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1 , in most cases, not associated with a known antisense RNA.
2 e first 14 nucleotides at the 5'-pole of the antisense RNA.
3 production was obtained with the RRE-driven antisense RNA.
4 transcript appears to be an uncharacterized antisense RNA.
5 ent by tetracycline-controlled expression of antisense RNA.
6 quences spliced to exons 4 through 7 of this antisense RNA.
7 cillus subtilis in which the antitoxin is an antisense RNA.
8 d by down-regulation of S1P1 expression with antisense RNA.
9 erence, we silenced expression of ap65 using antisense RNA.
10 lar process regulated by naturally occurring antisense RNA.
11 d by chloramphenical acetyltransferase (CAT) antisense RNA.
12 arget genes, suggesting that RyhB acts as an antisense RNA.
13 ative splicing and promoter utilization, and antisense RNA.
14 ce corresponding to the L region of the EMCV antisense RNA.
15 is by reducing transcription of an imprinted antisense RNA.
16 m can be created through engineering minimal antisense RNAs.
17 viously described and included noncoding and antisense RNAs.
18 ed sRNAs, two are candidate transposase gene antisense RNAs.
19 s such as microRNA, Piwi-interacting RNA and antisense RNAs.
20 MHC genes, and both the intergenic sense and antisense RNAs.
21 ng or ablating Scl using morpholino-modified antisense RNAs.
22 ny new transcripts, including small RNAs and antisense RNAs.
23 n-coding genes, 21,300 pseudogenes, and 1500 antisense RNAs.
24 in-coding transcripts, including 16 possible antisense RNAs.
25 as been their association with noncoding and antisense RNAs.
26 region of complementarity between sense and antisense RNAs.
27 old to over 900-fold, in response to cognate antisense RNAs.
28 RNA 2, cyclin-dependent kinase inhibitor 2B antisense RNA 1 (ANRIL), potassium voltage-gated channel
29 evated levels of hypoxia inducible factor 1A antisense RNA 2 when compared with patients presenting l
30 chain reaction: hypoxia inducible factor 1A antisense RNA 2, cyclin-dependent kinase inhibitor 2B an
32 ease in the p204 level in C2C12 myoblasts by antisense RNA (a) increased the level of the Id2; (b) in
35 conserved; (3) more than 700 distinct small antisense RNAs, about 20 nt long, that are precisely com
37 tion of CgA expression in vivo by expressing antisense RNA against CgA in transgenic mice led to a si
39 or regulated transgene expression generating antisense RNA also reduced the expression of 22-kD zein
40 icrodissection technique coupled with linear antisense RNA amplification and high density/candidate g
41 ns in the hippocampus and entorhinal cortex, antisense RNA amplification was combined with cDNA array
42 es for therapeutic agents such as ribozymes, antisense RNA and antisense oligodeoxyribonucleotides, a
43 hese data provide an unexpected link between antisense RNA and circadian timing and provide a new exa
44 r region drive the overexpression of a novel antisense RNA and contribute to the development of lymph
45 cellular structure of the tau stem loop with antisense RNA and demonstrate that the stability of the
46 progeny of transduced CD34+ cells expressed antisense RNA and exhibited sustained and significant in
48 lease cleavage event that seems to depend on antisense RNA and might implicate endoribonuclease activ
50 se methods (e.g. antisense oligonucleotides, antisense RNA and small interfering RNA) can be used to
51 d by downregulation of their expression with antisense RNA and small interfering RNA, respectively.
