ライフサイエンスコーパス: appear normal

1 ced fertility, although adult pex5-10 plants appear normal.

2 MET currents of heterozygous littermates appear normal.

3 xocytosis markers in rsd-2 and rsd-6 mutants appear normal.

4 tivation and arterial-venous differentiation appear normal.

5 cranial neural crest-derived enteric neurons appear normal.

6 eterozygous for the null allele, Sox2(EGFP), appear normal.

7 tor or the IGF-1 receptor plus one Ir allele appear normal.

8 mesenchymal transition (EMT) at gastrulation appear normal.

9 ough signaling, morphology, and cargo levels appear normal.

10 pe, whereas lamin, Ran, and tubulin staining appear normal.

11 membranes, although non-neuronal cell types appear normal.

12 e other populations of somatosensory neurons appear normal.

13 mice express OVA mRNA in the epidermis, and appear normal.

14 mice are born at the expected frequency and appear normal.

15 Lrat+/+ mice, whereas other neuronal layers appear normal.

16 At 1 year of age, CPLXII knockout (KO) mice appear normal.

17 ence of Itk, but the T cells that do develop appear normal.

18 eas the aerial part of the ABCG1-RNAi plants appear normal.

19 t presents focally; most renal tubular cells appear normal.

20 Other cell types in the immune system appear normal.

21 however, 53BP1 DSB responses in these cells appear normal.

22 Wild type and heterozygote mice appear normal.

23 movement is unaffected, and mitotic spindles appear normal.

24 ir follicle architecture and differentiation appear normal.

25 commitment in distal Runx1 knockout embryos appears normal.

26 mation and maintenance of adherens junctions appears normal.

27 of the dorsal FC whereas ventral/orbital FC appears normal.

28 hibited, whereas slow-muscle gene expression appears normal.

29 se stages, the synaptic physiology phenotype appears normal.

30 , nuclear transport of transcription factors appears normal.

31 obal systolic function of the left ventricle appears normal.

32 morphogenesis fails, although lens formation appears normal.

33 ugh the number of cell-surface Ca2+ channels appears normal.

34 ified by anaphase and chromosome segregation appears normal.

35 s and initial patterning of the hindlimb bud appears normal.

36 e marrow cells for T- and B-cell development appears normal.

37 Duct/gland development appears normal.

38 nvasion, and a compromised barrier; the lens appeared normal.

39 in allele yielding only wild-type prelamin A appeared normal.

40 level, and T-cell receptor (TCR) repertoire appeared normal.

41 t and malformed, whereas in renal cysts they appeared normal.

42 n these images, but the parts that were seen appeared normal.

43 ty was significantly diminished, but the ONL appeared normal.

44 For example, pstO cell differentiation appeared normal.

45 hR density on the remaining junctional folds appeared normal.

46 , moribund animals resumed linear growth and appeared normal.

47 erator and diaphragm neuromuscular junctions appeared normal.

48 tion, polarity, and photoreceptor morphology appeared normal.

49 n the shape and density of the cone pedicles appeared normal.

50 e ventral cord and peripheral nervous system appeared normal.

51 hereas single-transgenic littermate controls appeared normal.

52 The epithelium and Descemet's membrane appeared normal.

53 e initial generation of central 5-HT neurons appeared normal.

54 ntiation of the liver and endocrine pancreas appeared normal.

55 at the nevus margin, the choroid and sclera appeared normal.

56 orta and collagen fibrils in the aortic wall appeared normal.

57 and TH-IR amacrine cell somas and dendrites appeared normal.

58 d found that sensory neurons and motoneurons appeared normal.

59 oleus and quadriceps muscles from MGSKO mice appeared normal.

60 rin, c-kit, adaptin-3, and the HPS1 protein) appeared normal.

61 opaminergic amacrine cells, and Muller cells appeared normal.

62 In the newborn period, their joints appeared normal.

63 n particular, hematopoietic cell development appeared normal.

64 Retinas appeared normal.

65 The overall morphology of the hippocampus appeared normal.

66 ion in the parabrachial nucleus and amygdala appeared normal.

67 ction, the rate of collagen type I secretion appeared normal.

