ライフサイエンスコーパス: apical dendrite

1 perpolarizing injections in the soma or main apical dendrite.

2 of the recording probe with the axis of the apical dendrite.

3 topped close to the junction of the soma and apical dendrite.

4 e of these neurons is the axon origin at the apical dendrite.

5 educed dendritic complexity and thinner main apical dendrite.

6 Ca2+ spike (LTS) throughout the granule cell apical dendrite.

7 these neurons comes from studies of the main apical dendrite.

8 f action potentials backpropagating into the apical dendrite.

9 one of which supported Ca(2+) spikes in the apical dendrite.

10 al cells with paler cytoplasm, often with an apical dendrite.

11 esting [Ca(2+)] was 32-59 nM in the proximal apical dendrite.

12 ansformation of the leading process into the apical dendrite.

13 rly from the soma, and leveled at the distal apical dendrite.

14 ated K(+) channel was uniform throughout the apical dendrite.

15 granule cells (DGCs) have a single, complex, apical dendrite.

16 te, which differ mainly on the extent of the apical dendrite.

17 ominantly within their soma, rather than the apical dendrite.

18 g translocation of the soma into an existing apical dendrite.

19 d this horizontal spread was due to off-axis apical dendrites.

20 feliforms) exhibiting bifurcating, V-shaped apical dendrites.

21 of these pyramidal neurons or along layer 5 apical dendrites.

22 k and strong inputs were both located in the apical dendrites.

23 targeted progressively higher regions of the apical dendrites.

24 nitiates degenerative signaling generally in apical dendrites.

25 and highly reliable property of neocortical apical dendrites.

26 ls mediating this current are located in the apical dendrites.

27 cal in the soma and the first 300 mum of the apical dendrites.

28 ns of DA can be attributed to effects in the apical dendrites.

29 vident age-related differences in LTP in the apical dendrites.

30 ersus young adult slices and in basal versus apical dendrites.

31 of Schaffer-collateral synapses in the upper apical dendrites.

32 s in the series, durably inhibits the distal apical dendrites.

33 and shifted their initiation site along the apical dendrites.

34 bition rapidly shifts from their soma to the apical dendrites.

35 perisomatic membrane of PNs, and not on the apical dendrites.

36 K(+) current uniformly distributed along the apical dendrites.

37 ex and developed misoriented, often inverted apical dendrites.

38 larization observed at the tips of basal and apical dendrites.

39 ns) elicited by stimulations of the soma and apical dendrites.

40 controlling electrogenesis in pyramidal cell apical dendrites.

41 emonstrating coincidence detection along the apical dendrites.

42 ned within the region circumscribed by their apical dendrites.

43 that often displayed infoldings and thicker apical dendrites.

44 nd superficial cells short or absent primary apical dendrites.

45 rs and structural abnormalities of subicular apical dendrites.

46 tory synaptic contacts with the proximal CA3 apical dendrites.

47 l pyramidal neurons receive input onto their apical dendrites.

48 more concentrated in basal dendrites than in apical dendrites.

49 cells of the frontoparietal cortex and their apical dendrites.

50 classes for axons, dendrites, and pyramidal apical dendrites.

51 by the thick elongate shape of their primary apical dendrites.

52 s PNs primarily innervate basal and proximal apical dendrites.

53 ing the number of inhibitory synapses on the apical dendrites.

54 kinetics as they undergo strong filtering by apical dendrites.

55 eral and temporoammonic inputs at the distal apical dendrites.

56 (2)(+) influx and regenerative potentials in apical dendrites.

57 d strong PIST-labeling, extending into their apical dendrites.

58 the soma and proximal portion of tufted cell apical dendrites.

59 lucifer yellow to visualize their basal and apical dendrites.

60 dendrite formation in vivo without affecting apical dendrites.

61 mice show a pronounced shift toward shorter apical dendrites.

62 reduced, as was electrical coupling between apical dendrites.

63 voked a localized Ca(2+) wave in the primary apical dendrites.

64 ic lengths and field sizes, and identifiable apical dendrites.

65 tenin expression shifts primarily to nascent apical dendrites, a pattern that continues through adult

66 tion potentials was greatest in the proximal apical dendrite and declined steeply with increasing dis

67 eurons appear pyramidal, growing a prominent apical dendrite and few small basal dendrites.

