ライフサイエンスコーパス: appendage

1 exocuticle of an impact-resistant crustacean appendage.

2 oblasts were not detected in the left atrial appendage.

3 atients underwent closure of the left atrial appendage.

4 disruption, and exclusion of the left atrial appendage.

5 serted into the incision in the right atrial appendage.

6 apons, such as the mantis shrimp's raptorial appendage.

7 nces in the number of the respiratory dorsal appendages.

8 and a chelate limb followed by two biramous appendages.

9 e to the plasma membrane via mother-specific appendages.

10 rom their body and toward these nonessential appendages.

11 rive overall development of the skin and its appendages.

12 nsferases is expressed specifically in adult appendages.

13 ee different cell types in larval salamander appendages.

14 enhancer for development of these different appendages.

15 gulatory elements affect development of both appendages.

16 -type Ca(2+) channels located on the lobular appendages.

17 cinergic synapses at their dendritic lobular appendages.

18 oral labrum is the remnant of paired frontal appendages.

19 bral ganglia at the origin of paired frontal appendages.

20 , and transformation of head limbs to larger appendages.

21 These lack fully assembled horn appendages.

22 mental affiliation of anomalocaridid frontal appendages.

23 sidue peptides that are used as the antibody appendages.

24 Galalpha(1,4)-GlcNAc and Manbeta(1,4)-GlcNAc appendages.

25 hout using flagella, pili, or other external appendages.

26 Feeding stages show regressed locomotor appendages.

27 during development for the formation of skin appendages.

28 pecialization in both abdominal and thoracic appendages.

29 ed by the segmental affinity of the cephalic appendages [1, 4-6].

30 more familiar sclerotized forms with jointed appendages [1-3].

31 s bound to an affinity-generating lipophilic appendage, a polyethylene glycol-based linker and the NT

32 eostatic conditions and after exfoliation or appendage amputation.

33 by oxidative cleavage of the terminal vinyl appendage and a Takai olefination with pinacol dichlorom

34 cells, accelerated centriole maturation and appendage and cilia formation on the nascent centrioles,

35 l and lateral regions of the developing wing appendage and reduced levels of Dpp affects similarly th

36 -activity relationships that focused on both appendage and skeletal features yielded a nanomolar inhi

37 Here we analyse details of appendage and soft-tissue preservation in Yunnanolimulus

38 oskeleton is well documented by fossils, but appendage and soft-tissue preservation is extremely rare

39 , and mechanical properties of the raptorial appendage and the carapace under long-term ocean acidifi

40 ho and para directing groups in the aromatic appendage and/or by sterically demanding silyl groups.

41 hian dinosaur Kulindadromeus as feather-like appendages and alternatively proposes that the compound

42 rvous system, the segmental identity of head appendages and the early evolution of eyes and their und

43 filaments and rings at the neck of cellular appendages and/or at the cleavage furrow to help compart

44 d (SMR) domain, but the functions of the SMR appendage are unknown.

45 In Cc2d2a(-/-) MEFs, subdistal appendages are lacking or abnormal by transmission elect

46 , including the modular nature by which some appendages are patterned by Hox gene inputs.

47 The skin epidermis and its appendages are subjected to daily assaults from the exte

48 bunit, one on the hinge and the other on the appendage, are necessary and sufficient for functional c

49 ganglia, associated with pre-ocular frontal appendages, as characters of the last common ancestor of

50 s early during the development of ectodermal appendages-as early as the embryonic placode stage-and p

51 ural maturation of the centrioles and timely appendage assembly.

52 re atrial contractions, from the left atrial appendage at a coupling interval of 200 ms in 7 healthy

53 veral analogues substituted with aminopropyl appendages at C5 displayed dominant TLR8-agonistic activ

54 Monogenean parasites have attachment appendages at their haptoral regions that help them to m

55 ysed oxidation to characterize their n-alkyl appendages attached to aromatic cores.

