ライフサイエンスコーパス: anticonvulsant

1 6) combined with atropine and on occasion an anticonvulsant.

2 ssion of neuropeptide Y (NPY), an endogenous anticonvulsant.

3 pilocarpine alone, suggesting that SNC80 was anticonvulsant.

4 is a convulsant, but the R-enantiomer is an anticonvulsant.

5 convulsant, whereas R-mTFD-MPPB acted as an anticonvulsant.

6 py includes tricyclic antidepressants and an anticonvulsant.

7 interneurons essentially insensitive to this anticonvulsant.

8 ccupied by traditional local anesthetics and anticonvulsants.

9 nce seizure generation and responsiveness to anticonvulsants.

10 acting drugs, including antidepressants and anticonvulsants.

11 t spontaneous convulsions (>1 per hour) with anticonvulsants.

12 g-sensitive (BS) mutants as a tool to screen anticonvulsants.

13 lopmental quotient (DQ) > 30 did not require anticonvulsants.

14 SSRIs and SNRIs; -0.91, -1.23 to -0.60), and anticonvulsants (-0.81, -1.36 to -0.28).

15 small compounds: three transplant drugs, an anticonvulsant, a steroid, an anticancer drug, and an an

16 Adenosine is a potent anticonvulsant acting on excitatory synapses through A1

17 We tested leptin's anticonvulsant action in 2 rodent seizure models by dire

18 n of Cl- transport by bumetanide enables the anticonvulsant action of phenobarbital in immature brain

19 efore tested whether bumetanide enhances the anticonvulsant action of phenobarbital in the neonatal b

20 y gamma-aminobutyric acid receptors and have anticonvulsant action.

21 ory amino acid release may contribute to the anticonvulsant actions of (RS)-3,4-DCPG, it does not rep

22 Acute anticonvulsant actions of 2DG were assessed in vitro in

23 In contrast to the anticonvulsant actions of the 3,4-DCPGs, no evidence was

24 bility to promote anxiolytic, analgesic, and anticonvulsant actions.

25 odents, select compounds exhibited excellent anticonvulsant activities and protective indices (PI=TD5

26 compound class B) exhibited a broad range of anticonvulsant activities in animal models, and in the m

27 drophobic groups and still retain pronounced anticonvulsant activities in rodents in the MES seizure

28 operties of the modified peptides, but their anticonvulsant activities varied substantially and were

29 ileptic drugs (AEDs) that exhibit pronounced anticonvulsant activities.

30 e model of epilepsy and demonstrated in vivo anticonvulsant activity (ED(50) = 8.4 mg/kg) in the mous

31 Analogue 1 also had potent oral anticonvulsant activity against maximal electroshock (ME

32 D, (2R,3R)-SPD, and racemic-SPD have similar anticonvulsant activity and a PK profile that are better

33 f these derivatives were evaluated for their anticonvulsant activity and displayed effective seizure

34 ctivity of these compounds is related to the anticonvulsant activity and implicate neural activity in

35 eospecific comparative pharmacodynamics (PD, anticonvulsant activity and teratogenicity) and pharmaco

36 vation in other neuronal subtypes would have anticonvulsant activity and that intranasal leptin deliv

37 tereoisomers of compound 33 revealed greater anticonvulsant activity by R(+)-33 enantiomer in both ME

38 in vivo effects in assays for locomotion and anticonvulsant activity correlated fairly well with its

39 F1,6BP had dose-dependent anticonvulsant activity in all three models, whereas VPA

40 ained agonist activity, and exhibited potent anticonvulsant activity in mice following intraperitonea

41 oxy-5alpha-pregnan-20-one), exhibit enhanced anticonvulsant activity in perimenstrual catamenial epil

42 This compound exhibited excellent anticonvulsant activity in rodents against audiogenic, e

43 Compound 4 exhibited excellent anticonvulsant activity in rodents against audiogenic, e

44 Compound 33 showed the highest anticonvulsant activity in these models (ED50 MES = 79.5

45 The anticonvulsant activity loss that accompanied introducti

46 ock in the glycolytic pathway, abolished the anticonvulsant activity of 2-DG in the pilocarpine model

