ライフサイエンスコーパス: antiport

1 re opening by lowering the matrix pH (Pi/OH- antiport).

2 feature involved in regulation of Ca(2+)/H+ antiport.

3 r fully protonated malate)/Na(+)-lactate(-1) antiport.

4 es a simultaneous Na(+)/H(+) and malolactate antiport.

5 e impairment in the activity of the Na(+)-H+ antiport.

6 dversely affect the activity of the Na(+)-H+ antiport.

7 of TetA(L) in mediating electrogenic NA+/H+ antiport.

8 ates erythrocyte sugar uniport but not sugar antiport.

9 mono-, di-, and triphosphates by uniport and antiport.

10 two states would result in rapid Na(+)/H(+) antiport.

11 MdtM to catalyse electrogenic bile salt/H(+) antiport.

12 from the thylakoid lumen by proton/potassium antiport.

13 nd transport required for alternating access antiport.

14 rules generally deemed essential for coupled antiport.

15 pointing to electrogenic 3H(+)/propidium(2+) antiport.

16 nsistent with electrogenic 2H(+)/ethidium(+) antiport.

17 lecular movements that underlie CLC-mediated antiport.

18 iport, whereas both AmhT and AmhMT exhibited antiport.

19 es that are responsible for proton/multidrug antiport.

20 ), with the latter being due to a Na(+)/H(+) antiport.

21 h), all of which exhibited Na(+)(Li(+))/H(+) antiport.

22 g on the exact conditions, reversed Na+-Ca2+ antiport.

23 which are inhibitors of the sodium-hydrogen antiport.

24 condary carriers catalyzing substrate/cation antiport.

25 to be facilitated by a putative H+/arginine antiport.

26 fied that inhibits CAX1-mediated Ca(2+)/H(+) antiport.

27 n their concentration gradients, protons are antiported.

28 Electroneutral monovalent cation/proton antiport across the chloroplast envelope has been shown

29 at both yeast and fish CAXs have Ca(2+)/H(+) antiport activities.

30 er that also exhibits monovalent cation/H(+) antiport activity and a net K(+) uptake mode.

31 can essentially ablate this lysosomal Cl-/H+ antiport activity and can strongly diminish the ability

32 aCl-induced increases in V-ATPase and Na+/H+ antiport activity are independent of plant age.

33 strated increased tonoplast-enriched Ca2+/H+ antiport activity as well as increased Ca2+ accumulation

34 onent of the relatively high affinity Na+/H+ antiport activity available to extrude the Na+ and to co

35 H increases beyond the optimum, electrogenic antiport activity ceases, and cytoplasm acidification is

36 runcated VCAX1 had approximately 70% greater antiport activity compared with full-length VCAX1.

37 -borne tetA(L) and related tet(K) genes; the antiport activity conferred by the tet(K) gene had an ap

38 +-translocating ATPase (V-ATPase) and Na+/H+ antiport activity in Mesembryanthemum crystallinum, lead

39 , H(+)-PPase, and (ADP-dependent) H(+)/Na(+) antiport activity in the same compartment.

40 a significant amount of the Na(+),K(+)/H(+) antiport activity in tonoplast vesicles.

41 ize that regulated expression of Ca(2+)/H(+) antiport activity is critical for normal growth and adap

42 Ca(2+)/H(+) antiport activity measured from vacuolar-enriched membra

43 o be an integral membrane protein and has no antiport activity of its own.

44 ode of the electrogenic monovalent cation/H+ antiport activity of TetA(L) and TetK in which K+ takes

45 However, here we show that we can switch the antiport activity of the bacterial Na(+)/H(+) antiporter

46 transformants was detected after the H+/Ca2+-antiport activity was eliminated with bafilomycin A1 and

47 No Orf9-dependent K+(Na+)/H+ antiport activity was found in membrane vesicles.

48 Na+/H+ antiport activity was induced in both juvenile and adult

49 bit a 50% reduction in tonoplast Ca(2+)/H(+) antiport activity, a 40% reduction in tonoplast V-type H

50 vesicles from hum1 mutants lack all Ca2+/H+ antiport activity, demonstrating that Hum1p catalyzes th

51 S1cl7 had greater H(+)-PPiase and Na(+)/H(+) antiport activity, respectively, than the WT.

52 tionally lacks vacuolar membrane Zn(2+)/H(+) antiport activity.

53 logical phenotypes or alterations in Ca2+/H+ antiport activity.

