ライフサイエンスコーパス: apical surface

1 relocalize proteins from the cytosol to the apical surface.

2 e with ciliated and nonciliated cells on its apical surface.

3 e together with these foci toward the future apical surface.

4 corresponding hinge areas of the urothelial apical surface.

5 ed network of ciliary basal bodies below the apical surface.

6 a large pre-apical compartment (PAC) to the apical surface.

7 e by which uroplakins were inserted into the apical surface.

8 n decreased the association of sgk1 with the apical surface.

9 e primary cilium at the abneural edge of the apical surface.

10 mechanotransduction organelle located on the apical surface.

11 ly to the circumference of the cell near its apical surface.

12 comitans when the bacteria were added to the apical surface.

13 al domains and assemble junctions near their apical surface.

14 tor H regulates complement activation on the apical surface.

15 racterized by effacement and blebbing of its apical surface.

16 ically inhibited nuclear movement toward the apical surface.

17 into foci and for foci to accumulate at the apical surface.

18 e hair bundle that protrudes from the cell's apical surface.

19 a brush border containing microvilli on the apical surface.

20 e furrow, most re-establish contact with the apical surface.

21 ial plaques) covering >90% of the urothelial apical surface.

22 issorted CAR from recycling endosomes to the apical surface.

23 the G(M1), integrin, microvillus-containing apical surface.

24 phase plates oriented perpendicularly to the apical surface.

25 t that CAIV may have a role in buffering the apical surface.

26 to maintain cytoskeletal flexibility at the apical surface.

27 tribute to the antiadhesive character of the apical surface.

28 AQP2 between intracellular vesicles and the apical surface.

29 d arrays in bottle cells, emanating from the apical surface.

30 d Caco-2 cells occurred predominantly at the apical surface.

31 ithin the epithelium it is restricted to the apical surface.

32 binds PtdIns(4,5)P2 and is recruited to the apical surface.

33 Anx2 binds Cdc42, recruiting it to the apical surface.

34 Cdc42 recruits aPKC to the apical surface.

35 subsequent deposition of fibronectin on the apical surface.

36 try and an impermeable tight junction at the apical surface.

37 es its constitutive exocytic delivery to the apical surface.

38 transferring MeV to HAE when applied to the apical surface.

39 diate fusion of transcytotic vesicles at the apical surface.

40 y, decreasing the amount of NKCC2 at the TAL apical surface.

41 the stereocilia that project from the cells' apical surface.

42 otein VAMP3, and they co-localize at the TAL apical surface.

43 , either close to or in association with the apical surface.

44 ed bacteria are trafficked to and across the apical surface.

45 microvilli to become motile over the dorsal/apical surface.

46 they co-localize in discrete domains at the apical surface.

47 he proper positioning of motile cilia on the apical surface.

48 sition of the substrate protein on the GroEL apical surface.

49 gth of the gut and do not share a continuous apical surface.

50 entify the mechanisms that target Dia to the apical surface.

51 s insufficient to reroute this mutant to the apical surface.

52 f a primary cilium, the kinocilium, at their apical surface.

53 cal tension without substantial shrinking of apical surfaces.

54 yosin II apically but fail to contract their apical surfaces.

55 Each hair cell contains at the apical surface a bundle of stereocilia.

56 owever, a transcytotic protein did reach the apical surface after a prior appearance basolaterally.

57 NTHi formed adherent biofilms on the apical surface airway epithelia with decreased susceptib

58 ctivated GPCR (Oxgr1) increased on the PP-IC apical surface, allowing paracrine delivery of alpha-KG

59 ized trafficking of podocalyxin to the early apical surface--an important event in vascular lumenogen

60 ystem creates microaerobic conditions at the apical surface and aerobic conditions at the basolateral

61 bules, endolyn is variously localized to the apical surface and endosomal/lysosomal compartments.

62 ll cycle, with M-phase being confined to the apical surface and G1-, S-, and G2-phases occurring at m

63 uid absorption to prevent dehydration of the apical surface and increased cilia beating in these epit

64 actin-filament-rich structures at the dorsal-apical surface and induces structures with greater actin

65 Formation of the apical surface and lumen is a fundamental, yet poorly un

66 , or aPKC prevents normal development of the apical surface and lumen.