47 The anticonvulsant activity of 6 and 7 resided primarily in

48 The anticonvulsant activity of F1,6BP was determined in rat

49 Because the anticonvulsant activity of galanin is mediated by the re

50 Prior work demonstrated anticonvulsant activity of SGE-516 in acute seizure assa

51 logical test that was employed to assess the anticonvulsant activity of the training set compounds; o

52 uld represent a key mechanism underlying the anticonvulsant activity of topiramate.

53 seizure protection in mice, and like (R)-2, anticonvulsant activity principally resided in the (R)-s

54 SPD stereoisomers' anticonvulsant activity was comparatively evaluated in s

55 of 19 carbamates was synthesized, and their anticonvulsant activity was comparatively evaluated in t

56 Significant anticonvulsant activity with little or no motor impairme

57 ave oral general anesthetic activity, potent anticonvulsant activity, and minimal hemodynamic effects

58 e relationship between the LAA structure and anticonvulsant activity, orthogonally protected LAAs wer

59 und N(6) suitable for an A(1)AR agonist with anticonvulsant activity.

60 e thresholds dose-dependently, indicative of anticonvulsant activity.

61 osphate pathway, it was hypothesized to have anticonvulsant activity.

62 es, i.e., 3 (a-e) and 5 (a-e) and evaluated, anticonvulsant activity.

63 -9, 10a-i, 11a, 11b, 12) and evaluated their anticonvulsant activity.

64 pigenetic function of the brain's endogenous anticonvulsant adenosine, showing that this compound ind

65 Adults not taking enzyme-inducing anticonvulsants after resection or biopsy of GBM were tr

66 includes administration of a benzodiazepine anticonvulsant agent (e.g. diazepam) and/or physical coo

67 YNA), a well established neuroprotective and anticonvulsant agent, involved in synaptic transmission

68 have recently been shown to be effective new anticonvulsant agents in a rodent model of epilepsy, wit

69 tegy for the first time for the discovery of anticonvulsant agents in the Maybridge and National Canc

70 Forty-eight anticonvulsant agents of the functionalized amino acid (

71 din-1-yl)butanamides as potential new hybrid anticonvulsant agents was synthesized.

72 psychotropic classes (e.g., antidepressants, anticonvulsants), although they may be safer options.

73 ues in patients treated with enzyme-inducing anticonvulsants, although this did not reach statistical

74 Total synthesis of anticonvulsant amino acid, lacosamide, is reported.

75 methyl)-5-methylhexanoic acid, Lyrica] is an anticonvulsant and analgesic medication that is both str

76 TS is 2 orders of magnitude more potent than anticonvulsant and antiarrhythmic sodium channel blocker

77 idely prescribed short chain fatty acid with anticonvulsant and anticancer properties, remains poorly

78 GABAergic involvement in ECT's mechanism of anticonvulsant and antidepressant actions.

79 Our results show that 2DG has anticonvulsant and antiepileptic properties, suggesting

80 The glycolytic inhibitor 2DG exerts acute anticonvulsant and chronic antiepileptic actions, and ha

81 arget therapies are unlikely to provide both anticonvulsant and disease-modifying effects.

82 d by valproic acid (VPA), a mood-stabilizer, anticonvulsant and histone deacetylase (HDAC) inhibitor,

83 ncreasing levels of adenosine, an endogenous anticonvulsant and neuroprotective molecule, might help

84 therapy may be helpful, in terms of both an anticonvulsant and possibly a neuroprotective effect.

85 uggests that targeting the P2X7 receptor has anticonvulsant and possibly disease-modifying effects in

86 naling and are thus targeted by a variety of anticonvulsant and relaxant drugs.