54 chloride/nitrate and a chloride/bicarbonate antiport agent for lipid bilayer transmembrane anion tra

55 very of H+ and HCO3- to Na+/H+ and Cl-/HCO3- antiports, also reduced IOP by 2.9 +/- 0.6 mm Hg.

56 Tet(L)-12 catalyzed Na+/H+ antiport and antiport with K+ as a coupling ion as well

57 of TVP1 and TNHXS1 increased both Na(+)/H(+) antiport and H(+)-PPiase activities and induced the H(+)

58 arply, and recovery required both Na(+)/H(+) antiport and proton current.

59 that LmrP mediates selective calcium/proton antiport and raise interesting questions about the funct

60 s of both transporters catalyze electrogenic antiport and that demonstration of electrogenicity depen

61 Mrp catalyzes secondary Na+/H+ antiport and was hypothesized to have an additional prim

62 al transporters, including reversed Na+-Mg2+ antiport and, depending on the exact conditions, reverse

63 es exhibited a reduction in vacuolar Mn2+/H+ antiport and, like cax1 mutants, reduced V-type H+ -ATPa

64 possibly by both paired Na+/H+ and Cl-/HCO3- antiports and a bumetanide-sensitive Na+-K+-2Cl- symport

65 mediating either calcium or potassium/proton antiport, and facilitating mitochondrial translation.

66 ing K(+)/H(+) (KHA1), Na(+)/H(+)-K(+) (GerN) antiport, and ligand-gated ion channel (KefC).

67 K(m)(app) for 3-O-methylglucose uniport and antiport are unaffected by metabolic poisoning.

68 abbit ciliary epithelium indicating that the antiports are the dominant mechanism.

69 rescent-based assays confirm the Cl(-)/anion antiport as the operational mechanism of the ion transpo

70 Antiport blockade is known to decrease the internal pH o

71 isolated from the mutant showed high H+/Ca2+-antiport but no Ca2+-pump activity.

72 t was consistent with a secondary Na(+)/H(+) antiport, but YqkI-dependent Na(+) uptake depended on in

73 (2+), and Mg(2+) did not support significant antiport by any of the test antiporters.

74 ires VMAT function and results from net H(+) antiport by VMAT out of the vesicle lumen coupled to inw

75 Here a K(+)/H(+) antiport capacity was demonstrated for YhaTU, AmhMT, and

76 6-phosphates is mediated by the P(i)-linked antiport carrier, UhpT, a member of the major facilitato

77 pressing ClC-3 (Ad-ClC-3) induces Cl(-)/H(+) antiport current (I(ClC-3)) in HEK293 cells.

78 ing that it translocates only one proton per antiport cycle.

79 t of a virtual proton from the cytoplasm per antiport cycle.

80 nal domain of 550 residues that precedes the antiport domain appears to tether the full-length AtKEA2

81 lectrogenic and do not result from secondary antiport effects.

82 etailed mechanism of CLC-mediated Cl(-)/H(+) antiport, especially for mammalian isoforms.

83 al/H+ antiport for both proteins; Na+(K+)/H+ antiport for both proteins; and an electrical potential-

84 These include: tetracycline (Tc)-metal/H+ antiport for both proteins; Na+(K+)/H+ antiport for both

85 pal mechanistic elements of proton/substrate antiport have been described, the structural record is l

86 f tetracycline-cobalt/H+, Na+/ H+, and K+/H+ antiport in an assay in which an outwardly directed prot

87 This impaired activity of Na(+)-H+ antiport in CRF was observed in all external concentrati

88 led to catalyze either Tc-metal/H+ or Na+/H+ antiport in energized everted vesicles.

89 Tet(L) but exhibited no tetracycline-Me2+/H+ antiport in Escherichia coli vesicles.

90 d with reduction in the activity of Na(+)-H+ antiport in hepatocytes; (2) this defect is due to the s

91 Standard fluorescence-based assays of Mrp antiport in membrane vesicles from Escherichia coli tran

92 stent with the presence of an active Ca2+/H+ antiport in the thylakoid membrane.

93 ling chambers that coordinate Cl(-) and H(+) antiport in the transporters-are contained wholly within

94 ificantly inhibited KefFC-mediated K(+)/H(+) antiport in vesicles.

95 we examined the possible role of Na(+)/H(+) antiport in Yersinia pestis virulence and found that Y.

