ライフサイエンスコーパス: antioxidative

1 pes, olive and broccoli wastes, the relative antioxidative abilities of lettuces cultivated in greenh

2 red to be H2O2-dependent with an increase in antioxidative ability for H-SeB.

3 rious foods and beverages, mechanisms of its antioxidative action have not been fully clarified.

4 results have important implications for the antioxidative actions of *NO and its effects on cellular

5 late pancreatic insulin secretion or through antioxidative actions.

6 Herein we compared antioxidative activities (AA) of 25 free L-amino acids (

7 itions delayed pericarp browning, maintained antioxidative activities and biochemical characteristics

8 Antioxidative activities of phenolic compounds (caffeic

9 suggesting that they will exhibit comparable antioxidative activities.

10 n pericarp browning, biochemical quality and antioxidative activities.

11 f sugars, organic acids, total phenolics and antioxidative activity have been evaluated among three d

12 roducing Pacific hake hydrolysates with good antioxidative activity in various assays and similar eff

13 ide fractions (>5kDa, 3-5kDa and <3kDa) with antioxidative activity obtained from a cod protein hydro

14 on the chemical stability of SSO and on the antioxidative activity of 40muM alpha-tocopherol in SSO

15 Thus, we describe a novel antioxidative activity of a previously characterized bio

16 tigates changes in the anti-inflammatory and antioxidative activity of anthocyanins from purple basil

17 of intact resorcinol is proportional to the antioxidative activity of HOCl scavengers.

18 The results indicate that the antioxidative activity of KFEE is defined by the relativ

19 In the current study, the antioxidative activity of KFEE, which contains polypheno

20 To measure antioxidative activity of plant extracts we used three a

21 The antioxidative activity of the crude hydrolysates and the

22 Since no clear correlation between the antioxidative activity of the FPH and the course of lipi

23 ht peptides thus seemed to contribute to the antioxidative activity of the peptide fractions, and Tyr

24 position, functional properties and in vitro antioxidative activity of the peptidic fraction of carot

25 ckberry leaf extract exhibited cytotoxic and antioxidative activity on human colon cancer cells.

26 c acid-rich fraction, showed the most potent antioxidative activity whereas the polymeric and anthocy

27 Cholesterol acceptor capacity and antioxidative activity, representing two key cardioprote

28 As markers for antioxidative activity, the intracellularly generated RO

29 activity like antibacterial, antifungal, and antioxidative activity.

30 Compound 13 was found to pose an antioxidative activity.

31 probiotic L. rhamnosus strain GG had potent antioxidative activity: dampening reactive oxygen specie

32 Furthermore, in vivo treatment with the antioxidative agent N-acetyl-L-cysteine resulted in reve

33 that can function as an antiinflammatory and antioxidative agent, and as such, it may have atheroprot

34 Interrelations with other antioxidative agents and oxidative stressors, such as sm

35 lcysteine and N-t-butyl-alpha-phenylnitrone, antioxidative agents such as catalase, superoxide dismut

36 to inhibitors of CYP2E1 and to a variety of antioxidative agents.

37 The transepithelial transport of an antioxidative and ACE inhibitory peptide, VLPVPQK (named

38 n the endothelial cells created by excess of antioxidative and anti-inflammatory agents NAC and mito-

39 e such possible process, a deficiency of the antioxidative and anti-inflammatory enzyme heme oxygenas

40 ed polyketides from P. malabarica as natural antioxidative and anti-inflammatory functional food ingr

41 luding proinflammatory cytokines, and exerts antioxidative and anti-inflammatory functions.

42 ntake of dietary flavonoids, known for their antioxidative and anti-inflammatory properties, affects

43 n E isoform gamma-tocotrienol possesses both antioxidative and anti-inflammatory properties, we sough

44 argely involved in xenobiotic metabolism and antioxidative and anti-inflammatory protection, as well

45 adipose-derived cytokine that may act as an antioxidative and anti-inflammatory protein.

