antigen or as antigen-antibody complexes, causing impairment in the activation

43 utic induction of basophilia by IL3/anti-IL3 antibody complexes, combined with transfer of CD8(+) T c

44 dies, deposition of anti-double-stranded DNA antibody complexes, complement activation, and immune co

45 one in this issue, demonstrate that antigen-antibody complexes containing RNAs activate B lymphocyte

46 mation and selective precipitation of cyclic antibody complexes created by binding to trivalent hapte

47 For antigen-antibody complexes, DARS is slightly better than a numbe

48 ion of the kinetics and stoichiometry of Env-antibody complexes demonstrated the applicability of our

49 The antigen-antibody complex demonstrates a high association constan

50 It describes the structures of four AAV-antibody complexes determined by cryo-electron microscop

51 and HBoV4 capsids using structures of capsid-antibody complexes determined using cryo-electron micros

52 In mice, low-dose IL-2-anti-IL-2 antibody complexes drove group 2 innate lymphoid cells (

53 y translate to a lack of toxicity of antigen-antibody complexes during the course of infections with

54 -stain EM to model the PCSK9 antigen-J16 Fab antibody complex, followed by validation of the model by

55 influence on the affinity of the beta(2)-GPI antibody complex for the membrane vesicles.

56 formed a comparative analysis of all protein-antibody complexes for which structures have been experi

57 The antibody complexed form of sHLA was ineffective in the i

58 tion of a functional, full-length monoclonal antibody complex from transgenic Nicotiana tabacum roots

59 tation), associated with shedding of antigen-antibody complexes from endothelial cells.

60 dic cluster affects exit of internalized PAM-antibody complexes from late endosomes; internalized PAM

61 antibodies led to the release of the capsid/antibody complexes from the cell surface and their accum

62 Uptake of antibody-complexed GAD65 was Fc receptor (FcR)-mediated

63 ore this measurement can be made, the ligand-antibody complex generally has to be separated from bulk

64 Monoclonal antibody complexes have proven very useful in the study

65 Two of these were virus-antibody complexes having contrasting transcriptional ca

66 e Ig crystallizable fragment (Fc) in antigen-antibody complexes held on FDCs decreases the activation

67 ed antigens as periodically arranged antigen-antibody complexes (ICs).

68 ng of the antibody structure into the virion/antibody complex identifies two conformations of the ant

69 sh fluorescence detection of the GFP antigen-antibody complex in a similar manner.

70 acer enzyme and used to detect the herbicide-antibody complex in an ELISA format.

71 orescence analyses revealed granular antigen-antibody complexes in a subepithelial location along the

72 EMS-based mass spectrometry by analysing IgM antibody complexes in real time.

73 ight into this process, we characterized PrP-antibody complexes in solution using a fast protein liqu

74 s studies demonstrated that specific antigen-antibody complexes in the sera of patients with LD could

75 nhibits prothrombotic properties of beta2GPI/antibody complexes in wild-type mice after acute infusio

76 binding (hormone-receptor and neuraminidase-antibody complexes), in one case the net effect is close

77 Immunization with chlamydia-antibody complexes induced elevated and protective Th1 r

78 n of Fc-receptor-bearing effector cells with antibody-complexed infected cells is important in reduci

79 ncer cells followed by tracking the receptor-antibody complex internalization by confocal microscopy.

80 One the one hand, this antigen-antibody complex internalization could result in an anti

81 cination with PD1 blockade or IL-2/anti-IL-2 antibody complexes led to complete disease eradication a

82 roscopy reveals that endocytosis of the PSMA-antibody complex occurs via clathrin-coated pits.

83 e current study we demonstrate that cytokine:antibody complexes of IL-2 and anti-IL-2 mAb reduce the

84 tection to directly count individual protein-antibody complexes of protein G or herpes simplex virus

85 tation by B cells and persistence of antigen-antibody complexes on follicular dendritic cells (FDC) h

86 and the capacity to form multivalent antigen-antibody complexes on target cells were key determinants

87 CL) with exposure to X-ray film, the antigen-antibody complexes on the blot are reacted with a chromo

88 a detects the pattern of fluorescent antigen:antibody complexes on the sensor surface.

89 n the mobile phase eluted the benzodiazepine-antibody complexes onto a C-18 restricted access media (

90 e formation of citrullinated protein antigen-antibody complexes or other forms of ICs.