68 ponsive neurons for which responses to faces appeared normal.

69 horter body axis but cell fate specification appeared normal.

70 that decussate to more caudal brain segments appeared normal.

71 ation of viral replication compartments also appeared normal.

72 eir morphology, activation, and cargo levels appeared normal.

73 By week 6, the skin appeared normal.

74 er wild-type littermates) in all tissues and appeared normal.

75 eproductive organs and spermatozoid motility appeared normal.

76 tiation, whereas Th1 and Th2 differentiation appeared normal.

77 the podocyte markers GLEPP1 and synaptopodin appeared normal.

78 We found that heart development appeared normal after endodermal deletion of Nkx2.5 wher

79 esis of CTSC and neutrophil serine proteases appeared normal along with initial processing and sortin

80 ponses of this mutant to nitrogen limitation appear normal, although the strain is also somewhat more

81 The heterozygous mice appeared normal, although the protein level was reduced.

82 Fundus examination usually appears normal, although optic nerve alterations like op

83 Surprisingly, homozygous Wisp3 mutant mice appear normal and do not recapitulate any of the morphol

84 ypoplastic, although their early progenitors appear normal and exhibit no premature differentiation o

85 ers of Lrat-/- mice upon histologic analysis appear normal and show no histological signs of liver fi

86 Granule and Purkinje cell dendrites appear normal and the former have typical numbers of exc

87 Kidneys of CnA-beta -/- mice appear normal and the mice develop with no phenotypic ab

88 Tpst2(+/-) mice appear normal and, when interbred, yield litters of norm

89 Adult heterozygous mice appeared normal and exhibited no evidence of Hailey-Hail

90 onditions, all stages of virus morphogenesis appeared normal and extracellular virions were detected

91 ertheless, all stages of virus morphogenesis appeared normal and extracellular virions were present o

92 The striatum as well as substantia nigra appeared normal and no loss of dopamine expressing cells

93 n contrast, the heterozygous (SM2(+/-)) mice appeared normal and reproduced well.

94 Unexpectedly, assembly and morphogenesis appeared normal and the noninfectious virus particles we

95 k or absent, although its adnexal expression appeared normal and the punctate membrane staining of Cx

96 Initial movements of the germ cells appear normal, and wild-type numbers of germ cells popul

97 in-1-deficient mice, podocyte ultrastructure appeared normal, and the podocyte proteins synaptopodin,

98 null (DUSP9(-/y)) embryos developed to term, appeared normal, and were fertile.

99 While cell polarity appears normal, and chromosome and furrow positioning re

100 The dopaminergic system of LRRK2(-/-) mice appears normal, and numbers of dopaminergic neurons and

101 acellular signal-regulated kinase) signaling appears normal, and phosphoinositide 3-kinase (PI3K)-pro

102 Although axon outgrowth and elongation appear normal, antisense morpholino knockdown of pcdh18b

103 Germinal centers and plasma cells in tonsils appeared normal, as were serum immunoglobulin levels.

104 ulation, axial patterning of the neural tube appears normal, as assessed by in situ hybridization for

105 Here, we report that alphaMHC-cyclin T1 mice appear normal at baseline yet suffer fulminant apoptotic

106 virus type 1 (HIV-1)-transgenic mice (Tg26) appear normal at birth but die within 3 to 4 weeks.

107 Hair numbers appear normal at birth but gradually decrease to <50% of

108 ufficiency of the Grb2 gene (Grb2(+/-) mice) appear normal at birth but have defective T cell signali

109 calcium, calciotropic hormones, and skeleton appear normal at birth in the offspring of mothers who a

110 disruption of the PURA gene in both alleles appear normal at birth, but at 2 weeks of age, they deve

111 ecifically in lung alveolar epithelial cells appear normal at the age of 6 weeks, when exposed to lon

112 ly retarded CNS myelination; however, myelin appeared normal at 3 months of age.

113 h four (1.4%) of 238 articular surfaces that appeared normal at arthroscopy.

114 onic development, but haploinsufficient mice appeared normal at birth and were fertile.

