ライフサイエンスコーパス: antimicrobial resistance

1 e data are essential to reduce the burden of antimicrobial resistance.

2 uring outbreak investigation and tracking of antimicrobial resistance.

3 stigate gonorrhoea transmission and to track antimicrobial resistance.

4 emerging infection due to its high levels of antimicrobial resistance.

5 for management of gonococcal infections and antimicrobial resistance.

6 essary antibiotic prescribing contributes to antimicrobial resistance.

7 monolayer of the outer membrane and promote antimicrobial resistance.

8 for improved and accurate identification of antimicrobial resistance.

9 treatment, contributing to the emergence of antimicrobial resistance.

10 with worrisome changes in global patterns of antimicrobial resistance.

11 designed to investigate the effect of ADE on antimicrobial resistance.

12 linical laboratory is paramount to combating antimicrobial resistance.

13 he only factor significantly associated with antimicrobial resistance.

14 e of antimicrobials in a world of escalating antimicrobial resistance.

15 atment for gonorrhea has been complicated by antimicrobial resistance.

16 ract infections is challenging due to rising antimicrobial resistance.

17 timicrobial agents and enhance the spread of antimicrobial resistance.

18 e costs, and preventing further emergence of antimicrobial resistance.

19 but promotes expression of genes involved in antimicrobial resistance.

20 composite of recurrences and scarring), and antimicrobial resistance.

21 increasing propensity for the acquisition of antimicrobial resistance.

22 tics are urgently needed to address emerging antimicrobial resistance.

23 uture public health interventions to address antimicrobial resistance.

24 stigation of molecular mechanisms conferring antimicrobial resistance.

25 al responses with potential implications for antimicrobial resistance.

26 y, in the wider context of increasing global antimicrobial resistance.

27 or >70% (ciprofloxacin, gentamicin) of total antimicrobial resistance.

28 elations exist between income inequality and antimicrobial resistance.

29 at could causally link income inequality and antimicrobial resistance.

30 anding the ecology of bacterial zoonoses and antimicrobial resistance.

31 and to indicators of the economic burden of antimicrobial resistance.

32 zed set of immune cells as sole guardians of antimicrobial resistance.

33 increasingly important in the current age of antimicrobial resistance.

34 ffect on enterococcal envelope integrity and antimicrobial resistance.

35 and challenges posed by emerging gonococcal antimicrobial resistance.

36 e used to treat pneumonia despite increasing antimicrobial resistance.

37 hey could potentially serve as reservoirs of antimicrobial resistance.

38 reduce health-care-associated infection and antimicrobial resistance.

39 ere analyzed for toxin genes, genotypes, and antimicrobial resistance.

40 to use in the fight against the evolution of antimicrobial resistance.

41 survival in a setting with low prevalence of antimicrobial resistance.

42 re effective treatment and slow emergence of antimicrobial resistance.

43 in a global approach to reduce the burden of antimicrobial resistance.

44 discuss the role of monitoring in countering antimicrobial resistance.

45 a robust strategy for combating pneumococcal antimicrobial resistance.

46 tious diseases, develop vaccines, and combat antimicrobial resistance, all with increased accuracy, t

47 otbed for the emergence and proliferation of antimicrobial resistance among bacteria.

48 The growing problem of antimicrobial resistance among bacterial pathogens, incl

49 We systematically reviewed studies of antimicrobial resistance among children in sub-Saharan A

50 s a potential strategy to reduce the risk of antimicrobial resistance among children with acute otiti

51 We describe antimicrobial resistance among nontyphoidal Salmonella b

52 Increasing antimicrobial resistance among pathogens causing complic

53 relevance, particularly given high rates of antimicrobial resistance among these pathogens.

