ライフサイエンスコーパス: anxious

1 ive stimuli and a propensity to worry and be anxious.

2 ymic, dysthymic, cyclothymic, irritable, and anxious.

3 hallenge (P = 0.007), but children were less anxious.

4 e significantly less calm and happy and more anxious.

5 t down-regulating fears were also less trait-anxious.

6 1 patients (24.0%) as depressed and 40.3% as anxious.

7 - about which they have every right to feel anxious?

8 ed MRI scans were acquired in 151 youths (75 anxious, 76 HV; ages 8-18).

9 Not infrequently, patients are anxious about a scheduled imaging procedure because of a

10 addition, more than 60% of participants were anxious about applying topical corticosteroids to certai

11 acy, did not engage in drunken sex, and were anxious about infection.

12 ly for children whose parents are habitually anxious about math.

13 m scores, especially for students habitually anxious about test taking.

14 n as cardiac, but south Asians would be more anxious about the pain than would Europeans.

15 likely to report feeling "worried, tense, or anxious" about repaying, were 54 percent more likely to

16 d more fear than the healthy groups, but the anxious adolescent and adult groups did not differ on ph

17 During imaging, both anxious adolescents and adults exhibited lower activatio

18 ontal cortex when appraising threat, whereas anxious adolescents exhibited a U-shaped pattern of acti

19 n the ventromedial prefrontal cortex in many anxious adolescents may reflect heightened sensitivity t

20 Anxious adolescents showed greater amygdala activation t

21 anticipated social evaluation leads socially anxious adolescents to misperceive peers as threatening.

22 d with their age-matched counterpart groups, anxious adults exhibited reduced activation in the ventr

23 PD had shorter telomeres than those with no anxious affect (beta: -0.07, P<0.01), but there was no r

24 sorder (PD), as well as depressed affect and anxious affect, were assessed using the Composite Intern

25 Ghr-/- mice are more anxious after acute restraint stress, compared with wild

26 compassion videotape were significantly less anxious after watching it than the women in the other gr

27 Fifty-four anxious alcohol-dependent participants were admitted to

28 Anxious, alcohol-dependent women (age 21-65 years, n=39)

29 substance abuse, prior suicide attempts, and anxious and atypical symptom features.

30 Unlike the anxious and comparison subjects, bipolar disorder youth

31 blation of these dopaminergic neurons led to anxious and depressed behavior, phenocopying performance

32 ysical impairment, pain, fatigue, stiffness, anxious and depressed mood, and lower self-esteem.

33 ore knowledgeable, better informed, and less anxious and depressed patients, with a better mental wel

34 Orexins are altered in anxious and depressed patients.

35 e concerned (medical, work/family), and more anxious and depressed than all other ethnic groups.

36 dult neurogenesis and behavior indicative of anxious and depressive-like mood states.

37 Recovered BN women had an anxious and disorganized behavioral response to m-CPP bu

38 Anxious and healthy adolescents and adults (N=114) compl

39 thors compared prefrontal cortex function in anxious and healthy adolescents and adults following con

40 gdala and vlPFC engagement differentially in anxious and healthy adolescents.

41 Socially anxious and healthy children and adolescents learnt asso

42 on recall, brain activation patterns between anxious and healthy individuals differed.

43 may mediate emotion dysregulation when very anxious and irritable youth process threat-related faces

44 Mice with the enk-/- genotype are more anxious and males display increased offensive aggressive

45 ressant treatment outcomes for patients with anxious and nonanxious major depression in Levels 1 and

46 More anxious and pain-attentive individuals display weaker de

47 safe to perform; however, many patients are anxious and reluctant to undergo serial measurements.

48 their ability to perceive when patients were anxious and stressed than when they were depressed.

49 IBS patients often are anxious and stressed, and stress accelerates small bowel

50 field showed that males were generally more anxious and that stress increased male, but decreased, f

51 on and none of the 13 subjects were severely anxious and/or depressed.

52 use of habit memory that can be produced by anxious and/or stressful emotional states may have impli

53 he the post-MA administration timecourse of 'anxious' and increased ratings of 'bad drug effects,' as

54 rated monkeys displayed heightened avoidant, anxious, and aggressive behaviors, those with hippocampa

55 igmine were significantly less apathetic and anxious, and had fewer delusions and hallucinations whil

56 f self-mutilation tend to be more depressed, anxious, and impulsive, and they also tend to underestim

57 eously make patients more hopeful, confused, anxious, and knowledgeable.