52 y, we also observed that the abundance of 52 antisense RNAs and 34 potential noncoding RNAs was affec
53 occurrence and properties of small sense and antisense RNAs and aberrant transcripts in transgenic to
54 on, including inversely regulated modules of antisense RNAs and cognate target messenger RNAs and spe
55 have characterized the association of three antisense RNAs and one intergenically encoded noncoding
56 peutic strategies that target both sense and antisense RNAs and RAN proteins in C9ORF72 ALS/FTD, and
57 s the interaction between the enzyme and the antisense RNA, and the 5'-phosphate stabilizes the inter
59 ate growth inhibitory proteins, peptides and antisense RNAs, and temperature-sensitive mutant protein
60 ical pathways; up-regulation of pseudogenes, antisense RNAs, and unannotated coding isoforms; and RNA
62 tein, whereas inhibiting miR-503 by using an antisense RNA (antagomir) enhanced CUGBP1 biosynthesis a
65 by using small interfering RNA knockdown or antisense RNA approaches in cells in culture resulted in
69 ed with RNA-based agents, such as ribozymes, antisense, RNA aptamers and small interfering RNA, and p
70 ivo, but it is unknown whether the resultant antisense RNAs are a mechanistic by-product of RNA polym
71 RNAseq studies have revealed that bacterial antisense RNAs are abundant, but little is known about t
79 ify a systematic programme in which elevated antisense RNA arising both from ncRNAs and from 3'-overl
83 results indicate that the tightly regulated antisense RNA As1_flv4 establishes a transient threshold
84 romoter for the transcription of a noncoding antisense RNA, asDOG1, that is 5' capped, polyadenylated
86 n of the coenzyme A transferase (CoAT) using antisense RNA (asRNA) against ctfB (the second CoAT gene
88 previously showed that accumulation of PHO84 antisense RNA (asRNA), in cells lacking the nuclear exos
89 h proportion of all eukaryotic genes express antisense RNA (asRNA), which accumulates to varying degr
90 scriptome analyses have revealed hundreds of antisense RNAs (asRNAs) for many bacteria, although few
91 es demonstrated a high number of cis-encoded antisense RNAs (asRNAs) in bacteria, but very little is
92 em from Streptococcus pyogenes and synthetic antisense RNAs (asRNAs) in Escherichia coli strains to r
97 e expression of alternatively polyadenylated antisense RNAs at the locus encoding the floral represso
99 ch to detect hidden similarities between the antisense RNA-binding protein Rop and other proteins.
100 PrgX is believed to act in concert with an antisense RNA called Qa to inhibit readthrough of transc
101 antisense partners and that perturbation of antisense RNA can alter the expression of the sense gene
102 gulation of yhcSR expression by induced yhcS antisense RNA can inhibit and terminate bacterial growth
103 is also described, wherein expression of an antisense RNA confers specific sensitivity to compounds
104 sgenic plants expressing the three different antisense RNA constructs exhibited abnormal growth and d
105 wo of these vectors were designed to express antisense RNA containing either a Rev response element (
108 to regulate the genes encoded opposite them, antisense RNAs could significantly impact gene expressio
109 ells, inhibition of Kalirin expression using antisense RNA decreased nerve growth factor (NGF)-induce
111 ction of a much more abundant class of 22 nt antisense RNAs, dependent on a secondary RdRP (RRF-1) an
112 us type 1 (HIV-1)-based vector expressing an antisense RNA directed against HIV-1 is currently in cli
115 siae, results in transcription initiation of antisense RNAs embedded within body of protein-coding ge
116 esults demonstrate that the robust levels of antisense RNAs emerging from shRNA expression systems ca
120 method to identify a beta-catenin-regulated antisense RNA expressed in HCT116 colorectal carcinoma c
124 Peripheral nerve injury increased Kcna2 antisense RNA expression in injured DRG through activati
127 em, modulation of gene function by inducible antisense RNA expression was demonstrated for comC antis
128 methods, namely RNA interference as well as antisense RNA expression, significantly attenuated serum
129 similarly decreased production of sense and antisense RNA foci, as well as DPR proteins, in patient
132 we identify a conserved lncRNA, named Kcna2 antisense RNA, for a voltage-dependent potassium channel
136 an adhesin, and in addition, we demonstrate antisense RNA gene silencing in T. vaginalis to study th
137 These results suggest a model where small antisense RNAs generated from the 3' end of the transgen
138 merhead ribozyme flanked by two arms of GPRT antisense RNA (GPRZ) was designed, synthesized and found
140 tide substitutions at the 3' terminus of the antisense RNA had no effect on human Ago2 cleavage activ
143 lation of HAS2 mRNA synthesis by the natural antisense RNA HAS2-AS1 has recently been described in os
145 ulation, we observe that cis-encoded natural antisense RNAs have a striking preferential complementar
146 n-coding RNA (lncRNA) HOTAIR (HOX transcript antisense RNA) have diverse functional roles in cancer.
