ライフサイエンスコーパス: aortae

1 s on pulsatile blood flow through the dorsal aortae.

2 uptake of the tracer in AAA than nondilated aortae.

3 elium-dependent relaxation in isolated mouse aortae.

4 ed specifically for formation of the lateral aortae.

5 tion in the atheroprotected section of mouse aortae.

6 n atherosclerotic lesions of ApoE(-/-) mouse aortae.

7 s, or increase MAPK activation in p47phox-/- aortae.

8 igh levels in LDLR knockout/IL-1ra transgene aortae.

9 on area was found by en face analysis of the aortae.

10 ra was present in C57BL/6J and LDLR knockout aortae, absent in IL-1ra knockout aortae, and present at

11 n microscopy techniques, we examined valves, aortae and coronary arteries from patients with and with

12 Rat aortae and cultured rat aortic endothelial cells were tr

13 ed the vasoactivity elicited by Abeta in rat aortae and in human middle cerebral arteries.

14 In contrast, the dorsal aortae and intersegmental arteries caudal to the heart w

15 e with loss-of-function mutations show small aortae and large cardinal veins.

16 red endothelium-dependent relaxations of rat aortae and led to ER stress in endothelial cells, which

17 gain-of-function Notch alleles show enlarged aortae and underdeveloped cardinal veins, whereas those

18 or its receptor EphB4 also leads to enlarged aortae and underdeveloped cardinal veins; however, endot

19 ions in renal arteries, carotid arteries and aortae, and flow-mediated dilatations in third-order mes

20 expressed in endoderm underlying the lateral aortae, and loss of cxcl12b phenocopies cxcr4a deficienc

21 R knockout aortae, absent in IL-1ra knockout aortae, and present at high levels in LDLR knockout/IL-1

22 Hearts, lungs, aortae, and pulmonary arteries from lipopolysaccharide-t

23 In WT aortae, Ang II increased NADPH-dependent O2- production

24 of two vascular beds are specified, but the aortae are distended and lack contact with the surroundi

25 tly upregulated in the medial layer of db/db aortae, as well as in thoracic aortic samples from patie

26 ling event is the fusion of bilateral dorsal aortae at the midline to form the dorsal aorta.

27 reased poly(ADP-ribosyl)ation of GAPDH in WT aortae, but not in the aortae from PARP-1-deficient mice

28 e also showed dilated thoracic and abdominal aortae compared with control ApoE-/- mice, although athe

29 layer of cells surrounding the paired dorsal aortae concomitant with its expression in the primitive

30 Analysis of smooth muscle cells from mouse aortae demonstrated that MIF deficiency reduced smooth m

31 Dorsal and anterior to the heart, the aortae exhibited abnormally small lumens, as did the ant

32 However, in the fibulin-2 null aortae, fibulin-1 immunostaining was increased in the in

33 kewise, although the primordia of the dorsal aortae formed normally, anomalies were observed in these

34 Aortae from Ang II-infused ApoE-/-OPN-/- mice expressed

35 down-regulation of Hcy metabolic enzymes in aortae from Ang II-infused rats were prevented by BT tre

36 Exposure of thoracic aortae from AT-deficient animals to ox-LDL (0-500 microg

37 Endothelial function was reduced in aortae from Bmal1-KO mice and improved by scavenging rea

38 Aortae from Bmal1-KO mice exhibited enhanced superoxide

39 vity and covalent modification were found in aortae from diabetic animals.

40 on in aortae from wild-type mice, but not in aortae from homozygous null SR-BI knockout mice.

41 on in aortae from wild-type mice, but not in aortae from homozygous null SR-BI knockout mice.

42 ibutes to activation of Vav-1, -2, and -3 in aortae from hyperlipidemic mice and that oxidatively mod

43 ls (BAECs) exposed to HOG-LDL or in isolated aortae from mice fed an atherogenic diet.

44 Aortae from mice were harvested at 4-hour intervals for

45 Aortae from p47phox-/- and matched wild-type (WT) mice (

46 )ation of GAPDH in WT aortae, but not in the aortae from PARP-1-deficient mice.