115 BHD heterozygous knockout (BHDd(/+)) mice appeared normal at birth but developed kidney cysts and

116 These mutant mice appeared normal at birth but failed to gain weight appro

117 Sgpp1(-/-) mice appeared normal at birth, but during the 1st week of lif

118 GBDK mice appeared normal at birth, but they soon stopped growing,

119 DN-Raf mice appeared normal at birth, were fertile, and had normal c

120 sing an osteoprogenitor-specific Cre driver, appeared normal at birth; however, these mice showed sev

121 Although villus morphology appeared normal at E16.5, the first time at which both G

122 aphragm and foot process-associated proteins appeared normal at early stages.

123 Major blood vessels appeared normal at embryonic day 9.5.

124 ly two Atmsh2-1, but all 36 wild-type lines, appeared normal at G5.

125 se, and the stomach and adjacent lymph nodes appeared normal at surgery.

126 Mice deficient in TSP-1, despite appearing normal at birth, develop a chronic form of ocu

127 While retinal morphology appears normal at birth and during early postnatal devel

128 Head circumference appears normal at birth, with a significantly increased

129 The resulting proteasomes appear normal but assemble inefficiently, facilitating i

130 Mice heterozygous for a Tbx2 null mutation appear normal but homozygous embryos reveal a crucial ro

131 Female AR(-/-) mice appear normal but show longer estrous cycles and reduced

132 The MUV-E108Q meta I --> meta II transition appeared normal but the MUV-E108Q meta II decay to opsin

133 NA under the control of its native promoter, appeared normal but were male sterile due to delayed ant

134 ated in the Col10alpha1-Cre-expressing cells appeared normal but were osteopenic.

135 neural responses in hyperplastic ICC tissues appeared normal but were up-regulated in the cecum, wher

136 The mice appeared normal but, after 7 weeks, developed reduced bo

137 Sp-nanos1 and 2 knockdown embryos initially appear normal, but do not develop adult rudiments; altho

138 ith later JHm treatments, extension programs appear normal, but retraction programs are maintained be

139 n 12-month-old knockout mice, photoreceptors appear normal, but the apical processes of the retinal p

140 atellite cell activation and myoblast fusion appear normal, but there is a reduction in early neutrop

141 cells in alpha9, alpha10, and alpha9/10 KOs appeared normal, but a quantitative analysis was not per

142 mon lymphoid progenitors and pre-pro-B cells appeared normal, but cells at subsequent stages of B lym

143 These mice appeared normal, but cultured fibroblasts and macrophage

144 At birth, epidermal cilia mutants appeared normal, but developed basaloid hyperplasia and

145 lls, from embryogenesis onwards, osteoblasts appeared normal, but haematopoietic stem and progenitor

146 PS treatment, quantitative parameters of URs appeared normal, but in the two MSG-treated hamsters tha

147 ent cardiomyocytes within the left ventricle appeared normal, but intercellular junctions were ill-fo

148 croRNA guide strand selection by ALG-1(anti) appeared normal, but microRNA* strand release was ineffi

149 ment of key midzone-stabilizing proteins all appeared normal, but microtubule polymerization was neve

150 of Lrp4, the organization of the hippocampus appeared normal, but the frequency of spontaneous releas

151 DNA double-strand break formation appeared normal, but the recombination pathway was defec

152 Chondrocyte maturation appeared normal, but the zone of hypertrophic chondrocyt

153 Akinetes in the mutant strain appeared normal, but these cultures were less resistant

154 Oocytes from mutant females appeared normal, but were severely maturation-defective

155 Cardiovascular and blood pressure regulation appears normal, but the integrity of sympathetic adrener

156 Male-female sexual behavior appears normal, but trp2 mutant males also vigorously mo

157 Purified vdeltaD10 virions appeared normal by microscopic examination and biochemic

158 present in Evc(-/-) mice and Gli3 processing appears normal by western blot analysis.

159 nstrated that quantitative TCR diversity can appear normal despite qualitative changes in repertoire

160 ain activations associated with movement may appear normal despite residual functional impairment.

161 although tracheal patterning and maturation appear normal during embryogenesis.

