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1 ical axes are oriented either in parallel or antiparallel.
2 el, side-to-side manner, XylR PBP dimers are antiparallel.
3 other and a lower capacitance when spins are antiparallel.
4 ise questions concerning the validity of the antiparallel actin dimer model of in vitro actin polymer
5 monomer concentration is high) cross-linked antiparallel actin dimers are formed in relatively high
7 inated by a pseudo-chain of Pt-Pt dimers and antiparallel alignment of the azide substituents, in com
8 Magnetization switching between parallel and antiparallel alignments of two magnetic layers in magnet
10 stable fusion core structure composed of six antiparallel alpha-helices, and this structure is consid
12 urements, very important differences between antiparallel and parallel ion pair-pi interactions are i
14 amer) and d(GGGTGGGTGGGTGGG) (G3T) fold into antiparallel and parallel quadruplexes, respectively.
15 mbly have been proposed, including parallel, antiparallel, and interlocked antiparallel stacking conf
16 solid state, the hydrogen-bonded dimers are antiparallel, and the beta-strands are fully aligned, wi
17 y limited agreement with either parallel- or antiparallel-arranged dimer structures when spin labels
19 odel to approximate the compact parallel and antiparallel arrangement of alpha-helices and beta-stran
25 rough Eg5, partitioning MTs between a tiled, antiparallel array that promotes spindle expansion and a
26 al G4 unit predominantly coexist in 2-tetrad antiparallel basket and hybrid-2 structures that are arr
27 logical conditions and identify the 2-tetrad antiparallel basket and hybrid-2 topologies as the struc
28 om human telomeres (which we show to form an antiparallel basket structure with a diagonal loop acros
29 nlike fibers, this oligomeric Abeta contains antiparallel beta sheet and binds to a oligomer specific
31 ith a significant fraction of intermolecular antiparallel beta sheet FP structure with adjacent stran
32 e of the homodimer is formed by a 6-stranded antiparallel beta sheet, with every other strand from a
34 her proportion of intermolecular-beta-sheets+antiparallel beta sheets and lower alpha-helix had great
35 beta-sandwich topology formed by 2 sheets of antiparallel beta strands stabilized by the hallmark dis
36 28 shares a "mog1p"-fold consisting of seven antiparallel beta strands stacked between alpha helices.
37 structure shows AtDIR6 as an eight-stranded antiparallel beta-barrel that forms a trimer with spatia
38 ta40 forms an alternative but less populated antiparallel beta-hairpin between the central hydrophobi
43 fied fold comprised of a compact 12-stranded antiparallel beta-sandwich wrapped in two short alpha he
44 dimensional fold contains the three-stranded antiparallel beta-sheet and the disulfide bridge array t
45 eptide demonstrates that the out-of-register antiparallel beta-sheet arrangement of monomers also occ
46 ved for the NTAIL protein that folds into an antiparallel beta-sheet at the A/W interface and present
47 The reason is that NMR data strongly suggest antiparallel beta-sheet calcitonin assembly, whereas mod
48 iophage P22, but TTPA contains an additional antiparallel beta-sheet carrying a lectin-like domain th
50 presence of hydrophobic crowders reduces the antiparallel beta-sheet content of fibrils, whereas hard
51 were dimerized to form a large 10-stranded, antiparallel beta-sheet flanked by alpha-helices on each
52 r to bacterial Psi synthases, with a central antiparallel beta-sheet flanked by helices and loops.
56 orms a novel protein fold of a four-stranded antiparallel beta-sheet stabilized by a crossing-over al
57 peptide chain is sufficient to nucleate some antiparallel beta-sheet structure; addition of beta-capp
58 alpha-helices and a layer of three-stranded antiparallel beta-sheet with flexible N and C termini.
59 ended configuration to form a three-stranded antiparallel beta-sheet with the beta1 and beta2 strands
60 cystatin-like fold composed of a 5-stranded antiparallel beta-sheet wrapped around a 5-turn alpha-he
61 protein structures lead to the formation of antiparallel beta-sheet, beta-turns, intermolecular beta
62 ovel fold organized around a central core of antiparallel beta-sheet, showing an N-terminal alpha/bet
63 intrinsic helicity, while both parallel and antiparallel beta-sheet-like structures are realized.
