ライフサイエンスコーパス: antimicrobial agent

1 st active compound was lomofungin, a natural antimicrobial agent.

2 s (AgNPs) into base materials to serve as an antimicrobial agent.

3 te blood cell count, and be started on a new antimicrobial agent.

4 idone-iodine (PVI) is principally used as an antimicrobial agent.

5 ntified reuterin to be the precursor-induced antimicrobial agent.

6 o the activity and concentration for a given antimicrobial agent.

7 novel immunomodulating agent rather than an antimicrobial agent.

8 it a remarkably efficient optically mediated antimicrobial agent.

9 nion to generate hypochlorous acid, a potent antimicrobial agent.

10 e was the most frequently prescribed (24.6%) antimicrobial agent.

11 safe and effective use of ZnPT as a topical antimicrobial agent.

12 gdunensis are susceptible to narrow-spectrum antimicrobial agents.

13 pecies: sanitation, nutrition, vaccines, and antimicrobial agents.

14 of these 4-oxazolidinone natural products as antimicrobial agents.

15 fer potential insight into targets for novel antimicrobial agents.

16 analogues identified by previous studies as antimicrobial agents.

17 contribute in identifying novel targets for antimicrobial agents.

18 a concomitant increase in the need for novel antimicrobial agents.

19 cline, doxycycline, and other broad-spectrum antimicrobial agents.

20 s designed to improve the appropriate use of antimicrobial agents.

21 rves as a barrier against the penetration of antimicrobial agents.

22 uple regimens in areas of high resistance to antimicrobial agents.

23 ould be an effective strategy to develop new antimicrobial agents.

24 biofilms is their extraordinary tolerance to antimicrobial agents.

25 directions for the design of next-generation antimicrobial agents.

26 rial cell envelope can enhance resistance to antimicrobial agents.

27 uginosa biofilms and to resist the action of antimicrobial agents.

28 ynthesis of highly specific enantioselective antimicrobial agents.

29 omycin, clindamycin, tetracycline, and other antimicrobial agents.

30 nts were initially treated with intravitreal antimicrobial agents.

31 included evidence of treatment with specific antimicrobial agents.

32 prevention practices and appropriate use of antimicrobial agents.

33 and recalcitrance to killing by microbicidal antimicrobial agents.

34 I, is an attractive target for the design of antimicrobial agents.

35 regulatory mechanism to resist the action of antimicrobial agents.

36 esigned with the aim to obtain potential new antimicrobial agents.

37 the design of lipidated gamma-AApeptides as antimicrobial agents.

38 for the development of potent broad-spectrum antimicrobial agents.

39 rance of biofilms to killing by microbicidal antimicrobial agents.

40 ntal treatment, and 1 month after the use of antimicrobial agents.

41 k of biofilms is their profound tolerance of antimicrobial agents.

42 he development of novel and highly selective antimicrobial agents.

43 biofilms, which render it more resistant to antimicrobial agents.

44 inhibitor development that could lead to new antimicrobial agents.

45 prototypes for the design of unconventional antimicrobial agents.

46 ditionally using different types of standard antimicrobial agents.

47 t also confers protective advantages against antimicrobial agents.

48 etry protein profiles, and susceptibility to antimicrobial agents.

49 us in protection of the bacterial cells from antimicrobial agents.

50 anisms that exhibited resistance to multiple antimicrobial agents.

51 to human teeth and notoriously resistant to antimicrobial agents.

52 ight into the development and application of antimicrobial agents.

53 , suggesting that they may be susceptible to antimicrobial agents.

54 ay are potential targets in the discovery of antimicrobial agents.

55 iology but also for the development of novel antimicrobial agents.

56 s a target for development of anticancer and antimicrobial agents.

57 early there is a growing need for additional antimicrobial agents.

58 n genes, and tested for susceptibility to 14 antimicrobial agents.

59 ated with their ability to release long-term antimicrobial agents.

60 of the infectious agents and the response to antimicrobial agents.

61 ux is the best construct for testing various antimicrobial agents.

62 een on the rise due to the widespread use of antimicrobial agents.