46 a high-fat dietary habit via regulations of antioxidative and anti-inflammatory responses.

47 ession of Trx--the redox protein with potent antioxidative and antiapoptotic properties--may play a p

48 im of this study was to evaluate and compare antioxidative and antihypertensive activities of Longiss

49 Pig meat showed antioxidative and antihypertensive activities, heat trea

50 Antioxidative and antihypertensive bioactive peptides we

51 functional food since it is a good source of antioxidative and antihypertensive peptides.

52 organic solvent extract of ginger possesses antioxidative and antiinflammatory properties.

53 exert significant endothelial protection by antioxidative and antinitrative effects.

54 Antioxidative and antiproliferative assays demonstrated

55 ouse and human studies have demonstrated the antioxidative and atheroprotective effects of PON1.

56 Nrf2, in turn, induces a number of antioxidative and carcinogen-detoxifying enzymes.

57 Nrf2, a transcriptional factor that induces antioxidative and cytoprotective pathways.

58 proapoptotic effects and that .NO exerts an antioxidative and cytoprotective role.

59 lular defense by initiating transcription of antioxidative and detoxification genes.

60 ed insulin biosynthesis can overwhelm the ER antioxidative and folding capacity, causing an imbalance

61 Antioxidative and functional properties of protein hydro

62 s are of great current interest due to their antioxidative and possible anticarcinogenic activities.

63 etary catechins are phytochemicals with both antioxidative and prooxidative stress properties.

64 as immunomodulatory interleukin 6 as well as antioxidative and proproliferative molecules (HMOX1, VEG

65 In contrast, an increase in antioxidative and reducing capacity of stored cakes was

66 icular, the changes in antioxidants content, antioxidative and reducing capacity, and Maillard reacti

67 nes were present, leptin attenuated both the antioxidative and the lipogenic effects of insulin by 50

68 , and has been shown to have osmoregulatory, antioxidative, antiapoptotic, anti-inflammatory, and ant

69 -pressed oils contained compounds that exert antioxidative, antimicrobial, acetylcholinesterase inhib

70 injury in vivo but has minimal effect on the antioxidative/antinitrative protection of adiponectin.

71 ts, among them, antimicrobial, antidiabetic, antioxidative, antiobesity and antihypertensive effects.

72 In general, the various antioxidative assays correlated well with the total phen

73 However, in some of the antioxidative assays some species with low total phenoli

74 Antioxidative bioactive peptide was successfully identif

75 e relative indices enables the comparison of antioxidative capacities obtained in various studies.

76 Plasma total antioxidative capacities were approximately 37% normal i

77 found to be positively correlated with total antioxidative capacity and inversely related to the RDS

78 ars followed by assessment of their in vitro antioxidative capacity by LC-MS and oxidation/reduction

79 chimeric Ag receptor (CAR) to increase their antioxidative capacity by metabolizing H2O2.

80 d macrophages, and platelets, as well as the antioxidative capacity of different antioxidants.

81 ility at different pH, thermal stability and antioxidative capacity of glycated WP were increased, es

82 This study aimed at unravelling the antioxidative capacity of low molecular weight compounds

83 is that TCM cells possess relatively greater antioxidative capacity than TEM cells.

84 as obtained by the systemic elevation of the antioxidative capacity through daily administration of R

85 sponse element (ARE) regulates intracellular antioxidative capacity to combat oxidative stress.

86 Subjects who had ACS had higher HII (less antioxidative capacity) compared with controls (1.57 vs.

87 tracellular oxidant production outweighs the antioxidative capacity, lies at the basis of many diseas

88 y high to have a significant impact on total antioxidative capacity, the compound itself or a structu

89 ne (AFMK) was investigated for its potential antioxidative capacity.

90 ed with reduced cancer risk because of their antioxidative capacity.

91 PCs and thus, can alter their scavenging and antioxidative capacity.

92 n of GSH by NO and oxygen may be part of the antioxidative cellular defense system.

