ライフサイエンスコーパス: appendicular

1 on, deficits in expressive language, ataxia, appendicular action tremors and unique behaviors such as

2 differentiation into bone in the developing appendicular and axial skeletal elements.

3 tion, which results in high bone mass in the appendicular and axial skeleton.

4 ing transgenic mice are dwarfed, with axial, appendicular and craniofacial skeletal hypoplasia.

5 e we asked whether Fmr1-KO mice also display appendicular and oromotor deficits comparable to the ata

6 adult), region-specific (e.g. cranial versus appendicular) and species-specific size and shape.

7 featuring bradykinesia, rigidity (axial > appendicular), and positive pull-test finding.

8 our ileal, two ileocecal, three cecal, three appendicular, and 14 sigmoid colon lesions.

9 nx2-II(-/-)) mice unexpectedly formed axial, appendicular, and craniofacial bones derived from either

10 ts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330)

11 egulates HoxD expression specifically in the appendicular axes of the embryo.

12 Whole-body BIA data suggest an increase in appendicular body cell mass associated with improved ant

13 to normal levels in Ts65Dn mice rescued the appendicular bone abnormalities, suggesting that appropr

14 n though both black women and men had longer appendicular bone lengths relative to stature (p values

15 Whole-body and appendicular bone-free lean mass and fat mass were measu

16 (HSCs) in the endosteum of mesoderm-derived appendicular bones have been extensively studied.

17 Neural crest-derived bones differ from appendicular bones in developmental origin, mode of bone

18 zation of the calvarium, shortened and bowed appendicular bones, trident shaped acetabula and polydac

19 ice develop a low bone mass phenotype in the appendicular but not the axial skeleton compared to the

20 e mutation Ulnaless alters patterning of the appendicular but not the axial skeleton.

21 rogene insertion, previously associated with appendicular chondrodysplasia, also reduces neurocranium

22 racic notum, the other stating that they are appendicular derivations from the lateral body wall.

23 unique animal model that exhibits ataxia and appendicular dystonia without pathological abnormalities

24 implications of this reorganization for non-appendicular exoskeletal structures are lacking, given t

25 Appendicular fat and lean mass demonstrated the stronges

26 The joint associations of appendicular fat and lean mass on HAQ were additive with

27 ppendicular lean mass (-0.7 +/- 0.1 kg), and appendicular fat mass (-2.6 +/- 0.2 kg) each decreased.

28 in the highest versus the lowest quartile of appendicular fat mass (P<0.001), and 0.81 units higher f

29 bone harbors HSCs that function similarly to appendicular HSCs but are deficient in the lymphoid line

30 egative, LSK cells proliferated similarly to appendicular HSCs, and differentiated into all hematopoi

31 d hematopoietic bone marrow in vivo, just as appendicular HSCs.

32 med in 280 patients with symptoms in various appendicular joints by using 5.0-, 7.5-, or 10.0-MHz tra

33 We aimed to test whether LY increases appendicular lean body mass (aLBM) and improves physical

34 opean ancestry) subjects from 25 cohorts for appendicular lean body mass was successful for five sing

35 rphisms in/near VCAN, ADAMTSL3, and IRS1 for appendicular lean body mass.

36 kg), whole-body fat mass (-6.9 +/- 0.5 kg), appendicular lean mass (-0.7 +/- 0.1 kg), and appendicul

37 We evaluated the relation between appendicular lean mass (ALM) and relative leukocyte telo

38 established dietary pattern techniques) with appendicular lean mass (ALM), quadriceps strength (QS),

39 [body mass index (BMI), total fat mass, and appendicular lean mass (aLM)] and C-reactive protein (CR

40 th lower fat mass (in women only) and higher appendicular lean mass (in both sexes, after adjustment

41 greater total body (4.8% and 4.1%) and total appendicular lean mass (LM; 3.0% and 2.1%) compared to A

42 in the lowest versus the highest quartile of appendicular lean mass (P<0.001).

43 composition (including lean body mass [LBM], appendicular lean mass [ALM], and fat mass); objective p

44 Appendicular lean mass also decreased in RDA compared wi

45 protein intake (grams per day) and BMD, ALM, appendicular lean mass normalized for height (ALM/ht(2))

46 Loss of appendicular lean mass was also greater with HF (-419.9

47 Adjusted appendicular lean mass was decreased among the lowest AL

48 Among women with HF, loss of total and appendicular lean mass were also greater than in non-HF

49 after 10 wk of intervention, whole-body and appendicular lean mass were measured by using dual-energ

50 0.43 SD (95% CI: 0.15, 0.72) higher and mean appendicular lean mass-for-total-lean-mass was lower (-0

51 mass, higher PAEE was associated with higher appendicular lean mass.