148 that the long non-coding RNA HOX transcript antisense RNA (HOTAIR) is overexpressed in pancreatic ca
149 ion of iASPP by RNA-mediated interference or antisense RNA in C. elegans or human cells, respectively
150 Taken together, our results suggest that antisense RNA in chloroplasts can protect otherwise unst
154 ked out by overexpressing 290-base sense and antisense RNA in NIH 3T3 cells controlled by tetracyclin
155 strand and the relative chance of degrading antisense RNA in the other strand-in the same regions of
162 bryonic stem (ES) cells and demonstrate that antisense RNA induces silencing and deposition of repres
163 ription of the psbN gene, i.e. production of antisense RNA, influences psbT/psbH intergenic processin
164 is-regulatory elements, and we can show that antisense RNAs inhibit PU.1 expression by modulating mRN
166 ncoded negative regulators PrgX and Qa (prgQ antisense) RNA inhibit pCF10 transfer by blocking prgQ t
168 ion by an adenovirus construct encoding p204 antisense RNA inhibited osteoblast-specific gene activat
170 uction of LDHA expression by interference or antisense RNA inhibits tumorigenesis is not well underst
173 Inhibition of p11 expression by inhibitory antisense RNAs (iRNA) treatment resulted in enhanced IFN
174 ranscription of qrf, the long non-coding frq antisense RNA, is induced by light, and its level oscill
176 ession of either dominant-negative allele or antisense RNA knockdown of SecA1 or SecA2 dramatically i
177 restingly, the toxic shRNAs generated higher antisense RNA levels, compared with the nontoxic shRNA.
180 apart, in conjunction with a novel cis-bound antisense RNA linked to Polycomb repressor proteins and
184 s this, we demonstrate how naturally derived antisense RNA-mediated transcriptional regulators can be
185 g three unique features of the plasmid pT181 antisense-RNA-mediated transcription attenuation mechani
186 ating embryonic stem cells, transcription of antisense RNA mediates silencing and methylation of the
189 isense transcripts strengthens the view that antisense RNAs might affect a wider variety of processes
192 all tissue types tested, we detect a pool of antisense RNA of approximately 35 nt, which derives from
196 ne endometrial epithelial cells and that the antisense RNA of Scx (Bop1 intronic RNA) accumulates as
197 ge CTG repeat expansions in the untranslated antisense RNA of the Kelch-like 1 gene (KLHL1), but the
198 hat acts on RNA 2 and replacing them with an antisense RNA oligonucleotide, we have engineered a reco
199 tment of NIH3T3 cells with either caspase-12 antisense RNA or dsRNA corresponding to the full-length
201 These data raise the possibility that this antisense RNA or other RpaR-activated noncoding RNAs med
202 tion of ALDH1A1 in HLECs by ALDH1A1-specific antisense RNA or SiRNA was associated with decreased oxi
203 y, blocking eIF-4E function by expression of antisense RNA, or overexpression of the inhibitory eIF-4
204 mRNA, the primary transcript (pre-mRNA), the antisense RNA overlapping the MHC genes, and both the in
206 Our results provide direct evidence that L1 antisense RNA plays a functional role in chromosome-wide
207 s used as a template for the synthesis of an antisense RNA probe, which is labeled with digoxigenin-l
208 ed by in situ hybridization, by employing an antisense RNA probe; BDNF protein was detected by employ
209 aneous detection of five differently labeled antisense RNA probes and up to seven differ-ent transcri
212 rotocol describes ISH of digoxigenin-labeled antisense RNA probes to whole-mount zebrafish embryos.
213 tional silencing of FLC and reveal roles for antisense RNA processing and DCL3 function in this regul
215 unclear whether this repression requires the antisense RNA product or whether the antisense transcrip
217 studies of the lncRNA HOTAIR (HOX transcript antisense RNA) provide compelling evidence for therapeut
218 e other smaller regulatory RNAs in bacteria, antisense RNAs range in size from tens to thousands of n
220 erococcus faecalis plasmid pAD1 is the first antisense RNA regulated post-segregational killing syste
221 erococcus faecalis plasmid pAD1, is the only antisense RNA regulated postsegregational killing system
222 r rapid degradation, as occurs in most other antisense RNA regulated systems, RNA I and RNA II form a
223 terococcus faecalis plasmid pAD1 is the only antisense RNA-regulated addiction module identified to d
230 nique organization of the par locus, the par antisense RNA, RNA II, binds to its target, RNA I, at re
232 Conversely, inhibition of miR-34a using antisense RNA sensitized lymphoma cells to therapeutic a
233 RNA interference mediated by RNA such as antisense RNA, short interfering RNA and micro RNA is we
234 Addition of functional uPA protein or LRP antisense RNA significantly increased ERK signaling and
235 kinase, antisense oligodeoxynucleotides and antisense RNA, small inhibitory RNA, triple helix, domin
236 ples are presented in which expression of an antisense RNA specifically reduces its cognate mRNA.
