ライフサイエンスコーパス: aortic

1 Here, we show that ILC2 are present in para-aortic adipose tissue and lymph nodes and display an inf

2 , correlating abdominal (right and left para-aortic and common iliac) and pelvic (right and left exte

3 (n = 13) fetal sheep were catheterized with aortic and femoral catheters and a flow transducer aroun

4 Aortic and hepatic injuries were more common in patients

5 In ex vivo rings, aortic and mesenteric vessels from SHR treated with DHI

6 egulated tryptophan metabolism and abdominal aortic aneurysm (AAA) is unknown.

7 In the event of rupture of an abdominal aortic aneurysm (AAA), mortality is very high.

8 (HR: 1.78; 95% CI: 1.51 to 2.10), abdominal aortic aneurysm (HR: 1.72; 95% CI: 1.34 to 2.21), and no

9 , including atrial fibrillation (Northwest), aortic aneurysm (Midwest), and endocarditis (Mountain We

10 Sporadic aortic aneurysm and dissections (AADs) are common vascul

11 Prognosis for women with abdominal aortic aneurysm might be worse than the prognosis for me

12 maximal diameter and volume of an abdominal aortic aneurysm sac can be used for temporal monitoring

13 role to atherosclerotic plaque and abdominal aortic aneurysm stability are poorly understood.

14 ) and three who received deferred treatment (aortic aneurysm, pneumonia, and unknown cause); all four

15 r disease causes, the ratio ranged from 1.4 (aortic aneurysm: 3.5 vs 5.1 deaths per 100000 persons) t

16 Abdominal aortic aneurysms (AAAs) are a deadly pathology with stro

17 Abdominal aortic aneurysms (AAAs) represent a potentially life-thr

18 ry of GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions) is a lon

19 itute GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions) Registry

20 human atherosclerotic plaques and abdominal aortic aneurysms and correlated with decreased expressio

21 Heritable thoracic aortic aneurysms and dissections (TAAD), including Marfa

22 with conditions that predispose to thoracic aortic aneurysms and dissections, including MFS.

23 ular inflammation in patients with abdominal aortic aneurysms and predicts the rate of aneurysm growt

24 For centuries, physicians have recognized aortic aneurysms as an acute threat to life.

25 s the development of specific treatments for aortic aneurysms over time and more broadly addresses ho

26 antation for midaortic syndrome and multiple aortic aneurysms, respectively underwent renal transplan

27 a new technique for the repair of abdominal aortic aneurysms.

28 traoperative valve sizing results in smaller aortic annular diameters compared with sizing based on s

29 dex, aortic valve calcification density, and aortic annulus diameter, female sex was an independent r

30 Preoperative MDCT measurements of the aortic annulus served as basis for assignment to a theor

31 (n=7), coarctation of the aorta/hypoplastic aortic arch (n=5), tetralogy of Fallot (n=1), hypoplasti

32 e, Apoe (-/-) Tlr7 (-/-) mice showed reduced aortic arch and sinus lesion areas.

33 Swine aortic arch endothelia exhibited elevated ROS, NOX4, HIF

34 The presence of coarctation shelf and aortic arch hypoplasia were more common in fetuses with

35 eft common carotid artery using an idealized aortic arch model.

36 Selective Aortic Arch Perfusion (SAAP) combines thoracic aortic ba

37 TLR7 deficiency also reduced aortic arch SMC loss and lesion intima and media cell ap

38 e aorta and its large branches, resulting in aortic arch syndrome, blindness, and stroke.

39 or reconstruction of the ascending aorta or aortic arch) with intraoperative bleeding (blood volume

40 selective preservation of embryonic vessels (aortic arches).

41 Abnormal ascending aortic area/height ratio was noted in 33%; 44% underwent

42 A ratio of ascending aortic area/height was calculated on tomography, and >/=

43 rtic Arch Perfusion (SAAP) combines thoracic aortic balloon hemorrhage control with intra-aortic oxyg

44 of early revascularization and use of intra-aortic balloon pump counterpulsation therapy, the progno

45 Compared with intra-aortic balloon pump, Impella provides greater hemodynami

46 and preoperative use of beta-blockers, intra-aortic balloon pump, or catecholamines.

47 ics in myocytes from control rats (SHAM) and aortic-banded rats exhibiting diastolic dysfunction.

48 sities, is drastically reduced following the aortic banding procedure; however the cells are able to

49 es in ionic pathway densities in compensated aortic banding rats maintain Ca(2+) function and efficie

50 and management of structural degeneration of aortic bioprostheses.