162 In the cortex, the structure of myelin appeared normal during development and in the adult; how

163 Although hair follicles appeared normal during development, they were morphologi

164 Embryonic/fetal muscle development appears normal during transgene expression, however, pos

165 Although active zones appear normal, electrophysiological recordings in cerebe

166 mozygous targeted mutant (Stamp(tm/tm)) mice appear normal except for marked decreases in male fertil

167 let-7-C knockout flies appear normal externally but display defects in adult be

168 have generated dube3a null mutants, and they appear normal externally, but display abnormal locomotiv

169 of conditioned and unconditioned stimuli but appear normal following a more robust five-pairing train

170 s equivalent to one endogenous allele (G0.5) appeared normal for a period of about 3-4 months, but at

171 he healing of serosal injury to intact bowel appeared normal given the reduced inflammatory response.

172 Dlx5/6(+/-) mice, which appear normal histologically, show spontaneous electrogr

173 st of the surviving neurons in these animals appeared normal histologically, particularly motor neuro

174 AE3 null mice appeared normal, however, and AE3 ablation had no effect

175 The flagella of the luxS mutant appeared normal; however, in genetic backgrounds lacking

176 rfollicular epidermis of Fntb-deficient mice appeared normal; however, keratinocytes from these mice

177 ture of corneodesmosomes and tight junctions appeared normal, immunohistochemistry for claudin 1 show

178 m, optic nerve, and spinal cord white matter appear normal in Aspa(nur7/nur7) mice.

179 cell responses in two viral infection models appear normal in both magnitude and the hierarchy of ant

180 nd subcellular localization of clathrin also appear normal in conv mutants.

181 increased cone and rod spacing in areas that appear normal in conventional images, suggesting that ph

182 MPOD is commonly depleted but may appear normal in early stage MacTel.

183 HSP) 40 at the spokehead-spokestalk juncture appear normal in length and composition but twitch activ

184 and cleavage furrows of cortical stem cells appear normal in magoo.

185 Retinal inputs appear normal in mutants, and clock gene rhythms within

186 ma (Pip4k2c), the gene encoding PI5P4Kgamma, appear normal in regard to growth and viability but have

187 The microtubule arrays appear normal in the embryonal mass cells, but the micro

188 Learning and memory appear normal in the heterozygous animals.

189 However, microtubule morphology and function appear normal in the mmd4 mutant.

190 important for callosal axon midline crossing appear normal in the transgenic mice, suggesting that th

191 In the foveal area, the RPE layer appeared normal in 45.5% of eyes, while small RPE elevat

192 region of the macula in all eyes, whereas FA appeared normal in 9 of 18 eyes (50%).

193 egrity of emerin-deficient nuclear envelopes appeared normal in a nuclear microinjection assay.

194 The alpha-globin genes themselves have appeared normal in all ATMDS patients studied to date.

195 internal models in self-generated movements appeared normal in autism.

196 chondrocytic zones of the growth plates also appeared normal in BGsKO mice.

197 Pollen development appeared normal in both CTF7 knockout and overexpression

198 Although epidermal homeostasis appeared normal in both transgenic and knockout mice, wo

199 lear focus formation and mono-ubiquitination appeared normal in BRCA2-deficient cells.

200 activation and the number of Ca(2+) channels appeared normal in Cabp2(LacZ/LacZ) mice, as were ribbon

201 Although B cell development appeared normal in CD83-/- mice, B and CD4+ T cell expre

202 Axon growth appeared normal in cultured knock-out neurons.

203 Cilia structure/number appeared normal in galectin-3-null mutants.

204 fibroblasts was reduced in individual 1 but appeared normal in individual 2.

205 the locomotor-stimulating effects of cocaine appeared normal in KOR(-/-) mutants, but was exaggerated

206 ic ganglia and innervation of target tissues appeared normal in mice lacking a core planar cell polar

207 1 foci formation and mitomycin C sensitivity appeared normal in MRG15-binding defective PALB2 mutants

208 omplexes, desmosomes, and basement membranes appeared normal in mutant embryos, indicating that proce

209 ugh thymocyte and splenic T-cell populations appeared normal in mutant mice, T-cell proliferation in

210 t occurs immediately after theta stimulation appeared normal in mutant slices but the newly formed po

211 -term potentiation and long-term depression, appeared normal in NP-deficient mice.