58 aggressive faces when they are feeling more anxious, and this bias leads to increased negative arous

59 s exhibit more dominant behaviours, are less anxious, and, for males only, spend more time in play at

60 ous depression, moderate anxious depression, anxious anhedonia, pure anhedonia, and resolved depressi

61 Together, these findings indicate that anxious animals and those with the greatest EtOH-induced

62 Responses among anxious animals can be confounded further by neophobia t

63 High-anxious animals that are prone to become subordinate dur

64 Low- and high-anxious animals were identified by behavioral responses

65 bability to become dominant observed in high-anxious animals.

66 Entering a state of anxious anticipation triggers widespread changes across

67 hopathology, key neural activity involved in anxious anticipation, and resulting aversive emotional s

68 nization unfolds with time during periods of anxious anticipation.

69 ar-provoking situations but rather increased anxious apprehension and went along with increased anxie

70 sorder distinguishes between acute panic and anxious apprehension as distinct emotional states.

71 While 31.6% of the patients showed strong anxious apprehension during this task (as indexed by inc

72 tients is dynamically organized ranging from anxious apprehension to panic with increasing proximity

73 predominant generalization of fear and hence anxious apprehension.

74 y positively associated with the severity of anxious arousal (ie, hypervigilance) symptoms (r = 0.52)

75 dimensional factors of general distress and anxious arousal as well as a diagnosis of MDD explained

76 ion is associated with increased severity of anxious arousal symptoms in individuals with PTSD.

77 nxiety and depression, and anxiety-specific (anxious arousal) or depression-specific (anhedonia) symp

78 released from the program also appeared more anxious, as indicated by a short latency to vocalize whe

79 ith neuroticism being strongly related to an anxious, avoidant style and affective instability relate

80 to examine the role of endogenous ghrelin in anxious behavior and hypothalamic-pituitary-adrenal axis

81 or anterior orbitofrontal cortex (antOFC) on anxious behavior and Pavlovian conditioned autonomic and

82 Anxious behavior in the mouse is a complex quantitative

83 from MS-induced PVB loss and exhibited less anxious behavior than those infused with control peptide

84 No change in anxious behavior was observed with gap junction blockade

85 e-loxP recombination system, we investigated anxious behavior, spatial memory, and metabolic function

86 l learning/memory and demonstrated increased anxious behavior.

87 anding of network-related aspects underlying anxious behavior.

88 lir in brain areas implicated in fearful and anxious behavior.

89 coustic preferences in mPFC, which mitigates anxious behavior.

90 ggesting that children and adolescents learn anxious behaviors from their parents through a number of

91 tes, while inhibition suppresses, persistent anxious behaviors.

92 emale, Crhr2-deficient mice exhibit enhanced anxious behaviour in several tests of anxiety in contras

93 F2 decreased anxiety-like behavior in highly anxious bLRs without altering other behaviors and withou

94 ring fearful versus happy face processing in anxious, but not healthy, participants.

95 d with each other, namely, patients who were anxious by nature experienced higher levels of state anx

96 Three groups were analyzed: anxious children and adolescents who requested that thei

97 frontal cortex were significantly reduced in anxious children and adolescents who requested that thei

98 Mean activity in these regions in anxious children and adolescents with their caregiver in

99 aregiver accompany them in the scanner room, anxious children and adolescents without their caregiver

100 trategies aimed at reducing the suffering of anxious children and preventing them from developing fur

101 High math-anxious children showed a significant reduction in math

102 ased study found elevated cortisol levels in anxious children susceptible to CO(2)-induced panic, but

103 order, good vocational record, absence of an anxious cluster personality disorder, low neuroticism, a

104 primarily influences the exploratory or the anxious component of responses to approach-avoidance con

105 romes, reaching statistical significance for Anxious/Depressed (0.75 times as high; 95% CI: 0.57, 0.9

106 gression (P<.001); 9%, 14%, 16%, and 27% for anxious/depressed (P<.001); and 7%, 12%, 15%, and 19% fo

107 , was positively associated with symptoms of Anxious/Depressed and Attention Problems (p </= 0.05).

108 ssociations of lead with somatic complaints, anxious/depressed behavior, social problems, attention p

109 ith clinically relevant phenotypes including anxious depression and episodic recurrence.

110 response were compared between patients with anxious depression and those with nonanxious depression.

111 stigated in the clinic for schizophrenia and anxious depression disorders.

112 Similarly, in Level 2, patients with anxious depression fared significantly worse in both the

113 se events, were significantly greater in the anxious depression group.