51 dy (Assessment of Transcatheter and Surgical Aortic Bioprosthetic Valve Dysfunction With Multimodalit

52 ronary artery calcium (CAC) score, abdominal aortic calcium score, and incident ASCVD (ie, myocardial

53 ession is dramatically altered in Gata2(+/-) aortic cells, which undergo fewer transitions and are re

54 The open aortic cohort comprised 16391 men (71.9%), had a mean (S

55 underwent either sham procedures (n = 8) or aortic constriction (n = 12) with a customized pre-shape

56 eart muscle hypertrophy caused by transverse aortic constriction (TAC) to determine SIRT5's role in c

57 evelopment of heart failure after transverse aortic constriction (TAC) using global and T-cell-specif

58 of nonischemic hypertrophic CHF, transverse aortic constriction (TAC).

59 hypertrophy in mice subjected to transverse aortic constriction and improved cardiac function.

60 rior to any functional decline in transverse aortic constriction hearts.

61 st-specific loss of beta-catenin after trans-aortic constriction in vivo.

62 Moreover, CMs isolated from transverse aortic constriction mice treated with MR-409 showed impr

63 ficient mouse hearts 1 week after transverse aortic constriction showed comparable increases in fibro

64 ensitivity in response to 2 weeks transverse aortic constriction versus sham, linked to enhanced insu

65 re derived from bone marrow after transverse aortic constriction.

66 ardiopulmonary bypass (r=0.30, P=0.007), and aortic cross-clamp times (r=0.32, P=0.004).

67 one third of cases during mapping within the aortic cusps.

68 In conclusion, Small aortic diameter (as opposed to large aortic diameter) is

69 No significant interactions between the aortic diameter and any of the stratified variables were

70 D was found to significantly decrease as the aortic diameter increased according to the tertile of th

71 , Small aortic diameter (as opposed to large aortic diameter) is significantly associated with LE-PAD

72 er increased according to the tertile of the aortic diameter.

73 se 3 gene expression, independent of age and aortic diameter.

74 Ascending aortic dimensions are slightly larger in young competiti

75 Ascending aortic dimensions were significantly larger in a sample

76 Aortic discs isolated from PTP1B siRNA-transfected mice

77 Risk factors for thoracic aortic disease include increased hemodynamic forces on t

78 ntial therapeutic agents to prevent thoracic aortic disease.

79 Thoracic aortic diseases, including aneurysms and dissections of

80 is urgently needed for acute Stanford type A aortic dissection (AAAD) patients due to its high mortal

81 ndovascular aortic repair (TEVAR) for type B aortic dissection (AD).

82 Patients with aortic dissection and active endocarditis were excluded.

83 nitially uncomplicated acute Stanford type-B aortic dissection is associated with a high rate of late

84 Prevalence of previous aortic dissection tended to be higher in males than fema

85 Aortic dissection was suspected clinically, so the patie

86 New cases of endocarditis and aortic dissection were recorded.

87 had type A aortic dissection, 53 had type B aortic dissection, 35 had intramural aortic hematoma, 18

88 y-one patients (13%) had AAS: 125 had type A aortic dissection, 53 had type B aortic dissection, 35 h

89 Aortic dissection, commonly type B, occurs in an appreci

90 ng complications, such as annulus rupture or aortic dissection, remained stable over time, whereas ra

91 ents after an initially uncomplicated type-B aortic dissection.

92 Endocarditis (4.5% versus 2.5%, P=0.037) and aortic dissections (0.5% versus 0%, P<0.001) occurred mo

93 Aortic EC were stimulated with low-dose TNFalpha (0.3 ng

94 mitochondrial respiratory capacity in human aortic ECs.

95 In vitro fibrin clots and rats with aortic EE were treated with an antipseudomonas phage coc

96 at effective concentrations; protects human aortic endothelial cells (HAEC) from cold hypoxia/reoxyg

97 nt of regulatory landscapes of primary human aortic endothelial cells (HAECs) under basal and activat

98 d levels of Kindlin-2 in Kindlin-2(+/-) mice aortic endothelial cells (MAECs) from these mice, and hu

99 We then stimulated primary aortic endothelial cells and ex-vivo atherosclerotic tis

100 ted with reduced ADAMTS7 expression in human aortic endothelial cells and lymphoblastoid cell lines.