237 rotein Hfq promotes the association of small antisense RNAs (sRNAs) with their mRNA targets, but the
239 n PTCs and suggest that transcription of the antisense RNA stabilizes or augments HAS2 mRNA expressio
240 y such host-encoded proteins, we employed an antisense RNA strategy and a lentivirus-based library co
243 egrations driving overexpression of the TERT antisense RNA suggest it may have a role in tumorigenesi
244 ent work on newly identified plasmid-encoded antisense RNAs suggest that there is still much to learn
245 iption site, H3.3 accumulates with sense and antisense RNA, suggesting that it is recruited through a
248 spoIIE and to decrease spoIIE expression via antisense RNA targeted against spoIIE, respectively.
251 identification of a cis-encoded 1.2 kb long antisense RNA - termed AmgR - that is complementary to t
252 We propose that the ratA transcript is an antisense RNA that anneals to the 3' end of the txpA mRN
253 The micF gene encodes a non-translated 93 nt antisense RNA that binds its target ompF mRNA and regula
254 pression of a SMN2 trans-splicing RNA and an antisense RNA that blocks a downstream splice site in SM
256 transcription of a spacer generates a small antisense RNA that is used by RNA-guided Cas nucleases t
257 mids produce plasmid-specific variants of an antisense RNA that regulates conjugation structural gene
258 a-proteobacterial repABC plasmids produce an antisense RNA that regulates the replication initiator i
259 phylococcus aureus plasmid pSK41 produces an antisense RNA that regulates the replication initiator p
260 ermination process requires a 427-nucleotide antisense RNA that spans the intergenic region and acts
261 and H2A.Z show markedly increased levels of antisense RNAs that are normally degraded by the exosome
263 accumulation of rare 26 nt 5'-phosphorylated antisense RNAs that depend on the RdRP homolog RRF-3, th
266 t al that proposes regulating Wilm's tumor-1 antisense RNA to control pathological bone resorption.
269 an isogenic RKO cell line expressing stable antisense RNA to GADD45alpha, a significant protection o
270 A recombinant AAV2 (rAAV2) vector encoding antisense RNA to HIV-1 transactivating region (TAR) was
271 hat mir-21 downregulated, whereas a modified antisense RNA to miR-21 upregulated reporter activity.
272 terminal-repeat-driven constructs expressing antisense RNA to the same target region in HIV-1 but con
273 E-1 interacts with trigger-derived sense and antisense RNAs to initiate RNAi, while several other AGO
274 ited by IC2 (potentially through a noncoding antisense RNA) to the paternal chromosome in a region of
279 e not affected in ALDH3A1-specific SiRNA- or antisense RNA-treated rat lenses, HLECs, or ALDH3A1-null
280 Eliminating cycling of deltaGABA(A)Rs by antisense RNA treatment or gene knockout prevents the lo
281 osome inactivation (XCI) is regulated by the antisense RNA Tsix, which represses Xist on the active X
284 CO-2 transfectants expressing keratin 8 (K8) antisense RNA under a tetracycline-responsive element, w
286 ntext, when a 121-nucleotide segment of atpB antisense RNA was expressed from an ectopic site, an ele
288 genetic tools, along with optimized RBSs and antisense RNA, we engineered B. marmarensis to produce e
289 ng to protein-coding genes, long ncRNAs, and antisense RNAs were due to DNA contamination on the surf
290 g events and an unexpectedly large number of antisense RNAs were identified, revealing new details of
292 yabE is negatively regulated by a cis-acting antisense RNA which, in turn, is regulated by two extrac
294 ates in a complex with transcribed sense and antisense RNA, which is distinct from the DNA/chromatin.
296 by widespread transcription of noncoding and antisense RNAs, which is linked to key chromosomal proce
299 finities and reduced cleavage activities for antisense RNAs with either a 5'-terminal hydroxyl or aba
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