ライフサイエンスコーパス: antifreeze

1 yields and require large volumes of solvent "antifreezes".

2 One of the best-known uses of methanol is as antifreeze.

3 or these phenomena and observed that peptoid antifreeze activities depend both on oligomer backbone s

4 tion, the mechanisms of their noncolligative antifreeze activity are probably quite similar.

5 expressing tobacco lines exhibited enhanced antifreeze activity as demonstrated by the ability to in

6 peptoid oligomers that possess "dual-action" antifreeze activity as exemplified by ice crystal growth

7 5), and a beetle AFP (DAFP1) with increasing antifreeze activity as potential additives for controlli

8 hemically synthesized sfAFP had the expected antifreeze activity in an ice recrystallization inhibiti

9 A in tobacco resulted in the accumulation of antifreeze activity in the apoplast of plants grown at g

10 We use terahertz spectroscopy to show that antifreeze activity is directly correlated with long-ran

11 We suggest that antifreeze activity may be induced because the AFGP pert

12 the presence of trehalose also enhances the antifreeze activity of AFPs.

13 ons make essential contributions to the high antifreeze activity of insect AFPs from the beetle Dendr

14 The absence of a distinct correlation in antifreeze activity points to a mechanistic difference i

15 ve independently evolved proteins exhibiting antifreeze activity that allows survival at subfreezing

16 The levels of thermal hysteresis (antifreeze activity) produced by purified antifreeze pro

17 Ser resulted in moderate to complete loss of antifreeze activity, depending on the number and positio

18 ulk water behavior strongly reduces the AFGP antifreeze activity, further supporting our model.

19 recipitation, and finally the enhancement of antifreeze activity.

20 o evaluate the role of threonine residues on antifreeze activity.

21 number of the hydrogen bonds the greater the antifreeze activity.

22 r the AF(G)Ps are well correlated with their antifreeze activity.

23 rupt the ice-like character and to eliminate antifreeze activity.

24 tive AFPs compared to the AFPs with moderate antifreeze activity.

25 For over three decades since the first fish antifreeze (AF) protein was discovered, many studies of

26 ily of synthetic oligomers with potential as antifreeze agents in food production and biomedicine.

27 t has also been assigned a role as water-ice antifreeze and methane hydrate inhibitor which is though

28 sms of winter flounder and shorthorn sculpin antifreeze binding to ice are compared.

29 and structural analyses indicated that this antifreeze contains a beta-mannopyranosyl-(1-->4) beta-x

30 tive of the presence of large-molecular-mass antifreezes (e.g., antifreeze proteins), has been descri

31 ave gained a large interest for their use in antifreeze formulations for water-based materials, such

32 These results demonstrate that synthetic antifreeze (glyco)protein mimics could have a crucial ro

33 Antifreeze (glyco)proteins are found in polar fish speci

34 early demonstrate that biomimetic analogs of antifreeze (glyco)proteins should be tailored to the spe

35 rowth of ice crystals in a manner similar to antifreeze (glyco)proteins to enhance the cryopreservati

36 lying the quintessential adaptive phenotype, antifreeze glycoprotein (AFGP) that enables Antarctic no

37 m induces ticks to express Ixodes scapularis antifreeze glycoprotein (iafgp), which encodes a protein

38 the solution structure of the 14-amino acid antifreeze glycoprotein AFGP-8 have concluded that the m

39 The (1)H- and (13)C-NMR spectra of antifreeze glycoprotein fractions 1-5 from Antarctic cod

40 We identified an I. scapularis antifreeze glycoprotein, designated IAFGP, and demonstra

41 injury owing to induced expression of tick "antifreeze glycoprotein." This allows A. phagocytophilum

42 Antifreeze proteins (AFPs) and antifreeze glycoproteins (AFGPs) enable the survival of

43 The origin of antifreeze glycoproteins (AFGPs) in Antarctic notothenio

44 We have found that the antifreeze glycoproteins (AFGPs) of the predominant Anta

45 s have evolved antifreeze proteins (AFPs) or antifreeze glycoproteins (AFGPs) to avoid inoculative fr

46 and superorders), yet produce near-identical antifreeze glycoproteins (AFGPs) to survive in their res

47 Antifreeze glycoproteins (AFGPs), found in the blood of

48 Antifreeze glycoproteins from the Greenland cod Boreogad

49 It appears that antifreeze proteins and antifreeze glycoproteins have reached different evolutio

50 d in the activity of antifreeze proteins and antifreeze glycoproteins.