54 Antimicrobial resistance (AMR) by Neisseria gonorrhoeae

55 The ever-growing threat of antimicrobial resistance (AMR) demands immediate counter

56 x accurately estimates the abundances of the antimicrobial resistance (AMR) gene families and enables

57 ales, although how hospitals themselves fuel antimicrobial resistance (AMR) in the wider environment

58 Surveillance of antimicrobial resistance (AMR) is an important component

59 Antimicrobial resistance (AMR) is becoming a major globa

60 The rising incidence of antimicrobial resistance (AMR) makes it imperative to un

61 The emergence and spread of antimicrobial resistance (AMR) mechanisms in bacterial p

62 ion notification system relating to regional antimicrobial resistance (AMR) on regional AMR infection

63 hospitals (TCHs) are thought to have higher antimicrobial resistance (AMR) rates when compared to sm

64 at this practice leads to the development of antimicrobial resistance (AMR) that can potentially spre

65 However, antimicrobial resistance (AMR) threatens this progress a

66 Antimicrobial resistance (AMR) threats are typically rep

67 iquitous commensal bacteria harbour genes of antimicrobial resistance (AMR), often on conjugative pla

68 Antimicrobial resistance (AMR), the ability of a bacteri

69 Responding to escalating antimicrobial resistance (AMR), the US Department of Def

70 ity reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the

71 nterest in using DNA-based methods to detect antimicrobial resistance (AMR), with targeted polymerase

72 threat to human health and biosecurity from antimicrobial resistance, an understanding of its mechan

73 important therapeutic option with increasing antimicrobial resistance and a diminishing number of act

74 Antimicrobial resistance and bacterial virulence factors

75 s time period in order to identify trends in antimicrobial resistance and circulating types.

76 The impact of broad-spectrum antibiotics on antimicrobial resistance and disruption of the beneficia

77 Given current challenges in antimicrobial resistance and drug development, infectiou

78 ew approach for rapidly detecting phenotypic antimicrobial resistance and for documenting growth attr

79 isms by which PrtR-regulated genes determine antimicrobial resistance and genotoxic stress survival.

80 potential to shape Salmonella pathogenicity, antimicrobial resistance and host-pathogen interactions.

81 allenges, from its own funding shortfalls to antimicrobial resistance and immense health inequities.

82 In an effort to decrease antimicrobial resistance and inappropriate antibiotic us

83 The prevalence of antimicrobial resistance and incidence of adverse events

84 ay a translational approach to the threat of antimicrobial resistance and inhibit the identification

85 comial pathogen that displays broad-spectrum antimicrobial resistance and is recognized as causing ch

86 ontribute to uptake of genes associated with antimicrobial resistance and pathogenicity.

87 tegies to attain the common goal of reducing antimicrobial resistance and preserving antimicrobials f

88 Although the emergence of antimicrobial resistance and selection of highly antibio

89 hese data highlight the rapid development of antimicrobial resistance and spread of V. cholerae O1 El

90 phenomenon mirrors the worldwide increase in antimicrobial resistance and the emergence of other MDR

91 that surveys poultry production to test for antimicrobial resistance and the occurrence of extended-

92 ence in infectious diseases characterized by antimicrobial resistance and therapeutic failure.

93 species and clonal group identification and antimicrobial resistance and virulence profiling, includ

94 isolates harbor plasmids that co-select for antimicrobial resistance and virulence, along with genes

95 are known to carry plasmids associated with antimicrobial resistance and virulence.

96 for assessing public health risks regarding antimicrobial resistance, and demonstrates that environm

97 and interfere with cell envelope integrity, antimicrobial resistance, and GIT colonization.

98 test for trend to examine trends in rates of antimicrobial resistance, and negative binomial regressi

99 uce inappropriate antibiotic usage, decrease antimicrobial resistance, and optimize patient outcomes.