68 proximal, middle, and distal segments of the apical dendrite and measured boosting of subthreshold an

69 ap junctions distributed uniformly along the apical dendrite and, on average, proximally with respect

70 es with heads increases by 162% on secondary apical dendrites and 113% on basal dendrites.

71 without heads) increases by 38% on secondary apical dendrites and 88% on basal dendrites and the numb

72 romast zones additionally showed labeling of apical dendrites and commissural cells, but the ampullar

73 found to have constitutive atrophy of distal apical dendrites and decrements in apically targeted exc

74 Axons of these bipolar cells arise from the apical dendrites and follow a course through the optic t

75 ted predominantly in CA2/CA3a pyramidal cell apical dendrites and in interneurons in CA1-3 stratum or

76 yramidal morphology with large and extensive apical dendrites and less extensive basal dendrites.

77 estricted dendritic localization of Npn-2 to apical dendrites and of Npn-1 (also known as Nrp1) to al

78 -40 min, a large Ca(2+) elevation appears in apical dendrites and propagates to the soma.

79 nantly in restricted regions of the proximal apical dendrites and soma of hippocampal CA1 pyramidal n

80 Dual recordings from the apical dendrites and somata of mitral cells show that LL

81 Ca(2+) waves that initiated in the proximal apical dendrites and spread over this region and in the

82 se in dendritic spine density selectively in apical dendrites and subtle changes in dendritic spine m

83 he cell layer giving deep cells long primary apical dendrites and superficial cells short or absent p

84 the size) in diameter than unlabeled, mature apical dendrites and that they had developing synapses o

85 hins increased the extent of only basal, not apical, dendrites and promoted greater elongation than w

86 s asymmetrically localized to the developing apical dendrite, and is required for the chemoattractive

87 ve described inhibitory synaptic contacts on apical dendrites, and an abundant number of GABAergic sy

88 ayer 4 spiny neurons failed to remodel their apical dendrites, and approximately 55% remained as pyra

89 amatergic inputs: parallel fibers synapse on apical dendrites, and auditory nerve fibers synapse on b

90 l area CA1 are remarkably enriched in distal apical dendrites, and this unique distribution pattern i

91 A subset of cells, those with the largest apical dendrites, are plastic, but those with the smalle

92 In contrast to apical dendrites, basal and oblique branches: (1) impose

93 ficial half of the epithelium and with short apical dendrites bearing microvilli.

94 Type 1 cells had apical dendrites bearing numerous dendritic spines with

95 ons of IP3 appear to be confined to the main apical dendrite because uncaging IP3 in the oblique dend

96 stacks of 15-19 somata with pyramidal cells apical dendrites being arranged into distinct vertically

97 They are clearest on the main apical dendrite but also have been detected in the finer

98 present on corticospinal neuronal somata and apical dendrites but were not detected on their projecti

99 ith significantly different densities in the apical dendrites compared with the soma.

100 t mitral-mitral cell gap junctions on distal apical dendrites contain Cx36.

101 Our findings indicate apical dendrite degeneration as a novel cellular patholo

102 Alzheimer's disease (AD), and found profound apical dendrite degeneration of Betz cells in both fALS

103 as a potential intrinsic mechanism for CSMN apical dendrite degeneration.

104 reviously reported progressive CSMN loss and apical dendrite degeneration.

105 , AIS distance inversely correlates with the apical dendrite diameter, and model simulations confirme

106 ines from basal, proximal apical, and distal apical dendrites, differences that are more pronounced w

107 In proximal and distal apical dendrites, different calcium dynamics correlate w

108 show here that the excitability of terminal apical dendrites differs from that of the apical trunk.

109 ing to the cortical plate, neurons extend an apical dendrite directed toward the pial surface.

110 contained complex pyramidal cells with dual apical dendrites displaying nonaccommodating discharge p

111 ging of developing mouse cortex reveals that apical dendrites emerge by direct transformation of the

112 Whether the apical dendrite emerges by transformation of the leading

113 ium ion concentration ([Ca2+]) transients in apical dendrites evoked by sodium action potentials are

114 ype, the "dentate" CA3 pyramidal cell, whose apical dendrites extend into and ramify within the hilus

115 By 96 h after BrdU injection, these apical dendrites extended into the middle of the molecul

116 he majority of neurons in all mice have long apical dendrites extending into cortical layer I.