101 We treated human aortic endothelial cells with exogenous amphiphiles, sho

102 In human aortic endothelial cells, BA increased beta1-integrin-Ar

103 e MPA may play a major role in limiting full aortic expansion during systole, which modulates left ve

104 [95% CI, -13.5% to 7.9%]) nor between intra-aortic filtration and control (33.3% vs 23.7%; between-g

105 5% CI, -13.8% to 11.2%) and 25.6% with intra-aortic filtration vs 32.4% with control (between-group d

106 d as fatal or nonfatal aortic rupture, rapid aortic growth (>10 mm/y), aneurysm formation (>/=6 cm),

107 type B aortic dissection, 35 had intramural aortic hematoma, 18 had aortic rupture, and 10 had penet

108 Among all subjects, aortic high-level 99mTc-tilmanocept uptake was related t

109 lls and synthetic smooth muscle cells in the aortic intima.

110 iated with spinal cord injury after thoracic aortic ischemia-reperfusion (TAR) in mice.

111 tional class III or IV (p < 0.001), and peak aortic jet velocity (p < 0.001).

112 Abnormal pulsatile aortic loading during exercise occurs in HFpEF independe

113 Abdominal aortic lumen diameters were quantified by ultrasound, wh

114 adenectomy was done in 340 patients and para-aortic lymphadenectomy was done in 196 (58%) of these pa

115 pelvic lymphadenectomy with or without para-aortic lymphadenectomy.

116 Aortic medial amyloid is the most prevalent amyloid foun

117 take of (99m)Tc-RYM1 in vivo correlated with aortic MMP activity and CD68 expression.

118 with evidence of early AKI to receive intra-aortic MSCs (AC607; n=67) or placebo (n=68).

119 was blunted in ECSHIP2(Delta/+) mice, as was aortic nitric oxide bioavailability.

120 aortic balloon hemorrhage control with intra-aortic oxygenated perfusion to achieve return of spontan

121 lmanocept uptake was related to noncalcified aortic plaque volume (r = 0.87; P = .003) on computed to

122 detected carotid, iliofemoral, and abdominal aortic plaques; coronary artery calcification; serum bio

123 stantaneous wave-free ratio, distal pressure/aortic pressure at rest, and FFR were measured in 763 pa

124 ac arrest in this study was defined by intra-aortic pressure monitoring that is not feasible in clini

125 Increased aortic pressure wave pulsatility and greater decrease in

126 onary pressure and flow velocity and central aortic pressure were recorded with sensor wires.

127 Significant reductions in afterload (aortic pressure, P=0.030) and myocardial oxygen demand w

128 operators performing fluoroscopically guided aortic procedures and highlights the protective effect o

129 he study period, patients who underwent open aortic procedures were more likely to be classified as A

130 tic triglyceride content was associated with aortic pulse wave velocity and carotid IMT.

131 differential relationships observed between aortic pulse wave velocity and telomere length in younge

132 nificantly modifies the relationship between aortic pulse wave velocity and telomere length.

133 al artery flow-mediated dilation (FMDBA) and aortic pulse-wave velocity (aPWV) after 4, 8, and 12 wee

134 ontent was associated with an increased mean aortic PWV of 0.19 m/sec (95% CI: 0.03, 0.36) in total a

135 : 0.03, 0.36) in total and an increased mean aortic PWV of 0.42 m/sec (95% CI: 0.03, 0.81) in the abd

136 lacement (TAVR) in patients with pure native aortic regurgitation (AR).

137 s, whereas TAVR had higher rates of residual aortic regurgitation and need for pacemaker implantation

138 tic valve dysfunction, men had more frequent aortic regurgitation than women (33.8% versus 22.2%, P<0

139 ortic stenosis populations, in patients with aortic regurgitation, and in patients with bicuspid aort

140 tenosis, severe mitral regurgitation, severe aortic regurgitation, or subaortic stenosis.

141 valve positioning and reduction of residual aortic regurgitation.

142 Furthermore, aortic relative area change was associated with left ven

143 y via FGFR4, while known effects of FGF23 on aortic relaxation do not require FGFR4.

144 ly guided interventions such as endovascular aortic repair (EVAR) is a growing concern for operators.

145 tween 2008 and 2015 on thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (AD).

146 rarenal, branched, and fenestrated) and open aortic repair using flow cytometry.

147 d for temporal monitoring after endovascular aortic repair, with excellent correlation and interobser

148 ow-up of patients who underwent endovascular aortic repair.