63 hnology for multiple applications, including antimicrobial agents.

64 lity testing for less commonly used or newer antimicrobial agents.

65 e represent an avenue for development of new antimicrobial agents.

66 tegy that would allow recycling of substrate antimicrobial agents.

67 ng future design of more potent and specific antimicrobial agents.

68 ocidal activity of an underutilized class of antimicrobial agents.

69 ms demonstrate a decreased susceptibility to antimicrobial agents.

70 ntives for pharmaceutical development of new antimicrobial agents.

71 important for survival following exposure to antimicrobial agents.

72 t and disrupt bacterial membranes, acting as antimicrobial agents.

73 these drugs could lead to novel, broad range antimicrobial agents.

74 can be exploited to design disease-specific antimicrobial agents.

75 ments and contributing to resistance against antimicrobial agents.

76 promising target for the development of new antimicrobial agents.

77 erapeutic CO delivery in animals, are potent antimicrobial agents.

78 and P. aeruginosa were susceptible to fewer antimicrobial agents.

79 nisms to avoid being killed by commonly used antimicrobial agents.

80 tested that showed resistance to a class of antimicrobial agents.

81 bials) or an alternative topical or systemic antimicrobial agent?

82 elopment do biofilms gain their tolerance to antimicrobial agents?

83 49.7%-52.3%) patients were on 3611 systemic antimicrobial agents; 462 (12.8%) were prescribed for su

84 tency </=7 days were caused predominantly by antimicrobial agents (71%).

85 rance of biofilms to killing by bactericidal antimicrobial agents, a phenotype comparable to that obs

86 noparticles to carry and selectively release antimicrobial agents after attachment or within oral bio

87 he RBC-nanogel system as a new and effective antimicrobial agent against MRSA infection.

88 Pentamidine is an effective antimicrobial agent against several human pathogens, but

89 itative method to assess combined killing of antimicrobial agents against 2 multidrug-resistant bacte

90 ties of gallium maltolate (GaM) and 20 other antimicrobial agents against clinical equine isolates of

91 gest a potential role for AHAS inhibitors as antimicrobial agents against pulmonary pathogens.

92 ated the activity of ceftaroline and various antimicrobial agents against S. aureus isolates accordin

93 structural basis for the development of new antimicrobial agents against this family of bacterial 2-

94 d to monitor susceptibility to commonly used antimicrobial agents among important pathogens.

95 Ortho-phenylphenol (OPP) is an antimicrobial agent and an active ingredient of EPA-regi

96 the innate immune system may use zinc as an antimicrobial agent and that zinc efflux is an important

97 Despite the use of appropriate antimicrobial agents and advanced supportive care, the m

98 insecticides; documentation of links between antimicrobial agents and alterations in hormone response

99 hat soluble factors including AMPs are hCVAM antimicrobial agents and are consistent with a role for

100 acyclines are used in periodontal therapy as antimicrobial agents and as inhibitors of matrix metallo

101 ride (LPS), thereby increasing resistance to antimicrobial agents and avoidance of the host immune sy

102 ance because they decrease susceptibility to antimicrobial agents and enhance the spread of antimicro

103 render various organisms less susceptible to antimicrobial agents and environmental stresses.

104 This efficient method allows antimicrobial agents and exposure conditions to be teste

105 ty to resist the killing effects of multiple antimicrobial agents and human serum.

106 per describes the development and use of new antimicrobial agents and immune-based and host-directed

107 ly, recognizes and extrudes a broad range of antimicrobial agents and is essential for Campylobacter

108 design principles toward the development of antimicrobial agents and materials.

109 sent attractive targets for developing novel antimicrobial agents and modulators of immune responses

110 terococcal cell membrane response to diverse antimicrobial agents and peptides; as such, LiaR represe

111 Modified use of antimicrobial agents and public health interventions, co

112 e species and have promising applications as antimicrobial agents and scaffolds for peptide drugs.

113 gram-negative bacteria to resist killing by antimicrobial agents and to avoid detection by host immu

114 ying key targets for development of improved antimicrobial agents and vaccines.