114 Patients were designated as having anxious depression if their anxiety/somatization factor

115 Anxious depression is associated with poorer acute outco

116 ression: severe anxious depression, moderate anxious depression, anxious anhedonia, pure anhedonia, a

117 res expected of a mouse model of melancholic anxious depression, including reduced survival of adult-

118 nct subtypes of perinatal depression: severe anxious depression, moderate anxious depression, anxious

119 nt in work productivity and higher levels of anxious depression.

120 In Level 1 of STAR*D, 53.2% of patients had anxious depression.

121 rence favoring risperidone was found for the anxious-depression cluster.

122 or depressive disorder (MDD) in general, and anxious-depression in particular, are characterized by p

123 met criteria for melancholic, atypical, and anxious depressive subtypes, as well as subtype combinat

124 these tests in adulthood, reminiscent of the anxious-depressive phenotype previously described for gl

125 nonconflictual interpersonal relationships, anxious-depressive symptoms, substance use, social suppo

126 with high VS-low amygdala reactivity, and by anxious/depressive symptomatology for those with the opp

127 and behavioral changes characteristic of an anxious/depressive-like phenotype.

128 oral changes, which are the expression of an anxious/depressive-like phenotype.

129 as exaggerated among individuals with a more anxious disposition.

130 Depressed mothers with high anxious distress and irritability may require medication

131 of intra-ICU anxiety were significantly more anxious during recovery over 6 months.

132 d, schizotypal, paranoid), and the cluster C anxious, fearful group (obsessional, avoidant) became mo

133 that socially isolated females possessed an anxious, fearful, and vigilant phenotype.

134 Sham rats exhibit a continuum of anxious/fearful behaviors.

135 These anxious feelings can paradoxically co-occur with positiv

136 ith high levels of self-rated depressive and anxious feelings in first grade were more likely to expe

137 e subscale of neuroticism that reflected the anxious form of neuroticism (N1) explained a greater pro

138 During conditioning and extinction, the anxious groups reported more fear than the healthy group

139 oups were matched for age and, among the two anxious groups, for diagnosis (mean age 9.5).

140 ure, whether visceral or vascular, were less anxious, had more understanding, and anticipated less pa

141 alker according to 5 target emotions: angry, anxious, happy, sad, and neutral.

142 The fourth group, anxious high responders (n = 5; 9%), was characterized b

143 ariations in fear responding with clinically anxious humans exhibiting a tendency to generalize learn

144 sorder (ruling out effects merely reflecting anxious hyperarousal), motivating new interventions targ

145 Anxious hypervigilance is marked by sensitized sensory-p

146 function and response regulation as well as anxious-impulsive personality traits may represent endop

147 s and their siblings also exhibited elevated anxious-impulsive personality traits relative to healthy

148 Knockout adults were less anxious in the elevated plus-maze, defecated less, and h

149 at causes retinal degeneration and were less anxious in the maze.

150 pment, but not adult-treated rats, were less anxious in the open field and less immobile in the force

151 recovery and proportion of days depressed or anxious in the preceding year were significantly associa

152 to precisely quantify the process deficit in anxious individuals and determine the degree to which th

153 We show that when the math-anxious individuals are female elementary school teacher

154 Temperamentally anxious individuals can be identified in childhood and a

155 s in healthy individuals, whereas clinically anxious individuals fail to discriminate.

156 h the everyday decision-making of clinically anxious individuals is clearly influenced by their exces

157 Previous studies have shown that anxious individuals may not appropriately differentiate

158 As a result, anxious individuals often make decisions that favor harm

159 Anxious individuals showed persistent, long-term fearful

160 High trait-anxious individuals showed reduced prefrontal activity a

161 that presents in clinical populations where anxious individuals tend to adopt a more pessimistic-lik

162 High math-anxious individuals tend to avoid situations involving m

163 Anxious individuals tend to experience more worry under

164 n analyses provided compelling evidence that anxious individuals' tendency to mis-allocate WM resourc

165 tion is implicated in biased attention among anxious individuals, no work has examined the neural cor

166 om those that generate attentional biases in anxious individuals.

167 g competitors for attention, particularly in anxious individuals.

168 development of a subordinate status in high-anxious individuals.

169 When chronic and extreme, this anxious, inhibited phenotype is an important early-life

170 bsequent uptake was dysregulated in the more anxious Lewis rats.

171 The BAG1 TG mice showed less anxious-like behavior on the elevated plus maze test and

172 Neurally, high-anxious marmosets showed reduced amygdala serotonin leve

173 l as four orthogonal dimensions of symptoms: anxious-misery (mood and anxiety), behavioral disturbanc

174 bstantial empirical intercorrelation between anxious-misery and fear (0.73) suggested that these fact

175 nalizing was modeled as having 2 subfactors (anxious-misery and fear), and a 4-factor model in which

176 en that predispose to disorders dominated by anxious-misery and fear.