67 lpha-2,6-linked sialic acid receptors on the apical surface and supports productive replication of bo

68 Transcellular dendrites scanned the M-cell apical surface and the gut luminal content; they were ab

69 ecular mechanisms by which NKCC2 reaches the apical surface and their role in renal function and main

70 lium (RPE), anomalously expressed CAR at the apical surface and was highly susceptible to adenovirus

71 The remnant then moves along the apical surface and, once proximal to the centrosome at t

72 undred actin filaments that arise from their apical surfaces and that bear the mechanotransduction ap

73 d cell-cell adhesions had nuclei with curved apical surfaces and variable heights.

74 e PfCHT1) are both localized on the ookinete apical surface, and both are present in micronemes.

75 lateral surface than after adsorption to the apical surface, and it was dependent on JAM-A.

76 to alter the geometry of cell shapes at the apical surface, and that cell shape then determines the

77 totic spindle, mispositioning of the nascent apical surface, and ultimately, the formation of aberran

78 uncations resulted in receptor missorting to apical surfaces, and they indicated an essential targeti

79 ivering fusiform vesicles, as well as at the apical surface; and 4) the hinge-associated MAL may play

80 regulate the presence of microvilli on their apical surface are largely unknown.

81 al EGF receptor activation that may regulate apical surface area changes during bladder filling.

82 DA-Rab11a stimulated an increase in apical surface area in the absence of stretch, whereas D

83 addition to providing a means for amplifying apical surface area, we propose that microvilli function

84 s, amnioserosa cells undergo oscillations in apical surface area.

85 essed in epidermal cells and secreted to the apical surface as a putative component of the embryonic

86 characterize forces driving emergence of an apical surface as single nascent cells are added to a ve

87 g process involving the de novo formation of apical surface at secondary lumina, and that radial inte

88 RSV was shed exclusively from the apical surface at titers consistent with those in airway

89 2, binds to the collagen-binding site on the apical surface between the two immunoglobulin-like domai

90 nt reduction in susceptibility to HSV at the apical surface but had little impact on basolateral infe

91 ed basolateral proteins such as VSV-G to the apical surface, but do not cause mis-sorting of membrane

92 Depletion of extracellular Ca(2+) at the apical surface, but not basolateral surface, also preven

93 e with a perpendicular long axis and a small apical surface, but the long axis rather then the size o

94 myosin (NMY-2Colon, two colonsGFP) at their apical surfaces, but in either sax-7(eq1) or hmr-1(RNAi)

95 (UP) Ia, a major glycoprotein of urothelial apical surface, can serve as the receptor for the FimH l

96 in VDCs under microaerobic conditions at the apical surface, compared to results under aerobic condit

97 n and neurogenesis was shifted away from the apical surface, consistent with increased pro-proliferat

98 Apical surface defects in ome- and crb2b-deficient anima

99 e hypothesized that NKCC2 endocytosis at the apical surface depends on dynamin-2 and clathrin.

100 demonstrate that Wg is endocytosed from the apical surface devoid of DFz2 via a dynamin-independent

101 Stresses applied via integrins at the apical surface directly displaced podosomes near the bas

102 hat line the intestinal tract, remodel their apical surface during differentiation to form a brush bo

103 tiguous duct that largely separates from the apical surface during PAC fusion.

104 ximal to the centrosome at the center of the apical surface, enables cilium formation.

105 align at metaphase in the long length of the apical surface except in cells undergoing unequal cleava

106 finding that Rfx2 cell-autonomously controls apical surface expansion in nascent MCCs.

107 , MAL increases the S256 phosphorylation and apical surface expression of AQP2.

108 ha enhanced membrane PIP2 levels and reduced apical surface expression of ENaC in CCD cells, down-reg

109 naling lead to inverted polarity so that the apical surfaces face the surrounding ECM.

110 analyzed protein expression patterns in the apical surface fluid (ASF) from aberrantly differentiate

111 By contrast, apical surface formation in control MDCK cells required

112 pparently significantly lower remains at the apical surface, from where its uptake occurs.