117 eeper layers of MEC in view of the extensive apical dendrites from deeper cells reaching layers II an

118 neously recorded long-term spine dynamics in apical dendrites from layer 5 pyramidal cells and blood

119 ysis of caged glutamate, individual terminal apical dendrites generated cadmium-sensitive all-or-none

120 in malformed cortex identified as having an apical dendrite had firing patterns similar to control p

121 y, the sADP occurred along the extent of the apical dendrite in CPn and COM neurons.

122 Cells presenting a tufted apical dendrite in layer I have dense terminal fields in

123 n, switching from selective labeling of only apical dendrites in Ammon's horn subregion la (CA1a) to

124 ce correlated with density of thin spines on apical dendrites in CA1, although not with mushroom spin

125 social or restraint stress causes atrophy of apical dendrites in CA3 pyramidal neurons of the hippoca

126 (400 micrograms/ml) also produced atrophy of apical dendrites in CA3.

127 eurogenesis led to atrophy of pyramidal cell apical dendrites in dorsal CA3 and to neuronal reorganiz

128 ed stress induces atrophy, or remodeling, of apical dendrites in hippocampal CA3 pyramidal neurons.

129 urons occurs in the distal branches of their apical dendrites in L1 but not in the perisomatic dendri

130 Monitoring layer 5 neurons' apical dendrites in layer 1, we show that one cellular e

131 diate a specific developmental retraction of apical dendrites in layer VI neurons.

132 the soma and throughout the entire length of apical dendrites in resting pyramidal neurons.

133 lized to layer V pyramidal neurons and their apical dendrites in the cortex, and to pyramidal neurons

134 ations in the morphology of pyramidal neuron apical dendrites in the prelimbic area of the medial pre

135 pplication of a hyperosmotic solution to the apical dendrites in the vicinity of the dendritic whole-

136 campal pyramidal neurons in vitro and toward apical dendrites in vivo.

137 groups of pyramidal neurons (twin and single apical dendrites) in the CA1 region.

138 re recurrent mossy fiber input through their apical dendrites, indicating that these cells are robust

139 The oriented growth of the apical dendrite is regulated by Sema3A, which acts as a

140 rence in output mode between single and twin apical dendrite morphologies, which was consistent with

141 s are generated in the distal portion of the apical dendrite, most likely in the glomerulus.

142 on an outside-out patch was excised from the apical dendrite near the point of stimulation and satura

143 ted microglia closely apposed and ensheathed apical dendrites, neurites, and neuronal perikarya.

144 g uniquely regulates the growth of layer 2/3 apical dendrites; no effects of gene deletion were obser

145 these L1-3 interneurons inhibited the distal apical dendrite of >60% of L5 pyramidal neurons across m

146 The apical dendrite of 86% of the biocytin-labeled HEGCs ext

147 patch-electrode recordings from the soma and apical dendrite of CA1 pyramidal neurons in hippocampal

148 many experimental results recorded from the apical dendrite of L5 pyramidal neurons, the model valid

149 ded the membrane potential from the soma and apical dendrite of layer 5 (L5) pyramidal neurons of the

150 The integration of synaptic inputs to the apical dendrite of layer 5 neocortical pyramidal cells w

151 The apical dendrite of layer V pyramidal neurons in the mPFC

152 l-D-aspartate receptor transmission onto the apical dendrite of layer V pyramidal neurons undergoes l

153 pendent synaptic modification vary along the apical dendrite of rat cortical layer 2/3 pyramidal neur

154 eous whole-cell recordings from the soma and apical dendrite of rat neocortical pyramidal neurons.

155 the activation of Ca(2+) channels along the apical dendrite of the CA1 hippocampal pyramidal neuron

156 subunits were primarily distributed on large apical dendrites of a subset of pyramidal cells from dee

157 Apical dendrites of Betz cells are important sites for t

158 al slices revealed increased staining in the apical dendrites of CA1 neurons.

159 reases with distance from the soma along the apical dendrites of CA1 PCs.