149 ssociated vasoconstriction in an ex vivo rat aortic ring bioassay.

150 A effectively inhibited the sprouts of mouse aortic rings and neoangiogenesis in chick embryo chorioa

151 in expression and function, vascular tone in aortic rings, cholesterol efflux from macrophages, and e

152 6.7%, P<0.001) and diffuse dilatation of the aortic root and ascending aorta (16.2% versus 7.3%, P<0.

153 e atherosclerotic lesions in whole aorta and aortic root area, with markedly increased SRA expression

154 Surgical aortic root enlargement (ARE) during aortic valve replac

155 a, with markedly increased SRA expression in aortic root lesions.

156 surgery, the replacement of multiple valves, aortic root reconstruction, or reconstruction of the asc

157 ially in men and after previous prophylactic aortic root replacement.

158 d (2) incremental prognostic use of indexing aortic root to patient height.

159 n, 35 had intramural aortic hematoma, 18 had aortic rupture, and 10 had penetrating aortic ulcer.

160 rse events were defined as fatal or nonfatal aortic rupture, rapid aortic growth (>10 mm/y), aneurysm

161 eninase than those in adjacent nonaneurysmal aortic sections of human AAA samples.

162 higher numbers of regulatory T cells both in aortic sinus and spleen with higher mRNA expression of C

163 Macrophage numbers in aortic sinuses of CD11d(-/-) mice were reduced without a

164 The ratio of MPA to aortic size correlated with pulse wave velocity (P=0.009

165 In vitro, knockdown of T-cadherin from human aortic smooth muscle cells (HASMCs) with synthetic pheno

166 of contractile markers in co-cultured human aortic smooth muscle cells (HASMCs).

167 r defects due to this ACTA2 mutation in both aortic smooth muscle cells and adventitial fibroblasts m

168 ewire and advancing it into a pre-positioned aortic snare.

169 001), whereas women were more likely to have aortic stenosis (34.5% versus 44.1%, P<0.001).

170 70 patients with BAV undergoing surgery for aortic stenosis (aorta diameter </=45 mm: BAVnon-dil or

171 rdiovascular risk factors and development of aortic stenosis (AS).

172 isturbed flow as it occurs, for instance, in aortic stenosis (AS).

173 Low-gradient severe aortic stenosis (LGSAS) with preserved ejection fraction

174 al mechanical intervention for patients with aortic stenosis and concomitant reduced ejection fractio

175 Patients with severe, symptomatic aortic stenosis and high/intermediate surgical risk were

176 , 2016, 203 patients with severe symptomatic aortic stenosis and increased surgical risk, as determin

177 For patients with asymptomatic severe aortic stenosis and normal left ventricular function, cu

178 Depending of the severity of the aortic stenosis and the presence of concomitant heart di

179 (TAVR) for patients with severe symptomatic aortic stenosis at intermediate surgical risk, TAVR volu

180 ternative to surgery in patients with severe aortic stenosis at intermediate surgical risk, with a di

181 l-accepted option for treating patients with aortic stenosis at intermediate to high or prohibitive s

182 surgical aortic valve replacement for severe aortic stenosis between 2012 and 2014 at our institution

183 alve replacement (TAVR) for the treatment of aortic stenosis in high- and intermediate-risk patients,

184 Studies of TAVR in low-flow severe aortic stenosis patients have demonstrated that TAVR has

185 investigating the role of TAVR in lower-risk aortic stenosis populations, in patients with aortic reg

186 d treatment of patients with low-flow severe aortic stenosis remains challenging.

187 rance status, left ventricular function, and aortic stenosis severity between patients with (n = 202)

188 is standard therapy for patients with severe aortic stenosis who are at high surgical risk.

189 ibes the epidemiology and pathophysiology of aortic stenosis with heart failure and reduced ejection

190 patients with known bicuspid valve, moderate aortic stenosis, severe mitral regurgitation, severe aor

191 relief of valve obstruction in patients with aortic stenosis, there is an independent association bet

192 utcomes in patients with asymptomatic severe aortic stenosis.

193 sk, and many intermediate-risk patients with aortic stenosis.

194 and PAD risk factors overlap with those for aortic stenosis.

195 E/A), myocardial performance index (MPI) and aortic stiffness (pulse wave velocity; PWV) were evaluat

196 Assessment of aortic stiffness was evaluated by measuring pulse wave v

197 H patients have increased apparent ascending aortic stiffness, which was strongly associated with the

198 controls, respectively; P=0.001) and reduced aortic strain (23% versus 29%; P<0.0001) and distensibil

199 d with pulse wave velocity (P=0.04) and with aortic strain (P=0.02).

