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4 we measured total levels of immunoglobulin G antibodies to 5 PvDBP variants and used a functional in
5 intraperitoneal administration of a blocking antibody to 6 week-old female NOD/ShiLtJ mice repeatedly
7 ysium using an immunofluorescence assay, and antibodies to a deamidated gliadine peptide using an imm
8 e negative, eight specimens had neutralizing antibodies to a flavivirus (unable to be identified), an
10 Covalently binding an alpha-amylase specific antibody to a polyaniline (PANI) layer and controlling d
11 oximity-based labeling approach that uses an antibody to a target antigen to guide biotin deposition
14 he structure of the HCDR3, similar to bovine antibodies, to aid in recognition of a cluster of conser
23 e observed for recipients with pretransplant antibodies to AT1R (P = 0.19) and ETAR (P = 0.32), but d
24 enters between 2011 and 2013 were tested for antibodies to AT1R and ETAR by the enzyme-linked immunos
25 ponezumab, an anti-amyloid-beta40 selective antibody, to attenuate amyloid-beta accrual in cerebral
27 ants have the potential to allow therapeutic antibodies to be produced in virtually any expression sy
28 ntary binding region on all three monoclonal antibodies to be the CDR H3 loop of the Fab region, and
30 by 2 hours and was detected by an antiapo(a) antibody to be localized to Rab5-positive early endosome
32 ot only could enable the use of radiolabeled antibodies to become a common practice, but also could s
34 espite a wealth of activating and inhibitory antibodies to beta1 integrins, the conformational states
37 Here we report studies using a monoclonal antibody to block IFN-alpha/beta receptor (IFNAR) signal
39 llustrate the increased negative impact when antibodies to both HLA and non-HLA antigens are present
40 odies to site VIII competed for binding with antibodies to both of those adjacent neutralizing sites.
41 cline of maternally derived immunoglobulin G antibody to both the EBV viral capsid antigen and EBV nu
42 complex tubulointerstitial nephritis due to antibodies to brush border antigens of the proximal tubu
43 group of a phase 2 trial testing monoclonal antibodies to C. difficile toxins A and B for preventing
44 We measured the ability of vaccine-induced antibodies to capture infectious simian immunodeficiency
45 f the antibody, is biodegradable, and has an antibody to carrier mass ratio of 13, which is greater t
54 tial therapeutic usefulness of high-affinity antibodies to cell wall carbohydrates is unquestioned, h
56 d (iii) reveal that neutralization of CMV by antibodies to certain epitopes in gH or gH/gL is both st
57 s were collected on filter paper to test for antibodies to Chlamydia trachomatis pgp3 using a multipl
59 eloped antibodies and T cells to PAD and IgG antibodies to citrullinated fibrinogen peptides, in the
63 ple sclerosis (MS), we administered blocking antibody to CLEC12A that significantly ameliorated disea
65 ts novel therapeutic approaches that include antibodies to common gamma cytokines, inhibitors of cyto
66 ne complication of heparin therapy caused by antibodies to complexes of platelet factor 4 (PF4) and h
67 nd folding and the induction of neutralizing antibodies to conformational B cell epitopes of MSP119 H
69 protection and the failure of a neutralizing antibody to correlate with protection against dengue vir
71 logues are being attached to tumor-targeting antibodies to create antibody-drug conjugates (ADCs), a
72 es, including the ability of vaccine-induced antibodies to cross-neutralize the field strains of HCMV
78 ells can be isolated from the ovary using an antibody to DDX4, there is no good in silico modelling t
79 ted the capacity of anti-receptor monoclonal antibodies to deliver vaccine components to skin DC subs
80 ly blocked the binding of a non-neutralizing antibody to Delta123, while having reduced ability to bl
82 the therapeutic activity of human monoclonal antibodies to DENV EDE for their ability to control ZIKV
83 e present study used rituximab, an anti-CD20 antibody, to deplete B cells in M. tuberculosis-infected
85 flow and mass cytometry, Abseq uses specific antibodies to detect epitopes of interest; however, unli
88 longitudinal cohort of 300 Kenyan children, antibodies to different AMA1 and MSP2 alleles of merozoi
90 ity of agonists, and the inherent failure of antibodies to differentiate between the large number of
91 ttenuated by metalloproteinase inhibitors or antibodies to disintegrin metalloproteinase 8 (ADAM8), a
95 blocking peptide, as well as a neutralizing antibody to E-cadherin, works synergistically with ioniz
96 ndwich ELISA and the specific recognition of antibody to E. coli O157:H7, the sensitive detection of
101 onstructed by immobilization of NGAL capture antibodies to electropolymerized aniline deposited on to
103 on synergizes with tumor-specific monoclonal antibodies to eliminate human tumor xenografts by enhanc
104 when the mice were treated with a monoclonal antibody to eliminate residual granulocyte activity.