177 In contrast, anxious-misery symptoms were associated with widespread

178 erview, which delineated four factors (fear, anxious-misery, psychosis and behavioral symptoms) plus

179 for Anxiety and scores of 2 or higher on its anxious mood and tension factors were eligible.

180 Anxiety (with a score of 2 or higher on the anxious mood and tension items).

181 Depressed mood and anxious mood represent two different quadrants of this s

182 e matter differences in persons featuring an anxious or a nonanxious personality, taking into account

183 When classified by using SAS, 45% were anxious or agitated (SAS 5 to 7), 26% were calm (SAS 4),

184 12 studies), including negative self-esteem, anxious or avoidant behavior, poor emotional knowledge,

185 ic' cognitive bias that is characteristic of anxious or depressed humans and other vertebrates in put

186 cellular DA is high and the generation of an anxious or depressed state when DA is relatively low.

187 dence that the intervention resulted in more anxious or depressive symptoms.

188 sttraumatic stress disorders; social phobia; anxious or melancholic features; or more severe depressi

189 Patients reporting pain were more anxious (OR, 3.53; 95% CI, 1.38-9.03) and depressed (OR,

190 R=5.24, P=0.001), GAD-2 items predicted GAD (anxious: OR=4.09, P=0.003; unable to control worrying: O

191 nd the results will be helpful in reassuring anxious parents.

192 e onset of anxiety disorders in offspring of anxious parents.

193 ence of anxiety disorders among offspring of anxious parents.

194 to healthy control subjects, pathologically anxious participants exhibited enhanced risk aversion bu

195 l) face location, especially in highly trait anxious participants.

196 "Low-anxious" participants showed a reduced amygdala response

197 ded versus attended fearful faces, but "high-anxious" participants showed no such reduction, having a

198 ssfully used to facilitate weaning in a very anxious patient, possibly secondary to anxiolysis or dir

199 from prolonged mechanical ventilation in an anxious patient.

200 cal providers should ask their depressed and anxious patients about the use of alternative medicine.

201 They must manage anxious patients and family members who may be waiting f

202 ok a multicentre, randomised trial on health anxious patients attending cardiac, endocrine, gastroent

203 Anxious patients demonstrated hyperactive prefrontal cor

204 Highly anxious patients reported more pain prior to the procedu

205 The less dentally fearful and anxious patients were in general and the more they trust

206 nxiety disorder diagnosis still tended to be anxious, perfectionistic, and harm avoidant.

207 is typified by a remarkable hypersocial but anxious personality and offers a unique opportunity to i

208 Obsessional, perfectionistic, and anxious personality styles may be premorbid traits that

209 pecific microstructure is associated with an anxious personality, a different structure subserves emo

210 nd OFC, indexing weaker connections in trait-anxious persons.

211 msPs display an anxious phenotype accompanied by elevations in amygdalar

212 cause children and young monkeys express the anxious phenotype in similar ways and have similar neuro

213 at CRH signaling in the amygdala promotes an anxious phenotype that is prevented by FAAH inhibition.

214 ease in the ventral hippocampus correct the "anxious phenotype" caused by early life stress.

215 1A)AR mice exhibited antidepressant and less anxious phenotypes in several behavioral tests compared

216 ework for understanding the pathways linking anxious phenotypes to the development of internalizing p

217 al construction) and behavioral (hypersocial/anxious) phenotypes, offers a unique opportunity to stud

218 entially stressful situation in a clinically anxious population of youths.

219 Childhood behavioral and depressive/anxious problems may influence the risk for PTSD directl

220 rdinate during a social encounter with a low-anxious rat exhibit reduced mitochondrial complex I and

221 d novelty-induced locomotor reactivity, high anxious rats (HA) based on the propensity to avoid open

222 authors tested the hypothesis that elevated anxious reactivity, specifically toward unpredictable av

223 Anxious relative to healthy youths exhibited thicker cor

224 effect was driven to a greater extent by the anxious relative to the depressive characteristics of ne

225 Current measures of anxious responding to threats are limited because they l

226 , objective, within-subject 'stress-test' of anxious responding.

227 se as a non-subjective measure of individual anxious responding.

228 Startle was used to assess anxious responses to cues and contexts.

229 ability to predict aversive events mitigates anxious responses.