47 Furthermore, 1-hour in vitro incubation of aortae from streptozotocin-diabetic mice with various PA

48 milarly, vascular smooth muscle cells in the aortae from the LKLF-/- animals displayed a cuboidal mor

49 In aortae from TXNIP-deficient mice, TNF-induced VCAM1 expr

50 endothelium- and NO-dependent relaxation in aortae from wild-type mice, but not in aortae from homoz

51 um- and nitric-oxide-dependent relaxation in aortae from wild-type mice, but not in aortae from homoz

52 Here, we report that dorsal aortae fusion is tightly regulated by a change in signal

53 During aortae fusion, the notochord ceases to exert its negativ

54 human AAA (HAAA) sections compared to normal aortae (HA).

55 s a key factor that shapes the paired dorsal aortae in mouse, as sema3E(-/-) embryos develop an abnor

56 olesterol and surgically transplanting these aortae into recipient Apoe-deficient mice that were trea

57 nd VEGF at the midline, fusion of the dorsal aortae is signaled.

58 VCAM-1 protein expression was increased in aortae obtained from hypercholesterolemic, oophorectomiz

59 ough the original bilaterality of the dorsal aortae occurs as the result of inhibitory factors (antag

60 size and complexity was observed within the aortae of age- and gender-matched apo E-/- and apo E-/-/

61 ects in coverage and association with dorsal aortae of alpha-smooth-muscle-actin-positive cells.

62 [2H]-Cholesterol was retained in aortae of anti-VEGFR3-treated mice.

63 etermined in the ascending and the abdominal aortae of ApoE(-/-) and wild-type mice.

64 Histological analysis of the aortae of ApoE(-/-) and WT mice showed that increased pu

65 vessels from the aortic wall by loading the aortae of donor atherosclerotic Apoe-deficient mice with

66 RNA and protein levels were downregulated in aortae of hypertensive rats.

67 eroprotective cytokine IL-10 were reduced in aortae of IRF5-deficient mice, and in vitro studies demo

68 Aortae of mice treated with Ang II antagonism had fewer

69 erotic plaques, are also up-regulated in the aortae of mice with uPA-overexpressing macrophages, and

70 Endovascular stents were expanded in the aortae of obese insulin-resistant and type 2 diabetic Zu

71 nhanced phospho-Ser536 RelA formation in the aortae of rats chronically infused with Ang II was obser

72 Immunohistochemical staining of the aortae of spontaneously hypertensive rats demonstrated s

73 xide synthase mRNA expression upregulated in aortae of these mice.

74 cent cells was similarly observed in vivo in aortae of young Zucker diabetic rats, compared with lean

75 Exposure of rabbit aortae or ECs to normal flow (12 dyn/cm2, 24 hours) was

76 g by vasculogenesis (particularly the dorsal aortae) or angiogenesis, but low in vessels forming by c

77 Real-time PCR analysis of aortae retrieved from apoE-/- mice demonstrated increase

78 ts in an age-dependent manner, compared with aortae retrieved from C57BL/6 control animals.

79 the groups, whereas en face analysis of the aortae revealed a dose-dependent effect of macrophage LP

80 abeling of organ cultures of embryonic chick aortae revealed rapid formation of disulfide-cross-linke

81 ller fatty streaks in the cusp region of the aortae than did P-selectin-positive mice.

82 Mouse C57BL/6 aortae transduced with adenoviruses containing A20 (or b

83 response were diminished in Egr-1-/-/apoE-/- aortae versus apoE-/-.

84 Rat aortae were banded between the origins of the left renal

85 After 19 weeks on the atherogenic diet, aortae were collected for quantitative analysis of the e

86 Thoracic aortae were excised from anesthetized animals and cut in

87 Rat aortae were isolated 4 days after balloon injury, mainta

88 VSMCs cultured from PRKO mouse aortae were markedly hyperproliferative, and their growt

89 Adult male Sprague-Dawley rats, whose aortae were studied in an in vitro preparation.