100 ence for NCTC1, investigated the isolate for antimicrobial resistance, and undertook comparative gene

101 netic typing, to establish whether trends of antimicrobial resistance are caused by spread of resista

102 predictions including virulence factors and antimicrobial resistance are now available for 6193 comp

103 Strategies for decreasing antimicrobial resistances are of particular importance.

104 only to be antimicrobial drugs that lead to antimicrobial resistance but also to be chemotherapeutic

105 (MRSA) during persistent infection leads to antimicrobial resistance but may also impact host-pathog

106 CpxR was not required for intrinsic antimicrobial resistance, but CpxR activation enhanced r

107 Isolates were tested for antimicrobial resistance by broth microdilution.

108 a crucial supplement to efforts dealing with antimicrobial resistance by developing new therapeutic a

109 Strategies to reduce antimicrobial resistance by removing antimicrobial selec

110 We hypothesized that antimicrobial resistance can be reversed by targeting ch

111 However, the emergence of antimicrobial resistance combined with the downturn in t

112 Strategies to manage antimicrobial resistance consist of new antibiotics or l

113 Income inequality and antimicrobial resistance correlations which were moderat

114 trategy in efforts to address the escalating antimicrobial resistance crisis.

115 Detection of antimicrobial resistance currently relies on a conventio

116 Recent antimicrobial resistance data are lacking from inpatient

117 Antimicrobial resistance data were obtained from the Eur

118 To validate antimicrobial resistance data, in the absence of regiona

119 ly assessed in conjunction with contemporary antimicrobial resistance data.

120 000, with a special emphasis on genomes with antimicrobial resistance data.

121 itations, we present MEGARes, a hand-curated antimicrobial resistance database and annotation structu

122 Currently, antimicrobial resistance databases are tailored to small

123 Mycobacterium tuberculosis and to determine antimicrobial resistance, decades old technologies remai

124 s aeruginosa, and Serratia marcescens) and 6 antimicrobial resistance determinants (blaCTX-M, blaKPC,

125 ospitals, and showed that they have acquired antimicrobial resistance determinants for different beta

126 user-friendly sequence typing tool based on antimicrobial resistance determinants in Neisseria gonor

127 y was to characterize strains and associated antimicrobial resistance determinants of C. difficile is

128 ndardization of nomenclature associated with antimicrobial resistance determinants through an interna

129 The lineage had acquired multiple antimicrobial resistance determinants, and prevailing su

130 tion structure and variation, as well as the antimicrobial resistance determinants, of a systematic c

131 by acquisition of cell surface proteins and antimicrobial resistance determinants.

132 carriage of plasmids encoding antiseptic and antimicrobial resistance determinants.

133 Antimicrobial resistance differed by race, ethnicity, ag

134 construct the timeline of the acquisition of antimicrobial resistance during a major ongoing outbreak

135 To help address the growing problem of antimicrobial resistance, efforts should be undertaken t

136 timulus perception, signal transduction, and antimicrobial resistance employed by Bce-like detoxifica

137 PCR/ESI-MS detected all antimicrobial resistance encoded by mecA or vanA/B and i

138 tudies given the magnitude of the problem of antimicrobial resistance, especially regarding community

139 l centers as part of the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) Program.

140 The 2010 Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) Surveillance

141 resistance surveillance (Assessing Worldwide Antimicrobial Resistance Evaluation [AWARE] Program) in

142 The Assessing Worldwide Antimicrobial Resistance Evaluation Surveillance Program

143 ses in European countries so do the rates of antimicrobial resistance for bacteria including E. faeca

144 ong-term trends in bloodstream infection and antimicrobial resistance from this surveillance.

145 quencing, and assemblies sufficient for full antimicrobial resistance gene annotation were obtained w

146 Understanding the differences in antimicrobial resistance gene carriage between different

147 it real-time benchtop genomic sequencing and antimicrobial resistance gene detection in clinical isol

148 n methods (2D and rapid 1D) with the goal of antimicrobial resistance gene detection.