87 Evidence supports the use of specific anticonvulsants and antidepressants for pain management

88 ly important compounds, including diuretics, anticonvulsants and antidepressants, many of which have

89 drugs with a focus on the controlled use of anticonvulsants and steroids.

90 allosterically modulated by the anxiolytic, anticonvulsant, and sedative-hypnotic benzodiazepines.

91 ceptor are important anesthetics, sedatives, anticonvulsants, and anxiolytics.

92 es occur frequently, are often refractory to anticonvulsants, and are associated with considerable mo

93 Clinicians should utilize omega-3, anticonvulsants, and atypical antipsychotic agents in tr

94 mptomatic treatment with corticosteroids and anticonvulsants, and definitive therapy in the form of w

95 inhibitors, cinchona alkaloids, antibiotics, anticonvulsants, and heparin.

96 neurological symptoms, with gabapentin-type anticonvulsants, and is among the first in nonepileptic

97 hotics for schizophrenia and antipsychotics, anticonvulsants, and lithium for bipolar disorder.

98 Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-ga

99 reatments include tricyclic antidepressants, anticonvulsants, and opioids, depending on the severity

100 ivity was comparatively evaluated in several anticonvulsant animal models including the benzodiazepin

101 ntral and the peripheral nervous systems has anticonvulsant, anti-inflammatory, and analgesic propert

102 utic drugs and supportive-care drugs-such as anticonvulsants, antiemetics, uric-acid-lowering compoun

103 17-3.81; P for trend < .001), whereas use of anticonvulsants, antipsychotics, or antidepressants was

104 olam, an anesthetic BDZ, with clonazepam, an anticonvulsant/anxiolytic BDZ that activates CBRs select

105 the KCNQ2-5 channel activator retigabine, an anticonvulsant approved by the U.S. Food and Drug Admini

106 Therefore, new and more effective anticonvulsants are continually sought after to combat t

107 These anticonvulsants are neutral, in contrast to the mostly p

108 Broad-spectrum anticonvulsants are of considerable interest as antiepil

109 on as antinociceptive, antiinflammatory, and anticonvulsant as well as antiinfective agents.

110 Maintenance treatment with lithium or anticonvulsants as practiced in modern care is associate

111 PURPOSE OF REVIEW: Despite myriad anticonvulsants available and in various stages of devel

112 s to specific treatments, including sedative anticonvulsants (barbiturates and benzodiazepines) and E

113 ney disease, or diabetes and subjects taking anticonvulsants, barbiturates, or steroids.

114 de: antidepressants, anti-adrenergic agents, anticonvulsants, benzodiazepines, atypical antipsychotic

115 dditional commonly used Na(+) channel-acting anticonvulsants, both in control and epileptic animals.

116 The anticonvulsant carbamazepine 1 is associated with advers

117 ies and other risk factors, among individual anticonvulsants compared with topiramate and secondarily

118 igation of neuroactive steroids as potential anticonvulsant compounds for refractory epilepsies.

119 dal-rostral developmental pattern, GABAergic anticonvulsant compounds inhibit motor manifestations of

120 alanin analogues yielded systemically active anticonvulsant compounds.

121 We report that carbamazepine, an anticonvulsant, corrects the trafficking defects of muta

122 Valproate is an important anticonvulsant currently in clinical use for the treatme

123 .80-3.42; P for trend < .001), as was use of anticonvulsants (definite CKD, 1-2 prescriptions: HR = 1

124 unds represent novel leads in the search for anticonvulsants devoid of sedative, ataxic, and amnestic

125 icus, which was decreased in severity by the anticonvulsant diazepam.

126 scussed in light of the effectiveness of the anticonvulsant drug gabapentin, which is a specific inhi

127 Ethosuximide (ETH), an anticonvulsant drug is used for the treatment of epilept

128 that are associated with the binding of the anticonvulsant drug Lamotrigine and batrachotoxin are al

129 ium-stimulated efflux was potentiated by the anticonvulsant drug retigabine (EC(50)=0.5 microM).