160 Kv4.2-mediated A-type K(+) current along the apical dendrites of CA1 pyramidal cells (CA1 PCs) is res

161 hic factor (BDNF) increased spine density in apical dendrites of CA1 pyramidal neurones in organotypi

162 Voltage-dependent K(+) channels in the apical dendrites of CA1 pyramidal neurones play importan

163 ich are constitutively active at rest in the apical dendrites of CA1 pyramidal neurons and can be fur

164 how that calcium spikes are initiated in the apical dendrites of CA1 pyramidal neurons and drive burs

165 e asymmetric (excitatory) synapses formed on apical dendrites of CA1 pyramidal neurons at 2 months po

166 stimulation (48 h) reduces spine density in apical dendrites of CA1 pyramidal neurons in organotypic

167 from morphologically identified sites in the apical dendrites of CA1 pyramidal neurons in vivo while

168 Moreover, the average spine density on the apical dendrites of CA1 pyramidal neurons is significant

169 tics of excitatory synaptic input across the apical dendrites of CA1 pyramidal neurons using dual who

170 d patch-pipette recordings in the somata and apical dendrites of CA1 pyramidal neurons, we determined

171 e elimination of A-type K+ currents from the apical dendrites of CA1 pyramidal neurons.

172 maturity without affecting spine density in apical dendrites of CA1 pyramidal neurons.

173 ing by making whole-cell recordings from the apical dendrites of CA1 pyramidal neurons.

174 ting of channels and the excitability of the apical dendrites of CA1 pyramidal neurons.

175 kainate receptors located mainly on proximal apical dendrites of CA3 pyramidal cells may be compensat

176 the cell bodies and proximal portion of the apical dendrites of CA3 pyramidal neurons of the postnat

177 and was generated by a current source in the apical dendrites of CA3.

178 HCN1 shows a high level of expression in apical dendrites of cortical pyramidal neurons and in pr

179 oscopy to demonstrate Ca2+ electrogenesis in apical dendrites of deep-layer pyramidal neurons of rat

180 covering the dentate gyrus, CA3c/hilus, and apical dendrites of field CA1, but not for the remainder

181 al extension of the Golgi apparatus into the apical dendrites of hippocampal and neocortical pyramida

182 results in altered spine morphologies along apical dendrites of hippocampal CA1 neurons in vivo.

183 To do so, we recorded from the apical dendrites of hippocampal CA1 pyramidal neurons in

184 From the apical dendrites of hippocampal CA1 pyramidal neurons, w

185 okes large amplitude Ca2+ waves in the thick apical dendrites of hippocampal CA1 pyramidal neurons.

186 ecovery from inactivation of Na+ channels in apical dendrites of hippocampal CA1 pyramidal neurons.

187 tached patch configuration from the soma and apical dendrites of hippocampal CA1 pyramidal neurons.

188 ent (Ih), are selectively targeted to distal apical dendrites of hippocampal CA1 pyramidal neurons.

189 at produces retraction and simplification of apical dendrites of hippocampal CA3 pyramidal neurons, a

190 e enhanced dendritic arborization within the apical dendrites of hippocampal cornu ammonis 1 and gran

191 ptic sites and colocalizes with the NMDAR in apical dendrites of hippocampal neurons.

192 r long-term potentiation (LTP) in the distal apical dendrites of hippocampal pyramidal neurons.

193 uitry, layer 4-3 (L4-L3) synapses, or in the apical dendrites of L5 neurons- but a broad-scale analys

194 eled neurons revealed microglia fused to the apical dendrites of labeled pyramidal neurons.

195 clustered loss of dendritic spines along the apical dendrites of layer (L) 5 pyramidal neurons (PNs)

196 inergic inhibition of NGFCs disinhibited the apical dendrites of layer 2/3 pyramidal neurons by silen

197 Spines on apical dendrites of layer 3 neurons were then characteri

198 py and determined the spine turnover rate of apical dendrites of layer 5 (L5) and L2/3 pyramidal neur

199 The motility of spines on apical dendrites of layer 5 neurons was assayed by time-

200 nscranial two-photon microscopy, we followed apical dendrites of layer 5 pyramidal neurons in the mot

201 we repeatedly imaged dendritic spines on the apical dendrites of layer 5 pyramidal neurons.

