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1 (psychotherapy, atypical antipsychotics, and anxiolytics).
2 t is maladaptive, excessive, repetitive, and anxiolytic.
3 activation is positively reinforcing and/or anxiolytic.
4 tect the urocortins, which are thought to be anxiolytic.
5 ng that inhibition of AT1R within the SFO is anxiolytic.
6 beta (ERbeta) agonists have been shown to be anxiolytic.
7 -containing GABAA receptors, was shown to be anxiolytic.
8 opportunities to exploit PTP1B inhibitors as anxiolytics.
9 iety or prescriptions for antidepressants or anxiolytics.
10 r prescription of atypical antipsychotics or anxiolytics.
11 anesthetics, sedatives, anticonvulsants, and anxiolytics.
12 with 3.6 (95% CI, 3.2-4.1) for sedatives and anxiolytics, 2.9 (95% CI, 2.3-3.5) for stimulants, and 2
14 like benzodiazepines, ocinaplon produces an anxiolytic action through allosteric modulation of GABA(
15 h after injury, while it was devoid of clear anxiolytic actions and did not affect water-maze perform
19 tive emotional effects of stress and exerted anxiolytic actions without influencing hypothalamic-pitu
22 to the ventricles exerted antidepressant and anxiolytic activity along with an increase in hippocampa
23 /or alpha3-subtypes may retain the desirable anxiolytic activity of nonselective benzodiazepines but
24 e either striatal and limbic stereotypies or anxiolytic activity, thus outlining their potential to t
26 asingly recognized as an antinociceptive and anxiolytic agent, effects which may be mediated via oxyt
35 evealed that compounds 7a,c,d,l,m,q,r,w show anxiolytic and antiamnestic activities without the unple
37 Cre:gamma2(f/f) mice mimicked the effects of anxiolytic and antidepressant drugs in a number of behav
39 strate in vivo efficacy in rodent models for anxiolytic and antipsychotic activity, respectively.
40 ytocin (OXT) has been revealed as a profound anxiolytic and antistress factor of the brain, besides i
43 levating brain endocannabinoids (eCBs) share anxiolytic and fear extinction-facilitating properties w
44 as generated substantial interest due to its anxiolytic and fear-attenuating effects in rodents, whil
45 hat future work should control carefully for anxiolytic and gender effects, which could underlie inco
47 ABAA receptors do not play a key role in the anxiolytic and muscle-relaxant properties of benzodiazep
48 he possibility of two opposing circuits, one anxiolytic and one anxiogenic, within the BNST, the rela
50 he roots of Valeriana officinalis used as an anxiolytic and sedative and in the treatment of insomnia
51 lly, we directly test the role of FGF2 as an anxiolytic and show that a 3 week treatment regimen of p
56 oid psychotropics, including antidepressants/anxiolytics and sleep aids) in the 90 days postdiagnosis
60 FAAH leads to analgesic, anti-inflammatory, anxiolytic, and antidepressant phenotypes in rodents wit
62 cal inactivation of FAAH produces analgesic, anxiolytic, and antiinflammatory phenotypes but not the
64 D) are nowadays addressed by antidepressant, anxiolytic, and antipsychotic drugs, often administered
65 tility and appetite, and produce anticancer, anxiolytic, and neuroprotective efficacies via cannabino
66 e pharmaceuticals (i.e., antischizophrenics, anxiolytics, and antidepressants) in sludge from 40 repr
67 et of several hallucinogens, antipsychotics, anxiolytics, and antidepressants, and it has been associ
69 c modulators of mGluR5 hold promise as novel anxiolytics, and positive allosteric modulators of mGluR
73 Similarly, voluntary wheel running produces anxiolytic- and antidepressant-like effects in rodent mo
74 R subunit in the amygdala all induced robust anxiolytic- and antidepressant-like effects in several m
75 estradiol pellet, and subsequent protective anxiolytic- and antidepressant-like effects of testoster
76 le for estradiol in mediating the protective anxiolytic- and antidepressant-like effects of testoster
77 ophysiological approaches to investigate the anxiolytic- and antidepressant-like effects of two poten
78 te that Gal(3)-selective antagonists produce anxiolytic- and antidepressant-like effects, possibly by
80 injections or calorie restriction, produced anxiolytic- and antidepressant-like responses in the ele
81 sion and are allosterically modulated by the anxiolytic, anticonvulsant, and sedative-hypnotic benzod
82 sized within the brain and act as endogenous anxiolytic, anticonvulsant, hypnotic, and sedative agent
