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1 growth factor or by recombination with chick apical ridge.
2 of SHH and factors normally expressed in the apical ridge.
5 f Cek-8 in distal mesenchyme is regulated by apical ridge- and FGF-polarising signals and retinoic ac
7 ngly, we also show that cells which form the apical ridge are initially scattered in a wide region of
11 These data suggest that D-V patterning and apical ridge formation are linked, since they show that
12 link between D-V positional information and apical ridge formation, and discuss the possible functio
13 show that the ability of ectoderm to form an apical ridge in response to FGF4 in both mouse and chick
14 and ventral ectoderm cells contribute to the apical ridge, intermingling to some extent within it.
15 or expansion and cells that were in anterior apical ridge later become incorporated into non-ridge ec
17 p2 and Msx2, genes that are expressed in the apical ridge of normal limb buds, are not expressed in t
18 1 and zona-binding molecules localize to the apical ridge on the acrosome but following cholesterol e
19 owth Factor (FGF), in addition to ectodermal apical ridge removal experiments suggest the existence o
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