51 Methanol is also assigned a major role as antifreeze in giving icy planetary bodies (e.g., Titan)

52 This xylomannan is the first TH-producing antifreeze isolated from a freeze-tolerant animal and th

53 as this will accelerate the discovery of new antifreeze mimics.

54 y roles in the ice-binding properties of the antifreeze peptide.

55 o mechanisms for activity of winter flounder antifreeze peptide.

56 ion for the prevalence of such structures in antifreeze peptides produced by cold-weather species, su

57 ogs of an alanine-rich, alpha-helical type I antifreeze polypeptide from the winter flounder were syn

58 ched different evolutionary solutions to the antifreeze problem, utilizing either a few precisely pos

59 As expected, D-sfAFP displays the same antifreeze properties as L-sfAFP, because ice presents a

60 ic elucidation of the molecular basis of the antifreeze properties of this unique protein.

61 he low-throughout assays associated with the antifreeze properties.

62 lvent interaction of an ice-binding type III antifreeze protein (AFP III) and ubiquitin a non-ice-bin

63 We have studied the winter flounder antifreeze protein (AFP) and two of its mutants using mo

64 The TH activity of an antifreeze protein (AFP) depends on the specific AFP and

65 stereospecific binding of shorthorn sculpin antifreeze protein (AFP) to (2 -1 0) secondary prism fac

66 An antifreeze protein (AFP) with no known homologs has been

67 rimary sequence of the mature spruce budworm antifreeze protein (sbwAFP) was constructed by primer ov

68 e recently discovered glycine-rich snow flea antifreeze protein (sfAFP) has no sequence homology with

69 Here, we show that, for the snow flea antifreeze protein (sfAFP), stability and cooperativity

70 termine the X-ray structure of the snow flea antifreeze protein (sfAFP).

71 Thus, the antifreeze protein can bind to the molecularly rough ice

72 We hypothesize that antifreeze protein diversity is an important contributor

73 dentification of a phenotype associated with antifreeze protein expression in plant tissue.

74 ed to investigate the mechanism by which the antifreeze protein from the spruce budworm, Choristoneur

75 A synthetic antifreeze protein gene was expressed in plants and redu

76 The antifreeze protein genes, both with and without the sign

77 ng that increased activity of the two-domain antifreeze protein is not dependent on structure of the

78 The sequence of carrot antifreeze protein is similar to that of polygalacturona

79 This opens up a new field of metallo-organic antifreeze protein mimetics and provides insight into th

80 initiate the crystallization process of the antifreeze protein solution.

81 s C, in part by synthesizing the most potent antifreeze protein studied thus far (RiAFP).

82 n the initial recognition and binding of the antifreeze protein to ice by lowering the barrier for bi

83 the properties of water at the surface of an antifreeze protein with femtosecond surface sum frequenc

84 fibrils formed from engineered R. inquisitor antifreeze protein, depending upon geometry, we estimate

85 ure of RD3, a naturally occurring two-domain antifreeze protein, suggests that the two nearly identic

86 yoprotection by a dehydrin is not due to any antifreeze protein-like activity, as has been reported p

87 or the repetitive tripeptide backbone of the antifreeze protein.

88 The gene for a thermal hysteresis (antifreeze) protein (sthp-64) from the bittersweet night

89 enes encoding insect, Dendroides canadensis, antifreeze proteins (AFP) were produced by Agrobacterium

90 Since antifreeze proteins (AFPs) act as KHIs, we have used the

91 Antifreeze proteins (AFPs) and antifreeze glycoproteins

92 Antifreeze proteins (AFPs) are a subset of ice-binding p

93 Antifreeze proteins (AFPs) are a unique class of protein

94 The primary sequences of type I antifreeze proteins (AFPs) are Ala rich and contain thre

95 Antifreeze proteins (AFPs) are found in fish, insects, p

96 Antifreeze proteins (AFPs) are of great importance for a

97 Type III antifreeze proteins (AFPs) are present in the body fluid

98 Antifreeze proteins (AFPs) are specific proteins that ar

99 The antifreeze proteins (AFPs) bind ice nuclei and depress t

100 Antifreeze proteins (AFPs) can produce a difference betw

101 Antifreeze proteins (AFPs) have been identified in certa

102 Antifreeze proteins (AFPs) have independently evolved in

103 Antifreeze proteins (AFPs) help some organisms resist fr

104 Antifreeze proteins (AFPs) make up a class of structural

105 Antifreeze proteins (AFPs) of polar marine teleost fishe

106 subpolar marine teleost fishes have evolved antifreeze proteins (AFPs) or antifreeze glycoproteins (