113 s with a perpendicular cleavage plane at the apical surface generate symmetrical cell fates, whereas

114 nocilia, or bind directly to the hair cells' apical surface if cilia are absent [MZovl injected with

115 ltiple pericentrin-stained centrioles at the apical surface, (ii) expression of transcription factor

116 Whole cell or apical surface immunoprecipitation demonstrated increase

117 ring cell division to correctly position the apical surface in a growing epithelial structure.

118 ells undergo epithelialization and create an apical surface in contact with a cavity, a fundamental e

119 e cell periphery in early embryos and at the apical surface in pharyngeal and intestinal epithelial c

120 During mitosis, Pins is mislocalized to the apical surface in the absence of Par3 or by inhibition o

121 tself sufficient to reroute a protein to the apical surface in the presence of a strong basolateral s

122 Their apical surface, in contact with aqueous humor is hexagon

123 lation to the amount of virus applied to the apical surface, indicating transcytosis efficiency was c

124 ain, newly enveloped virions are directed to apical surfaces instead of to cell junctions.

125 f the SG epithelium, loss of AdamTS-A causes apical surface irregularities and cell elongation defect

126 toreceptor outer segments (POSs) and the RPE apical surface is compromised.

127 , optic vesicle cells shorten, drawing their apical surfaces laterally relative to the basal lamina,

128 oss NCI-H441 lung epithelial cell layers and apical surface liquid (ASL) volumes are coupled to dexam

129 ), sub-clones were assessed for growth rate, apical surface morphology, epithelial barrier function a

130 e conclude that cAMP stimulates steady-state apical surface NKCC2 by stimulating exocytic insertion a

131 Confocal imaging of apical surface NKCC2 in isolated perfused TALs confirmed

132 NKCC2 endocytosis and maintain steady-state apical surface NKCC2 in native THALs.

133 cted modules: "NPHP1-4-8" functioning at the apical surface, "NPHP5-6" at centrosomes, and "MKS" link

134 minoglycan hyaluronic acid is present on the apical surface of airway epithelial cells.

135 inosa, is initiated by TLR2 displayed on the apical surface of airway epithelial cells.

136 E facilitated the uptake of antigen from the apical surface of an epithelial monolayer by diverting a

137 lament-rich mechanosensory structures at the apical surface of auditory and vestibular hair cells.

138 M complexes, we found that residues from the apical surface of C1q [where the scFv3(V) epitope was lo

139 Par6B localizes to the apical surface of Caco-2 cysts and is required to recrui

140 pic actin bundles are seen across the entire apical surface of cells.

141 le information on cortex organization at the apical surface of cells.

142 hich are observed at excessive levels at the apical surface of CF airway epithelial cells.

143 were expressed at 32 receptors/mum(2) on the apical surface of choroid plexus epithelial cells.

144 ted in exposure of terminal galactose on the apical surface of conducting airway epithelial cells, as

145 the prevention of bacterial adherence to the apical surface of corneal epithelial cells and suggest t

146 NTHi formed biofilms on the apical surface of cultured airway epithelia.

147 Static adhesion assays showed that the apical surface of differentiated HCLE cells expressing M

148 ture showed the HS binding site to be at the apical surface of E2, with variants affecting the electr

149 to generate a cystlike structure, where the apical surface of each epithelial cell faces a fluid-fil

150 At the apical surface of each hair cell, the proteins display p

151 raphy of kidney showed F-Dapa binding to the apical surface of early proximal tubules.

152 positioning them in direct contact with the apical surface of either intercalated or principal cells

153 to transport LPL from the basolateral to the apical surface of endothelial cells.

154 ween SIgA and CD71 or CD71 and Tgase2 at the apical surface of enterocytes in biopsy samples and mono

155 GPAT3 was abundantly expressed in the apical surface of enterocytes in the small intestine.

156 mation beneath the infecting bacteria on the apical surface of enterocytes.

157 -like transmembrane protein expressed on the apical surface of epithelia, where it protects the cell

158 in and localize to cell junction area at the apical surface of epithelia.