149 Little is known about the distribution of antimicrobial resistance genes (ARGs) between the intrac

150 tock production, residual antimicrobials and antimicrobial resistance genes (ARGs) could enter the en

151 ram-negative, and 5 yeast species) and three antimicrobial resistance genes (mecA, vanA/B, and blaKPC

152 communities might have a role in transfer of antimicrobial resistance genes and could be reservoirs f

153 rge largely due to transfer of virulence and antimicrobial resistance genes between bacteria, a proce

154 mpacts the community structure, function and antimicrobial resistance genes in lab-scale anaerobic di

155 MinION allowed successful identification of antimicrobial resistance genes in the draft assembly cor

156 show any correlation between the presence of antimicrobial resistance genes in the gut microbiota and

157 a and global dissemination of them and their antimicrobial resistance genes into animal and human pop

158 In contrast to virulence genotype, the antimicrobial resistance genes profiles varied between i

159 n, and contained a complement of chromosomal antimicrobial resistance genes similar to that of more r

160 enetic associations of the bacterium and its antimicrobial resistance genes through the course of an

161 asmids at that time explained the ability of antimicrobial resistance genes to disseminate among bact

162 e that temperate phages do not need to carry antimicrobial resistance genes to play a significant rol

163 In our dataset, antimicrobial resistance genes were common among human c

164 19 bacterial species, 5 Candida spp., and 4 antimicrobial resistance genes were studied over sequent

165 xy for integrons (which often carry multiple antimicrobial resistance genes), in the fecal microbiota

166 are toxigenic and often are associated with antimicrobial resistance genes, although they are not re

167 oaceticus-A. baumannii complex and to detect antimicrobial resistance genes.

168 , and the presence of virulence and acquired antimicrobial resistance genes.

169 ed significant diversity and high content of antimicrobial resistance genes.

170 ay and PCR for the carriage of virulence and antimicrobial resistance genes.

171 resistance plasmids harboring at least eight antimicrobial resistance genes.

172 typing, and identification of virulence and antimicrobial resistance genes.

173 We assessed the association between antimicrobial resistance genotype and phenotype and corr

174 Antimicrobial resistance has become an imminent concern

175 Over the past decade, antimicrobial resistance has become an increasingly comm

176 therapy is a mainstay of treatment, although antimicrobial resistance has drastically increased over

177 Antimicrobial resistance has thus been successfully expl

178 Thus, antimicrobial resistance has to be envisaged as an evolv

179 This is in part a result of antimicrobial resistance, highlighting the need to uncov

180 r potential dual contribution to fitness and antimicrobial resistance highlights their importance in

181 ping information and identify genes encoding antimicrobial resistance in 85 invasive serotype IV GBS

182 ntimicrobial use in food animals selects for antimicrobial resistance in bacteria, which can spread t

183 leading to very high and increasing rates of antimicrobial resistance in both hospital-acquired and c

184 During a routine surveillance project on antimicrobial resistance in commensal Escherichia coli f

185 n function that is an important regulator of antimicrobial resistance in E. faecalis.

186 the impact of RAGE on lung inflammation and antimicrobial resistance in fungal and bacterial pneumon

187 Wi and colleagues discuss the challenges of antimicrobial resistance in gonococci.

188 Predicting antimicrobial resistance in gram-negative bacteria (GNB)

189 Antimicrobial resistance in gram-positive bacteria remai

190 to be made against the increasing problem of antimicrobial resistance in human and veterinary medicin

191 The rise of antimicrobial resistance in human pathogenic bacteria ha

192 Furthermore, antimicrobial resistance in hvKP strains increased over

193 h expenditures were strongly correlated with antimicrobial resistance in low-income and middle-income

194 Emergence of antimicrobial resistance in microorganisms is a natural

195 Understanding drivers of antimicrobial resistance in MRSA isolates is important t

196 alization of case patients was predictive of antimicrobial resistance in MRSA isolates, but novel ris

197 The emergence and spread of antimicrobial resistance in Neisseria gonorrhoeae is glo

198 Gonorrhea treatment has been complicated by antimicrobial resistance in Neisseria gonorrhoeae.

199 epresents the basis for much of the acquired antimicrobial resistance in pathogenic bacteria.

200 Antimicrobial resistance in pathogenic gram-negative bac

201 tics is the most important factor predicting antimicrobial resistance in pneumococci.

