ライフサイエンスコーパス: antigene

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1 A target expands its potential utility as an antigene agent or hybridization probe.

2 The novel TFO can be developed into a potent antigene agent, and its design strategy applied to simil

3 Here we describe a protocol for designing antigene agents and introducing them into cells.

4 ecognition properties which may be useful as antigene agents or tools in molecular biology.

5 ave been extensively studied as antisense or antigene agents that can potentially modulate the expres

6 f the progesterone receptor (PR) function as antigene agents to block PR expression.

7 s are good candidates for further testing as antigene agents.

8 onucleotides have been used as antisense and antigene agents.

9 omings by serving as effective antisense and antigene agents.

10 attractive features as diagnostic probes and antigene agents.

11 of the present work was to characterize the antigene and antiproliferative activity of a triple heli

12 at the c-myc-targeted PS-TFO is an effective antigene and antiproliferative agent, with potential for

13 se of their successful use within antisense, antigene, and other gene-targeting strategies.

14 tions should be considered for antisense and antigene applications.

15 These findings support the feasibility of an antigene approach for the therapeutic regulation of spec

16 Earlier, we developed an antigene approach, using a type alpha1(I) collagen gene

17 cations to phototriggered antisense-based or antigene-based genetic tools, diagnostic agents and drug

18 the biological activity of TFOs as potential antigene compounds has been limited by cellular uptake.

19 ed (e.g., when PNAs are used as antisense or antigene drugs).

20 antigene peptide nucleic acids (agPNAs) and antigene duplex RNAs (agRNAs) block gene expression and

21 To test this hypothesis, we synthesized antigene LNAs (agLNAs) complementary to sequences within

22 Here, we show that antigene locked nucleic acids (agLNAs) reduce RNA levels

23 chromosomal DNA and that LNAs are bona fide antigene molecules.

24 xo- containing oligomers may find utility as antigene oligonucleotide reagents.

25 We have shown that antigene peptide nucleic acids (agPNAs) and antigene dup

26 plex DNA by strand invasion, suggesting that antigene PNAs (agPNAs) can be important tools for explor

27 y may complicate attempts to identify potent antigene PNAs.

28 Neu, mutants of c-Neu, polyomavirus middle T antigene (PyV-mT), Ras, and bi-transgenic for ErbB2/Neu

29 Antigene RNAs (agRNAs) are small RNA duplexes that targe

30 ulating gene expression by promoter-targeted antigene RNAs (agRNAs) will require identification of th

31 Equally important was that an antigene strategy, the sense PNA, was shown in vivo to b

32 chniques such as in situ hybridization, PCR, antigene targeting, and microarrays.

33 zing ligands, with potential applications in antigene therapeutics.

34 otides in biological solutions, antisense or antigene therapies aimed at modulation of specific gene

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