ライフサイエンスコーパス: antinuclear antibody

1 ue, vague cognitive defects, and a low titer antinuclear antibody.

2 Three patients had a positive antinuclear antibody.

3 Sera were evaluated for the presence of antinuclear antibodies.

4 ive autoimmune B cells to produce pathogenic antinuclear antibodies.

5 , P-ANCA was associated with the presence of antinuclear antibodies.

6 thickening, and high titers of anti-DNA and antinuclear antibodies.

7 disease, such as arthritis, lymphopenia, or antinuclear antibodies.

8 hermore, about one-third of the mice develop antinuclear antibodies.

9 mes clinically detectable by the presence of antinuclear antibodies.

10 ), that are characterized by the presence of antinuclear antibodies.

11 c mice and was accompanied by an increase in antinuclear antibodies.

12 omenon (RP) and the presence of SSc-specific antinuclear antibodies.

13 ortion of autoreactive antibodies, including antinuclear antibodies.

14 immunofluorescence studies that demonstrate antinuclear antibodies.

15 tis and small joint involvement, and express antinuclear antibodies.

16 mphoid organs spontaneously develop specific antinuclear antibodies.

17 ts produced in vitro anti-GBM antibodies and antinuclear antibodies.

18 the majority of MZ twins are concordant for antinuclear antibodies.

19 cular dryness in the presence of circulating antinuclear antibodies.

20 increased in humans and mice, combined with antinuclear antibodies.

21 Sera from 9/12 patients containing antinuclear antibodies (10/12 meeting diagnostic criteri

22 fold capillaroscopy and laboratory tests for antinuclear antibodies (ANA) and ANA subsets were obtain

23 ficient in this molecule develop spontaneous antinuclear antibodies (ANA) and fatal glomerulonephriti

24 say were compared with those of an assay for antinuclear antibodies (ANA) and with the severity of th

25 Antinuclear antibodies (ANA) are important in diagnosis

26 Screening only for antibodies to actin and antinuclear antibodies (ANA) failed to establish the dia

27 cted mixtures in relation to the presence of antinuclear antibodies (ANA), a widely used biomarker of

28 A majority of these autoantibodies are true antinuclear antibodies (ANA), and 50% of the ANAs are al

29 active protein, leukocyte count, presence of antinuclear antibodies (ANA), presence of human leukocyt

30 (NCWS), and investigated whether they carry antinuclear antibodies (ANA).

31 A locus Adnz1 on chromosome 4 was linked to antinuclear antibody (ANA) and anti-double stranded DNA

32 Here we report high titers of spontaneous antinuclear antibody (ANA) in C4(-/)- mice.

33 suggests that patients with in vivo speckled antinuclear antibody (ANA) patterns have high titers of

34 associations between mercury biomarkers and antinuclear antibody (ANA) positivity and titer strength

35 IA patients, including female preponderance, antinuclear antibody (ANA) positivity, and certain human

36 three positive answers were to attend for an antinuclear antibody (ANA) test; and those testing posit

37 orescence methods with bead-based assays for antinuclear antibody (ANA) testing is a new clinical opt

38 ected over a 5-year period in a rheumatology antinuclear antibody (ANA) testing laboratory.

39 A were identified, and serologic studies for antinuclear antibody (ANA), rheumatoid factor, and antib

40 DNA) and double-stranded DNA (anti-dsDNA) in antinuclear antibody (ANA)-positive type 1 autoimmune he

41 ic arthritis, spinal pain, fever, psoriasis, antinuclear antibodies [ANA], and rheumatoid factor).

