ライフサイエンスコーパス: antibody diversity

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1 ing RNA surveillance machinery in generating antibody diversity.

2 n addition to its integral roles in creating antibody diversity.

3 of the vertebrate immune system to generate antibody diversity.

4 two types of genomic alterations to increase antibody diversity.

5 matic hypermutation mechanism that increases antibody diversity.

6 n many vertebrates, and is a major source of antibody diversity.

7 nherent mutator activity that helps generate antibody diversity.

8 As a model for studying the generation of antibody diversity, a gene-targeted mouse was produced t

9 We hypothesized that higher antibody diversity across recent H1 and H3 influenza vir

10 Antibody diversity analysis revealed immunodominant anti

11 permutation contributes to the generation of antibody diversity and is strongly associated with the m

12 ficity suggest new mechanisms for generating antibody diversity and polyreactivity (multispecificity)

13 DNA sequence preferences upon generation of antibody diversity, and the results have implications fo

14 inefficient, haphazard deamination produces antibody diversity associated with AID.

15 We report here that, in the case of antibodies, diversity at one of these regions, CDR3 of t

16 ene may not merely be a sequence restricting antibody diversity, but is potentially a novel receptor

17 Antibody diversity creates an immunoregulatory challenge

18 ogical processes including the generation of antibody diversity, DNA replication in a number of virus

19 The origin of antibody diversity has intrigued scientists for nearly a

20 prehensive, chip-based method to display the antibody diversity in an individual on peptide arrays.

21 chain 3, providing a unique perspective into antibody diversity in antigen recognition.

22 uced deoxycytidine deaminase (AID) generates antibody diversity in B cells by initiating somatic hype

23 s switching is crucial for the generation of antibody diversity in humoral immunity and, when deregul

24 y to rearrange the germ-line DNA to generate antibody diversity is an essential prerequisite for the

25 Our results suggest that antibody diversity is not limited by the sequences encod

26 Antibody diversity occurs randomly as B cells recombine

27 gnature technology is unbiased in displaying antibody diversity relative to natural sequence space, a

28 The antibody diversity required to achieve this is believed

29 ibody variable and switch regions, promoting antibody diversity through somatic hypermutation or clas

30 Increased antibody diversity to seasonal influenza viruses was ass

31 two mutagenic DNA processes used to generate antibody diversity via the B-cell mutator protein activa

32 preserve extracellular epitopes and optimize antibody diversity, we generated monoclonal antibodies t

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