105 require the use of (surrogate) mouse or rat antibodies to enable optimal interactions with murine ef
106 process in which B lymphocytes evolve potent antibodies to encountered antigens and generate immune m
107 Furthermore, we assessed the ability of the antibody to enter the tumor by in silico and in vivo met
112 aporin was conjugated to a Siglec-8-specific antibody to examine the targeting of an agent to these c
121 humans and with glycan-binding proteins and antibodies to gather information about the structures of
122 tiumlike structures was impaired not only by antibodies to gB or gH/gL but also by antibodies to the
129 antibody to HBsAg status, serial changes in antibody to HBsAg levels, and donor serology, were not a
131 ther clinical parameters, including baseline antibody to HBsAg status, serial changes in antibody to
135 administration of glucagon receptor-blocking antibody to healthy individuals increased plasma glucago
136 erval [CI] 9.4%-19%) in 388 patients who had antibodies to hepatitis B core antigen only versus 5.0%
137 ionalized persons age 6 years and older for: antibody to hepatitis B core antigen (anti-HBc), indicat
138 epatitis B surface antigen (HBsAg)-negative, antibody to hepatitis B core antigen (anti-HBc)-positive
140 should screen (hepatitis B surface antigen, antibody to hepatitis B core antigen, and antibody to he
141 use of conflicting studies about whether the antibody to hepatitis B surface antigen (anti-HBs) prote
142 dicative of chronic (current) infection; and antibody to hepatitis B surface antigen (anti-HBs), indi
144 n, antibody to hepatitis B core antigen, and antibody to hepatitis B surface antigen) for HBV in high
145 ore, this study investigated how preexisting antibodies to historical influenza viruses influenced HA
148 animals have shown that broadly neutralizing antibodies to HIV-1 can prevent infection, suggesting th
149 3BNC117 is a broad and potent neutralizing antibody to HIV-1 that targets the CD4 binding site on t
151 ox models revealed that men with circulating antibodies to HPV-6, -11, -16, or -18 were not less like
153 ese IVIG fragments, nor agonistic monoclonal antibodies to human Fas or Siglec-9 affected the viabili
155 antagonism mechanism by which the binding of antibodies to HVR1 blocks the binding and activity of br
156 ity, we used a panel of broadly neutralizing antibodies to identify the immunogenic sites of a domina
157 These proteins complement immune cells and antibodies to identify, tag, destroy, and eliminate path
158 antibodies to merozoites did not decline and antibodies to IE surface antigens expressing virulent ph
159 universal; some key functional responses and antibodies to IEs were better maintained and these may c
160 atients with metastatic disease had elevated antibodies to IGFBP2, p53, HER2-ICD, HER2-ECD, and CEA,
162 ta expressing murine IL-12 (G47Delta-mIL12), antibodies to immune checkpoints (CTLA-4, PD-1, PD-L1),
163 vantage of the selectivity of the monoclonal antibody to increase the efficacy of the chemotherapeuti
164 e malaria tend to be more seroprevalent than antibodies to infected erythrocytes from children with n
165 ated that in areas where malaria is endemic, antibodies to infected erythrocytes from children with s
166 nvasion (ISI) assay to assess the ability of antibodies to inhibit sporozoite infection of hepatocyte
167 KI, we utilized a specific function-blocking antibody to inhibit alphavbeta5 in a rat model of renal
168 dition of nivolumab (anti-programmed death-1 antibody) to ipilimumab (anti-cytotoxic T-cell lymphocyt
171 s reactivation (BK viremia or JC viruria) on antibodies to kidney-specific self-antigens is unknown.
173 ation of FRET donor and acceptor anti-PrP(C) antibodies to living cells yielded a measure of PrP(C) s
174 , administering agonist anti-CD40 monoclonal antibody to LNG-treated mice at 1 dpi restored lung T ce
177 n the spinal cord using a saporin-conjugated antibody to Mac1, we demonstrate a causal role for micro
180 e phenomenon for the ability of neutralizing antibodies to mediate protective effects in vivo is unde
184 tic production of IgM and class-switched IgG antibodies to microbial capsular polysaccharides, which
185 Furthermore, naturally occurring catalytic antibodies to microbial determinants have been correlate
187 te the utility of employing an anti-idiotype antibody to monitor a patient's specific immune response
189 at vaccination elicited functional antiviral antibodies to multiple neutralizing sites in rhesus maca
190 important insights on the efficacy of human antibodies to Mycobacterium tuberculosis and on how func
191 iments using antibody transfer indicate that antibodies to NA have an important role in protection.