202 Both cell types targeted the distal apical dendrites of layer II principal neurons.

203 excitatory postsynaptic currents (EPSCs) in apical dendrites of layer V pyramidal cells of prefronta

204 SF increased the mushroom-type spines on the apical dendrites of layer V pyramidal neurons adjacent t

205 (the NO receptor) was at high levels in the apical dendrites of layer V pyramidal neurons and in par

206 The apical dendrites of many neurons contain proximal and di

207 also unexpectedly found them ubiquitously in apical dendrites of mature hippocampal CA1 and cortical

208 glomerular (PG) cell types interact with the apical dendrites of mitral and tufted cells inside glome

209 In the olfactory bulb, gap junctions between apical dendrites of mitral cells increase excitability a

210 terminals in the upper layers impinge on the apical dendrites of neurons in other layers, suggesting

211 yer were significantly reduced compared with apical dendrites of normotopic granule cells.

212 Incertocortical axons contact the distal apical dendrites of postmigratory cortical pyramidal cel

213 interneurons were shown to synapse on distal apical dendrites of pyramidal cells and to spike prefere

214 genic reporter line, we demonstrate that the apical dendrites of pyramidal cells are abnormally organ

215 (-ir) was particularly dense within primary apical dendrites of pyramidal cells in both hippocampus

216 lecule (NCAM) as they innervate the proximal apical dendrites of pyramidal cells in the CA3 region of

217 t an excitatory feedback mechanism acting on apical dendrites of pyramidal cells in V1 and other area

218 l GABA neurons that terminate exclusively on apical dendrites of pyramidal cells, and 2) a disinhibit

219 In analyses restricted to the apical dendrites of pyramidal cells, greater spine densi

220 4 subunit mRNAs were highly localized to the apical dendrites of pyramidal cells, whereas in interneu

221 al potentials reflect summated potentials of apical dendrites of pyramidal cells.

222 The apical dendrites of pyramidal neurons integrate inputs f

223 llations (field potentials) generated in the apical dendrites of pyramidal neurons.

224 perpolarization in the outer portions of the apical dendrites of pyramidal neurons.

225 mice resulted in elevated spine densities on apical dendrites of star pyramidal cells at both postnat

226 Spine density on apical dendrites of subicular pyramidal cells was determ

227 s undergoes retraction and simplification of apical dendrites of the CA3 pyramidal neurons and synapt

228 stent with a distribution in cell bodies and apical dendrites of the sensory neurons.

229 , S-SDS increases arborization and spines of apical dendrites of these neurons in a D1 receptor-depen

230 led accumulation of autophagosomes along the apical dendrites of vulnerable CSMN at P60, early sympto

231 ema3F-Fc protein induced spine retraction on apical dendrites of wild-type, but not NrCAM-null cortic

232 Basal, but not apical, dendrites of neurons from SNI rats are longer an

233 lude reduced spine density on basal, but not apical, dendrites of pyramidal neurons in the binocular

234 ino acids mediate a reversible remodeling of apical dendrites on CA3 pyramidal cell neurons of the hi

235 Changes did not occur on their apical dendrites or on cells in the dentate gyrus or som

236 rve terminals (input) and mitral/tufted cell apical dendrites (output).

237 end into the stratum oriens-alveus while the apical dendrites project deep into the stratum lacunosum

238 LLDs occur synchronously only in cells whose apical dendrites ramify in the same glomerulus.

239 Only the largest pyramidal cell apical dendrites reached the supragranular layers, and t

240 ptic glutamate receptors across the range of apical dendrites receiving Schaffer collateral input.

241 fields are generated in or near the soma and apical dendrites, respectively.

242 hen JG cell arrival, and finally mitral cell apical dendrite restriction.

243 In addition, pyramidal apical dendrites reveal a distinct motif profile.

244 Classic pyramidal cells had a long apical dendrite, robust basal arbors, and an axon with b

245 Pulsed (pressure) ejection of nicotine onto apical dendrites selectively enhanced EPSPs mediated by

246 ct subset of layer 10 bipolar neurons, whose apical dendrites show a complex transverse arborization

247 addition, electron microscopy of DCX-labeled apical dendrites showed that they were much thinner (1/4

248 y reduced in the first 150 micrometer of the apical dendrites, so that action potentials recorded far

249 imity of postsynaptic densities expressed in apical dendrite spines, which include also the alpha(3)

250 rease in spine density on CA3 pyramidal cell apical dendrites (stratum radiatum) and an increase in t

251 rease in spine density, both on basal and on apical dendrites, suggesting a possible substrate for th

252 al apical dendrites than on basal or primary apical dendrites, suggesting that synaptic efficacy is l

253 layers and were substantially larger in the apical dendrites than in cell body layers or basal dendr

254 nel activity was significantly larger in the apical dendrites than in the soma.