159 ne-associated mucins, MUC1 and MUC16, on the apical surface of epithelial cells and that both mucins

160 te that microtubule alignment underneath the apical surface of epithelial cells follows cell shape.

161 the delivery of polymeric IgA and IgM to the apical surface of epithelial cells via transcytosis.

162 s associated with myosin accumulation at the apical surface of epithelial cells, as seen in the verte

163 chored proteins (GPI-APs) are located at the apical surface of epithelial cells.

164 motes ENaC biogenesis and trafficking to the apical surface of epithelial cells.

165 This encodes a chloride ion channel on the apical surface of epithelial cells.

166 d DUOX protein specifically localized to the apical surface of epithelial cells.

167 F5) of gp41 or to cardiolipin (IS4) onto the apical surface of epithelial monolayers prior to inocula

168 ent to HEp-2 cells, is not detectable at the apical surface of HAE cell cultures where RSV enters.

169 t the second ion channel is expressed at the apical surface of hair cells and that it contains the Pi

170 as immature stereocilia and kinocilia on the apical surface of hair cells.

171 mary receptor; however, AAV2.5T binds to the apical surface of human airway epithelia at higher level

172 ms regulating adenosine elimination from the apical surface of human airway epithelia.

173 ed out by exposing sera and SIVmac251 to the apical surface of human endometrial carcinoma (HEC-1A) c

174 cretory duct begins as buds of chitin at the apical surface of individual secretory cells.

175 potent neutrophil chemoattractant, from the apical surface of infected model intestinal epithelium.

176 ion, which results in the contraction of the apical surface of ingressing cells.

177 tidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and

178 ed in the appearance of hCFTR protein at the apical surface of intestinal glands in Cftr-/- hCFTR-G54

179 tein homologues (PfRhs) are expressed at the apical surface of invasive merozoites and have divergent

180 r cluster transmembrane glycoproteins at the apical surface of ionocytes.

181 and vestibular hair cells and also along the apical surface of Kolliker's organ during cochlear devel

182 amics of single MRV virions and ISVPs at the apical surface of live polarized Madin-Darby canine kidn

183 e and the localization of active cSrc at the apical surface of luminal epithelial cells during lactat

184 usly unappreciated actomyosin network at the apical surface of Madin-Darby canine kidney cells.

185 The apical surface of mammalian bladder urothelium is covere

186 IP8, ZIP14 transporters are localized on the apical surface of MDCK-ZIP cells; and 6) like ZIP8, ZIP1

187 of stereociliary bundle (hair bundle) on the apical surface of mechanosensory hair cells (HCs) dictat

188 al expression of biglycan and decorin on the apical surface of MEE, combined with the evidence that t

189 e (55 mmHg for 50 ms) at 26 degrees C to the apical surface of mouse and human nasal epithelial cells

190 nstrate polarized expression of C5aR1 on the apical surface of mouse embryonic neural progenitor cell

191 tethered mucin glycoprotein expressed on the apical surface of mucosal epithelial cells.

192 ts reveal impaired basal body docking to the apical surface of multiciliated cells.

193 t that initially locates peripherally at the apical surface of one of the daughter cells.

194 nstrate that these interactions occur at the apical surface of polarized airway tissues.

195 cay-accelerating factor (DAF or CD55) at the apical surface of polarized Caco-2 cells results in rapi

196 t binding of P. aeruginosa aggregates to the apical surface of polarized cells led to the striking fo

197 or the first time to visualize events at the apical surface of polarized cells.

198 P-gp in each case is localized on the apical surface of polarized cells.

199 Microvilli are membrane extensions on the apical surface of polarized epithelia, such as intestina

200 sorting signals that direct proteins to the apical surface of polarized epithelial cells are complex

201 The apical surface of polarized epithelial cells receives in

202 We now show that CD317 is expressed at the apical surface of polarized epithelial cells, where it i

203 and N-formyl-Met-Leu-Phe application to the apical surface of polarized gut epithelial cells resulte

204 ally enter through and are released from the apical surface of polarized human endothelial monolayers

205 MUC1 is efficiently delivered to the apical surface of polarized Madin-Darby canine kidney (M

206 apical proteins take different routes to the apical surface of polarized Madin-Darby canine kidney ce

207 the ability of the bacteria to adhere to the apical surface of polarized T84 epithelial cells was mea

208 l stimulation, such as fluid flow across the apical surface of renal epithelial cells.