42 E Disease Activity Index (SLEDAI), serology (antinuclear antibody [ANA] and anti-double-stranded (ds)

43 case-control study confirmed the presence of antinuclear antibodies (ANAs) and other autoantibodies i

44 Two outstanding questions concerning antinuclear antibodies (ANAs) in lupus involve their pat

45 nt (SLC-/-) mice harbored elevated levels of antinuclear antibodies (ANAs) in their serum and showed

46 s (SLE) is characterized by high-avidity IgG antinuclear antibodies (ANAs) that are almost certainly

47 The presence of antinuclear antibodies (ANAs) was determined using indir

48 ti-citrullinated protein antibodies (ACPAs), antinuclear antibodies (ANAs), anti-tissue transglutamin

49 ototypic autoimmune disease characterized by antinuclear antibodies (ANAs), including pathogenic spec

50 bers according to the presence or absence of antinuclear antibodies (ANAs), the ANA staining patterns

51 in forming a pre-BCR, leads to production of antinuclear antibodies (ANAs).

52 yed a breached immune tolerance and secreted antinuclear antibodies (ANAs).

53 Antinuclear antibodies and AHAs, but not ssDNA abs, were

54 els, E6446 slowed development of circulating antinuclear antibodies and had a modest effect on anti-d

55 omparable in patients with and those without antinuclear antibodies and in both early- and late-onset

56 Female NZB/WF1 mice produce high titers of antinuclear antibodies and invariably succumb to severe

57 between fibromyalgia patients with low titer antinuclear antibodies and primary SS remains difficult.

58 Serum IgE, rheumatoid factor, and antinuclear antibodies and skin sensitivity to common al

59 itis, and laboratory abnormalities including antinuclear antibody and rheumatoid factor positivity.

60 SLE was based on the presence of arthritis, antinuclear antibodies, and double-stranded DNA, and a c

61 ore transplant of idiopathic cardiomyopathy, antinuclear antibodies, and HLA-B8, DR3 haplotypes.

62 ted diagnoses, discoid lupus, positivity for antinuclear antibodies, and/or false-positive syphilis t

63 Smooth muscle antibody, antinuclear antibody, and antibody to liver/kidney micro

64 udies were similar, including positivity for antinuclear antibodies, anti-native DNA, and anti-double

65 Antinuclear antibodies are a hallmark feature of general

66 Most polyreactive and antinuclear antibodies are removed from the human antibo

67 etric analysis of salivary glands, and serum antinuclear antibody assay were performed to assess vari

68 rbent assay, autoantigen proteome array, and antinuclear antibody assay.

69 These sera contained antinuclear antibodies, but lacked antibodies to double-

70 ed with the presence of rheumatoid factor or antinuclear antibodies, but not with positive allergen s

71 ccinee (n = 14), and one specimen containing antinuclear antibody cross-reacted with the assay.

72 Loci linked with anti-gp70 compared with antinuclear antibodies demonstrated the strongest linkag

73 to the drug developed in 8% of patients, and antinuclear antibodies developed in 2%.

74 en patients with (Ab(+)) and without (Ab(-)) antinuclear antibody during adulthood and an age- and se

75 This study explores the antinuclear antibody fine specificities and underlying c

76 ss offspring uncovered 5 suggestive loci for antinuclear antibody formation, consisting of 3 dominant

77 Sera containing antinuclear antibodies from patients with systemic lupus

78 regimen eluted severalfold more IgG and IgM antinuclear antibodies from the kidneys of nephritic SNF

79 et of 321 serologically active SLE patients (antinuclear antibodies >/=1:80 and/or anti-double-strand

80 ly, H2(d/z) (compared with H2(d/d)) enhanced antinuclear antibodies in a coordinate fashion but did n

81 ther compounded by the finding of "positive" antinuclear antibodies in a high percent of the general

82 ssociations between selected xenobiotics and antinuclear antibodies in the National Health and Nutrit

83 hocytic infiltration of the lacrimal glands, antinuclear antibodies in the serum, and elevated titer

84 serum anti-CCP, rheumatoid factor (RF), and antinuclear antibody in a defined sample of 9,988 of bla

85 positive results because of the presence of antinuclear antibodies, is not a specific marker of anti

86 lambda(s) 11.0), anemia (lambda(s) 1.7), and antinuclear antibodies (lambda(s) 1.3).