115 rade water preserved with sodium omadine, an antimicrobial agent, and sodium thiosulfate, a dechlorin

116 for congenital blistering diseases and as an antimicrobial agent, and we discuss limitations and futu

117 medicinal herbs, which are known to contain antimicrobial agents, and are rich in different active s

118 utamicum cultured in the presence of certain antimicrobial agents, and elucidation of this system exp

119 is highly sensitive to oxidants and several antimicrobial agents, and exhibits diminished intramacro

120 treatment (intensive care, a combination of antimicrobial agents, and nutritional support, with or w

121 tained low-efficiency dialysis, antibiotics, antimicrobial agents, and pharmacokinetics.

122 hospital resources, absence of available new antimicrobial agents, and potential lack of reimbursemen

123 nizes and actively extrudes a broad range of antimicrobial agents, and promotes the intrinsic resista

124 a promising new area for the development of antimicrobial agents, and that many of the best PDF inhi

125 sts can aid the development of sorely needed antimicrobial agents, and the study of antimicrobial age

126 (PFGE); SCCmec typing; susceptibility to 15 antimicrobial agents; and PCR analysis of staphylococcal

127 nabsorbed macrocyclic compound, is the first antimicrobial agent approved by the FDA for the treatmen

128 Because antimicrobial agents are generally contraindicated in pa

129 New antimicrobial agents are greatly needed to treat infecti

130 MICs to most antimicrobial agents are relatively low.

131 Moreover, this class of antimicrobial agents are resistant to proteolytic degrad

132 thway is a target for the development of new antimicrobial agents as it is essential for microorganis

133 d DeltasagS biofilm cells as recalcitrant to antimicrobial agents as wild-type biofilms, likely by re

134 rane is therefore critical to developing new antimicrobial agents, as this membrane makes direct cont

135 Is treatment with topical or systemic antimicrobial agents associated with better venous leg u

136 e-NO hybrids represent the first dual-action antimicrobial agent based on the baterial QS inhibition

137 We have developed a class of selective antimicrobial agents based on the recognition of the sha

138 ontribute to the development of vaccines and antimicrobial agents, but they have focused chiefly on v

139 while eDNA can serve as a nutrient and as an antimicrobial agent by chelating essential cations.

140 complex structure enhances the resistance to antimicrobial agents by limiting the transport of active

141 The emergence of resistance to multiple antimicrobial agents by pathogenic bacteria has become a

142 eeded antimicrobial agents, and the study of antimicrobial agents can help immunologists discover tar

143 ll patients with the broad-spectrum, topical antimicrobial agent chlorhexidine is widely performed an

144 e discusses indications for intraventricular antimicrobial agents, choice of antibiotics, strategies

145 For all of the organism-antimicrobial agent combinations tested, categorical agr

146 d rapid AST results for most of the organism-antimicrobial agent combinations tested.

147 Green tea extract is a naturally occurring antimicrobial agent, consisting of polyphenols (catechin

148 ections are readily curable with appropriate antimicrobial agents; cryptosporidiosis and C. difficile

149 No study comparing 2 antimicrobial agents demonstrated a statistically signif

150 Pharmacokinetics/pharmacodynamics of antimicrobial agents, differences among bacterial specie

151 d lack of R&D productivity of new classes of antimicrobial agents directed against Gram-negative bact

152 r of days an infant was exposed to 1 or more antimicrobial agents divided by the total length of hosp

153 aminated procedures, additional prophylactic antimicrobial agent doses should not be administered aft

154 icrobial strains and their interactions with antimicrobial agents, e.g., the Kirby-Bauer susceptibili

155 to increased resistance of this bacterium to antimicrobial agents, especially Clarithromycin.

156 st MSSA isolates remained susceptible to all antimicrobial agents except erythromycin (79.1 and 76.0%

157 The antimicrobial agent flucloxacillin is a common cause of

158 al of WR12 and D-IK8 to be used as a topical antimicrobial agent for the treatment of staphylococcal

159 s, micro-organisms to identify fungitoxic or antimicrobial agents for controlling serious plant patho

160 une stimuli currently under investigation as antimicrobial agents for different species.