107 Antifreeze proteins (AFPs) protect certain cold-adapted

108 Antifreeze proteins (AFPs) protect certain organisms fro

109 Antifreeze proteins (AFPs) protect many plants and organ

110 It has been argued that for antifreeze proteins (AFPs) to stop ice crystal growth, t

111 Antifreeze proteins (AFPs), known to protect organisms f

112 basis of the cytoprotective capabilities of antifreeze proteins (AFPs), we hypothesized that supplem

113 om freezing by the presence of extracellular antifreeze proteins (AFPs), which bind to ice, modify it

114 limit supercooling and induce freezing, and antifreeze proteins (AFPs), which function to prevent fr

115 dy plants, and overwintering insects produce antifreeze proteins (AFPs), which lower the freezing poi

116 s (antifreeze activity) produced by purified antifreeze proteins (DAFPs) from the larvae of the beetl

117 Dendroides canadensis produce a family of 13 antifreeze proteins (DAFPs), four of which are in the he

118 It appears that antifreeze proteins and antifreeze glycoproteins have re

119 both have been implicated in the activity of antifreeze proteins and antifreeze glycoproteins.

120 f hydrogen bond dynamics for the function of antifreeze proteins and for molecular recognition.

121 Antifreeze proteins and glycoproteins [AF(G)Ps] have bee

122 que polysaccharide resemble those present in antifreeze proteins and glycoproteins.

123 Type III antifreeze proteins are found in Arctic and Antarctic ee

124 vation of donor cells and tissue, but native antifreeze proteins are often not suitable, nor easily a

125 Antifreeze proteins are produced by extremophile species

126 ers which have no structural similarities to antifreeze proteins but reproduce the same macroscopic p

127 ave used site-selective strategies to attach antifreeze proteins found in Arctic fish and insects to

128 Antifreeze proteins from polar fish species are remarkab

129 olecular evolution and diversity of Type III antifreeze proteins in a single individual Antarctic fis

130 ng avoidance conferred by different types of antifreeze proteins in various polar and subpolar fishes

131 Although structurally diverse, all antifreeze proteins interact with ice surfaces, depress

132 Antifreeze proteins lower the noncolligative freezing po

133 carrot shares these functional features with antifreeze proteins of fish.

134 Antifreeze proteins prevent ice crystal growth in extrac

135 pted to live at subzero temperatures express antifreeze proteins that improve their tolerance to free

136 proline as a minimum (bio)synthetic mimic of antifreeze proteins that is accessible by solution, soli

137 tures (spruce budworm and Rhagium inquisitor antifreeze proteins) derived from sonication-based measu

138 e of large-molecular-mass antifreezes (e.g., antifreeze proteins), has been described in animals, pla

139 For instance, antifreeze proteins, bovine serum albumin, and ovomucoid

140 Ice-binding proteins (IBPs), also known as antifreeze proteins, were added to ice cream to investig

141 ilar to that of freezing point depression by antifreeze proteins.

142 synthetic macromolecular (polymer) mimics of antifreeze proteins.

143 Such repeats are a common feature of animal antifreeze proteins.

144 ch is known as an enhancer of certain insect antifreeze proteins.

145 mal hysteresis as a functional effect of the antifreeze proteins.

146 comparable to that of the most active insect antifreeze proteins.

147 ore, we identify three properties of Type I "antifreeze" proteins that discriminate among these two o

148 al structure of the fish antifreeze type III antifreeze structure, these codons correspond to amino a

149 Instead of commonly used colligative antifreezes such as salts and alcohols, the advantage of

150 the three-dimensional structure of the fish antifreeze type III antifreeze structure, these codons c