56 The appendage bears long, slender and equally spaced ventral

57 Biopsies were obtained from the right atrial appendage before and after aortic cross-clamping.

58 alize and quantify how incorporation into an appendage blastema broadens the progeny contributions of

59 FTACP possesses 8:2 fluorotelomer side chain appendages bound to the polymer backbone via ester moiet

60 s integral to the diverse patterning of skin appendages, but the molecular events underlying their sp

61 tions in patterning surface ectoderm and its appendages by controlling division orientation.

62 iquids or crawl on surfaces by rotating long appendages called flagella.

63 specialized class of mineralizing epithelial appendages called odontodes.

64 Ubiquitous microbial appendages called pili are involved in sensing surfaces

65 Cell surface appendages called pili play an important role in adhesio

66 The morphology and range of motion of appendages can be revealed in fossils; however, biologic

67 orin protein core, uncovered in human atrial appendages, can regulate the local bioavailability of an

68 using multiple Type IV Pili (TFP), motorized appendages capable of force generation via linear extens

69 Left atrial appendage closure (LAAC) and nonwarfarin oral anticoagul

70 assess composite data regarding left atrial appendage closure (LAAC) in 2 randomized trials compared

71 The risk-benefit ratio of left atrial appendage closure (LAAC) versus systemic therapy (warfar

72 Left atrial appendage closure (LAAC) was approved by the U.S. Food a

73 llation) trial demonstrated that left atrial appendage closure (LAAC) with the Watchman device (Bosto

74 Safety data on percutaneous left atrial appendage closure arises from centers with considerable

75 The implantation of left atrial appendage closure device (WATCHMAN, Boston Scientific, N

76 verview of current transcatheter left atrial appendage closure devices and review the results associa

77 er the past decade, percutaneous left atrial appendage closure has emerged as a valid alternative to

78 mes associated with percutaneous left atrial appendage closure is higher in the real-world population

79 tcomes and costs of percutaneous left atrial appendage closure procedure in the US.

80 In the PROTECT AF (Watchman Left Atrial Appendage Closure Technology for Embolic Protection in P

81 Left atrial appendage closure with the device (n = 463) or warfarin

82 view the results associated with left atrial appendage closure, focusing on procedural and late outco

83 During left atrial appendage closure, the estimated dose absorbed by partic

84 In the study, we performed left atrial appendage closure.

85 These appendages consist of long tubular structures that protr

86 with convergent similarity to arthropods in appendage construction.

87 constituent of this spatially confined beta2 appendage contact interface and is phosphorylated in num

88 t innervate axial muscles, those innervating appendages converge at a specialized structure, the plex

89 locaridids, the Fezouata taxon combines head appendages convergently adapted for filter-feeding with

90 The distal appendages (DAPs) of centrioles are involved in the dock

91 The hair-like cell appendages denoted as type IV pili are crucial for biofi

92 nt genetic underpinnings: canonical genes of appendage development control posterior fin development

93 results suggest that the genetic circuit for appendage development evolved an androgen regulatory inp

94 n animal models by stimulation of ectodermal appendage development with EDAR agonists.

95 components of the EDA pathway disrupt normal appendage development, leading to the human disorder hyp

96 that these transcription factors play during appendage development, their target genes and the mechan

97 DAR) gene, a key regulator of embryonic skin appendage development.

98 l to investigate the molecular basis of skin appendage differences.

99 s of these findings with regard to L protein appendage domain structure and putative domain-domain in

100 hen either domain was coexchanged with other appendage domains.

101 , which interact with the C-terminal ear (or appendage) domains of the beta4 and subunits of AP-4, re

102 Jointed exoskeletons permit rapid appendage-driven locomotion but retain the soft-bodied,

103 Tribolium castaneum, which develops ventral appendages during embryogenesis that later metamorphose

104 associated muscles (e.g., apical muscle) and appendages (e.g., tube feet and papulae).

105 Pili are fibrous appendages expressed on the surface of a vast number of

106 mordia contribute to both ventral and dorsal appendage fates.