255 with burst capability had less well-branched apical dendrites than nonbursting HEGCs, their dendrites

256 ensity of AMPA receptors was found on distal apical dendrites than on basal or primary apical dendrit

257 of back-propagating action potentials in the apical dendrite that occurs in parallel with long-term p

258 tions in oblique radial branches of the main apical dendrite that were of similar amplitude than thos

259 hanges in the architecture and plasticity of apical dendrites that are particularly evident in the CA

260 ments of mammalian visual cortex, with thick apical dendrites that ascend to layer 1, "intrinsically

261 iented basal dendrites and sparsely branched apical dendrites that ascended to layer I.

262 idal neurons in layer V exhibited undulating apical dendrites that did not reach layer I.

263 Most of these neurons have apical dendrites that extend to the superficial layers a

264 onfined to their parallelly aligned proximal apical dendrites that formed two intensely stained bands

265 The total length and branching of HEGC apical dendrites that penetrated the molecular layer wer

266 roup 1 includes large pyramidal neurons with apical dendrites that reach layer 1 with an apical tuft;

267 t amplitude (0.3-0.6 nA) in the range of CA1 apical dendrites that receive a uniform density of Schaf

268 a change in the relative extent of basal and apical dendrites that results in a gradual sculpting int

269 ayer III while deep pyramidal cells had long apical dendrites that spanned layers I and II.

270 hough boosting was maintained throughout the apical dendrite, the degree of boosting changed nonmonot

271 s pS857 dephosphorylation in distal areas of apical dendrites, the region forming synapses with the i

272 The polarization was biphasic in the mid-apical dendrites; there was a time-dependent shift in th

273 he cell body for variable distances into the apical dendrite; these spikes were found in only a few a

274 In apical dendrites, this increase is accompanied by an equ

275 responsible for the ability of the proximal apical dendrite to control the coupling between the axon

276 the sets of mitral cells that project their apical dendrite to the same glomerulus represent unique

277 lb, principal neurons (mitral cells) project apical dendrites to a common glomerulus where they recei

278 count for the enhanced responsiveness of CA3 apical dendrites to chronic stress and may either be pat

279 widespread inhibition, which shifts from the apical dendrites to somata of pyramidal cells during bur

280 s into primary dendrites and shifts adjacent apical dendrites to the basal pole of the cell.

281 Here we show that the growth of apical dendrites towards the pial surface is regulated b

282 The gross structure and orientation of apical dendrite tufts remained stable over a two-month p

283 Three-dimensional analysis of labeled apical dendrites under an electron microscope revealed t

284 Direct stimulation of distal apical dendrites using focal photolysis of caged glutama

285 Branching patterns of apical dendrites varied as a function of the cell's soma

286 However, the apical dendrite was frequently branched while basal dend

287 Moreover, spine density along the apical dendrite was greater in the knockout mice, which

288 sity on terminal segments of the basilar and apical dendrites was reduced on average by 35 and 20%, r

289 a major excitatory input to the CA3 proximal apical dendrites, we measured ultrastructural parameters

290 ole-cell recordings from the soma and distal apical dendrites were performed and, following the injec

291 release events and spine density on primary apical dendrites were reduced.

292 Spine density and arborization of subicular apical dendrites were significantly related to diagnosti

293 ns (large pyramids with thick nonbifurcating apical dendrites) were found in layer Va of PR; and LS n

294 Ca(2+)-activated channel decreased along the apical dendrite, whereas the density of the large-conduc

295 nt at synapses on basal dendrites but not on apical dendrites, whereas immunolabeling for GluR2/3 is

296 develops into a DGC, consisting of a single apical dendrite with further branches, remains largely u

297 Type 2 cells possessed apical dendrites with greatly reduced spine densities an

298 We find that CSMN display vacuolated apical dendrites with increased autophagy, shrinkage of

299 eptors to synaptically active regions of the apical dendrite without inducing any significant changes

300 matergic terminals, and postsynaptically, at apical dendrites, without inhibiting the soma.