66 refibrillar oligomers that consist of mainly antiparallel beta-sheets and fibrillar oligomers with on
67 rin complexes require (1) an increase in PF4 antiparallel beta-sheets exceeding approximately 30% (ac
68 n core features a globular architecture with antiparallel beta-sheets forming a central beta sandwich
69 -helical globular protein stabilized by four antiparallel beta-sheets that binds two phosphate moieti
70 fold like architecture which consists of two antiparallel beta-sheets with 7 main strands, packing ag
71 otyrosine vs lysine, coassemble as stacks of antiparallel beta-sheets with precisely patterned charge
72 beta-sheets (recognized by antiserum OC) or antiparallel beta-sheets, beta-solenoids, beta-barrels,
73 housed within a flexible loop connecting two antiparallel beta-sheets, flanked by disordered N- and C
74 uced aggregates consisting preferentially of antiparallel beta-sheets, thus suggesting a modulation e
75 SA2 nanocarriers are built of interdigitated antiparallel beta-sheets, which bear little resemblance
76 All three WW domains display a similar three antiparallel beta-strand structure and interact with the
79 te that formation of hairpins connecting two antiparallel beta-strands determines overall folding.
80 allelic mutations in WDR1 affecting distinct antiparallel beta-strands of Aip1 were identified in all
81 ss a typical Ig-like fold encompassing seven antiparallel beta-strands organized in two beta-sheets,
82 rms a squashed beta-barrel consisting of six antiparallel beta-strands similar to what was observed i
83 n inhibitor cystine knot structure, with two antiparallel beta-strands stabilized by three disulfide
84 ised of two layers of beta-sheets possessing antiparallel beta-strands with each being anchored by a
85 a nine-stranded beta-barrel fold with mostly antiparallel beta-strands, and the loops extending out t
88 regates (1604cm(-1)), H-bonded parallel- and antiparallel-beta-sheets (1690cm(-1)) and H-bonded beta-
89 were positively correlated to intermolecular+antiparallel-beta-sheets and negatively with beta-turn+
91 the Notch1-DLL4 complex reveals a two-site, antiparallel binding orientation assisted by Notch1 O-li
92 also stabilized and rearranged into a novel antiparallel bundle associated with the spindle pole bod
93 spindle bipolarity requires the microtubule antiparallel bundler PRC1/Ase1 to recruit CLASP/Cls1 to
94 ified oMAP4 aligns dynamic microtubules into antiparallel bundles that withstand motor forces in vitr
95 a result, when intersecting microtubules are antiparallel, canonical transport of one microtubule alo
97 lain why nature has evolved the principle of antiparallel chain orientation and has not used the para
100 embrane protein and by combining parallel or antiparallel chloride and proton gradients, we show that
101 urprisingly, this structure is a continuous, antiparallel coiled coil where GCN4-p1 pairs with myosin
106 ysiological solutions have an intramolecular antiparallel configuration that is distinct from the int
107 lix bundles are arranged into an alternating antiparallel configuration, resulting in a much larger 2
109 in fact, the DFNKF sequence is not stable in antiparallel conformation, suggesting that the residue f
111 e frequent interchanges between parallel and antiparallel conformations are thought to occur without
114 sign also provides further evidence that the antiparallel crystal structure provides a good model for
117 magainin 2 derivative displayed a homochiral antiparallel dimer association featuring a "phenylalanin
118 P have provided evidence for formation of an antiparallel dimer at pH 5.5, stabilized by stacking of
124 um binding, the central coiled coil forms an antiparallel dimer, and the C-terminal leucine zipper ap
125 r-transmembrane helix domains folded into an antiparallel dimer, where the orientation of the two dom
129 ngth proceeds from folded monomers to folded antiparallel dimers, tetramers, and hexamers that unfold
131 plex structures: a parallel, a hybrid and an antiparallel DNA and a parallel RNA, in the presence of
132 led angles, and the lines are represented by antiparallel DNA crossover tiles of variable lengths.