107 ys a pretelsonic segment bearing non-walking appendages, features as-yet known in all vicissicaudatan

108 Specifically, although the appendage floor in Drosophila melanogaster is formed thr

109 , jet propulsion, undulatory locomotion, and appendages for movement.

110 a microphagous suspension feeder, using its appendages for sweep-net capture of food items down to 0

111 , demonstrating the specificity of subdistal appendages for these events.

112 To extend the analysis of dorsal appendage formation to include morphogenesis, we develop

113 pe changes and neighbor exchanges underlying appendage formation.

114 peded accumulation of appendage proteins and appendage formation.

115 agellum are related pathogenicity-associated appendages found at the surface of many disease-causing

116 Type IV pili (T4P) are filamentous appendages found on many Bacteria and Archaea.

117 Left atrial appendages from 239 patients stratified by coronary arte

118 METHODS AND Human CPCs from the right atrial appendages from children of different ages undergoing ca

119 Human CPCs from the right atrial appendages from children of different ages undergoing ca

120 Right-atrial appendages from control sinus rhythm patients or patient

121 In contrast, atrial appendages from patients in persistent atrial fibrillati

122 a cleavage site that was not found in atrial appendages from patients in sinus rhythm.

123 ins were identified in left and right atrial appendages from the same patients.

124 onic placode stage-and plays a role in adult appendage function.

125 a mechanism by which the Sp factors control appendage growth through the Notch signaling.

126 The predatory appendage had significantly higher % Mg under ocean acid

127 In this setting, thrombus in the left atrial appendage has been found to be the source of stroke in 9

128 lly results from thrombus in the left atrial appendage has led to the development of mechanical appro

129 The diversification of paired appendages has been a major factor in the evolutionary r

130 zodiazepines bearing easily functionalizable appendages has been developed by ring-opening of activat

131 ce, an understanding of the origin of paired appendages has remained elusive.

132 amyocardial blood vessels of the left atrial appendage have an increased CML presence and proinflamma

133 oupling, thereby generating the observed pCA appendages; however p-coumarates also acylate arabinoxyl

134 On the other hand, Hox genes specify appendage identities along the anteroposterior axis inde

135 Optimization of the core and aryl appendage improved oral absorption and culminated in the

136 del explains why the straight position of an appendage in a fluid flow is unstable and how it stabili

137 Regeneration of a lost appendage in adult amphibians and fish is a remarkable f

138 y higher in blood vessels of the left atrial appendage in AF patients as compared to controls, indepe

139 o demonstrate that the filamentous epidermal appendages in a new specimen of the Jurassic paravian An

140 eliminated or converted into functional skin appendages in a niche-dependent manner.

141 It is plausible that organisms with appendages in a separated flow use this newly discovered

142 We amputated appendages in a variety of cave-adapted and surface-dwel

143 e, we describe a genetic pathway that shapes appendages in Drosophila by defining the pattern of glob

144 obtain homeotic transformations of embryonic appendages in response to Tc-hth or Tc-exd RNAi.

145 llination mechanism involving bulbous stamen appendages in the Neotropical genus Axinaea (Melastomata

146 remnant of the evolutionary history of this appendage, in which cells of the subcoxa of the leg coal

147 ahorses use their tails as flexible grasping appendages, in spite of a rigid bony armor that fully en

148 nd, is essential for the development of skin appendages including the breast.

149 al segments are present in all post-antennal appendages, including the first molecular evidence of a

150 portunity to revisit and better characterize appendage-independent bacterial motility.

151 specify proximal vs. distal identity within appendages independently of Hox genes during this stage.

152 5 (Tbx5), a gene indispensable for pectoral appendage initiation and development.

153 cles associated with mother centriole distal appendages into a larger ciliary vesicle.

154 platform subdomain of the AP-2 beta2 subunit appendage is a privileged CLASP-binding surface that rec

155 orth Greenland, and propose that its frontal appendage is specialized for suspension feeding.

