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1 titutively active form of p38 and by an Mdm2-antisense oligodeoxynucleotide.
2 tinuous 7 d intrastriatal infusion of ERK1/2 antisense oligodeoxynucleotide.
3 nd 90% in lungs treated with Smad3 and Smad2 antisense oligodeoxynucleotide.
4 phine with the GR antagonist RU38486 or a GR antisense oligodeoxynucleotide.
5 the erbB-2 receptor was down-regulated using antisense oligodeoxynucleotides.
6 profiles of the same cells transfected with antisense oligodeoxynucleotides.
7 T(1A) antagonists) was not inhibited by G(z) antisense oligodeoxynucleotides.
8 ession than the widely used phosphorothioate antisense oligodeoxynucleotides.
9 ected into Xenopus oocytes with Apx sense or antisense oligodeoxynucleotides.
10 nopus embryos by blocking its synthesis with antisense oligodeoxynucleotides.
11 odified ASOs as compared to first-generation antisense oligodeoxynucleotides.
12 alpha 3, Gs alpha, Gq alpha, and Gx/z alpha antisense oligodeoxynucleotides.
13 ence, we directly targeted neurogranin using antisense oligodeoxynucleotides.
14 suppression of syndecan-4 core protein with antisense oligodeoxynucleotides.
15 eted carriers, bio-adhesive microspheres and antisense oligodeoxynucleotides.
16 subjective day after administration of CalB antisense oligodeoxynucleotides.
17 ly 25% in rats treated with insulin receptor antisense oligodeoxynucleotides.
19 spectively, in cultured embryonic lungs when antisense oligodeoxynucleotide (40 microM) to Smad was a
20 lation of Mos synthesis by microinjection of antisense oligodeoxynucleotides abolished activation of
21 d paws with an 18-mer 3'-3'-end inverted CRF-antisense oligodeoxynucleotide abolishes CWS-induced ant
23 pha bioactivity) or knockdown of TNFRI using antisense oligodeoxynucleotide against TNFRI reduced mec
25 measured while inhibiting CaMKII either with antisense oligodeoxynucleotides against CaMKII or with t
27 dels of vascular proliferative disease using antisense oligodeoxynucleotides against cell cycle genes
28 P2)/CUL-1 complex, we have used the specific antisense oligodeoxynucleotides against either SKP1, SKP
29 en when adult brain mRNA was coinjected with antisense oligodeoxynucleotides against the NR2A subunit
30 e present study examined the actions of four antisense oligodeoxynucleotides aimed at exons 1 (AS1),
31 cyclase (GC) inhibitors, PKG inhibition, or antisense oligodeoxynucleotide (alphaODN) specific for P
32 m mediator of Smad3 and Smad2 proteins, with antisense oligodeoxynucleotide, also resulted in increas
33 reduced by inhibiting Ngb expression with an antisense oligodeoxynucleotide and enhanced by Ngb overe
35 ssing cells was treated with an OVA-specific antisense oligodeoxynucleotide and RNase H, showing that
36 , by dominant-interfering MKK3, and by a p53-antisense oligodeoxynucleotide and was increased by a co
37 apping results facilitated identification of antisense oligodeoxynucleotides and a 10-23 deoxyribozym
38 le inhibitors of the IGF-IR tyrosine kinase, antisense oligodeoxynucleotides and antisense RNA, small
39 bition of PKCmicro synthesis and activity by antisense oligodeoxynucleotides and H-89 (N-(2-[p-bromoc
41 ges of HIPBS and its flanking sequences with antisense oligodeoxynucleotides and RNase H and then by
43 or function, we developed a phosphorothioate antisense oligodeoxynucleotide (AO) to inhibit the expre
44 study examined how selective knock-down (via antisense oligodeoxynucleotides, aODNs) of GABA(A) recep
47 opioid receptor-sensitive feeding, different antisense oligodeoxynucleotide (AS ODN) probes directed
48 nists, and through central administration of antisense oligodeoxynucleotide (AS ODN) probes directed
50 at ex vivo donor allograft transfection with antisense oligodeoxynucleotide (AS ODN) would inhibit th
51 this response, mice were pretreated with an antisense oligodeoxynucleotide (AS-ODN) against neuronal
53 herapy of rabbit autologous vein grafts with antisense oligodeoxynucleotides (AS ODN) blocking cell c
56 sure as a vector for ex vivo transfection of antisense oligodeoxynucleotides (AS-ODN) to intercellula
58 -Dawley rats were treated intravenously with antisense oligodeoxynucleotides (AS-ODNs) directed at AT
59 cts of unilateral microinfusions of GluR2(B) antisense oligodeoxynucleotides (AS-ODNs) into the hippo