202 In view of the alarming spread of antimicrobial resistance in the absence of new antibioti

203 Antimicrobial resistance in the MDR-PA keratitis isolate

204 iosis, outbreaks, and clinically significant antimicrobial resistance increased.

205 Many factors, including increasing antimicrobial resistance, increased human connectivity a

206 Antimicrobial resistance indices from existing but dispa

207 veloped a Web-based platform for aggregating antimicrobial resistance indices to support monitoring o

208 ating, analyzing, and disseminating regional antimicrobial resistance information.

209 in 4 subjects, we identified development of antimicrobial resistance, intrahost evolution, and strai

210 Antimicrobial resistance is a major issue in the Shigell

211 Antimicrobial resistance is a serious threat to public h

212 Antimicrobial resistance is an emerging concern.

213 Antimicrobial resistance is an important threat to inter

214 Knowledge of local antimicrobial resistance is critical for management of i

215 Antimicrobial resistance is currently one of the greates

216 Antimicrobial resistance is dominating scientific media.

217 The rapid identification of antimicrobial resistance is essential for effective trea

218 Slowing the evolution of antimicrobial resistance is essential if we are to conti

219 nt as a source and pathway for the spread of antimicrobial resistance is examined and key knowledge g

220 In an era in which antimicrobial resistance is increasing, judicious antimi

221 nd NTS are major causes of BSI in DRC; their antimicrobial resistance is increasing.

222 d: Our understanding of the global burden of antimicrobial resistance is limited.

223 ffectiveness of existing policies to control antimicrobial resistance is not yet fully understood.

224 exual partner(s) is complicated as macrolide antimicrobial resistance is now common in many countries

225 Unfortunately, the increasing problem of antimicrobial resistance is now recognized as a major pu

226 Antimicrobial resistance is one of the greatest threats

227 An intriguing opportunity to address antimicrobial resistance is represented by the inhibitio

228 reK, a determinant of envelope integrity and antimicrobial resistance, is required for long-term GIT

229 To combat infection and antimicrobial resistance, it is helpful to elucidate dru

230 tic era, the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR) was established to add

231 Salmonella antimicrobial resistance may result in bacteremia and po

232 enetrance confer high power to recover known antimicrobial resistance mechanisms and reveal a candida

233 mented an enterprise-wide collaboration, the Antimicrobial Resistance Monitoring and Research Program

234 almonella Enteritidis data from the National Antimicrobial Resistance Monitoring System and the Foodb

235 chia coli isolates collected by the National Antimicrobial Resistance Monitoring System between 2004

236 or Disease Control and Prevention's National Antimicrobial Resistance Monitoring System laboratory.

237 National Outbreak Reporting System, National Antimicrobial Resistance Monitoring System, and Foodborn

238 blood isolates, using data from the National Antimicrobial Resistance Monitoring System.

239 ethods for detection and characterization of antimicrobial resistance move from targeted culture and

240 infections has resulted in the emergence of antimicrobial resistance, necessitating alternative trea

241 trol strategies while the growing problem of antimicrobial resistance needs urgent action.

242 The N. gonorrhoeae Sequence Typing for Antimicrobial Resistance (NG-STAR) molecular typing sche

243 to global healthcare caused by an upsurge in antimicrobial resistance, no effort has been centered on

244 The theme of World Health Day, 2011, was "antimicrobial resistance: no action today and no cure to

245 ing threats-risks to global health security, antimicrobial resistance, non-communicable diseases, and

246 of the major mechanisms involved in multiple antimicrobial resistance of Bcc pathogens.

247 Antimicrobial resistance of iNTS against most available

248 Adaptations that enable antimicrobial resistance often pose a fitness cost to th

249 o be useful in better understanding acquired antimicrobial resistance or for screening antimicrobial

250 gulase-mediated biofilms exhibited increased antimicrobial resistance over time (>48 hours) but were

251 ne dysentery has been followed by reports of antimicrobial resistance over time.