200 evaluated by measuring pulse wave velocity, aortic strain, and distensibility.

201 the study, 22836 (25.3%) had undergone open aortic surgery and 67467 (74.7%) had had infrainguinal b

202 io was noted in 33%; 44% underwent ascending aortic surgery at 34 days.

203 Aortic tissue from Micu2(-/-) mice had increased express

204 Aortic tissue MMP activity and macrophage marker CD68 ex

205 of all patients enrolled in the Placement of Aortic Transcatheter Valves (PARTNER) 1 Trial with succe

206 (The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves [PARTNER II]; NCT01314313).

207 as an essential mechanism that specifies the aortic tree, and provide a new framework for how mutatio

208 a halfway between the right renal artery and aortic trifurcation into the iliac and tail arteries.

209 8 had aortic rupture, and 10 had penetrating aortic ulcer.

210 Finally, aortic uptake of (99m)Tc-RYM1 in vivo correlated with ao

211 High-intensity aortic valve (18)F-fluoride uptake was observed in all p

212 RATIONALE: The pathogenesis of bicuspid aortic valve (BAV)-associated aortopathy is poorly under

213 ricular septal defect (P=0.12), and bicuspid aortic valve (P=0.14) did not carry an increased risk fo

214 In patients with bicuspid aortic valve and dilated proximal ascending aorta, we so

215 for major complications involving the aorta, aortic valve annulus, and left ventricle.

216 Severe PAS was defined as aortic valve area <0.8 cm(2), mean aortic valve gradient

217 ghty-seven consecutive patients with reduced aortic valve area and normal stroke volume index undergo

218 Aortic valve area increased to >/=1.0 cm(2) in 6 LF (24%

219 tients with moderate-severe asymptomatic AS (aortic valve area, 0.5+/-0.1 cm(2)/m(2); peak gradient,

220 The duration of the aortic valve artifact was 39+/-8 ms with amplitude of 0.

221 Aortic valve artifact was observed while mapping within

222 (Registry of Aortic Valve Bioprostheses Established by Catheter [FRAN

223 Median aortic valve calcification (1973 [1124-3490] Agatston un

224 Aortic valve calcification density correlated better wit

225 After adjustment for age, body mass index, aortic valve calcification density, and aortic annulus d

226 emature ventricular contraction ablation, an aortic valve closure artifact is observed in up to one t

227 In calcific aortic valve disease (CAVD), activated T lymphocytes loc

228 RATIONALE: Aortic valve disease is a cell-mediated process without

229 is in mice causes accelerated progression of aortic valve disease.

230 utic candidates targeting the progression of aortic valve disease.

231 regurgitation, and in patients with bicuspid aortic valve disease.

232 in the context of both moderate and advanced aortic valve disease.

233 chanical haemodynamic consequences of severe aortic valve diseases (with preserved LV ejection fracti

234 KEY POINTS: Severe aortic valve diseases are common cardiac abnormalities t

235 nto the haemodynamic cardiac consequences of aortic valve diseases in those with preserved LV ejectio

236 When presenting with moderate/severe aortic valve dysfunction, men had more frequent aortic r

237 n high-risk patients, TAVR for bioprosthetic aortic valve failure is associated with relatively low m

238 We, thus, aimed to assess sex differences in aortic valve fibrocalcific remodeling.

239 Aortic valve function was divided into normal, regurgita

240 ongenital bicuspid aortic valves, with worse aortic valve function, fibrosis, and calcification than

241 efined as aortic valve area <0.8 cm(2), mean aortic valve gradient >/=40 mm Hg, and dimensionless ind

242 ients of more than 20 mm Hg and increases in aortic valve gradients of more than 10 mm Hg (12 [14%] o

243 ents with subclinical leaflet thrombosis had aortic valve gradients of more than 20 mm Hg and increas

244 post-TAVR, with a decrease of -2.9 mm Hg in aortic valve mean gradient, an increase of 0.028 in Dopp

245 that M2FA is present in plaque found on the aortic valve of ApoE (-/-) mice.

246 Furthermore, metoprolol reduced aortic valve peak -7 mm Hg (-13, 0; P=0.05) and mean -4

247 eglects the velocity distribution across the aortic valve plane.