60 ect of inhibition of BCR-ABL expression with antisense oligodeoxynucleotides (AS-ODNs) on integrin-me
61 mplicated in some forms of neuropathic pain, antisense oligodeoxynucleotides (AS-ODNs) or mismatch OD
62 n EAAU was explored using neutralizing mAbs, antisense oligodeoxynucleotides (AS-ODNs), and small int
63 pletion of either Galpha(o) or Galpha(q) via antisense oligodeoxynucleotides, as well as by inhibitor
64 resistin levels in mice by use of a specific antisense oligodeoxynucleotide (ASO) directed against re
65 inistration (2 injections over 1 week) of an antisense oligodeoxynucleotide (ASO) directed to reduce
66 characterized the mechanism of action of an antisense oligodeoxynucleotide (ASO) targeting human end
67 ulin resistance, we used a sequence-specific antisense oligodeoxynucleotide (ASO) to lower hepatic Sc
70 ucts of connexin 43 (Cx43) and Cx43-specific antisense oligodeoxynucleotides (asODNs) all act to slow
71 g with pharmacological agents, Cx43-specific antisense oligodeoxynucleotides (asODNs) or dominant neg
72 om P15 atrial myocytes exposed to (1 microM) antisense oligodeoxynucleotides (AsODNs) targeted agains
73 al IK,fast, IK, slow and Iss, the effects of antisense oligodeoxynucleotides (AsODNs) targeted agains
77 hesis that down-regulation of Bcl-2 alone by antisense oligodeoxynucleotides (Bcl-2-AS) induces apopt
80 nsfection of wing and leg cell cultures with antisense oligodeoxynucleotides blocked appearance of ec
81 tificial down-regulation of PKC-epsilon with antisense oligodeoxynucleotides blocked erythropoietin's
82 rc activity associated with gelsolin through antisense oligodeoxynucleotides blocked the stimulation
83 ecreased by 78% after 7 days in culture with antisense oligodeoxynucleotides but was unchanged in tis
86 s, and inclusion of IR beta-subunit-specific antisense oligodeoxynucleotide caused marked dysmorphoge
87 ozygous for Epac1 or mice treated with Epac1 antisense oligodeoxynucleotides, chronic PGE2-induced hy
88 rsal horn after chronic morphine, and a CREB antisense oligodeoxynucleotide coadministered intratheca
92 expression was specifically inhibited by an antisense oligodeoxynucleotide containing two phosphorot
93 MB probes are structured as target-specific antisense oligodeoxynucleotides containing a proximate f
95 he erbB-2 receptor protein by trastuzumab or antisense oligodeoxynucleotides decreased Akt kinase act
96 inhibition of PKG-II but not PKG-Ibeta using antisense oligodeoxynucleotides delayed rhythms of elect
97 fer several advantages over other methods of antisense oligodeoxynucleotide delivery including effici
98 a-neoendorphin analgesia towards the various antisense oligodeoxynucleotides differed markedly from U
100 ays of daily treatment of K562 cells with an antisense oligodeoxynucleotide directed against the init
101 cal animal experiments support the use of an antisense oligodeoxynucleotide directed against the insu
103 namic properties of CGP 69846A/ISIS 5132, an antisense oligodeoxynucleotide directed against the mito
106 tidylinositol 3-kinase inhibitor LY294002 or antisense oligodeoxynucleotides directed against JAK2, E
107 t of several SCCHN cell lines with a pair of antisense oligodeoxynucleotides directed against the tra
108 udies using both neutralizing antibodies and antisense oligodeoxynucleotides directed against these c
111 rs review the early clinical experience with antisense oligodeoxynucleotides, documenting their limit
112 in the presence of TGF-beta type II receptor antisense oligodeoxynucleotides either alone or together
113 which encodes for SUR1 by phosphorothioated antisense oligodeoxynucleotide essentially eliminated ca
114 al myocytes with the PKCalpha and PKCepsilon antisense oligodeoxynucleotides for 5 days significantly
116 ut not reversed by intrathecal injections of antisense oligodeoxynucleotides for the cytoplasmic poly
118 umbar intrathecal administration of specific antisense oligodeoxynucleotides generated against Na(v)1
121 circadian pacemaker and VIP antagonists, and antisense oligodeoxynucleotides have been shown to disru
123 eatment of GN mice with connexin 43-specific antisense oligodeoxynucleotide improved functional and s
124 sents a rational target for modulation using antisense oligodeoxynucleotides in Bcl-2-expressing, EBV