130 The effect of gabapentin, an anticonvulsant drug that is also effective in pain and a

131 on to die of their disease respond poorly to anticonvulsant drug therapy, suggesting a need for new t

132 condition can be induced without concomitant anticonvulsant drug treatment.

133 We have previously shown that the anticonvulsant drug valproate (VPA) depletes inositol by

134 This study focuses on carbamazepine, an anticonvulsant drug which is ubiquitously detected in re

135 id is a short branched fatty acid used as an anticonvulsant drug whose therapeutic action has been pr

136 the most cold sensitive was lamotrigine, an anticonvulsant drug.

137 We have, therefore, studied the effects of anticonvulsant drugs acting via use-dependent block of v

138 Many currently used anticonvulsant drugs are known to exert potent use-depen

139 In many epileptic patients, anticonvulsant drugs either fail adequately to control s

140 With an increasing number of anticonvulsant drugs it is likely that patients may not

141 The tricyclic anticonvulsant drugs phenytoin, carbamazepine, and lamot

142 ve agents, estrogens, progestins, sedatives, anticonvulsant drugs, or drugs that may form N-nitroso d

143 izures and can be refractory to conventional anticonvulsant drugs, suggesting an age-specific form of

144 in producing the mood-stabilizing effects of anticonvulsant drugs.

145 eses for the antimanic action of lithium and anticonvulsant drugs.

146 ful reduction of CNS excitability exerted by anticonvulsant drugs.

147 sed as local anesthetic, antiarrhythmic, and anticonvulsant drugs.

148 l rendered WSP mice less sensitive to ALLO's anticonvulsant effect and more sensitive to FIN's procon

149 terations in metabolism, as evident from the anticonvulsant effect of diets that reduce glucose utili

150 EtOH exposure, WSP mice were tolerant to the anticonvulsant effect of intra-hippocampal ALLO infusion

151 icacious than bumetanide in potentiating the anticonvulsant effect of phenobarbital.

152 The full anticonvulsant effect of the ketogenic diet (KD) can req

153 enous peptide ligand galanin exerts powerful anticonvulsant effect through activation of these two G

154 the pentose phosphate pathway, would have an anticonvulsant effect.

155 ologies in adolescent rats to understand its anticonvulsant effect.

156 of VPA-treated mice with retigabine induced anticonvulsant effects even when administered after seiz

157 ppress this pathway may be important for its anticonvulsant effects in AGS-kindled GEPR-9s, and this

158 -releasing hormone (TRH) is reported to have anticonvulsant effects in animal seizure models and cert

159 AP has enhanced anticonvulsant effects in fully kindled wild-type mice,

160 vestigated the potential neuroprotective and anticonvulsant effects of compounds acting on mGlu II re

161 citability are proposed to contribute to the anticonvulsant effects of LEV.

162 also showed a trend toward tolerance to the anticonvulsant effects of lorazepam.

163 Here, we report that the anticonvulsant effects of nonacute VPA treatment involve

164 e-induced seizure transiently eliminated the anticonvulsant effects of VPA.

165 pen receptor-suppressed M-channels, provided anticonvulsant effects only when administered prior to s

166 refractory depression, produces considerable anticonvulsant effects that may be related to increased

167 Anticonvulsant effects were observed in vivo with compou

168 ggest that cannabidiol could be exerting its anticonvulsant effects, at least in part, through its ac

169 Propofol and desflurane have reliable anticonvulsant effects, whereas remifentanil in larger d

170 The anticonvulsant efficacy of phenobarbital, bumetanide, an

171 data demonstrate that F1,6BP has significant anticonvulsant efficacy.

172 d in patients receiving p450 enzyme-inducing anticonvulsants (EIACs) by 73%, 47%, and 50%, respective

173 clohex-3-en-6-methyl-2-oxo-1-oate (E139), an anticonvulsant enaminone, has antinociceptive activity i

174 convulsant M-channel blocker linopirdine and anticonvulsant enhancer retigabine display increased and

175 aging or EEG), prophylactic antipyretics and anticonvulsants far outweigh their potential benefits.