161 dulation of proliferative vitreoretinopathy, antimicrobial agents for endophthalmitis, antiangiogenic

162 oxidants and also in food industry as strong antimicrobial agents for food preservation.

163 We investigated several antimicrobial agents for potential synergy with polymyxi

164 apid selection and distribution of effective antimicrobial agents for treatment and postexposure prop

165 Triclosan (TCS) and triclocarban (TCC) are antimicrobial agents formulated in a wide variety of con

166 l, and bis(5-chloro-2-hydroxyphenyl)methane) antimicrobial agents found in biosolids were analyzed.

167 flux pumps, which expel proteins, toxins and antimicrobial agents from Gram-negative bacteria.

168 Escherichia coli extruding a vast variety of antimicrobial agents from the cell.

169 s, to data on infectious diseases and use of antimicrobial agents from the National Patient Register

170 used to tailor the delivery of combinatorial antimicrobial agents from various metallic implantable d

171 anoparticles (AgNPs) in consumer products as antimicrobial agents has prompted extensive research tow

172 Progressive resistance to antimicrobial agents has reduced options for gonorrhea t

173 The widespread emergence of resistance to antimicrobial agents has taken mammoth dimension and war

174 ated with drug-resistant pathogens, and many antimicrobial agents have adverse effects restricting th

175 ent of novel but still conventional systemic antimicrobial agents, having only a single mode or site

176 e attractive targets for developing nontoxic antimicrobial agents, herbicides, and antiparasite drugs

177 re potential targets for developing nontoxic antimicrobial agents, herbicides, and antiparasite drugs

178 PBGS modulators for potential application as antimicrobial agents, herbicides, or drugs for porphyric

179 Based on this analysis, copper use as an antimicrobial agent in algae resistant shingles and trea

180 Copper is used as an antimicrobial agent in building materials such as algae-

181 ers via wastewater effluents, triclosan, the antimicrobial agent in handsoaps, and chlorinated triclo

182 r 5-aminolevulinic acid, which is used as an antimicrobial agent in photodynamic therapy, potentiates

183 regulatory mechanism to resist the action of antimicrobial agents in a BrlR-dependent manner which af

184 ractive targets for the development of novel antimicrobial agents in a time of rising antibiotic resi

185 In contrast, the effect of antimicrobial agents in adopted immunity, although funda

186 number of studies suggest that both of these antimicrobial agents in combination are more effective i

187 bination treatment with SWCNTs and oxidizing antimicrobial agents in developing highly effective spor

188 NO2(-) and Cl(-) as they serve as important antimicrobial agents in meat to inhibit the growth of ba

189 shown to help reduce the use of unnecessary antimicrobial agents in the hospital setting.

190 with the downturn in the development of new antimicrobial agents in the pharmaceutical industry pose

191 e role of intraventricular administration of antimicrobial agents in the treatment of patients with b

192 of efflux confer inherent resistance to many antimicrobial agents, including fluoroquinolones, due to

193 The patient received courses of several antimicrobial agents, including linezolid for 79 days.

194 es in bacterial susceptibility to a panel of antimicrobial agents, including tigecycline.

195 aces creating biofilms that are resistant to antimicrobial agents, increasing mortality and morbidity

196 B. subtilis to other cell envelope-targeted antimicrobial agents, indicating that the mutation speci

197 antimicrobial film and the diffusion of the antimicrobial agent into the food.

198 aluated the benefits of local application of antimicrobial agents into ERC contrast media in preventi

199 chanisms could be harnessed to deliver other antimicrobial agents into Gram-negative bacteria.

200 n and animal pathogen to the introduction of antimicrobial agents into the clinical environment.

201 Antifolates, which are among the first antimicrobial agents invented, inhibit cell growth by cr

202 of new antibiotics or localised delivery of antimicrobial agents, iron sequestration, inhibition of

203 No antimicrobial agent is clearly superior for the initial

204 Before a new antimicrobial agent is used to treat infections, it must

205 The decreasing effectiveness of antimicrobial agents is a growing global public health c

206 Bacterial resistance to antimicrobial agents is a growing problem worldwide.

207 ve synthetic route to the complex anticancer antimicrobial agent kinamycin F (3).