125 d by the D1 antagonist SKF83742 and by a D1A antisense oligodeoxynucleotide, indicating involvement o
129 hypothalamic astrocytes by treatment with an antisense oligodeoxynucleotide inhibited the astrocytic
130 chop in normal murine bone marrow cells with antisense oligodeoxynucleotides inhibited colony-forming
132 , the downregulation of E2F4 expression with antisense oligodeoxynucleotides inhibited NGF-induced ne
133 hermore, intrahippocampal injections of RhoA antisense oligodeoxynucleotides inhibited theta burst st
136 reconsolidation, through infusion of Zif268 antisense oligodeoxynucleotides into the basolateral amy
142 etics, and antitumor activity of the c-raf-1 antisense oligodeoxynucleotide ISIS 5132 (CGP 69846A; IS
143 Cavalpha2delta1 proteins, or Cavalpha2delta1 antisense oligodeoxynucleotides led to a reversal of oro
144 umor cells with appropriate phosphorothioate antisense oligodeoxynucleotides led to specific inhibiti
147 memory consolidation, as their blockade via antisense oligodeoxynucleotide-mediated knockdown leads
148 levels were reduced experimentally, by using antisense oligodeoxynucleotides, mitotic activity in the
149 EphB4 knockdown using specific siRNA and antisense oligodeoxynucleotides molecules led to a profo
150 hase advances in the rat SCN were blocked by antisense oligodeoxynucleotide (ODN) against Per1 and Ca
153 ex to AMPA, in the absence or presence of an antisense oligodeoxynucleotide (ODN) directed against Bc
156 of Na(v)1.8 (PN3/SNS) sodium channels by an antisense oligodeoxynucleotide (ODN) on bladder nocicept
157 clear vitamin D receptor (nVDR) knockout via antisense oligodeoxynucleotide (ODN) prevented the inhib
162 Conversely, embryonic lung culture with an antisense oligodeoxynucleotide (ODN) to the Flk-1 recept
164 eriments, intra-LA infusion of an Arc/Arg3.1 antisense oligodeoxynucleotide (ODN) was observed to be
166 lved in the increase in conductance by using antisense oligodeoxynucleotides (ODN) derived from the a
169 asis on c-ros and c-ret, was investigated by antisense-oligodeoxynucleotide (ODN) gene-targeting stra
173 rimary cerebellar cultures were treated with antisense oligodeoxynucleotides (ODNs) complementary to
174 phagocytosis was examined with two forms of antisense oligodeoxynucleotides (ODNs) designed to hybri
176 ha2C adrenoceptors) were exposed to 5 microM antisense oligodeoxynucleotides (ODNs) for alpha2A and a
177 eption but also for alpha 2 antinociception, antisense oligodeoxynucleotides (ODNs) for the mu-opioid
181 Transient MCAO in rats infused with GLT-1 antisense oligodeoxynucleotides (ODNs) led to increased
182 3-kinase (PI 3-kinase), since inhibitors and antisense oligodeoxynucleotides (ODNs) of Src and PI 3-k
184 tubule cells, two strategies were used: (i) antisense oligodeoxynucleotides (ODNs) to selectively in
186 human papillomavirus type 16 (HPV-16) E6 and antisense oligodeoxynucleotides (ODNs) were used to supp
187 B4 expression by small interference RNA (and antisense oligodeoxynucleotides (ODNs)) led to dose-depe
188 improve intracellular delivery of synthetic antisense oligodeoxynucleotides (ODNs), thereby enhancin
189 l role of the MocuFH1 gene was studied using antisense oligodeoxynucleotides (ODNs), which transientl
190 both neonatal and adult myocytes; the 15-mer antisense oligodeoxynucleotides of each were used for th
192 ate intercellular adhesion molecule (ICAM)-1 antisense oligodeoxynucleotide (oligo) IP-9125 blocks th
193 e (PS) groups to natural phosphodiester (PD) antisense oligodeoxynucleotides (oligo) prevents their i
195 used liposomes to deliver nuclease-resistant antisense oligodeoxynucleotides (oligos) specific for th
198 TSP4 blockade by intrathecal antibodies, antisense oligodeoxynucleotides, or inactivation of the
199 down technologies, such as RNA interference, antisense oligodeoxynucleotides, or ribozymes, are limit
200 ignature induced by the exogenously supplied antisense oligodeoxynucleotide overlaps strikingly with
201 ng explants, while TGF-beta type II receptor antisense oligodeoxynucleotides prevented the downregula
202 Attenuating expression of Na(V)1.8 with antisense oligodeoxynucleotides prevented the redistribu
203 in in the dorsal root ganglion with specific antisense oligodeoxynucleotides prevents hyperalgesia an