93 ontains high levels of anti-inflammatory and antioxidative compounds such as ginnalins, but little is

94 The antioxidative compounds were extracted by ultrasonic tre

95 Coincidently, antioxidative compounds were not induced in infected MtR

96 NI and BEN showed mild toxicity at effective antioxidative concentrations derived from DPPH and ABTS

97 d changes in nerve function, metabolism, and antioxidative defense are corrected by the dose of ARI (

98 was achieved due to upregulation of the key antioxidative defense enzyme activities rather than chan

99 sual and generally unexpected small group of antioxidative defense genes appear to have increased exp

100 A small group of antioxidative defense genes were found in this populatio

101 Many genes that are frequently considered antioxidative defense genes, including most of the GSH p

102 mplified expression of only a few additional antioxidative defense genes.

103 ified superoxide dismutase 2 (SOD2)-mediated antioxidative defense in the genetic allele's susceptibi

104 Antioxidative defense systems are not mobilized as expec

105 lasts contains multiple proteins involved in antioxidative defense, protein folding, and repair.

106 ione, suggesting a general compromise of the antioxidative defense.

107 nt and lower expression of genes involved in antioxidative defenses and signaling, suggesting that th

108 lly linked to maintain redox homeostasis and antioxidative defenses at normal (37 degrees C) temperat

109 tein levels, with corresponding induction of antioxidative defenses in OLs exposed to cytokines via A

110 However, analyses of the antioxidative defenses indicated that catalase activity

111 rf2 transcription factor and upregulation of antioxidative defenses occurs in astrocytes infected wit

112 e indicates that exercise training evokes an antioxidative effect in CHF.

113 The antioxidative effect of lipophilized caffeic acid was as

114 The antioxidative effect of sitosterol at 1, 2 and 5% levels

115 ination of water, may be responsible for the antioxidative effect of sitosterol at frying temperature

116 Atorvastatin exerted a profound antioxidative effect on vascular fatty lesions.

117 and necrosis in a manner consistent with its antioxidative effect.

118 ity of stripped soybean oil (SSO) and on the antioxidative effectiveness of alpha-tocopherol in SSO.

119 has been associated with both oxidative and antioxidative effects in vivo.

120 low total phenolic content also showed good antioxidative effects indicating that some other co-extr

121 nce assay was used to evaluate any potential antioxidative effects of ODQ.

122 gests that NaPB exerts anti-inflammatory and antioxidative effects via inhibition of these small G pr

123 shoots could have contributed towards their antioxidative effects.

124 ynaptic and extrasynaptic) NMDARs induced no antioxidative effects.

125 ellular energy metabolism and that may exert antioxidative effects.

126 Analysis of classic antioxidative enzyme activities showed little change bet

127 including catalase, GSH peroxidase and other antioxidative enzyme activities, cell number and cell vi

128 cellular H2O2 production with the change in antioxidative enzyme activity, and the restoration of ch

129 st, training increased the expression of the antioxidative enzyme genes by approximately 100%.

130 hology of cerebral malaria, we show that the antioxidative enzyme glutathione reductase (GR) is inact

131 of PARP-1 and topoisomerase IIbeta, loss of antioxidative enzyme induction and attenuated protection

132 RE (electrophile response element)-regulated antioxidative enzyme QR.

133 correlates with increased expression of the antioxidative enzyme quinone reductase (QR).

