ライフサイエンスコーパス: apoE receptor

1 by an isoform-specific process that requires apoE receptors.

2 activation and decreased JNK activation via apoE receptors.

3 petes with Abeta for cellular uptake through apoE receptors.

4 ing them to cellular catabolism via neuronal APOE receptors.

5 apoE3:Abeta complex formation and uptake by apoE receptors.

6 complexes despite proper expression of other APOE receptors.

7 ApoE Receptor 2 (ApoER2) and the very low density lipopr

8 density lipoprotein receptor (VLDLR) and the apoE receptor 2 (ApoER2) as well as a cytosolic adaptor

9 y was to determine the effect of X11alpha on ApoE receptor 2 (ApoEr2) trafficking and the functional

10 low density lipoprotein (VLDL) receptor and apoE receptor 2 (apoER2), are also receptors for Reelin,

11 elin and apolipoprotein E (apoE), ligands of apoE receptor 2 (ApoER2), are involved in retinal develo

12 cts with amyloid precursor protein (APP) and apoE receptor 2 (apoEr2), increases their levels on the

13 ntially spliced isoform of an ApoE receptor, ApoE receptor 2 (Apoer2), is essential for protection ag

14 osely related LDLR family members, VLDLR and ApoE receptor 2 (ApoER2), proteins implicated in both ne

15 bly mutant for the VLDL receptor (VLDLR) and ApoE receptor 2 (ApoER2), show disorders of cerebral cor

16 t F-spondin interacts with an apoE receptor (apoE receptor 2 [ApoEr2]) through the thrombospondin dom

17 to negatively charged cellular surfaces and ApoE receptor 2.

18 low density lipoprotein receptor (VLDL), and apoE receptor-2 in mouse aortic smooth muscle cells.

19 ery low density lipoprotein receptor and the apoE receptor-2, in the transmission of extracellular si

20 ells isolated from LDLR-null, VLDL-null, and apoE receptor-2-null mice were responsive to apoE inhibi

21 The apolipoprotein E (apoE) receptor-2 (apoER2), another member of the LDL rec

22 We demonstrate that ApoE binding to ApoE receptors activates dual leucine-zipper kinase (DLK

23 Over the past few years, apolipoprotein E (ApoE) receptors, also known as LDL receptor-related prot

24 ApoE, ApoE receptors and APP cooperate in the pathogenesis of

25 (VLDLR) is a multi ligand apolipoprotein E (apoE) receptor and is involved in brain development thro

26 rotein that interacts with apolipoprotein E (ApoE) receptors and controls neuronal positioning during

27 emonstrated that F-spondin interacts with an apoE receptor (apoE receptor 2 [ApoEr2]) through the thr

28 that a differentially spliced isoform of an ApoE receptor, ApoE receptor 2 (Apoer2), is essential fo

29 Our previous data demonstrate that the apoE receptor ApoEr2 co-precipitated with APP and sugges

30 ission by signaling through the postsynaptic ApoE receptors Apoer2 and Vldlr and thereby potently enh

31 ation experiments an interaction between the apoE receptor, ApoEr2, and NMDAR1 through their extracel

32 ase cleavage of APP and an apolipoprotein E (apoE) receptor, ApoER2.

33 ApoE receptors are essential for the development of the

34 Neuronal ApoE receptors are linked to learning and memory, but th

35 ted for by the interaction with the proposed ApoE receptor binding region; therefore, we speculate th

36 Using single chain multimers of the apoE receptor-binding domain (N-apoE), we also show that

37 ited by a synthetic peptide derived from the apoE receptor-binding region.

38 xists as to whether a single lipid-activated apoE receptor-binding site within a particle is capable

39 Thus, the impairment of apoE receptor-dependent neuromodulation may contribute t

40 lly-lipidated apoE from premature binding to apoE receptors during receptor biogenesis.

41 acts with APP as well as with members of the apoE receptor family.

42 ed mRNA and protein for an apolipoprotein E (ApoE) receptor family member, SorLA (LR11) has been foun

43 The expanding roles of ApoE receptors for cellular signal transduction at the s

44 ApoE receptors have been indirectly implicated in memory

45 n receptor-related protein 1 (LRP1), a major apoE receptor in the brain that is abundantly expressed

46 nsity lipoprotein receptor (LDLR) is a major apoE receptor in the brain that strongly regulates amylo

47 Since LDLR is a major apoE receptor in the brain, we hypothesized that rs688 m

48 oE and apoJ levels and the potential role of apoE receptors in astrocyte activation have not been add

49 en be cleared from the interstitial space by apoE receptors in the brain or become part of an extrace

50 mer's disease , a direct or indirect role of ApoE receptors in the disease process is likely.

51 ing in mice to investigate possible roles of ApoE receptors in the regulation of neuronal survival.

52 eceptor-associated protein (RAP), suggesting apoE receptor involvement, ATP-stimulated migration was

53 Intriguingly, the ApoE receptor LRP4 and APP are also required for normal

54 Interaction with apoE receptors may not mediate the toxic actions of apoE

55 propose a model in which Abeta, Reelin, and ApoE receptors modulate neurotransmission and thus synap

56 Blocking LRP1, an apoE receptor on the neuronal membrane, also blocked the

57 receptor-associated protein, an inhibitor of apoE receptors, particularly the LDL-receptor-related pr

58 gle nucleotide polymorphisms (SNPs) in brain apoE receptors represent excellent candidates for associ

59 summary, these studies identify a functional apoE receptor SNP that is associated with AD in a sex-de

60 model for studying the relationships between ApoE receptors, tau hyperphosphorylation, and Alzheimer'

61 The primary apoE receptor that regulates levels of apoE in the brain

62 Two apolipoprotein E (apoE) receptors, the very low density lipoprotein (VLDL)

63 These data suggest that apoE receptors translate the presence of extracellular A

64 receptor-associated protein, an inhibitor of apoE receptors with a differential affinity for the low

65 tery, but the numerous critical functions of ApoE receptors within and outside the nervous system tha