208 Pseudomonas aeruginosa biofilm tolerance to antimicrobial agents known as multidrug efflux pump subs

209 ield after 24 h, a valuable precursor of the antimicrobial agent Levofloxacin.

210 1,4]oxazine, which is a key precursor of the antimicrobial agent Levofloxacin.

211 its that have been successfully developed as antimicrobial agents, lung surfactant replacements, enzy

212 pe tested, led to enhanced resistance to the antimicrobial agent lysozyme.

213 Some antimicrobial agents may attenuate MMP activity.

214 imely management with the appropriate use of antimicrobial agents may optimize visual outcomes.

215 In contrast to growth-based antimicrobial agents, membrane-targeting drugs effective

216 mal inhibitory concentrations (MICs) of four antimicrobial agents, namely, cefazolin, ceftazidime, ce

217 Lincomycin A is a potent antimicrobial agent noted for its unusual C1 methylmerca

218 bute to the special ecology and tolerance to antimicrobial agents of biofilms.

219 ing by BrlR, and recalcitrance to killing by antimicrobial agents of DeltasagS biofilm cells.

220 Because antimicrobial agents of different classes and varying ac

221 mechanism of resistance to host defenses and antimicrobial agents of diverse classes.

222 useful peptide template for developing novel antimicrobial agents of therapeutic use.

223 r species bacteremia and received at least 1 antimicrobial agent, of whom 52 (14%) died during hospit

224 l cellulitis, and to look for the effects of antimicrobial agents on these biofilms by colorimetric a

225 ntibiotherapy; escalation (addition of a new antimicrobial agent or change in antibiotic to one with

226 ur groups: de-escalation (interruption of an antimicrobial agent or change of antibiotic to one with

227 be managed conservatively with prophylactic antimicrobial agents or curatively with hematopoietic st

228 cially available FDA-cleared tests for newer antimicrobial agents or for older agents with updated br

229 fied as fully susceptible, resistant to >/=1 antimicrobial agent, or resistant to a first-line agent.

230 resistance that results in the extrusion of antimicrobial agents outside the bacterial cell.

231 he risk associated with inappropriate use of antimicrobial agents, patients with suspected sepsis mus

232 susceptibility testing for 12 commonly used antimicrobial agents (penicillin, methicillin, erythromy

233 4 weeks of treatment with two or more active antimicrobial agents, plus removal of the intravascular

234 ignificance of S. lugdunensis isolation, the antimicrobial agents prescribed, if any, and the clinica

235 Initial trials with six antimicrobial agents produced incorrect susceptibility c

236 h the demonstrated ability of polyketides as antimicrobial agents, provides strong motivation for und

237 For Phoenix, the EAs of individual antimicrobial agents ranged from 90.4% (clindamycin) to

238 Helicobacter pylori have become resistant to antimicrobial agents, reducing eradication rates.

239 Active packaging foils with incorporated antimicrobial agents release the active ingredient durin

240 The development of antimicrobial agents represents one of the most signific

241 Pseudomonas aeruginosa, biofilm tolerance to antimicrobial agents requires the biofilm-specific MerR-

242 A large number of available antimicrobial agents retain very good in vitro activity

243 apy with certain antiepileptic drugs and the antimicrobial agent rifampin, resulting in drug-induced

244 rsenicals such as the trivalent forms of the antimicrobial agents roxarsone (Rox(III)), nitarsone (Ni

245 Antimicrobial agents secreted into urine potentially pla

246 Treatment of shigellosis with appropriate antimicrobial agents shortens duration of illness and ba

247 Topical antimicrobial agents should not be applied to the surgic

248 Macromolecular antimicrobial agents such as cationic polymers and pepti

249 athogens has led to a search for alternative antimicrobial agents such as linezolid.

250 een intensified due to their high content of antimicrobial agents such as polyphenols, i.e. flavonoid

251 mended to detect resistance to commonly used antimicrobial agents; such testing is complicated by dif

252 rate novel binding specificities and dynamic antimicrobial agents suggests numerous applications.