134 Superoxide dismutase 2 (SOD2) is a crucial antioxidative enzyme that is found in mitochondria.

135 idoreductase (AOR) from the rat is a phase 2/antioxidative enzyme that is known to catalyze the reduc

136 s further characterized as an Nrf2-regulated antioxidative enzyme that reduces carbon-carbon double b

137 Correspondingly, the expression of an antioxidative enzyme, 2-Cysteine peroxiredoxin (BxPrx),

138 hat increasing the activities of these major antioxidative enzymes above wild type levels does not de

139 -1 to the EpRE resulting in the induction of antioxidative enzymes and subsequent protection against

140 ncreased HO activity, which induces arterial antioxidative enzymes and vasoprotection in a mouse and

141 properties of nanofactories that consist of antioxidative enzymes encapsulated in metal-organic fram

142 O1 and NQO2 to investigate the role of these antioxidative enzymes in a two-stage model of inflammato

143 Lead is known to induce phytochelatins and antioxidative enzymes in vetiver; however, the overall i

144 onal role of ERbeta-mediated upregulation of antioxidative enzymes indicated protective effects again

145 NADPH oxidase, as well as the suppression of antioxidative enzymes involved in ROS clearance, the und

146 addition, the intracellular distribution of antioxidative enzymes may be modulated to regulate or fa

147 ollowing observations: (i) Overexpression of antioxidative enzymes retards the age-related accrual of

148 mes Cyp2e1 and Cyp4a14, higher expression of antioxidative enzymes Sod2, Gpx1, and Nqo1, without chan

149 The overexpression of antioxidative enzymes such as CuZn-superoxide dismutase

150 lear factors essential for the expression of antioxidative enzymes such as GPX3 and catalase.

151 e oxygen species, which can be detoxified by antioxidative enzymes, including catalases.

152 timulation of the activities of a variety of antioxidative enzymes, reduction in proinflammatory cyto

153 ucible genes included known detoxication and antioxidative enzymes.

154 medicinal/pharmaceutical applications of its antioxidative features, this compound in planta and its

155 the first report showing that TcSOD2 has an antioxidative function and demonstrates that T. castaneu

156 The antioxidative function of carnosol relies on another mec

157 To investigate the mechanisms underlying the antioxidative function of DJ-1 in relation to SOD1 activ

158 nterest in the roles of vitamin E beyond its antioxidative function.

159 Thus antioxidative gelatin hydrolysate with negligible undesi

160 Specifically, enhanced antioxidative gene expression and the lack of differenti

161 observed in DF regions, notably an enhanced antioxidative gene expression.

162 egulation of PARP-1 attenuates TOT-dependent antioxidative gene induction.

163 r role for Nrf2 and ERalpha in TOT-dependent antioxidative gene regulation.

164 iption factor that up-regulates a battery of antioxidative genes and cytoprotective enzymes that cons

165 pressing the transcription of Nrf2-dependent antioxidative genes.

166 tive oxygen species (ROS), which trigger the antioxidative glutathione (GSH) response necessary to bu

167 ecause selenium is an essential component of antioxidative glutathione peroxidases (GPx).

168 The antioxidative GSH pathway thus plays an unexpected role

169 rotein isolate was hydrolyzed to an in vitro antioxidative hydrolysate, followed by transglutaminase-

170 IL-6 pretreatment induced the antioxidative injury proteins, ref-1 and GPX1, decreased

171 results together, we have uncovered a novel antioxidative mechanism by which PML regulates cellular

172 A ubiquitous antioxidative mechanism for regulating cellular redox ba

173 .g. at physiological pH) SPLET is the likely antioxidative mechanism of 5CQA with extremely high rate

174 It was found that SET-PT is not a plausible antioxidative mechanism of 5CQA.

175 ults suggest that an upregulation in central antioxidative mechanisms and suppressed central prooxida

176 that long-term E2 treatment improves CHF by antioxidative mechanisms that involve the upregulation o

177 ect on autonomic activity in CHF via central antioxidative mechanisms.

178 for thermodynamic consideration of the major antioxidative mechanisms: HAT (Hydrogen Atom Transfer),

179 meroterpenoids might serve as potential lead antioxidative molecules for use in pharmaceutical and fo

180 Additional in vitro studies showed antioxidative neuroprotective effects as well as the abi

181 city, anti-Alzheimer's disease activity, and antioxidative/neuroprotective effects.