209 al infection, reovirus was released from the apical surface of respiratory epithelia and did not disr

210 n to photoreceptor inner segments and to the apical surface of retinal pigment epithelial cells where

211 of the noninhibitory antibody RV6-25 on the apical surface of RV VP6 head domain does not obstruct t

212 EPEC attaches to the apical surface of small intestine enterocytes, causing m

213 ate a contractile myosin II network near the apical surface of supporting cells.

214 ignificant accumulation of hyaluronan on the apical surface of the AECs in response to ER stress, but

215 tic U937 cells adhered at 4 degrees C to the apical surface of the AECs subjected to ER stress by a m

216 ated myosin light chain were enriched at the apical surface of the airway epithelium during monopodia

217 -derived hydrogen peroxide released from the apical surface of the airway epithelium.

218 nsitive hair bundle which protrudes from the apical surface of the cell into a narrow fluid-filled sp

219 ational; the position of basal bodies on the apical surface of the cell.

220 ded to an increase in ENaC expression at the apical surface of the cells and was not present when an

221 (PMCA2), which transports calcium across the apical surface of the cells into milk.

222 evealed that RhoA and AQP2 accumulate at the apical surface of the collecting duct.

223 ocates from an intracellular location to the apical surface of the endometrial epithelium during the

224 or the recruitment of naive monocytes to the apical surface of the endothelium and for the migration

225 -lipoxygenase activity, is secreted from the apical surface of the epithelial barrier and establishes

226 tion step is the detachment of PMNs from the apical surface of the epithelium and their subsequent re

227 The apical surface of the epithelium constitutes the first p

228 m, Upd forms a concentration gradient on the apical surface of the follicular epithelium with a peak

229 ells delaminates from and migrates along the apical surface of the glandular epithelium toward the pr

230 ons that collaborate to build the functional apical surface of the intestinal epithelium in vivo.

231 molecular function of Ezrin in building the apical surface of the intestinal epithelium was not clea

232 rumbs proteins are localized normally to the apical surface of the lulu mutant epiblast and neural pl

233 their terminal mitosis, they detach from the apical surface of the neuroepithelium.

234 rase active-site residues are located at the apical surface of the passenger, at the entrance of a la

235 ng potential that approximates the OS to the apical surface of the RPE to facilitate phagocytosis.

236 stereociliary bundles that project from the apical surface of the sensory hair cells.

237 ls in the hair bundles that project from the apical surface of the sensory hair cells.

238 however, about how forces produced near the apical surface of the tissue are transmitted within indi

239 On the apical surface of these renal epithelia, aldosterone inc

240 SMCT was reported in the apical surface of thyrocytes and formerly proposed also

241 Fibronectin (FN)-binding activity on the apical surface of trophoblast cells is strengthened afte

242 children and has a selective tropism for the apical surface of well-differentiated human airway epith

243 Apical surfaces of cells and their nuclei in monolayers

244 e core PCP protein Vangl2 is detected at the apical surfaces of cells at the blastopore lip, and it f

245 of aquaporin 1 unexpectedly appeared at the apical surfaces of CLIC4-suppressed RPE cells, together

246 ter heart development, a lumen forms between apical surfaces of contralateral cardioblasts (CBs).

247 (LET-4 and EGG-6) that are expressed on the apical surfaces of epidermal cells and some tubular epit

248 , PDZK1, forming a macromolecular complex at apical surfaces of gut epithelia.

249 n the mouse inner ear, GPSM2 is localized to apical surfaces of hair cells and supporting cells and i

250 membranous yet extracytoplasmic niche on the apical surfaces of host epithelial cells, a process that

251 bactericidal activity were determined on the apical surfaces of human and rat airway epithelia and on

252 tors on primary mouse splenocytes and on the apical surfaces of human mucosal epithelial cell monolay

253 of juvenile animals localized EsGal1 to the apical surfaces of light-organ epithelia and surrounding

254 bule-nucleating protein gamma-tubulin at the apical surfaces of naive epithelial cells.