87 Serologic markers showed increased IgG and antinuclear antibody levels in seven of 12 patients.

88 ers such as serum immunoglobulin G (IgG) and antinuclear antibody levels were available in 12 patient

89 Sera were tested using immunofluorescent antinuclear antibodies on HEp-2 cell slides, by anti-RNA

90 -like syndrome with joint manifestations and antinuclear antibodies: one had anti-RNP and antiphospho

91 sy-proven lupus nephritis in the presence of antinuclear antibodies or anti-double-stranded DNA antib

92 n-experienced autoreactive B cells producing antinuclear antibody or rheumatoid factor and exhibit th

93 All six patients had positive antinuclear antibody or smooth muscle antibody titers.

94 )/L: OR 2.15, 95% CI 1.63-2.83), presence of antinuclear antibodies (OR 2.87, 95% 1.57-5.24), and tre

95 ficantly associated with: i/ the presence of antinuclear antibodies (OR=5.9, P=0.04) ii/ a more sever

96 Analysis of his serum was negative for antinuclear antibody (or ANA), cytoplasmic antineutrophi

97 s (P = 0.01) and to have increased titers of antinuclear antibodies (P = 0.04).

98 before the diagnosis, were found later than antinuclear antibodies (P=0.06) and earlier than anti-nu

99 e weakness and congestive heart failure, was antinuclear antibody positive and had muscle biopsy find

100 Five children were antinuclear antibody positive.

101 on between the effects of rheumatoid factor, antinuclear antibodies, positive skin allergen tests, or

102 We selected 196 antinuclear antibody-positive adult SLE patients (age >

103 r, randomized, placebo-controlled trial, 819 antinuclear antibody-positive or anti-double-stranded DN

104 Seven antinuclear antibody-positive, nephritic female (SWR x N

105 most frequent combination was arthritis and antinuclear antibody positivity followed by malar rash a

106 llin 1 antibodies and active skin disease or antinuclear antibody positivity were found.

107 Antinuclear antibody positivity, early onset of disease,

108 subjects in this cohort had similar rates of antinuclear antibody positivity, whereas lupus-specific

109 We further demonstrate antinuclear antibody production is influenced by the pre

110 However, antinuclear antibody production was increased compared w

111 dermatomyositis, the mice developed a strong antinuclear antibody response, characteristic of autoimm

112 ash, autoimmune thyroiditis, the presence of antinuclear antibodies, sinopulmonary infections, and co

113 range of autoantibodies (rheumatoid factor, antinuclear antibody, smooth muscle autoantibody, mitoch

114 Antinuclear antibody status was a predictor for the deve

115 Male sex, independent of age or antinuclear antibody status, is associated with increase

116 Antinuclear antibodies test results were negative.

117 The indirect fluorescence antinuclear antibody test on Hep-2 cells demonstrated an

118 Routine antinuclear antibody testing has a low positive predicti

119 ccordingly, the positive predictive value of antinuclear antibody testing in diagnosing SLE in a pati

120 is needed to establish the value of routine antinuclear antibody testing in patients with uveitis.

121 The positive predictive value of routine antinuclear antibody testing was 2.9% (95% CI, 2.65%-3.1

122 Routine antinuclear antibody testing, for example, is not recomm

123 e negative for anti-SSA/Ro, anti-SSB/La, and antinuclear antibodies than women (36% men vs 11% women,

124 up (71.5%) of serologically active patients (antinuclear antibody titer >/=1:80 and/or anti-double-st

125 ents with lcSSc or Raynaud's syndrome and an antinuclear antibody typical of lcSSc as part of the bas

126 elet volume, positive rheumatoid factor, and antinuclear antibodies were all significantly more preva

127 s syndrome with high levels of antineural or antinuclear antibodies were infused bilaterally into the

128 Antinuclear antibodies were present at low titers in 4 p

129 Antinuclear antibodies were present in 4 of 55 sera test

130 Antinuclear antibodies were present in 78 percent (at a

131 Antinuclear antibodies were present in all patients.

132 nofluorescence immunoreactants and low titer antinuclear antibodies were variably present.