182 FBS and RD hydrolysates have a potential as antioxidative neutraceutical ingredients.

183 -exposed, NO-exhausted GSNO produced neither antioxidative nor neuroprotective effects, which indicat

184 r factor erythroid 2-related factor 2 (Nrf2) antioxidative pathway.

185 cleotide biosynthesis, and the GSH-dependent antioxidative pathway.

186 esponse, we examined several major oxidative/antioxidative pathways and found that atheroprotective f

187 ioxidant that functions independent of other antioxidative pathways in the cellular defense against R

188 There is high potential that antioxidative peptides from rice bran might also be prod

189 Peroxiredoxin 4 (Prdx4), an ER-specific antioxidative peroxidase can utilize luminal H2O2 as dri

190 ulin p<0.0001, tropomyosin alpha4 p=0.0108), antioxidative (peroxiredoxin 2 p=0.0092), and anti-infla

191 maximize possible health benefits of cereal antioxidative phytochemicals.

192 arboxyl group) and molecular conformation in antioxidative potency of dihydrocaffeic acid (DHCA) and

193 ls in the creation of the nutritional value, antioxidative potential and stability of the lipid fract

194 The antioxidative potential of applied teas was significant

195 Different antioxidative potential of isolated peptide were assesse

196 For some vegetables, an increase in the antioxidative potential was observed as a result of cook

197 ly used as a source of polyphenols with high antioxidative potential, as well as fiber; thus introduc

198 Oregano and rosemary showed also some antioxidative potential.

199 e inadequate in vitro and in vivo studies on antioxidative potentials of fermented versus unfermented

200 nal redox balance by assessing oxidative and antioxidative processes in kidneys of brain-dead rats af

201 T. arduini extract could be responsible for antioxidative/prooxidative mechanisms and would help in

202 These included two proteins with antioxidative properties (peroxiredoxin and superoxide d

203 rate-limiting step in heme degradation, has antioxidative properties and protects cells from various

204 PC diet were also evaluated in view of their antioxidative properties for lipoproteins and cholestero

205 Antioxidative properties for raw vegetables were obtaine

206 In this work, we sought to determine the antioxidative properties of a lipid-soluble derivative o

207 iably invoked when explaining the biological antioxidative properties of beta-carotene.

208 The antioxidative properties of E2 were also associated with

209 n this study, we investigated, in vitro, the antioxidative properties of fractions obtained from a co

210 The antioxidative properties of Pacific hake hydrolysates an

211 y (ORAC) assay has been used to quantify the antioxidative properties of phytonutrients in fruit and

212 has become a standard method to quantify the antioxidative properties of phytonutrients in fruit and

213 ontaining amino acids might be attributed to antioxidative properties of pyrroles or amino acids.

214 Changes in chemical composition and antioxidative properties of rye ginger cakes during thei

215 ve effects are possibly mediated through the antioxidative properties of selenoenzymes.

216 In the current work, we studied the antioxidative properties of six fruits: rosehip, chokebe

217 omponents have been shown to differ in their antioxidative properties, and their localisation in emul

218 ed by other forms of tocopherol with similar antioxidative properties, have raised interest in the ro

219 s (diCQAs) have been found to possess marked antioxidative properties.

220 heir catalytic chain-breaking and preventive antioxidative properties.

221 Ginkgo biloba leaves, has been shown to have antioxidative properties.

222 t potentially be nutraceutical peptides with antioxidative properties.

223 can contribute to the antimutagenic and the antioxidative property of Allium vegetables.

224 These findings suggest that the antioxidative property of L. guynianum is may be related

225 mma-induced IL-27 production and AHR via its antioxidative property.