255 d orientation of this polarity such that the apical surfaces of neighboring cells all point toward th

256 short and static MV in confluent cells, the apical surfaces of nonconfluent epithelial cells (ECs) f

257 chondroitin sulfate proteoglycans (CSPGs) on apical surfaces of palatal medial edge epithelial (MEE)

258 When applied to apical surfaces of polarized epithelial cells in monolay

259 t current) when added to basolateral but not apical surfaces of polarized monolayers of Colony-29 cel

260 Addition of fibronectin to the apical surfaces of polarized T84 cell monolayers augment

261 Apical surfaces of proliferating epithelial sheets have

262 lpha and their localization primarily to the apical surfaces of RPE cells.

263 the modified microvilli projecting from the apical surfaces of the sensory hair cells of the inner e

264 d that Dragon localized predominantly to the apical surfaces of tubular epithelial cells in the thick

265 aces of this cluster, but does not reach the apical surface or penetrate into the cluster.

266 FMNL3 and RhoJ are concentrated at the early apical surface, or AMIS, and regulate the formation of r

267 hat must maintain great flexibility at their apical surface; our results suggest that CRIPs function

268 for HSV entry, sorted preferentially to the apical surface, overlapping with adherens and tight junc

269 Here, we identify new roles for two apical surface proteins - Cadherin 99C (Cad99C) and Stra

270 ubule-based directed movement of a subset of apical surface proteins.

271 scopy showed that virions were surrounded by apical surface protrusions and that virus was present in

272 marily expressed in the cytoplasm and at the apical surface rather than in the mitochondria and that

273 Trafficking of NKCC2 to the apical surface regulates NKCC2-mediated NaCl absorption

274 Our data suggested that TMPRSS2, an apical surface serine protease, may have a normal role i

275 resulting nonthrombogenic and nonimmunogenic apical surface significantly delays the onset of rejecti

276 red to be delivered to the entire lateral or apical surface, suggesting-contrary to expectations-that

277 morphological changes, as the normally flat apical surface swelled into a dome.

278 old more susceptible to HSV infection at the apical surface than at the basolateral surface.

279 oximal tubules, with greater uptake from the apical surface than from the basolateral surface.

280 After transcytosis to the apical surface, the extracellular, ligand-binding portio

281 al cells with a specialized structure at the apical surface, the mechanosensitive hair bundle.

282 s DLG-1 within adherens junctions and at the apical surface, thereby generating arcade cell polarity.

283 nvolves relocalization of the virus from the apical surface to intercellular tight junctions.

284 pylobacter endosome intracellularly from the apical surface to the basolateral surface occurred over

285 e a majority of their HA onto their ciliated apical surfaces to form a heavy chain hyaluronan (HC-HA)

286 emed to be triggered by changes to astrocyte apical-surface topography in response to nanoroughness.

287 rete HIV virions from the basolateral to the apical surface via polymeric Ig receptor (pIgR)-mediated

288 e of TECs was exposed to serum than when the apical surface was exposed.

289 Hexagonality of the apical surface was maintained by the interaction between

290 tachment of M. genitalium to the host cell's apical surface was observed directly and confirmed using

291 he presence of HCO(3)(-), was greater on the apical surface, was reduced on the apical side by ACTZ,

292 ation demonstrated the loss of ENaC from the apical surface when UCH-L3 was inhibited.

293 basal side (where DNA is synthesized) to the apical surface (where mitosis takes place); such nuclear

294 n from the interendothelial cell area to the apical surface, where JAM-A played a role as a leukocyte

295 n increased the association of sgk1 with the apical surface, whereas methyl-beta-cyclodextrin decreas

296 translocation of the cell body away from the apical surface while morphologically rounded up in M pha

297 and that progeny virus is released from the apical surface with little apparent gross cytopathology.

298 ilayers with filters and inoculated on their apical surfaces with 10(6) colony-forming unit bacteria,

299 ion, leading to inappropriate positioning of apical surfaces within the cyst.

300 bly is primed by centrosome migration to the apical surface, yet surprisingly little is known about t