196 ltered DC function had greater production of antibody to P. gingivalis, greater IL-12 expression, and
197 gests that administration of CTLA-4 blocking antibodies to patients who express high levels of CTLA-4
198 ion; (2) immunoprecipitation of plasma using antibodies to PCSK9 and immunodetection of apo(a); (3) E
202 , antibody to filamentous hemagglutinin, and antibody to pertactin were measured in maternal blood be
206 tal reports (P < 0.001) and reports with IgE antibodies to PHO (P = 0.008) and SUX (P = 0.001) at tim
207 sponses to TNP-Ficoll, production of natural antibodies to phosphocholine, and survival after intrana
209 ining malaria transmission on maintenance of antibodies to Plasmodium falciparum merozoite antigens a
210 secreting cells that cause the deposition of antibodies to polymorphic recipient antigens (ie, alloan
213 t for glycosylation remodeling of monoclonal antibodies to produce homogeneous intact antibody glycof
216 he FOURIER trial of evolocumab, a monoclonal antibody to proprotein convertase subtilisin-kexin type
218 ted effector cell population cooperates with antibody to protect against genital chlamydia and establ
220 lass correlation coefficients (ICCs) between antibodies to quantify interassay variability for PD-L1
222 s study, the ability of different monoclonal antibodies to recognize, inhibit, or activate mouse BAFF
223 ric mean concentrations (GMCs) of cord blood antibodies to recombinant pertussis toxin (PT) and filam
224 al residues that can be targeted by blocking antibody to reduce infection, and determines that it bin
226 odies competitively inhibited binding of IgE antibodies to Rhi o 1 up to 70% and suppressed allergen-
227 s the most predominant antibody subclass and antibodies to rLinB-13 did not cross react with Lu. long
228 d that administration of cis P-tau targeting antibody to rodents reduces or delays pathological featu
229 body complexes after binding of RSV-specific antibodies to RSV antigens expressed on the surface of i
230 stvaccination concentrations of neutralizing antibodies to RV5 were negatively correlated with prevac
231 d when her serum sample was found to contain antibodies to S-arrestin, a retinal protein and potent c
235 herapy and combine the ability of monoclonal antibodies to specifically target tumour cells with the
236 type 2 inflammatory patterns, including IgE antibodies to staphylococcal superantigens; several stud
238 owing abortion in a majority of the animals, antibodies to surface proteins persisted beyond the dura
239 able, from no severe effects attributable to antibodies, to sustained reticulocytopenia, to near-fata
242 of the Hex nanocarrier to deliver functional antibodies to the cytosol by employing anti-beta-tubulin
246 st likely has to induce broadly neutralizing antibodies to the HIV-1 envelope glycoprotein (Env) spik
247 We also demonstrate multiplexed detection of antibodies to the HPV16 proteins E2, E6, and E7, which a
248 ercome this challenge, we generated specific antibodies to the mouse oxytocin receptor and examined r
249 and their nationwide registers to search for antibodies to the N-methyl-D-aspartate receptor (NMDAR)
250 th myasthenia gravis (MG) without detectable antibodies to the nicotinic acetylcholine receptor (AChR
252 nly by antibodies to gB or gH/gL but also by antibodies to the pentamer, suggesting a potential role
257 tralizing activity of serum immunoglobulin G antibodies to the RSV prefusion (pre-F), postfusion (pos
258 ) we applied site-specific immobilization of antibodies to the solid surface that avoids loss of biol
263 ions result from the specific binding of the antibody to the beta-subunit of Fsh to block its action.
264 f a T-cell-depleting anti-CD8beta monoclonal antibody to the controller animals led to a specific dec
265 ent of C57BL/6 or NOD mice with a monoclonal antibody to the CSF-1 receptor resulted in depletion of
269 ive (18)F-FDG PET to monitor therapy with an antibody to the insulinlike growth factor 1 receptor (IG
274 ntibody-binding behavior, but delivered more antibodies to their cytosolic targets at a faster rate.
276 ely bind fungal cells and recruit endogenous antibodies to their surfaces, resulting in immune-mediat
280 yroid autoimmunity refers to the presence of antibodies to thyroperoxidase or thyroglobulin, or thyro
281 d by these cells, and addition of anti-NKp46 antibodies to TIL cultures abrogated the ability of thes
282 ian time period of 10 years and analyzed for antibodies to tissue transglutaminase (anti-TG2A) using
283 easure serum endomysial antibodies (EMA) and antibodies to tissue transglutaminase (tTG) were develop
284 administration, or systemic injections of an antibody to TNF before or during sensitization and chall
288 ical rationale for the use of ADCC-optimized antibodies to treat tumors harboring this EGFR isoform.
291 veloped by IDEXX laboratories, which detects antibodies to two M. bovis proteins, MPB70 and MPB83.
292 chain reaction (PCR)- and the prevalence of antibodies to two P. falciparum antigens (MSP-1, AMA-1).
293 Whether RAS activation, mucosal ILCs and antibodies to V2 are also important hallmarks of HIV-vac
294 endpoint was the change from baseline in IgG antibody to varicella-zoster virus-specific glycoprotein
295 , delivery of an isoform-specific monoclonal antibody to VEGF165b versus control antibody enhanced pe
296 rodiagnosis accomplished by the detection of antibodies to virulence-associated antigens such as CPAF
297 etected on viruses following incubation with antibodies to VZV gE ( approximately 100%), Rab11 (50%),
298 2 and Skerritt monoclonal and two polyclonal antibodies to well-defined gluten protein types (GPT) is
300 three ELISAs for the detection of IgM class antibodies to ZIKV, including the Centers for Disease Co
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