ライフサイエンスコーパス: antibody specificity

1 a with protein data base searches based upon antibody specificity.

2 ody screening helped determine the patient's antibody specificity.

3 bands at 1080 and 990 cm-1 regardless of the antibody specificity.

4 t such regions form the core of both TCR and antibody specificity.

5 ng how TRIM21 achieves such remarkable broad antibody specificity.

6 ype and Caspr2-null mice were used to assess antibody specificity.

7 tide using weak and stringent selections for antibody specificity.

8 ts, a phenomenon viewed as dependent only on antibody specificity.

9 us sera were also examined for comparison of antibody specificities.

10 Fine epitope mapping revealed differences in antibody specificities.

11 ted sera, indicating additional neutralizing antibody specificities.

12 d healthy donors' global peptide profiles of antibody specificities.

13 ous virion capture index (IVCI) of different antibody specificities.

14 unoglobulin light chains and, therefore, two antibody specificities.

15 lization breadth was mediated by two or more antibody specificities.

16 IV-1 envelope immunogens do not induce these antibody specificities.

17 ely autoimmune, 10 with limbic encephalitis (antibody specificity: 5 LGI1, 1 contactin2, 2 negative,

18 infected children (62 percent) acquired new antibody specificities against glycoprotein H, as compar

19 The appearance of new antibody specificity against 1 of 4 polymorphic epitopes

20 Antibody specificity against TPH1 and TPH2 is retained a

21 from unmodified urine; furthermore, capture antibody specificity allows the probes to be multiplexed

22 This study further suggests that HLA antibody specificity analysis is a more useful clinical

23 the unbiased discovery of disease-associated antibody specificities and peptide reagents for their de

24 ions of gp120 conformations, each defined by antibody specificities and structural requirements of th

25 ese bispecific IgGs display features of both antibody specificities and, in some cases, display impro

26 on based on flow cytometric determination of antibody specificity and 10 underwent prospective crossm

27 antibody incubation times, while maintaining antibody specificity and activity toward target antigen.

28 subsequent clonal selection increase antigen-antibody specificity and binding energy.

29 report that this method can enhance antigen-antibody specificity and can improve the utility of some

30 No correlation was detected between antibody specificity and clinical phenotype.

31 In turn, this surface determines antibody specificity and cross-reactivity, which are imp

32 nd may provide a general strategy for tuning antibody specificity and cross-reactivity.

33 Antibody specificity and diversity is generated in B cel

34 The immunoconjugate preserved both antibody specificity and drug cytotoxicity.

35 However, the influences of antibody specificity and exposure levels on VAbeta and m

36 genic modifications that selectively refocus antibody specificity and improves induction of NAbs, and

37 Technical considerations, including antibody specificity and lability of phosphoepitopes, ar

38 Immunoblot analysis was performed to verify antibody specificity and the presence of Ngb and Cygb in

39 Antibody specificity and titer were defined by a microne

40 ltage-gated potassium channel (VGKC) complex antibody specificities, and central nervous system local

41 The phenotype, antibody specificity, and gene expression profile of the

42 emonstrated a virtual absence of this potent antibody specificity, and work by others suggests that t

43 in histogram architecture suggesting loss of antibody specificity; and one patient had a fourfold dec

44 However, these antibody specificities are rare, are not induced by Env

45 This study demonstrates that patterns of antibody specificity are remarkably stable in this patie

46 hese results support in silico CDR design of antibody specificity as an emerging antibody engineering

47 e surface of nonspherical particles enhances antibody specificity as well as avidity toward their tar

48 Antibody specificities assigned by the C1q- and C4d-Lumi

49 A general strategy to identify serum antibody specificities associated with a given disease s

50 esents the ideal format for an assay to test antibody specificity, because it allows the simultaneous

51 Clinical presentations, anti-CASPR2 antibodies specificities, brain magnetic resonance imagi

52 been proposed as one way to modify unwanted antibody specificities, but analysis of this mechanism h

53 B lymphocytes produce diverse antibody specificities by "randomly" assembling antibody

54 ntification of human leukocyte antigen (HLA) antibody specificities by flow cytometry.

55 x in sera of patients with SSc and confirmed antibody specificity by immunoprecipitation, reverse tra

56 parameters such as the amount of input DNA, antibody specificity, ChIP enrichment and sequencing dep

57 It takes advantage of antibody specificity combined with a pattern recognition

58 Three antibody specificities correlated with susceptibility (o

59 ot be excluded from transplantation based on antibody specificities determined by virtual crossmatch

60 Antibody specificity determines whether a B cell express

61 xhibited a definite acquisition of different antibody specificities during the monitoring.

62 d to the interior of leukemia cells based on antibody specificity for cell surface target antigens.

63 red to the interior of cancer cells based on antibody specificity for cell-surface target antigens.

64 We hypothesized that antibody specificity for deposited plaque was critical f

65 It is difficult to assign antibody specificity for highly sensitized patients usin

66 Antibody specificity has been confirmed by immunoassay,

67 relationships with potassium channel subunit antibody specificities have been unclear.