91 surement of the concentration of the protein-antibody complexes over 3 orders of magnitude down to th

92 iated with limited proteolysis of an antigen-antibody complex particularly in the vicinity of the bin

93 n each platform with three different antigen/antibody complexes possessing nanomolar to picomolar equ

94 Antigen-antibody complexes provide useful models for analyzing t

95 Antigen-antibody complexes provide useful models for studying th

96 three-dimensional reconstruction of the RecA-antibody complex reveal that the lobe containing the epi

97 Finally, electron microscopy of TRPM1-antibody complexes revealed a large particle that can ac

98 Structural studies on the hapten-antibody complex show that the active site contains two

99 ope chemistries differed, all 16 gp120-CD4bs antibody complexes showed geometric similarity, with ant

100 on microscopic analysis of two neuraminidase-antibody complexes shows that the conserved neuraminidas

101 on extensive structural analyses of antigen-antibody complexes.Single-particle electron cryomicrosco

102 In contrast to the case of IAV-antibody complexes, SP-D-IAV complexes attached to and a

103 Bacteria samples, treated with a fluorescent antibody complex specific to Streptococcus pyogenes, wer

104 Epitome consists of all known antigen/antibody complex structures, a detailed description of t

105 igenic interactions within the known antigen-antibody complex structures.

106 lead to the production of auto-antigen: auto-antibody complexes that are the hallmark of systemic lup

107 Unlike antibody complexes that are usually rapidly cleared, the

108 ed to Sepharose were used to isolate antigen-antibody complexes that contained few contaminating host

109 l structures of wild-type and cross-reactive antibodies complexed to BoNT/A1 at resolutions up to 2.6

110 e antigens that enhance access of the virion-antibody complex to FcgammaR-bearing cells.

111 submicrogram quantities of goat anti-hamster antibody complexed to mAb N418 elicited goat antibody-sp

112 to couple receptors for antigens and antigen-antibody complexes to adaptive and innate immune respons

113 atomic force microscopy imaging of receptor-antibody complexes to show that whereas the GluA1/GluA2

114 We show here that binding of 135S-antibody complexes to the Fc receptor (CDw32) increases

115 mpartment with fluorescent primary-secondary antibody complexes, total internal reflection fluorescen

116 ylococcal protein A-Sepharose indicated that antibody-complexed tracer was released from the liver 20

117 of these depend on the detection of a ligand-antibody complex using some kind of optical technique, e

118 ian, 558 IU/ml; range, 42 to 135,000 IU/ml), antibody-complexed virus, free specific IgG, and potenti

119 ype GFP and the formation of the GFP antigen-antibody complex was monitored.

120 We also found that an Abeta/antibody complex was present in both the plasma and the

121 y (EIS) in which the formation of an antigen-antibody complex was quantified as a function of charge

122 X-ray crystal structure of a gp120-CD4-CD4i antibody complex, we introduced changes into gp120 that

123 iakinumab and by leveraging additional IL-23:antibody complexes, we propose a mechanistic paradigm fo

124 cally with the capture arm of the bispecific antibody complex were used to demonstrate the feasibilit

125 tion of IgG sufficient to inhibit HA, virion-antibody complexes were monodispersed and not aggregated

126 Similarly, cells treated with Nef/anti-Nef antibody complexes were protected from Nef-induced apopt

127 d antibodies were capable of forming antigen-antibody complexes which could be isolated by gel filtra

128 these subpopulations of pAbs formed antigen-antibody complexes which could be isolated by gel-filtra

129 Further, incubation of the antigen-antibody complex with 11-cis-retinal failed to regenerat

130 es: crystalline GB1 and the precipitated GB1-antibody complex with a molecular weight of more than 30

131 e enhancement of 3.5 x 10(4) in favor of the antibody complex with an effective molarity of 76.7 M, r

132 are imported into the nucleus as an antigen-antibody complex with coilin.

133 his study, the effect of anti-E. chaffeensis antibody complexed with E. chaffeensis on the expression

134 Anti-E. chaffeensis antibody complexed with E. chaffeensis significantly enh

135 line heavy-chain/mature light-chain chimeric antibody complexed with HIV-1 gp120.

136 The C-pro alpha 2(I) antibody complexed with more cell proteins.

137 with hen egg white lysozyme (HEL), the D1.3 antibody complexed with the anti-lysozyme antibody E5.2,

138 tructure of a Fab fragment derived from this antibody complexed with the factor VIII C2 domain was de

139 he size distribution and affinity of protein-antibody complexes with picomolar KD values.

140 ic studies coupling the structure of antigen-antibody complexes with their antiviral function has beg