133 th conventional double stranded DNA and with antiparallel DNA double crossover molecules, it is clear
134 cation occurs semidiscontinuously due to the antiparallel DNA strands and polarity of enzymatic DNA s
135 when the PNA was targeted to a complementary antiparallel DNA, antiparallel RNA, parallel DNA, and pa
136 ss of bilayer cholesterol concentration, the antiparallel double helix (ADH) conformation was observe
137 we provide a structural perspective on known antiparallel duplex structures in which at least one str
140 on analysis, we found evidence for a similar antiparallel EC1-4 interaction in non-clustered Pcdh fam
143 In sarcomeres, myosin II-mediated sliding of antiparallel F-actin is tightly coupled to myofibril con
146 arized, motile comet tails that associate by antiparallel filament bundling to form bipolar, DNA-segr
149 d a dense and anisotropic array of elongate, antiparallel filaments, whereas myosin II was organized
151 ated to adopt a novel type of mixed parallel/antiparallel fold-back DNA structure, which is stabilize
152 2AG-ThT (50 mM Tris, pH 7.2) solution to the antiparallel form just by the addition of K(+) ions in t
153 yQ fibrils might also be a zipper layer with antiparallel four-stranded stretches as this structure s
154 longer myosin-10 segments in these parallel/antiparallel fusions are dynamic and do not fold coopera
155 ermodynamically stable species (parallel and antiparallel G-quadruplex in K+ and Na+, respectively).
157 is DNA fragment formed a stable two G-tetrad antiparallel G4 with an additional Watson-Crick CG base
159 ive microtubule sliding in both parallel and antiparallel geometries, an activity that has been sugge
160 At 150 mM K(+), POT1 loading unfolds the antiparallel GQ, as the parallel conformation remains fo
162 uence in ssDNA which forms both parallel and antiparallel GQs, dsDNA displays only parallel folding.
163 urn structure in which each monomer forms an antiparallel hairpin and donates two strands to a single
164 proteins dimerize by forming interdigitating antiparallel helical hairpins that position the N-termin
165 discoidal structure, which included pairs of antiparallel helices of apolipoprotein AI circumscribing
167 solution of 2D IR spectroscopy, parallel and antiparallel helix associations were identified by vibra
170 ith those present in the prototypical linear antiparallel heterotetramer as well as recently reported
173 nsmembrane domain and forms a highly unusual antiparallel homodimer that is stably associated with MC
174 eterologous binding partners, BECN1 forms an antiparallel homodimer via its coiled-coil domain (CCD).
176 ork, we sought to design a set of orthogonal antiparallel homodimeric coiled coils using a computatio
179 of three peptides that preferentially formed antiparallel homodimers that, furthermore, did not inter
180 abilizing propeller type loops, shifting the antiparallel htel-22 into hybrid or parallel quadruplexe
181 with oligonucleotides forming mixed parallel/antiparallel hybrid-1 and hybrid-2 topologies {e.g. d[TT
183 the M10:O1 complex displays a chevron-shaped antiparallel Ig-Ig architecture held together by a conse
184 ts that G monomers can re-associate, through antiparallel interactions between fusion domains, into d
185 kinetic constants involving a rapidly formed antiparallel intermediate were observed with oligonucleo
186 ew solid-state NMR constraints that indicate antiparallel intermolecular alignment of beta-strands wi
188 on of push-pull fluorophores originates from antiparallel ion pair-pi attraction to their polarized e
189 he excited state; i.e., parallel rather than antiparallel ion pair-pi interactions are preferred, des
190 l predictions, we find that parallel but not antiparallel ionpair-pi interactions afford operational
191 ization, stability, and motor composition of antiparallel ipMTs at the midzone, thereby facilitating
195 e, involving fusion domains associated in an antiparallel manner to form an intermolecular beta-sheet
198 These activities could promote parallel/antiparallel microtubule organization in meiotic spindle
199 rd the cell's apex and base with a region of antiparallel microtubule overlap at the cell's midzone.