83 piandrosterone (DHEA) is a neurosteroid with anxiolytic, antidepressant, and antiglucocorticoid prope
84 g neurons may therefore be necessary for its anxiolytic/antidepressant activity and contribute to its
86 with RS67333, similar to fluoxetine, induced anxiolytic/antidepressant-like activity and stimulated a
87 ronic treatment with GR125487 prevented both anxiolytic/antidepressant-like and neurogenic effects of
89 o corticosteroids, opioids, benzodiazepines, anxiolytics, antidepressants, beta-blockers, anaesthetic
90 ed pronounced cannabinoid receptor-dependent anxiolytic, antiinflammatory, and analgesic effects in m
91 task for escape, the elevated plus maze for anxiolytic/anxiogenic effects, place preference conditio
92 clonidine, mexiletine, antidepressants, and anxiolytics as options to treat or modulate pain at vari
95 ng-term object memory recognition, increased anxiolytic behavior, and an increased odor discriminatio
96 erm object memory recognition nor increasing anxiolytic behavior, suggesting state dependency or a de
100 (BNST) inhibitory microcircuit that silences anxiolytic BNST outputs to the ventral tegmental area an
101 function of GABA-A receptors, are effective anxiolytics but carry unwanted side effects including se
102 ncome adults prescribed an antidepressant or anxiolytic by a primary care or non-MH professional and
103 relationship by assessing the effects of the anxiolytic chlorodiazepoxide (CDP; 10 mg/kg) on subjects
105 )R-selective benzodiazepine site agonist and anxiolytic compound TP003 increases tonic currents and d
108 arallel in behaving animals and link them to anxiolytic drug action, novelty, and the metric for self
115 alidity mainly rests on the observation that anxiolytic drugs reduce rodent anxiety-like behavior.
116 uces defense behaviors that are sensitive to anxiolytic drugs, the results of the study suggest that
124 molecular underpinnings of the MitoQ-driven anxiolytic effect and found that MitoQ treatment alters
126 inking effect and exhibited a dose-dependent anxiolytic effect in the rat social interaction model.
129 receptors in the dBNST is necessary for the anxiolytic effect observed following optogenetic stimula
130 d activation of the rACC correlated with the anxiolytic effect of alprazolam (r(p) = .52; p = .04).
133 or and ongoing stress delays or prevents the anxiolytic effect of exercise without affecting exercise
138 ith nonseparated (NS) controls, and that the anxiolytic effect of MS15 would be attenuated in rats in
157 estigations of individual moderators of OT's anxiolytic effects (i.e. sex, genetic factors, and early
159 ed rapid and long-lasting antidepressant and anxiolytic effects and that these effects are associated
162 mice beta-catenin mediates pro-resilient and anxiolytic effects in the nucleus accumbens, a key brain
166 that the acute pharmacological rewarding and anxiolytic effects of alcohol can be measured with fMRI.
173 brafish as a model organism for studying the anxiolytic effects of scopolamine, its mechanisms of act
174 FC completely blocked the antidepressant and anxiolytic effects of systemic ketamine in rodent models
178 In addition, exercise has been shown to have anxiolytic effects, further confounding interpretation o
179 ultiple reports of DHEA's antidepressant and anxiolytic effects, no research to date has examined the
180 spectively, has not produced the anticipated anxiolytic effects, our data show that targeted interfer
181 se CT equivalent has positively reinforcing, anxiolytic effects, suggesting a role in grooming and af
194 ued, promising preclinical data, in terms of anxiolytic efficacy and decreased unwanted effects, have
196 exposure regimen that did not compromise the anxiolytic efficacy of CDP in control mice, the results
197 exposure to the EPM completed abolishes the anxiolytic efficacy of chlordiazepoxide (CDP; 15 mg/kg)
200 d of anxiety patients remain unresponsive to anxiolytics highlighting the need for more effective, me
201 ge, and recent treatment with antipsychotic, anxiolytic/hypnotic, mood stabilizer, and stimulant medi
203 Lef1 is required for the differentiation of anxiolytic hypothalamic neurons in zebrafish and mice, a
204 d the 7-propan-2-olimidazopyrimidine 14k are anxiolytic in both conditioned and unconditioned animal
205 that 4 weeks of voluntary wheel running was anxiolytic in C57BL/6J mice and resulted in a shorter ti
206 Similar to humans, scopolamine acted as an anxiolytic in individual behavioural tests (novel approa