156 ntity of segments and the evolution of their appendages is a prime concern of arthropod evolution stu

157 nectivity between the spinal cord and paired appendages is key to the superior locomotion of tetrapod

158 and lateral diffusion and exchange with skin appendages is presented.

159 Odf2, associated with subdistal appendages, is absent and ninein is reduced in mutant ME

160 to undergo empirical electrical left atrial appendage isolation along with extensive ablation (group

161 tiveness of empirical electrical left atrial appendage isolation for the treatment of LSPAF.

162 (Effect of Empirical Left Atrial Appendage Isolation on Long-term Procedure Outcome in Pa

163 procedures, empirical electrical left atrial appendage isolation was performed in all patients.

164 sa behavior is affected by its motility, and appendages known as flagella and type IV pili (TFP) are

165 was quantified by the ratio of PVfast to LA appendage (LAA) AF CL.

166 Randomized trials of left atrial appendage (LAA) closure with the Watchman device have sh

167 ical electrical isolation of the left atrial appendage (LAA) could improve success at follow-up.

168 Left atrial appendage (LAA) electric isolation is reported to improv

169 rization of left atrial (LA) and left atrial appendage (LAA) flow dynamics in patients with atrial fi

170 The left atrial appendage (LAA) has been identified as a predominant sou

171 Prophylactic exclusion of the left atrial appendage (LAA) is often performed during cardiac surger

172 Electric left atrial appendage (LAA) isolation (LAAI) may occur during cathet

173 Transcatheter left atrial appendage (LAA) ligation may represent an alternative to

174 Left atrial appendage (LAA) ligation with the Lariat device is being

175 ular atrial fibrillation (NVAF), left atrial appendage (LAA) occlusion was noninferior to warfarin fo

176 Left atrial appendage (LAA) procedures have been developed to isolat

177 on of a pyrazolo[1,5-a]pyridine heterocyclic appendage led to a series of high-affinity dopamine rece

178 hich also triggers the acquisition of distal appendage markers on daughter centrioles and the loss of

179 Despite its importance for providing appendage mobility, the genetic program that drives nerv

180 and paired appendages, which is crucial for appendage mobility.

181 utionary developmental origins with pectoral appendage motor systems.

182 e the ability to produce both unusually fast appendage movement and limb force needed for locomotion.

183 polarity-based origin for the variability of appendage number in S. pattersoni.

184 R-21 levels in isolated myocytes from atrial appendages obtained from patients in sinus rhythm and wi

185 el oral anticoagulants, Watchman left atrial appendage occlusion device (DEVICE), and warfarin.

186 ite-specific therapy directed at left atrial appendage occlusion has been now studied for stroke prev

187 a suitable isostere for the anthranilic acid appendage of 4, which led to the discovery of standout a

188 to the poly(A) tail, resulting in C-terminal appendage of a polylysine tract and a terminally stalled

189 In this study, we demonstrate that appendage of a single asparagusic acid residue (AspA tag

190 w has evolved to appreciate that the dynamic appendage of different types of ubiquitin chains represe

191 ological investigations by imaging a walking appendage of Euperipatoides rowelli, a representative of

192 conduction velocity (CV) in the left atrial appendage of patients with AF.

193 The pelvic girdle and appendage of tetrapods is dramatically larger and more r

194 es has been knowledge of the pelvis and hind appendage of their closest fish relatives.

195 rmed on DNA from lymphocytes and left atrial appendages of 34 patients (25 with AF).

196 The appendages of arthropods and vertebrates are not homolog

197 pods, or with the paired antenniform frontal appendages of living Onychophora and some Cambrian lobop

198 Myostatin expression was decreased in atrial appendages of patients with persistent atrial fibrillati

199 to show that, as in ciliogenesis, the distal appendages of the CTL mother centriole contact the plasm

200 ily focused on the sulfonamide and benzamide appendages of the scaffold.

201 ctures are variably homologized with jointed appendages of the second (deutocerebral) head segment, i

202 paralogues of Hox genes are revealed in the appendages of two species of horseshoe crabs.