226 oxygen species levels, indicating increased antioxidative protection, as well as lower sensitivity t

227 thway in lungs, suggesting that loss of this antioxidative protective response is a key factor in the

228 13, member A (FAM213A), a peroxiredoxin-like antioxidative protein, was repressed transcriptionally b

229 GAA induces antioxidative response and inhibits accumulation of exce

230 (SESN2) is found to mediate GAA function in antioxidative response and RPE survival upon oxidative s

231 ngs identify repression of the NRF2-mediated antioxidative response as a key contributor to the prema

232 spholipid oxidation products that induced an antioxidative response dependent on the transcription fa

233 ROS is not important in the induction of the antioxidative response or cellular death by ATO.

234 nt increase in SIRT1 expression generates an antioxidative response that contributes to reactive oxyg

235 peripheral and lumenal proteins involved in antioxidative response, including peroxiredoxins, m-type

236 The pattern was consistent with a strong antioxidative response, particularly of genes activated

237 Despite the activation of this antioxidative response, ROS may not be important in ATO-

238 We hypothesized that stimulating opposing antioxidative responses in astrocytes, as well as neuron

239 1, which further decreases Nrf2 function and antioxidative responses to S Typhimurium infection, even

240 rotein 24 (mVP24) as a modulator of the host antioxidative responses, but the molecular mechanism rem

241 ciated with keratinocyte differentiation and antioxidative responses, while inhibiting the expression

242 itochondrial dysfunction, and Nrf2-modulated antioxidative responses.

243 acts (SeB) and selenocompounds on growth and antioxidative status in human colon cancer cells was inv

244 An antioxidative stress array analysis of neurons treated w

245 e previously reported that the expression of antioxidative stress enzymes is upregulated by trans-hyd

246 ern, possibly due to stimulation of cellular antioxidative stress mechanisms.

247 due to AHR-regulated activation of the NRF2 antioxidative stress pathway.

248 GSH-spermidine bioconjugate, involved in the antioxidative stress protection system of parasitic prot

249 Expression of the antioxidative stress protein heme oxygenase-1 (HO-1) was

250 ch with higher affinity and stimulate higher antioxidative stress response element (ARE) reporter act

251 tumorigenesis in mice, but its roles in the antioxidative stress response or its involvement in neur

252 or suppressor HACE1 plays a role in the NRF2 antioxidative stress response pathway and in neurodegene

253 eased oxidative stress in brain and that the antioxidative stress response was impaired.

254 2 (NRF2), a master regulator of the cellular antioxidative stress response, is deregulated in both ca

255 y light-inducible proteins, ion homeostasis, antioxidative stress, detoxification, and biosynthetic e

256 Its mechanisms are believed to be related to antioxidative stress.

257 ase in particular, and the native biological antioxidative system in skin in general.

258 alkylate glutathione, thereby inhibiting the antioxidative system of the cell, whereas the iron speci

259 me catalase, which is part of the biological antioxidative system present in skin.

260 e, the activity of enzymes involved in plant antioxidative system via ascorbate-glutathione cycle, as

261 tes that T. castaneum may use an alternative antioxidative system when the SOD2-based system fails.

262 The complexity of plant antioxidative systems gives rise to many unresolved ques

263 interactions between the complex, networking antioxidative systems in restricting ROS accumulation or

264 The different soluble antioxidative systems, in particular peroxiredoxins, acc

265 fied genes do not appear to be involved with antioxidative systems, reflecting the complexity of the

266 ife forms were obliged to develop additional antioxidative systems.

267 n-black chokeberry (5% w/v) mixture was more antioxidative than the respective controls separately.

268 re randomized in the Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism trial to receive d

269 ction; cardiac defects can be prevented with antioxidative therapy.

270 atory ATPase is a potential novel target for antioxidative therapy.

271 med RNAi and also assessed the phenotype and antioxidative tolerance of the knockdown of TcSOD2 by ex

272 using Nrf2 inducers in chemoprevention, this antioxidative transcription factor may also act as a pro

273 h protein Keap1, a negative regulator of the antioxidative transcription factor Nrf2, binds to CUL3 a

274 ized that FAEs are capable of activating the antioxidative transcription factor nuclear factor (eryth

275 supplement containing glutamine dipeptides, antioxidative vitamins and trace elements, and butyrate