208 C3T3-E1 osteoblastic cells treated with P2Y2 antisense oligodeoxynucleotides responded to fluid flow
212 nt with either megalin antibodies or megalin antisense oligodeoxynucleotides resulted in inhibition o
213 ion of xGu in Xenopus laevis oocyte using an antisense oligodeoxynucleotide results in the depletion
215 AT1R mRNA (100 microg/rat, n=9) or scrambled antisense oligodeoxynucleotides (Scr-ODNs, 100 microg/ra
216 protein using EphB4 short interfering RNA or antisense oligodeoxynucleotide significantly inhibits ce
217 on either by high glucose conditions or with antisense oligodeoxynucleotides significantly lowers pro
218 l lines of vascular smooth muscle cells with antisense oligodeoxynucleotide specific to p21(Waf1/Cip1
219 hic receptor binding revealed that D2 and D3 antisense oligodeoxynucleotides specifically and signifi
220 y formation was suppressed by treatment with antisense oligodeoxynucleotides specifically downregulat
224 Overexpression of Bcl-x(L) or treatment with antisense oligodeoxynucleotides targeted against Bax sig
225 re we test the potential of phosphorothioate antisense oligodeoxynucleotides targeted against human C
226 ulating cell cycle progression, we developed antisense oligodeoxynucleotides targeted against PP5 (e.
231 MI-8392 cells with an 18-bp phosphorothioate antisense oligodeoxynucleotide, targeted against the tra
233 onstrate the in vivo antitumor effects of an antisense oligodeoxynucleotide targeting PKC-alpha and s
234 istration of an aerosolized phosphorothioate antisense oligodeoxynucleotide targeting the adenosine A
236 dothelial NO synthase, and 3) application of antisense oligodeoxynucleotides targeting endothelial NO
239 the synthesis of PLP in glial cultures with antisense oligodeoxynucleotides that targeted the PLP in
240 rget mRNA is cleaved, upon treatment with an antisense oligodeoxynucleotide, the 3' cleavage product
241 ls of PAM in HeLa cells were decreased using antisense oligodeoxynucleotides, the basal cAMP content
243 phy (LVH), we inhibited EGFR with a specific antisense oligodeoxynucleotide to attenuate the Ang II-i
245 e effect of intracerebellar microinfusion of antisense oligodeoxynucleotide to Delta(9)-tetrahydrocan
247 in bovine aortic endothelial cells using an antisense oligodeoxynucleotide to G6PD or increased G6PD
248 ter intrathecal injection of a gene-specific antisense oligodeoxynucleotide to knock down the express
249 K562 cells treated for several days with an antisense oligodeoxynucleotide to the initiation codon r
251 solated cerebral arteries treated with TRPM4 antisense oligodeoxynucleotides to downregulate channel
253 f MOR-1 gene expression by administration of antisense oligodeoxynucleotides to hippocampal slices in
256 by chimeric methylphosphonate/phosphodiester antisense oligodeoxynucleotides to just 5% of control le
257 tion of the myeloid cells, and expression of antisense oligodeoxynucleotides to p107 mRNA blocked TGF
262 s, Western blotting, and chemical inhibitors/antisense oligodeoxynucleotides to signaling intermediat
263 HCAECs were incubated in the presence of antisense oligodeoxynucleotides to the 5'-coding sequenc
267 Treatment of AV canal explants with either antisense oligodeoxynucleotides toward Slug or anti-TGFb
271 ta type II receptor immunoperturbation or of antisense oligodeoxynucleotide treatment on lung branchi
275 MDAR subunits NR1, NR2B, NR2D, and NR3A with antisense-oligodeoxynucleotide treatment in the DRG.
276 atenin levels were treated with beta-catenin antisense oligodeoxynucleotides, VEGF-A expression was r
278 rvival, since transfection of Mcl-1-specific antisense oligodeoxynucleotides was sufficient to promot
280 present study, using specific antibodies and antisense oligodeoxynucleotides, we show that this proli
283 lated by up to 53% in culture with 40 microM antisense oligodeoxynucleotide, whereas both scrambled a
284 ptake were inhibited by exogenous LRP or LRP antisense oligodeoxynucleotides, whereas they were incre
287 support the investigation of combinations of antisense oligodeoxynucleotides with cytotoxic chemother
288 acerebroventricular infusion (3-4 d) of G(z) antisense oligodeoxynucleotides, with different sequence
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