ライフサイエンスコーパス: antipode

1 was established by synthesizing its optical antipode.

2 diastereocontrol and allow access to either antipode.

3 ites is higher for the template than for its antipode.

4 ve interactions of both the template and its antipode.

5 m epoxide hydrolase action on the natural JH antipode.

6 ntioselectivity (19 to 50%) for the opposite antipode.

7 he entire egg and converges uniformly on the antipode.

8 to 1.5 pmole as the calcium wave reaches the antipode.

9 h independent pathways leading to both amine antipodes.

10 rophenyl ester (Fmoc-L-Trp(OPfp)), and their antipodes.

11 in magnetization of the lunar crust at their antipodes.

12 he (R)-compound is much more potent than its antipode against the four cancer cell lines examined.

13 nergy sites adsorb both the template and its antipode, although part of them may adsorb only the temp

14 The natural product and its antipode are isolated with >95% ee.

15 Instead, they are antipodes arising from separate enantiomeric biosynthese

16 h only slightly higher affinity than their S-antipodes at the 5-HT(2A) and 5-HT(2C) receptors.

17 , the relative amount of any pair of optical antipodes, constitutes a integral part of the work of an

18 The unnatural antipode (-)-crispine A was similarly prepared in three

19 s(1,4,6)P(3), 4ab], together with the chiral antipodes D-Ins(1,4,6)P(3)(4a) and L-Ins(1,4,6)P(3)(4b),

20 tic evaluation of DPP-IV inhibition by the D-antipode, des-cyano, and amide analogues of NVP-DPP728,

21 Surprisingly, it was found that the D-antipode, despite being approximately 500-fold less pote

22 lly occurring (+)-fomannosin (1) and its (-)-antipode (ent-1) from alpha-D-glucose has been developed

23 The (+)-antipode exhibits interesting biological properties, but

24 sarpagine related indole alkaloids and their antipodes for biological screening.

25 ge opioid receptor ligands with both optical antipodes having high binding affinity.

26 0.93 microM) as the calcium wave reaches the antipode in the fertilized egg.

27 yeast reductases that delivered both alcohol antipodes in optically pure form.

28 dues in DPs affording either the (+)- or (-)-antipodes in the vicinity of the putative binding site a

29 lic NK-1 receptor (Substance-P) antagonist 1 antipode is described.

30 First, crustal disruption at the impact antipode is probably responsible for the observed antipo

31 similar inactivation parameters for the two antipodes, L-alpha-(1'-fluoro)vinyllysine (Ki = 630 +/-

32 hat the domain modeled by peptide III is one antipode of a conformational switch.

33 tiomer of peribysin E from the corresponding antipode of carvone led to a reassignment of the absolut

34 bsequent conjugate addition of the requisite antipode of lithium N-benzyl-N-(alpha-methylbenzyl)amide

35 scribed chemistry, in vitro screening of the antipode of natural dactylolide against the NCI's 60 can

36 synthesized via this method because only one antipode of sparteine is available in nature.

37 Acidic hydration of the unnatural antipode of the [10-(3)H]JHs gives the diol antipode wit

38 convergent, stereocontrolled route to either antipode of the cell adhesion inhibitor, peribysin E, ha

39 e synthesized by this enzyme is the isotopic antipode of the citrate synthesized by the (S)-citrate s

40 To model another antipode of the switch, we introduced two strategic modi

41 Both antipodes of 2-azido-1-arylethanols were synthesized wit

42 heses of the natural (-) and non-natural (+) antipodes of batrachotoxin, as well both enantiomers of

43 This allows ready access to both antipodes of chiral beta-hydroxy nitriles and beta-hydro

44 enantiospecific oxidation peaks toward the R-antipodes of four beta-blocker representatives and addit

45 diastereoselective conjugate addition of the antipodes of lithium N-benzyl-N-(alpha-methylbenzyl)amid

46 ochemical model accounting for the preferred antipodes of the alkanes is proposed and relies on the s

47 Racemization of the optical antipodes of these compounds has been studied using dyna

48 materials and enables access to both optical antipodes of these increasingly useful nucleophilic cata

49 ss to the enantioselective syntheses of both antipodes of those alkaloids can be achieved by kinetic

50 erent enolates (R/S' mixtures), and the same antipodes of two different enolates (R/R' mixtures).

51 of a single enolate (R/S mixtures), opposite antipodes of two different enolates (R/S' mixtures), and

52 rprisingly, the mirror-image isomer (optical antipode) of cyclodal, c[-Arg-d-Phe-d-Lys-d-Dmt-] (2), a

53 negligible activities), whereas the optical antipode proved to be an H4R antagonist ([(35)S]GTPgamma

54 The method was also used to assess the antipode purity of EET standards, and to determine murin

55 ro activity in hemoglobin solutions than its antipode, racemate, and RSR13.

56 The crustal magnetic fields of the Imbrium antipode region are strong enough to deflect the solar w

57 s of conformationally rigid pseudorotational antipodes, revealed that in addition to their different

58 though unique, the synthetic routes to these antipodes share a number of key features, including nove

59 y 20 degrees-wide band which vanishes at the antipode some minutes later.

60 iconal hemiacetal to cyclize the appropriate antipode to optically pure versicolorin B.

61 cyclo[3.1.0]hexane pseudosugar for the north antipode via an intramolecular olefin-ketocarbene cycloa

62 nerated a liganded structure whereby the (S)-antipode was found in the binding pocket.

63 des tested, a general preference for the (S)-antipode was observed, with high ee's for substrates cor

64 The two antipodes were separated via chiral chromatography, and

65 antipode of the [10-(3)H]JHs gives the diol antipode with the same stereochemistry as that from epox