230 ith AN displayed increased activation during anxious rumination in the dorsal mid-insula, and activat

231 Participants also performed an anxious rumination task while in the scanner.

232 is, pain, tired, short of breath, restless, anxious, sad, hungry, scared, thirsty, confused).

233 difference in a specific type of depression-anxious somatic depression.

234 t from a difference in a specific subtype of anxious somatic depression.

235 phine dependence and social isolation in non-anxious Sprague Dawley (SD) rats, and a depression model

236 temporal aspects of this transition into an anxious state are poorly understood.

237 l BNST activity promoted several independent anxious state features, whereas anterodorsal BNST-associ

238 Behavioural states in mammals, such as the anxious state, are characterized by several features tha

239 election of features for the assembly of the anxious state.

240 tedly found to exert opposite effects on the anxious state: oval BNST activity promoted several indep

241 ith anxiety self rating, such that the least anxious subjects exhibited the largest BF reductions, wh

242 the largest BF reductions, whereas the most anxious subjects showed no significant BF reduction or a

243 Anxious subjects' exaggerated response to uncertainty le

244 taper success: benzodiazepine dose, level of anxious symptoms at baseline, and duration of benzodiaze

245 lf-reported allergy severity, depressive and anxious symptoms, and attitude toward illness in adolesc

246 (CATIS) as measures of depressive symptoms, anxious symptoms, and attitude toward illness, respectiv

247 ing correlated positively with self-reported anxious symptoms, providing evidence of a continuous cir

248 reported disease severity and depressive and anxious symptoms.

249 ul life events, and offspring depressive and anxious symptoms.

250 By the school year's end, however, the more anxious teachers were about math, the more likely girls

251 ociation between genetic variation in CRHR1, anxious temperament (AT) and brain metabolic activity.

252 Children with an anxious temperament (AT) are at a substantially increase

253 Children with an anxious temperament (AT) are at risk for developing psyc

254 Children with anxious temperament (AT) are particularly sensitive to n

255 When extreme, this anxious temperament (AT) confers elevated risk for the d

256 We established a nonhuman primate model of anxious temperament (AT) for studying the early-life ris

257 Anxious temperament (AT) in human and non-human primates

258 Anxious temperament (AT) is identifiable early in life a

259 d dimensional traits (e.g., neuroticism) and anxious temperament (e.g., behavioral inhibition).

260 Children with an anxious temperament are prone to heightened shyness and

261 es using rhesus monkeys, we characterized an anxious temperament endophenotype that is associated wit

262 learning, which is inversely associated with anxious temperament in mice and humans.

263 Individuals with extreme anxious temperament often show persistent distress in th

264 etween regional brain glucose metabolism and anxious temperament was previously established.

265 We focused on BI, a core component of anxious temperament, because it affords the moment-by-mo

266 a behavioral and neuroendocrine composite of anxious temperament.

267 little is known about the pathophysiology of anxious temperament.

268 avioral and physiological characteristics of anxious temperament.

269 TgR mice behaved as more anxious than controls, an effect normalized by long-term

270 Postpartum rats are less anxious than diestrous virgin females, a phenomenon requ

271 Women with relapsing-remitting MS were more anxious than men with this type (p<0.001), and than wome

272 istological change in the adrenals, are less anxious than mice without SCH.

273 nts receiving personal therapy remained more anxious than patients who received family or supportive

274 ore, alpha(2A)-AR knock-out mice appear more anxious than wild-type C57 Bl/6 mice in the rearing and

275 motor coordination, and were generally more anxious than wild-type controls.

276 ta4-/- mice behaved as though they were less anxious than wild-type littermates on the elevated-plus

277 ale-majority and sex-parity groups felt less anxious than women in female-minority groups.

278 Within twin pairs, the more anxious twin exhibited decreased fractional anisotropy (

279 = 0.022) in the left UF compared to the less anxious twin, controlling for age and gender.

280 res indicated that women were not inherently anxious: usual care group, score of 44.63; relaxation gr

281 ion between amygdala and vlPFC activation in anxious vs healthy adolescents in response to these stim

282 ants reported feeling most positive and most anxious when choosing between similarly high-valued prod

283 gh anxiety sensitivity (AS) become extremely anxious with heart rate increases, palpitations, and sym

284 found that the female LXRbeta(-/-) mice were anxious with impaired behavioral responses but normal lo

285 y behaviorally inhibited and temperamentally anxious young children are at marked risk of developing

286 better response to SSRI and CBT treatment in anxious youth and that neuroimaging may be a useful tool

287 Capitalizing on the ability of anxious youths to manifest low levels of anxiety-like in