253 used on the discovery and development of new antimicrobial agents targeted against this important opp

254 offer insight into the development of novel antimicrobial agents targeting the dimeric antibiotic ta

255 aminoglycosides appear to be less effective antimicrobial agents than other antibiotics, synthetic a

256 mitis group organisms are resistant to more antimicrobial agents than the other VGS species.

257 Triclosan is a widespread antimicrobial agent that accumulates in anaerobic digest

258 Transferrin is a promising, novel antimicrobial agent that merits clinical investigation.

259 GML is a potent antimicrobial agent that targets a range of bacteria, fu

260 des (ADEPs) represent an attractive class of antimicrobial agents that act through dysregulation of c

261 These host cells contain and produce many antimicrobial agents that are effective at killing bacte

262 anism by which bacteria evade the effects of antimicrobial agents that are substrates.

263 cs are post-translationally modified peptide antimicrobial agents that are synthesized with an N-term

264 ntarium of pattern recognition molecules and antimicrobial agents that identify and eliminate pathoge

265 Antimicrobial agents that inhibit protein synthesis such

266 iofilms is their extraordinary resistance to antimicrobial agents that is activated during early biof

267 is a viable strategy for the development of antimicrobial agents that target bacterial pathogens.

268 A major limitation in developing antimicrobial agents that target DapE has been the lack

269 ith the purpose of developing broad spectrum antimicrobial agents that target the substrate and nucle

270 4-AP might be useful where silver is used as antimicrobial agent to speed its uptake.

271 ikely than control subjects to have taken an antimicrobial agent to which Newport-MDRAmpC is resistan

272 rove valuable for the design of new types of antimicrobial agents to combat the emergence of antibiot

273 ng epidemics and identification of potential antimicrobial agents to expedite clinical decision-makin

274 een growing interest in the discovery of new antimicrobial agents to increase safety and shelf-life o

275 emporary testing issues, and (iii) choice of antimicrobial agents to test for Streptococcus pneumonia

276 and the feasibility of using NPs to deliver antimicrobial agents to treat a cutaneous pathogen.

277 Clinicians have been resorting to older antimicrobial agents to treat infections caused by MDR A

278 Ortho-phenylphenol (OPP) is an antimicrobial agent used as an active ingredient in seve

279 otentiates the activity of metronidazole, an antimicrobial agent used in the treatment of bacterial v

280 e published MIC interpretive criteria for 13 antimicrobial agents used for either therapy or prophyla

281 s and found Etest to be reliable for testing antimicrobial agents used to treat Y. pestis, except for

282 the principle of multivalency to create new antimicrobial agents using the reactive polymaleic anhyd

283 cin disaccharide to provide even more potent antimicrobial agents [VRE minimum inhibitory concentrati

284 Biofilm formation and resistance to antimicrobial agents was also observed in several clades

285 The efficacy of rifaximin, a nonabsorbed antimicrobial agent, was demonstrated in the treatment o

286 Targeted antimicrobial agents were administered, and the patient

287 Antimicrobial agents were cited as most effective but we

288 robial susceptibility tests against thirteen antimicrobial agents were determined using the K-B diffu

289 In total, 25 antimicrobial agents were examined.

290 Six antimicrobial agents were tested against 39 Brucella iso

291 hydrolysates were found to act as potential antimicrobial agents when incubated with E. coli and Bac

292 Sulfonamides are antimicrobial agents widely employed in animal productio

293 Dalbavancin is a lipoglycopeptide antimicrobial agent with a potency significantly better

294 Fidaxomicin (FDX) is a novel antimicrobial agent with narrow-spectrum and potent bact

295 PCMC (4-chloro-m-cresol), household derived antimicrobial agent with no known exposure and human met

296 ein product was found suitable for use as an antimicrobial agent with potent antibacterial activity,

297 RE-active therapy and the development of new antimicrobial agents with activity against CRE.

298 ered an attractive target for developing new antimicrobial agents with novel mechanisms of action.

299 cells being significantly more resistant to antimicrobial agents, with increased resistance correlat

300 n part to this organism's resistance to many antimicrobial agents, with pneumonia and bacteremia as t