212 r organization, and liver lipid contents all appeared normal in Phd(2/3)hKO mice.

213 PD-derived iPS cells containing the mutation appeared normal in phenotypes, karyotype, and pluripoten

214 es of epidermal proliferation and cell death appeared normal in PPAR-alpha-/- mice.

215 tened or absent, whereas cellular lamination appeared normal in retinas at 5 dpf.

216 lial marker fli1a and vascular morphogenesis appeared normal in scube1 morphants.

217 Tendon progenitors appeared normal in Scx-/- embryos and a phenotype result

218 Most myenteric neurons also appeared normal in size, but NO-producing myenteric neur

219 te was only marginal, and embryo development appeared normal in the absence of apyrases.

220 r of oligodendrocyte progenitor cells (OPCs) appeared normal in the Erk2 conditional knock-out cortex

221 Basal and starvation-induced autophagy appeared normal in the nca1 and cat2 mutants.

222 dorsal horn increased in the OP-controls but appeared normal in the NRP/GRP group.

223 Whereas KOR(-/-) mice appeared normal in the open field and light/dark box tes

224 Retinal vascular development appeared normal in the TRAIL(-/-) mice, except for a sma

225 r, the lens shape, polarity and transparency appeared normal in the transgenic mice.

226 Cone morphology and electrophysiology appeared normal in transgenic animals up to 7 months of

227 Airway branching also appeared normal in Twist2-IKKbetaca embryos, with airway

228 ultrastructure of the chloroplast, however, appears normal in cls8-1 leaves.

229 Although at birth the subventricular zone appears normal in mice lacking Hedgehog signaling, by po

230 , bone marrow central B cell selection in MS appears normal in most patients.

231 Phosphorylation of CTD serines 2 and 5 appears normal in mutant cells, suggesting that Bur1 is

232 Although cell spreading appears normal in R760A mutant-integrin cells compared w

233 hromatin loading of FA core complex proteins appears normal in RAD18-knockout cells.

234 on of basal bodies, but the cilium structure appears normal in Root mutant neurons.

235 n, NT and NT receptor expression resumes and appears normal in taste buds and nerves.

236 Spermatogenesis up to and including meiosis appears normal in the absence of GLD2, but post-meiotic

237 The nervous system appears normal in the absence of PAK5, as do other tissu

238 e the development of immune cell populations appears normal in these animals, we show enhanced interl

239 the paradoxical picture of a person who may appear "normal" in some aspects, and yet hate himself an

240 Although myofibrillogenesis appeared normal, in knockdown hearts the tissue integrit

241 Other cholesterol transport pathways appear normal, including the movement of cholesterol fro

242 Mutant imb1 plants appear normal, indicating that IMB1 is involved in regul

243 Minus-strand synthesis by PI cells appeared normal; it was dependent on continuous P123 and

244 Although cell polarity appeared normal, Klf5 mutant embryos arrested at the bla

245 Whereas lst-1 and sygl-1 single mutants appear normal, lst-1 sygl-1 double mutants are phenotypi

246 ctedly, that whereas blood vessel morphology appeared normal, lymphatic-blood vessel separation was i

247 ility of heterozygous NS-null (NS(+/-)) mice appeared normal, NS(+/-) mouse embryonic fibroblasts (ME

248 Zymogen granules in the GP2 knock-out mice appeared normal on electron microscopy and contained the

249 While the swimming pattern of mutant cells appeared normal, on swarm plates, mutant cells exhibited

250 e ileocecal valve and to evaluate whether it appeared normal or abnormal.

251 cell specification in the anterior pituitary appears normal, patterning in the ventral diencephalon i

252 though light-/dark-adapted total cGMP levels appeared normal, Pde6b(H620Q) homozygotes exhibited depr

253 While ureter and bladder histology appeared normal, postnatal day (P) 1 mutants had high ra

254 However, iRhom2(-/-) mice appear normal, raising questions about how ADAM17 is reg

255 ed events in both Fyn-/- and Fyn/Lck-/- mice appear normal, reinforcing the theme of redundancy in th

256 Cilia of klp-6 mutants appear normal, suggesting a defect in sensory neuron fun

257 the developing brain of MeHg-exposed embryos appeared normal, suggesting that the mechanism leading t

258 ans of null (-/-) mice, cholinergic staining appeared normal, suggesting that the overall gross devel

259 Notably, arterial development appears normal, suggesting that morphogens from the skul

260 heterozygous for the targeted Calcrl allele appear normal, survive to adulthood, and reproduce.