96 This study examines the activity of Na(+)-H+ antiport, intracellular pH (pHi), and buffering capacity

97 y unobserved lowering of IOP when the Na+/H+ antiport is also inhibited substantiates a dominant anti

98 bility, that is, proton hopping, hole/proton antiport is identified to account for long-distance char

99 data strongly suggest that intact Na(+)/H(+) antiport is indispensable for the survival of Y. pestis

100 plants, high capacity tonoplast cation/H(+) antiport is mediated in part by a family of cation excha

101 plants, high capacity tonoplast cation/H(+) antiport is mediated in part by a family of CAX (cation

102 best understood model system for Na(+)/H(+) antiport is NhaA from Escherichia coli, for which both e

103 ty of both tetracycline-cobalt/H+ and Na+/H+ antiports is presented.

104 tration, mediated by the V-ATPase and Na+/H+ antiport, is regulated through ABA-independent pathways.

105 trong enough signals for characterization of antiport kinetics.

106 The antiport mechanism accounts for the H(+) uptake involved

107 acilitate the transport of ADP and ATP by an antiport mechanism across the inner mitochondrial membra

108 Selective transport of chloride ions via an antiport mechanism and channel formation in the lipid bi

109 deoxy)nucleoside di- and triphosphates by an antiport mechanism and SLC25A36 cytosine and uracil (deo

110 Uptake activity showed latency, exhibited an antiport mechanism of transport with GMP, and was suscep

111 s a specific transporter that act through an antiport mechanism with PAP as the returning ligand, the

112 ic transporter of PAPS which acts through an antiport mechanism with PAP as the returning ligand.

113 This scenario is distinct from the canonical antiport mechanism, in which both substrate and counteri

114 ollapses the proton motive force by a proton antiport mechanism, in which extracellular protons are e

115 ntrations of PAP supports the function of an antiport mechanism.

116 ective and transports ions via an OH(-)/X(-) antiport mechanism.

117 CPA2 subset may use a channel rather than an antiport mechanism.

118 export substrates using a monovalent cation antiport mechanism.

119 phonium (TPP(+)) out of the cell by a proton antiport mechanism.

120 t is also inhibited substantiates a dominant antiport mechanism.

121 Antiport mechanisms then exchange decarboxylation produc

122 ry exchange (also referred to as uniport and antiport mechanisms, respectively).

123 xport diverse drug substrates, it can couple antiport of a drug to either one or two protons, perform

124 The activity of the Na(+)-H+ antiport of hepatocytes from CRF animals was significant

125 lyaromatic cations due to its proton-coupled antiport of these substrates.

126 the inter- play of different ions (symport, antiport) or by ATP consumption (ATPases).

127 , maintaining stoichiometric proton/chloride antiport over a wide range of proton and chloride concen

128 Of the six possible combinations of antiport partners, Glu(+)/GABA(0) results in proton infl

129 acid-efflux mechanisms, such as the Na(+)-H+ antiport pathway and the Na(+)-independent Cl(-)-HCO3- e

130 present a novel ATP and Na+-dependent Cl-/H+ antiport process that (1) may be directly mediated by th

131 a lesser extent an unusual chloride/sulfate antiport process.

132 n, leads to severe slowing of the Cl(-)/H(+) antiport rate.

133 es of the polar region have little effect on antiport rates.

134 also took up [3H]aspartate in a heterologous antiport reaction that was stimulated or inhibited by an

135 f the physiologically relevant G3P-phosphate antiport reaction were characterized at different temper

136 Despite long-standing dogma that Na(+)/H(+) antiport regulates pH during the phagocyte respiratory b

137 nature of this coupling and the mechanism of antiporting remain topics of debate.

138 dily understood in terms of alternating-site antiport schemes.

139 nt in normoxic avian erythrocytes, but sugar antiport (sugar uptake coupled to sugar exit) is present

140 s mesophyll vacuoles through a specific H(+) antiport system and not by an ion-trap mechanism or ABC

141 higher levels of secondary Na(+)(Li(+))/H(+) antiport than previously reported.

142 We present a free-exchange model for EmrE antiport that is consistent with these results and recap

143 The antiport to uniport switch mechanism requires ATP hydrol

144 ctrical potential (DeltaPsi), Mrp Na(+)/H(+) antiport was shown to be DeltaPsi consuming, from which

145 ysis to explore possible mechanisms for this antiport, we propose that Cl(-)/H(+) exchange involves a

146 in was required for YhaU- and KefC-dependent antiport, whereas both AmhT and AmhMT exhibited antiport

147 lso imply that AmhMT catalyzes NH(4)(+)/H(+) antiport, which would prevent net cytoplasmic H(+) loss

148 Tet(L)-12 catalyzed Na+/H+ antiport and antiport with K+ as a coupling ion as well as or better

149 substrate-loaded transporter, thus enabling antiport without dissipation of the proton gradient.