68 comprising more than 10(9) functional human antibody specificities in Fab format, we have been able

69 dentified a 78 to 100% agreement between the antibody specificities in GCF and those in serum.

70 current study, we analyzed the difference in antibody specificities in rabbit sera elicited by these

71 Furthermore, the antibody specificities in serum appear to reflect genera

72 ene recombination occurs, which often alters antibody specificity in a process called receptor editin

73 Since ELISA does not assure antibody specificity in chromatin immunoprecipitation, w

74 study clinical correlation with antigen and antibody specificity, in autoimmunity.

75 To evaluate antibody specificities induced by simian immunodeficienc

76 A central dogma in immunology is that antibody specificity is a function of the variable (V) r

77 While antibody specificity is crucial for neutralization, othe

78 confounding antigens, the assignment of HLA antibody specificity is difficult in highly sensitized p

79 erent analytes shows that the high degree of antibody specificity is not affected by PIT nor is it by

80 A central dogma in immunology is that antibody specificity is solely the result of variable (V

81 Thus, 2 or 3 antibody specificities may prevent infection by most HIV

82 evidence that a particular antiphospholipid antibody specificity may contribute to in vivo thrombosi

83 iter or specificity, the number of different antibody specificities, or whether or not the target ant

84 Our data demonstrate that antibody specificity plays an important role in the regu

85 IV-1, we have characterized the neutralizing antibody specificities present in the sera of three asym

86 vidual or multiple Pmp subtypes and that the antibody specificity profile varies between patients.

87 Different profiles of antibody specificities provide insight into the mechanis

88 Antibody specificity repertoires were determined by iden

89 analysis revealed the principal neutralizing antibody specificities that are cross-reactive for VACV,

90 Deciphering antibody specificities that constrain human immunodefici

91 neutralize diverse strains of HIV-1, but the antibody specificities that mediate this broad neutraliz

92 ast, there has been less systematic study of antibody specificities that must rely mainly or exclusiv

93 These data indicate the diversity of antibody specificities that target the glycan-V3 site.

94 lts, along with the new broadly neutralizing antibody specificities, the role for other antibody func

95 While the selectivity is based on antibody specificity, the lytic attack is triggered by F

96 with regard to different classes of assays, antibody specificities, thresholds, test variations, and

97 ved between classes of immunoassays, type of antibody specificity, thresholds, application of confirm

98 Antibody specificities to non-donor-specific antigens, o

99 ellular and humoral immunity by bridging the antibody specificity to effector cells.

100 nce interference and eliminates the need for antibody specificity to methylated lysines.

101 of AHI subjects, and compared the levels and antibody specificity to those in chronic infection.

102 Confirmation of antibody specificity was also performed by specific immu

103 Antibody specificity was analyzed by ELISA.

104 Antibody specificity was assessed by a competitive enzym

105 Antibody specificity was assessed by using Western analy

106 Antibody specificity was confirmed by (1) the detection

107 Antibody specificity was confirmed by flow cytometry, im

108 Antibody specificity was confirmed by the cell surface s

109 Antibody specificity was confirmed by the positive stain

110 Antibody specificity was defined by a combination of cyt

111 Antibody specificity was demonstrated upon identifying,

112 HGF and HGF (c-met) receptor monoclonal antibody specificity was demonstrated with fluorescent a

113 Since exposure to this antibody specificity was observed with a similar frequen

114 Antibody specificity was tested by preadsorption of the

115 Protein expression was measured by IHC, and antibody specificity was validated by Western blotting.

116 on was measured by immunohistochemistry, and antibody specificity was validated by Western blotting.

117 The antibody specificity was verified by immunoblotting and

118 nables precise determination of HLA-specific antibody specificity, was compared to prospective crossm

119 To define the antibody specificities, we looked for binding of serum a

120 impact of somatic hypermutation (SHM) on CLL antibody specificity, we cloned and expressed in vitro r

121 k-out mice as negative controls to establish antibody specificity, we show that these relatively smal

122 Antibody specificities were determined by performing imm

123 or the observed outcomes, global profiles of antibody specificities were determined.

124 However, antibody specificities were more commonly against self t

125 Changes in antibody specificity were associated with changes in bio

126 the host immunoglobulin (Ig) locus to evolve antibody specificity, whereas its close relative, APOBEC

127 phabeta alleles both for donor typing and as antibody specificities, which will lead to better repres

128 e a successful attempt to generate a desired antibody specificity, which was not present in the anima

129 assay is biased toward the detection of some antibody specificities while disfavoring others.

130 imultaneous detection of a broad spectrum of antibody specificities with as little as a few microlite

131 lar-weight forms of Delta123 elicit distinct antibody specificities with potent and broad neutralizin

132 Broadening antibody specificity without compromising affinity shoul

133 ion and a pseudotype assay that could assess antibody specificity without the need for high-level bio