261 ion of activation-induced cytidine deaminase appear normal, the cell line does not hypermutate an ind

262 While adhesion to fibrinogen and collagen appeared normal, the platelets in thrombi from P2Y12-/-

263 ment of the inner ear and lateral-line organ appeared normal, the sensory epithelium showed progressi

264 Although collagen fibril assembly initially appeared normal, the tendons of Mkx(-/-) embryos express

265 though NFkappaB, c-Jun, and ATF-2 activation appears normal, the LPS-induced activation of IFNbeta re

266 and phenotype of MZ B cells in CD36-/- mice appeared normal, there was a minor block in the transiti

267 gene mutation alone, cerebellar histogenesis appears normal, thereby demonstrating functional redunda

268 hough cells from heterozygous DDB2(+/-) mice appeared normal, these mice had enhanced skin carcinogen

269 angential migration of immature interneurons appears normal, they develop dendritic and axonal proces

270 The number of cone cells appeared normal throughout the superior and inferior ret

271 r alteration in lignin structure, the plants appear normal under standard conditions in the greenhous

272 Although hematopoiesis appears normal under steady-state conditions, Cdk6(-/-)

273 required for survival, mice that lack RAMP3 appear normal until old age, at which point they have de

274 Mice appeared normal until about 24 h before death.

275 FS-treated retinas appeared normal until ED 8, when they showed a reduction

276 Many mitochondria appeared normal until they showed outer membrane swellin

277 Meiocytes from mutant plants appeared normal up to diakinesis, when they exhibited si

278 the absence of Tmod1, embryonic development appeared normal up to embryonic day (E) 8.5.

279 Once formed, Rad51-K191R-DNA filaments appeared normal upon electron microscopic inspection, bu

280 Whether regions of the lung that appear normal using traditional computed tomography crit

281 nd callus tissue produced from rescued seeds appeared normal when grown in the presence of His but ty

282 al white matter architecture and myelination appear normal, when crossed with an antioxidant response

283 vation and subsequent ubiquitination of EGFR appear normal, whereas downstream EGFR degradation is de

284 Heterozygous animals appear normal, whereas Nfic(-/-) mice have unique tooth

285 Nondividing somatic cell nuclei appeared normal, whereas dividing cells had abnormal nuc

286 of recombination proteins AtRAD51 and AtMSH4 appears normal, whereas the numbers of AtMLH1 and AtMLH3

287 Activity-evoked responses appear normal while both excitatory and inhibitory spont

288 Cells transfected with pcDNA3.1 vector alone appeared normal, while cells expressing the PetS260A mut

289 Embryos treated in this way appear normal with respect to some known functions of De

290 The homozygous Cacng4-targeted mutant mouse appeared normal with no ataxic gait or absence seizures,

291 he NMU peptide-deficient mice, NMUR2 KO mice appeared normal with regard to stress, anxiety, body wei

292 r the engulfment stage, although sporulation appeared normal with the lower levels of gerA or gerK ov

293 In SHP2(CS) mice, T cell development appears normal with regard to both negative and positive

294 the aortic structure of Nec-1s-treated mice appeared normal, with continuous and organized elastin l

295 he Apc-deficient crypts in Apc(CKO/CKO) mice appeared normal, with morphological transformation, incl

296 earts of hyperleptinemic ACS-transgenic mice appeared normal, with normal echocardiograms and cardiac

297 Primordial germ cell migration appeared normal within Ft mutant embryos; however, germ

298 onic lethality, heterozygous ubc13(+/-) mice appeared normal, without alterations in immune cell popu

299 wever, the skin of untreated Cav-1 null mice appeared normal, without any evidence of epidermal hyper

300 Whereas null mutants of CUL3 appear normal, yeast cells lacking CUL8 have a slower gr