248 urgical aortic root enlargement (ARE) during aortic valve replacement (AVR) allows for larger prosthe

249 With the approval of transcatheter aortic valve replacement (TAVR) for patients with severe

250 ized trials support the use of transcatheter aortic valve replacement (TAVR) for the treatment of aor

251 Transcatheter aortic valve replacement (TAVR) has become a well-accept

252 ata evaluating the outcomes of transcatheter aortic valve replacement (TAVR) in diabetic patients are

253 t about safety and efficacy of transcatheter aortic valve replacement (TAVR) in patients with pure na

254 Transcatheter aortic valve replacement (TAVR) is standard therapy for

255 urological complications after transcatheter aortic valve replacement (TAVR) may be reduced with tran

256 scious sedation is used during transcatheter aortic valve replacement (TAVR) with limited evidence as

257 Early experience with transcatheter aortic valve replacement (TAVR) within failed bioprosthe

258 (Cerebral Protection in Transcatheter Aortic Valve Replacement [SENTINEL]; NCT02214277).

259 ies are a common finding after transcatheter aortic valve replacement and often result in permanent p

260 42 189 patients who underwent transcatheter aortic valve replacement between the years 2011 and 2014

261 eatment distribution including transcatheter aortic valve replacement eligibility in low-risk patient

262 eValve, Evolut R, and SAPIEN 3 transcatheter aortic valve replacement enrolled in the RESOLVE study (

263 ely analyzed 78 patients undergoing surgical aortic valve replacement for severe aortic stenosis betw

264 Transcatheter aortic valve replacement has become the procedure of cho

265 In recent years, use of transcatheter aortic valve replacement has expanded to include patient

266 which could postpone or prevent the need for aortic valve replacement in patients with asymptomatic A

267 Surgical aortic valve replacement in patients with small annular

268 onsecutive patients undergoing transcatheter aortic valve replacement in Switzerland between February

269 Transcatheter aortic valve replacement might be a good alternative; ho

270 However, the transcatheter aortic valve replacement patient presents a unique chall

271 size and (2) to a theoretical transcatheter aortic valve replacement valve size.

272 New generation devices for transfemoral aortic valve replacement were optimized on valve positio

273 Transfemoral aortic valve replacement with the ES3 and the Lotus were

274 After aortic valve replacement, left ventricular afterload is

275 atients who may have undergone transcatheter aortic valve replacement, we conducted a subgroup analys

276 oor, and current guidelines recommend prompt aortic valve replacement.

277 r computed tomography within 3 months before aortic valve replacement.

278 tcome in patients eligible for transcatheter aortic valve replacement.

279 jection fraction recovery post-transcatheter aortic valve replacement.

280 Appropriate valve sizing is critical in aortic valve replacement.

281 w-up measurements were performed in HOCM and aortic valve stenosis patients 4 months after surgery.

282 tive cardiomyopathy (HOCM), 10 patients with aortic valve stenosis, and 14 healthy individuals using

283 In contrast to patients with aortic valve stenosis, MEE was not improved in patients

284 ase involving premature calcification of the aortic valve, a phenotype that closely mimics human dise

285 ed cohorts of patients who underwent primary aortic-valve replacement or mitral-valve replacement wit

286 Among patients who underwent aortic-valve replacement, receipt of a biologic prosthes

287 (TAVR) within failed bioprosthetic surgical aortic valves has shown that valve-in-valve (VIV) TAVR i

288 than those Npr2(+/-) with typical tricuspid aortic valves or all wild-type littermate controls.

289 Additionally, 4 patients with mechanical aortic valves, who underwent scar-related ventricular ta

290 eterozygous for Npr2 had congenital bicuspid aortic valves, with worse aortic valve function, fibrosi

291 timing of the observed artifacts with native aortic valves.

292 e leg raise was performed and an increase of aortic velocity time integral greater than or equal to 1

293 ent =0.931; P<0.001) over both iterative and aortic velocity-time integral methods.

294 ruitment of CD36(+)(high) macrophages to the aortic wall and trigger atherogenesis.

295 RATIONALE: The thoracic aortic wall can degenerate over time with catastrophic c

296 is a novel approach to the identification of aortic wall cellular inflammation in patients with abdom

297 n Il27ra (-/-) APC and CD4(+) T cells in the aortic wall contribute to T cells re-activation and pro-

298 f view through the entire depth of an intact aortic wall.

299 Central aortic waveform analysis may enable better individualiza

300 f the upper border of the symphysis pubis to aortic zone I (descending thoracic aorta) and zone III (