176 Valproic acid (VPA) is a widely prescribed anticonvulsant for the treatment of epilepsy.

177 The anticonvulsant gabapentin is effective in reducing the s

178 h breast cancer, after she was placed on the anticonvulsant gabapentin.

179 Lacosamide, a recently approved anticonvulsant, has unique effects on sodium channels th

180 Although anticonvulsants have proven very helpful in treating sei

181 the brain and act as endogenous anxiolytic, anticonvulsant, hypnotic, and sedative agents, actions t

182 Lacosamide is an anticonvulsant hypothesized to enhance slow inactivation

183 emperature, allowed for the synthesis of the anticonvulsant ilepcimide with up to 96 % conversion.

184 ge underlying precipitant causes, administer anticonvulsants in rapid succession until seizures have

185 ation, and for prophylactic antipyretics and anticonvulsants, in the majority of children with simple

186 ampal infusion of ALLO (0.1 microg/side) was anticonvulsant, increasing the threshold dose of PTZ for

187 the most teratogenic of commonly prescribed anticonvulsants, increasing the risk in humans of major

188 tors cocaine and MK-801 [(+)-dizocilpine, an anticonvulsant] indicated they bind to a regulatory site

189 ds, acetaminophen, anti-inflammatory agents, anticonvulsants, ketamine, clonidine, mexiletine, antide

190 nctive therapy is sodium valproate (VPA), an anticonvulsant known to promote neurite outgrowth and in

191 t chemistries, were suspect-screened for the anticonvulsant lamotrigine (LMG), its metabolites, and r

192 The structurally different anticonvulsant lamotrigine and one of its derivatives ha

193 o change treatment to one of the noninducing anticonvulsants lamotrigine or levetiracetam.

194 class of selective KCNQ2/Q3 activators with anticonvulsant-like activity in experimental models of e

195 re antidepressants, atypical antipsychotics, anticonvulsants, lithium, and other medications used in

196 ior, in addition to concerns that the use of anticonvulsants may increase self-harm.

197 We propose an anticonvulsant mechanism of the KD involving mitochondri

198 romodulator adenosine is a potent endogenous anticonvulsant mechanism, which limits the extension of

199 Anticonvulsant mechanisms of the ketogenic diet remain i

200 There was no correlation with withdrawal of anticonvulsant medication, and death certificate informa

201 ved in two-thirds of cases by treatment with anticonvulsant medication, surgical resection, and/or ne

202 atus epilepticus in children, including both anticonvulsant medications and overall management approa

203 eviews suggest a role for antidepressant and anticonvulsant medications for neuropathic pain, but the

204 Administration mandated warning labeling for anticonvulsant medications regarding the increased risk

205 ons of the inhibition of the receptor by the anticonvulsant MK-801 [(+)-dizocilpine] and the abused d

206 was to determine whether zonisamide, another anticonvulsant mood stabilizer, as well as lithium, a mo

207 dicate the potential clinical utility of the anticonvulsant mood stabilizer, valproate, in bipolar di

208 We have recently reported that the anticonvulsant mood stabilizers (AMS), valproic acid, ca

209 Anticonvulsant mood stabilizers, e.g., valproic acid and

210 or possible clinical synergism of an APD and anticonvulsant mood-stabilizer in improving the cognitiv

211 Antipsychotic drugs (APD)s and anticonvulsant mood-stabilizers are now frequently used

212 g. clozapine and risperidone, as well as the anticonvulsant mood-stabilizers, valproic acid (VPA), zo

213 tabilizing agents but only those, which have anticonvulsant mood-stabilizing properties, increase DA

214 ts exposed to either lithium (n = 26,731) or anticonvulsants (n=420,959).

215 y was attributable to greater release of the anticonvulsant neuropeptide, neuropeptide Y (NPY).