211 n summary, we found that nicotine acts as an anxiolytic in TgR mice but not in control mice and that
214 of 5 mug of DA improved working memory, was anxiolytic in the plus maze, and increased pain sensitiv
217 ce that modulation of alpha5-GABAARs elicits anxiolytic-like actions, whereas our data do not provide
219 a broad antipsychotic-, antidepressant-, and anxiolytic-like activity, not eliciting motor impairment
221 gh affinity value (Ki = 0.27 nM) and for its anxiolytic-like and ability to relieve neuropathic painf
222 GABAA receptor subtype ligands endowed with anxiolytic-like and antihyperalgesic action or enhancer
226 ective agonist, elicited antidepressant- and anxiolytic-like behavioral effects in wild-type mice, wi
227 senger cyclic GMP (cGMP) plays a role in the anxiolytic-like behavioral response of mice to nitrous o
229 pal CA1 region displayed antidepressant- and anxiolytic-like behaviors associated with widespread enh
231 RS 67333 was found to produce a paradoxical anxiolytic-like effect similar to that produced by the 5
232 further characterized and exhibited improved anxiolytic-like effects in a mouse marble burying assay
234 generated behavioral profiles indicative of anxiolytic-like effects in the EZM, which was apparent f
235 al striatum produced antidepressant-like and anxiolytic-like effects on FST and NSFT respectively.
236 D1 receptor antagonist properties might have anxiolytic-like effects that could be useful for treatin
239 ific effects of THC such as memory deficits, anxiolytic-like effects, and social interaction are unde
241 spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms.
243 in the SmartCube behavioral assay and showed anxiolytic-like signatures following daily dose administ
246 s a clinically available, non-benzodiazepine anxiolytic medication that acts on both serotonin and do
247 s a clinically available, non-benzodiazepine anxiolytic medication that acts on serotonin and dopamin
248 nts had increased risk of antidepressant and anxiolytic medication use, while patients with mild AD o
251 Benzodiazepine drugs are highly effective anxiolytic medications, but the role of the benzodiazepi
253 europeptide Y (NPY) is a putative endogenous anxiolytic neurotransmitter that adaptively regulates re
258 neous colitis and, in stressed mice, induced anxiolytic or fear-reducing effects as measured on the e
260 re consistent with the function of NPY as an anxiolytic peptide and help to explain inter-individual
261 orebrain in fb-A2AR KO mice also produced an anxiolytic phenotype in both the elevated plus maze and
263 c hormone, but surprisingly, have a profound anxiolytic phenotype when evaluated using multiple stres
264 GABAergic projections produced rewarding and anxiolytic phenotypes, which were also recapitulated by
268 nociceptin may underlie its anti-alcohol and anxiolytic properties and identify the nociceptin recept
270 E STATEMENT: Neuropeptide Y (NPY) has robust anxiolytic properties, and its levels are reduced in pat
274 dered beneficial to mental health due to its anxiolytic, prosocial and antistress effects, but eviden
276 ynaptic GABAARs could mediate the maintained anxiolytic response to EtOH in dependent individuals, ra
277 nd escitalopram, and median time to onset of anxiolytic response was significantly reduced (P < or =
278 fter a dose of 2.25 g/kg of ethanol: ataxia, anxiolytic response, locomotor activity, core body tempe
280 that THC and other cannabinoids may have an anxiolytic role in central mechanisms of fear behaviors
281 s in modulating anxiety, establish separable anxiolytic roles for different anterodorsal BNST project
282 nds in nonhuman primate models predictive of anxiolytic, sedative, motor, subjective, and reinforcing
285 s a more sensitive measure of the effects of anxiolytics than traditional spatiotemporal indices.
286 AH inhibitors may represent a novel class of anxiolytics that specifically target stress-induced anxi
289 d PTSD and women receiving antidepressant or anxiolytic treatment would be more likely to experience
293 fear vigilance is similar to that seen with anxiolytic treatments in the same cognitive paradigm.
296 ment were treatment naivety, anxiety, use of anxiolytics, use of antidepressants, use of opioids, rib
297 wn to have procognitive, antipsychotic-like, anxiolytic, weight-reducing, glucose-lowering, and wake-
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