252 in development to treat the rising threat of antimicrobial resistance, particularly in Gram-negative

253 Antimicrobial resistance, particularly in pathogens such

254 were associated with significantly different antimicrobial resistance patterns in comparison to all g

255 We reviewed clinical features, outcomes, and antimicrobial resistance patterns in invasive NTS infect

256 Surveillance of M. genitalium prevalence and antimicrobial resistance patterns is urgently needed.

257 bloodstream infection (CLABSI) pathogens and antimicrobial resistance patterns reported from oncology

258 Patients were interviewed and antimicrobial resistance patterns were tested among isol

259 vasive pneumococci, and invasive pneumococci antimicrobial resistance patterns, in India.

260 ce indices to support monitoring of regional antimicrobial resistance patterns.

261 the molecular genetic basis of 99.8% of the antimicrobial resistance phenotypes of the isolates, hig

262 Determination of the molecular structure of antimicrobial resistance plasmids at that time explained

263 ug resistant S. enterica serovar Heidelberg, antimicrobial resistance plasmids from five isolates wer

264 Antimicrobial resistance poses a growing threat to publi

265 Conclusions and Relevance: Antimicrobial resistance poses significant challenges fo

266 ical diseases ( pound184 million, 7.1%), and antimicrobial resistance ( pound96 million, 3.7%).

267 Antimicrobial resistance profiles and fine clonal struct

268 nly strain with both extensive virulence and antimicrobial resistance profiles.

269 Pathogen profile, antimicrobial resistance rates, and CLABSI incidence rat

270 pared to ASP alone, even in a setting of low antimicrobial resistance rates.

271 Antimicrobial resistance remains a serious and growing h

272 of E. faecalis mutants exhibiting defects in antimicrobial resistance revealed that IreK, a determina

273 microorganisms is a natural phenomenon, yet antimicrobial resistance selection has been driven by an

274 Complementary approaches to antimicrobial resistance surveillance are needed.

275 An annual update of antimicrobial resistance surveillance data of uropathoge

276 istance data were obtained from the European antimicrobial Resistance Surveillance Network and outpat

277 In Europe, although the European Antimicrobial Resistance Surveillance Network provides a

278 Improvement of national antimicrobial resistance surveillance systems and better

279 Saharan Africa lacks diagnostic capacity and antimicrobial resistance surveillance.

280 The Trans-Atlantic Task Force on Antimicrobial Resistance (TATFAR) in 2015 was tasked wit

281 publication, the Transatlantic Task Force on Antimicrobial Resistance (TATFAR) summarized the key are

282 nucleic acid amplification testing including antimicrobial resistance testing in men with symptoms of

283 nd were significantly more likely to exhibit antimicrobial resistance than isolates from MSW (P < 0.0

284 appropriate use of antimicrobials and combat antimicrobial resistance, the workgroup provides recomme

285 e the significant potential consequences for antimicrobial resistance, there has been no quantitative

286 n new antibiotic development and the rise in antimicrobial resistance, there is an urgent need to exa

287 Approximately 20% of blood isolates had antimicrobial resistance to a first-line treatment agent

288 Antimicrobial resistance to traditional antibiotics is a

289 The Study for Monitoring Antimicrobial Resistance Trends (SMART) global surveilla

290 Increasing antimicrobial resistance underscores the potential impor

291 This study examines the prevalence, antimicrobial resistance, virulence, and genetic diversi

292 ere predominately associated with additional antimicrobial resistances, virulence, and serotype conve

293 of patients infected with the same organism, antimicrobial resistance was associated with higher char

294 ditional essentiality of individual genes to antimicrobial resistance was evaluated in an epidemic mu

295 ctants, on microbial community structure and antimicrobial resistance was investigated using three ae

296 adverse events nor the rate of emergence of antimicrobial resistance was lower with the shorter regi

297 Genes associated with antimicrobial resistance were differentially distributed

298 oordination of surveillance systems of human antimicrobial resistance with animal surveillance system

299 national level is positively correlated with antimicrobial resistance within developed countries.

300 remove the selection pressure that maintains antimicrobial resistance within populations.