216 Some drugs developed as anticonvulsants (notably, valproate and lamotrigine) hav

217 ds for chronic noncancer pain, compared with anticonvulsants or cyclic antidepressants, was associate

218 for long-acting opioids or either analgesic anticonvulsants or low-dose cyclic antidepressants (cont

219 but no cross-reactivity was seen with other anticonvulsants or structural analogs.

220 psychotics, combinations of antidepressants, anticonvulsants, or "other") for >/=60 consecutive days

221 in 297,620 new episodes of treatment with an anticonvulsant (overall median follow-up, 60 days).

222 ose of irinotecan was based on the patient's anticonvulsant: Patients taking enzyme-inducing antiepil

223 The widely used anticonvulsant pharmaceutical carbamazepine is recalcitr

224 We report that a barbiturate anticonvulsant, phenobarbital, alleviates the effect of

225 The anticonvulsant phenytoin has been reported to be an indu

226 , which was similar to that observed for the anticonvulsants phenytoin (slowly binds to the fast-inac

227 The widely prescribed anticonvulsants phenytoin and carbamazepine are potent i

228 s is a mechanistic demonstration of rational anticonvulsant polypharmacy.

229 By feeding the BS mutants a known anticonvulsant, potassium bromide, we have demonstrated

230 ibitors--duloxetine and milnacipran--and the anticonvulsant pregabalin are encouraging.

231 here was a small but significant increase in anticonvulsant prescriptions (rate, 0.117; 95% CI, 0.08-

232 The anticonvulsant profile of 4 suggests that it may be usef

233 Proconvulsant and anticonvulsant properties have been reported for virtual

234 evidence that glycine can have both pro- and anticonvulsant properties in various rodent models of ep

235 s well as lithium, a mood stabilizer without anticonvulsant properties, also increases prefrontal cor

236 In addition, some compounds exhibit anticonvulsant properties.

237 ntin is a structural analog of GABA that has anticonvulsant properties.

238 for assaying and testing new compounds with anticonvulsant properties.

239 n principal hippocampal neurons and displays anticonvulsant properties.

240 sttraumatic epilepsy and therefore long-term anticonvulsant prophylaxis is not recommended.

241 A key role for kappa opioids in anticonvulsant protection provides a framework for explo

242 In contrast, only the anticonvulsant R-enantiomer binds to the enhancing site

243 opionamide, (R)-1) is a low molecular weight anticonvulsant recently introduced in the United States

244 Conventional anticonvulsants reduce neuronal excitability through eff

245 Phenobarbital had insignificant anticonvulsant responses in the neocortex until NKCC1 wa

246 and limited human data suggest an important anticonvulsant role for opioid peptides and their recept

247 Consistent with an anticonvulsant role, the ketone body effect is larger fo

248 stitute of Neurological Disorders and Stroke Anticonvulsant Screening Program for seizure protection

249 This model also exhibited anticonvulsant sensitivity similar to in vivo models.

250 ng at very high rates, suggesting that these anticonvulsants should cause impaired GABAergic inhibiti

251 TCAs (SMD, -0.78 [CrI, -1.24 to -0.33]), and anticonvulsants (SMD, -0.67 [CrI, -0.97 to -0.37]) were

252 epinephrine reuptake inhibitors (SNRIs) than anticonvulsants (standardized mean difference [SMD], -0.

253 ation of action in the performed time course anticonvulsant studies, being nontoxic in subacute toxic

254 ng-term relapse prevention; the evidence for anticonvulsants such as divalproex and lamotrigine is le

255 lectroencephalographic response to GABAergic anticonvulsants such as phenobarbital and benzodiazepine

256 eclude the efficacy of widely used GABAergic anticonvulsants such as phenobarbital.

257 that SF0034 was a more potent and less toxic anticonvulsant than retigabine in rodents.

258 Retigabine is a recently approved anticonvulsant that acts by potentiating neuronal M-curr

259 disorder has been limited to vigabatrin, an anticonvulsant that blocks GABA transaminase.