203 head segment, including antennae and 'great appendages' of Cambrian arthropods, or with the paired a

204 luding type IV pili, bacterial extracellular appendages often essential for attachment to host cells.

205 Lateral appendages often show allometric growth with a specific

206 of the southern portion with an acetaldehyde appendage on the cyclobutane of the northern sector.

207 luding the chelicerae, five pairs of walking appendages, opisthosomal appendages with book gills, mus

208 of a gut, coelom, anterior differentiation, appendages, or internal organs that would suggest a bila

209 The star consists of 22 fleshy appendages, or rays, that are covered in Eimer's organs.

210 The dorsal appendages, or respiratory filaments, of these eggshells

211 Here, by studying expression of appendage patterning genes in embryos and larvae of the

212 Vertebrate appendage patterning is programmed by Hox-TALE factor-bo

213 pathways: the sex determination pathway, the appendage patterning pathway, the insulin/IGF signaling

214 es, or gnathostomes, have two sets of paired appendages, pectoral and pelvic fins in fishes and fore-

215 docks into an elongated groove on the beta2 appendage platform.

216 pili are prototypical bacterial cell-surface appendages playing essential roles in mediating adhesion

217 The distal appendage protein Cep164 appears to be a key actor invol

218 PtdIns(4)P binding to TTBK2 and the distal appendage protein CEP164 compromises the TTBK2-CEP164 in

219 trast, the essential mother centriole distal appendage protein CEP164 did not play a role in either p

220 Sclt1 gene, which encodes a centriole distal appendage protein important for ciliogenesis.

221 , we identified a mother centriole subdistal appendage protein, cenexin, as a critical player in symm

222 erfering RNA (siRNA) targeting of the distal appendage protein, Cep83, required for membrane contact

223 Inhibition of Plk1 impeded accumulation of appendage proteins and appendage formation.

224 ion, showing abnormal localization of distal appendage proteins and failing to remove the ciliation i

225 Second, the stamen appendages provide a hexose-rich, highly nutritious (15,

226 cco, which not only show well-preserved head appendages providing key ecological data, but also eluci

227 signaling and cellular mechanisms underlying appendage regeneration in mice and suggest new therapeut

228 osteoblast dedifferentiation is specific to appendage regeneration, a special feature of the lepidot

229 le parallels between lungfish and salamander appendage regeneration, including strong downregulation

230 nctional studies of positional memory during appendage regeneration.

231 deficient, restricting our understanding of appendage regeneration.

232 involved in social challenge and vertebrate appendage regeneration.

233 ntly diminished, thereby permitting scarless appendage regeneration.

234 erful model system for the study of limb and appendage regeneration.

235 f the four distinct regions encompassing the appendage region of vesicular stomatitis virus (VSV) Ind

236 us system on tissue replacement in mammalian appendages remain largely undefined.

237 as the % Ca and mechanical properties of the appendage remained unchanged.

238 However, its effectiveness on skin appendages remains to be confirmed in vivo.

239 at these excitatory synapses are formed onto appendages resembling dendritic spines, spines have not

240 y heal with scar, as characterized by dermal appendage restoration and organized collagen architectur

241 flower for consumption, air contained in the appendage's aerenchymatous tissue is pressed into the ho

242 e highly correlated in 233 human left atrial appendage samples.

243 Here, by characterizing centriole subdistal appendages (sDAP) in cells exclusively growing submerged

244 Centrioles acquire subdistal appendages (sDAPs) during primary cilium formation.

245 distribution of core components of subdistal appendages (SDAs) and of recycling endosomes, which may

246 In the appendages, shape arises from tension generated by cell

247 fossilized CNSs, even when exoskeletons and appendages show high levels of integrity, brought into q

248 e from cells with proximal identities in the appendage stump.

249 Ectodermal appendages such as feathers, hair, mammary glands, saliv

250 eriously glide on surfaces in the absence of appendages such as flagella or pili.

251 ding the epidermis and ectodermal associated appendages such as hair, eye, and the mammary gland.