201 the motion of Xklp1 motors on reconstituted antiparallel microtubule overlaps demonstrated that moto
203 e enables them to cross-link and slide apart antiparallel microtubules (MTs) emanating from the oppos
205 ic motor protein, can push apart overlapping antiparallel microtubules to generate a force whose magn
206 fferential is low on parallel and extreme on antiparallel microtubules where one motor domain pair be
207 rallel microtubules at the spindle poles and antiparallel microtubules within the spindle midzone to
212 novel CaM-binding motif, binds to CaM in an antiparallel mode with the N-terminal helix (alpha1) anc
215 ree-helix bundle with 80-residue helices, an antiparallel monomeric right-handed four-helix bundle, a
218 the central beta-hairpin coordinated with an antiparallel motion of the C-terminal helix, which may a
219 used here was to fix the orientation of two antiparallel MRAP molecules and then introduce inactivat
220 vestigated the contribution of the midzonal, antiparallel MT-cross-linking nonmotor MAP, Feo, to this
221 gulator of cytokinesis 1), which cross-links antiparallel MTs and is essential for the completion of
222 associated with MTs may cross-link and slide antiparallel MTs emanating from the two nuclei, whereas
223 preferentially cross-links and slides apart antiparallel MTs while the MT plus ends exhibit dynamic
225 We reveal the solution structure of a short, antiparallel, myosin-10 coiled-coil fused to the paralle
226 short loops two parallel NHR helices and an antiparallel one with the inverse sequence followed by e
227 e parallel configuration with respect to the antiparallel one, while the behaviour of the force patte
228 AtFH14 bundles actin filaments randomly into antiparallel or parallel spindle-like structures; howeve
232 e by in vivo site-specific cross-linking the antiparallel orientation of MreB protofilaments in E. co
233 of E2 assumes a parallel, perpendicular, or antiparallel orientation relative to the membrane's z-di
234 rocess is remarkably efficient, owing to the antiparallel orientation spontaneously adopted by the re
235 B segment, which forms an alpha-helix, in an antiparallel orientation that embodies a variation of th
244 ties in protein aggregation diseases contain antiparallel, out-of-register beta-sheet structures and
247 of links, presumably alpha-actinin, linking antiparallel overlapping ends of the actin filaments fro
251 nts and theoretical calculations point to an antiparallel pi-stacking interaction as the most stable
252 y relationship: The first is the slipped and antiparallel pi-stacking motif which ensures cancellatio
253 in-5 both preferentially cross-link MTs into antiparallel polarity patterns, kinesin-5 cannot substit
255 witch involves the conversion of alternative antiparallel quadruplex structures binding only one cati
256 he CD spectrum of I2 is characteristic of an antiparallel quadruplex that could form as a result of i
257 s primarily remove Gh from Na(+)-coordinated antiparallel quadruplexes but not K(+)-coordinated paral
258 old from a single strand, in which arrays of antiparallel RNA helices are precisely organized by RNA
260 rsions from a parallel DNA/PNA complex to an antiparallel RNA/PNA complex and from a PNA/PNA complex
265 ipole moment, consistent with the contracted antiparallel solid-state pi-pi stacking distances of 8.6
267 he condensation of electrons into pairs with antiparallel spins in a singlet state with an s-wave sym
272 ruplex structures with parallel, hybrid, and antiparallel strand orientations depending on the temper
274 placement at non-H-bonding positions across antiparallel strands has proven useful for achieving ful
276 hanges of telomeric DNA G-quadruplexes to an antiparallel structure (as determined by circular dichro
277 of the human telomeric G-quadruplexes to an antiparallel structure and that this conformational chan
279 parallel arrangement and one of the possible antiparallel structures (with Asp(15) and Phe(19) aligne
280 own to bind preferentially to hybrid than to antiparallel structures, and L2H2-6M(2)OTD, known not to
281 emical basis for F(-) permeation and how the antiparallel subunits convene to form a F(-)-selective p
282 In both crystals, the molecules which are antiparallel (the subPh rings as well as dioxaborine are
284 etization (FDy) has a natural tendency to be antiparallel to Fe(3+) sublattice magnetization (FFe) wi
286 nder the icosahedral 2-fold axis rather than antiparallel to the betaB strand, eliminating many intra
287 etrotransposons for the first time, oriented antiparallel to the coding strand of L1 open reading fra
291 ore of the protease domain undergoes a major antiparallel-to-parallel conformational transition.
292 A first switch is based on a remarkable antiparallel-to-parallel conversion, taking place in a f
298 imicrobial peptides within the unit cell: an antiparallel trimer, which we suggest might be related t
300 angular momentum, aligned either parallel or antiparallel with their linear momentum, labelled as lef
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