260 Valproic acid is a widely used anticonvulsant that has recently been approved for stabi

261 CBZ) and oxcarbazepine (OXC) are widely used anticonvulsants that are extensively metabolized in the

262 activity in the cortex is not suppressed by anticonvulsants that block the transmission of seizure a

263 tribute to resistance of seizure activity to anticonvulsants that increase GABAergic function, and ma

264 two of which are approved for human use, are anticonvulsants that modulate neural activity.

265 Except for anticonvulsants, the adjusted risks for all individual c

266 des because of the increased availability of anticonvulsants, the ketogenic diet has re-emerged as a

267 s could point to molecular targets for novel anticonvulsant therapies.

268 potential use of K(v)7 openers as a targeted anticonvulsant therapy to improve developmental outcome

269 ides a starting point for the development of anticonvulsant therapy using the galanin R2 receptor as

270 ls; antidepressant tranylcypromine (2.15 A), anticonvulsant thioperamide (1.65 A), antifungal voricon

271 is to stop the seizures quickly enough with anticonvulsants to prevent brain damage.

272 In seeking broad-spectrum anticonvulsants to treat epilepsy and other neurological

273 Propranolol, the beta-blocker, and the anticonvulsant topiramate are effective for migraine pre

274 The anticonvulsant topiramate is effective for migraine prev

275 The anticonvulsant topiramate was recently shown to be effec

276 We show that the clinically available anticonvulsant topiramate, when administered post-insult

277 to treatment with tricyclic antidepressants, anticonvulsants (topiramate), coenzyme Q-10, and L-carni

278 tors of remote seizures and active epilepsy (anticonvulsant treatment for remote seizure within prior

279 into why spontaneous seizures remit without anticonvulsant treatment.

280 JAK2/PI3K signaling may be novel targets for anticonvulsant treatments.

281 has also been mandated to be applied to all anticonvulsant trials and other centrally acting agents

282 sy had a recent breakthrough seizure despite anticonvulsant usage.

283 ), depression (HR, 1.30; 95% CI, 1.05-1.61), anticonvulsant use (HR, 1.35; 95% CI, 1.04-1.75), and la

284 energy injury (OR, 1.38; 95% CI, 1.27-1.49), anticonvulsant use (OR, 1.37; 95% CI, 1.31-1.43), osteop

285 Steroid treatment and anticonvulsant use were related to poorer CCRI performan

286 oid arthritis (OR, 1.58; 95% CI, 1.38-1.82), anticonvulsant use with benzodiazepines (OR, 1.49; 95% C

287 epression, abnormal renal or liver function, anticonvulsant use, labile international normalized rati

288 , attempted suicides, and violent deaths for anticonvulsants used in at least 100 treatment episodes

289 thoxyacetic acid and the commonly prescribed anticonvulsant valproic acid, both short-chain fatty aci

290 illness, use of antidepressants, and use of anticonvulsants versus lithium.

291 reased rate of end-stage CKD, whereas use of anticonvulsants was (1-2 prescriptions, HR = 0 [95% CI,

292 ,5-diones as potential broad-spectrum hybrid anticonvulsants was described.

293 nonketotic hyperglycinemia required multiple anticonvulsants, whereas patients with developmental quo

294 ribute an important component to binding for anticonvulsants, which compensates energetically for the

295 ical conditions, such as antidepressants and anticonvulsants, which were found empirically to be effe

296 tassium channels, we have docked these three anticonvulsants with residues identified by mutagenesis

297 onepileptic patients, suggesting that sudden anticonvulsant withdrawal alone, unaccompanied by seizur

298 velop in some epileptic patients after rapid anticonvulsant withdrawal.

299 This case is the first to associate anticonvulsant-withdrawal splenial abnormalities with ne

300 mnolence and dizziness with TCAs, SNRIs, and anticonvulsants; xerostomia with TCAs; and peripheral ed