252 contributing to the formation of ectodermal appendages such as teeth, salivary glands and lingual pa

253 Development of ectodermal appendages, such as hair, teeth, sweat glands, sebaceous

254 lity to regulate A/P polarity in traditional appendages, such as legs.

255 mal hyperkeratosis, or abnormalities in skin appendages, such as nail plate dystrophy and structural

256 up from the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with

257 nantly from PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with

258 The PROTECT AF (WATCHMAN Left Atrial Appendage System for Embolic Protection in Patients With

259 ram-positive bacteria, extracellular protein appendages termed pili are necessary for adherence under

260 a component of the basal foot, a centriolar appendage that connects centrioles to the apical cytoske

261 The primary cilium, a sensory appendage that is present in most mammalian cells, plays

262 The test compounds feature a long lipophilic appendage that was shown to mediate biased signaling.

263 Ba)SrtA sortase contains a unique N-terminal appendage that wraps around the body of the protein to c

264 eed is due to constantly beating flagella or appendages that are positioned either anteriorly or post

265 d by having a robust first pair of raptorial appendages that bear well-developed ventral-facing spine

266 a new class of sensors bearing antenna-like appendages that can extend the wavelength of the chiropt

267 Primary cilia are cellular appendages that coordinate diverse sensory and signaling

268 Fimbriae (also known as pili) are appendages that extend up to 2 mum beyond the cell surfa

269 Many motility organelles are complex surface appendages that have evolved a tight, hierarchical regul

270 Conjugative pili are widespread bacterial appendages that play important roles in horizontal gene

271 ates, rays and holocephalans) possess paired appendages that project laterally from their gill arches

272 Fimbriae are protein-based filamentous appendages that protrude from the bacterial cell surface

273 Its highly mobile chin appendage, the Schnauzenorgan, is rich in electrorecepto

274 Left atrial appendage tissue from 33 AF patients and 9 controls was

275 Here, we use the vertebrate appendage to demonstrate how these disciplines can mutua

276 ineage implies the transformation of frontal appendages to another structure in crown-group euarthrop

277 ls on the skin surface and within associated appendages to regulate this orchestrated maturation in t

278 e the role Hox genes play in specifying each appendage type in Parhyale, including the modular nature

279 strates can be sensitive to small changes in appendage use.

280 p of Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stro

281 along the posterior base of the left atrial appendage visualized by selective angiography.

282 f interest via click chemistry, the allyloxy appendage was functionalized with an azide moiety.

283 At the end of the terminal study, the LA appendage was obtained.

284 Optimization of the core and aryl appendages was performed by scanning and matrix librarie

285 y bypass, paired samples of the right atrial appendages were obtained before venous cannulation of th

286 Thirty-five left atrial appendages were obtained during AF surgery.

287 eters of the left atrium and the left atrial appendage which have been shown to be associated with is

288 A is essential for the assembly of subdistal appendages, which anchor cytoplasmic microtubules and pr

289 We show that the bulbous stamen appendages, which are consumed by various species of pas

290 nectivity between the spinal cord and paired appendages, which is crucial for appendage mobility.

291 , combination of the pyrazolo[1,5-a]pyridine appendage with a 5-hydroxy-N-propyl-2-aminotetraline uni

292 ed with dorsal outgrowths to evolve a dorsal appendage with motor control.

293 As the birds seize an appendage with their beaks in order to remove it from th

294 nscript modifications consists of a flexible appendage with three distinct globular domains.

295 ve pairs of walking appendages, opisthosomal appendages with book gills, muscles, and fine setae perm

296 yogenesis that later metamorphose into adult appendages with distinct morphologies.

297 and bicyclic scaffolds with polyhydroxylated appendages with the aim to expand the skeletal diversity

298 CVL was higher in left atrial appendages with thick compared with thin interstitial co

299 l similarity between the pectoral and pelvic appendages within each taxon.

300 First, the appendages work as bellows organs in a unique pollen exp