52 ity risk, possibly attributable to decreased appendicular lean mass.

53 is complicated by obesity and relatively low appendicular lean mass.

54 w SM prediction formulas were developed with appendicular lean soft tissue (ALST) estimates by DXA as

55 A strong link should thus exist between appendicular lean soft tissue (ALST) mass and total-body

56 rajectories for height, WB lean soft tissue, appendicular lean soft tissue, and WB and skeletal site-

57 ysical activity can attenuate the decline in appendicular lean tissue expected over 10 y.

58 protein and changes in total LM and nonbone appendicular LM (aLM) in older, community-dwelling men a

59 and distribution are associated with LM and appendicular LM (aLM), and their 2-y decline, in communi

60 nce, fat mass (FM), fat-free mass (FFM), and appendicular mass by dual-energy X-ray absorptiometry; a

61 CNS, studies usually rely on exoskeletal and appendicular morphology.

62 mployed standard motor tests for balance and appendicular motor coordination, and used a novel long-t

63 the limb bud, but it is essential for normal appendicular muscle formation and for the normal regulat

64 t compared with isocaloric control preserves appendicular muscle mass in obese older adults during a

65 The 13-wk change in appendicular muscle mass, however, was different in the

66 The primary outcome was change in appendicular muscle mass.

67 ecifically to hypaxial muscle, including the appendicular muscle that populates fins and limbs.

68 In addition to expression in embryonic appendicular muscle, slow MyHC 3 is expressed continuous

69 somites to forming hypaxial and specifically appendicular muscle.

70 set point that mimics disuse atrophy in the appendicular muscle.

71 within somitic regions fated to give rise to appendicular muscle.

72 nt in their developmental history to produce appendicular muscle.

73 ol subjects, cachectic patients had reduced (appendicular) muscle mass (-10%), muscle fiber atrophy (

74 es that the embryologic origins of axial and appendicular muscles are distinct, and limb muscle abnor

75 in many vulnerable axial muscles and several appendicular muscles at the disease end stage.

76 dentification of probable homologies between appendicular muscles of sarcopterygian fish and tetrapod

77 propulsive force, tetrapods also rely on the appendicular muscles of the limbs to generate movement.

78 We compared masticatory and appendicular muscles responses to microgravity, using mi

79 can contribute fully to the formation of the appendicular muscles.

80 body wall forms in the tadpole, while limb (appendicular) muscles form during metamorphosis to the a

81 mposition of the anomalocaridid head and its appendicular organization.

82 mal gonocoxopodite was not, suggesting a non-appendicular origin for this structure.

83 o determine whether loss of Nf1 in axial and appendicular osteochondroprogenitors recapitulates the s

84 nearby protein-coding Hox genes, and acts on appendicular patterning at least in part by modulating r

85 of the clavicles, scapulae, metacarpals, and appendicular proportions.

86 ertebrates are composed of two portions: the appendicular region (stylopod, zeugopod and autopod) and

87 e results in severe craniofacial, axial, and appendicular skeletal abnormalities, leading to perinata

88 BmprIB; Bmp7 double mutants exhibit severe appendicular skeletal defects, suggesting that BMPRIB an

89 e of BMPRIB, BMP7 plays an essential role in appendicular skeletal development.

90 nd that Smad7 is required for both axial and appendicular skeletal development.

91 ay an important role in patterning axial and appendicular skeletal elements and the nervous system of

92 ted gap junction component, shared axial and appendicular skeletal malformations with Tbx5(+/Delta) m

93 lay a key role in determination of axial and appendicular skeletal morphology and may be a key compon

94 y mass index (BMI)-specific decile groups of appendicular skeletal muscle index (ASMI; kg/m(2)) and f

95 Sarcopenia was defined as appendicular skeletal muscle mass (kg)/height2 (m2) bein

96 cal activity energy expenditure and elevated appendicular skeletal muscle mass and energy intake in A

97 Aging was inversely associated with total appendicular skeletal muscle mass in older men (r = -0.4

98 ntake may not offset the age-related loss of appendicular skeletal muscle mass in older men.

99 Furthermore, an effect of age on appendicular skeletal muscle mass persisted after standi

100 An effect of age on appendicular skeletal muscle mass persisted after standi

101 n them for the decile values of fat mass and appendicular skeletal muscle mass utilizing the LMS stat

102 Total appendicular skeletal muscle mass was determined by dual

103 An anthropometric equation for predicting appendicular skeletal muscle mass was developed from a r

104 Participants' LBM and appendicular skeletal muscle mass were measured using du

105 roup had lower LBM (beta = -0.75; P = 0.03), appendicular skeletal muscle mass, and grip strength tha

106 d attenuate the age-related decline in total appendicular skeletal muscle mass.

107 11)In-labeled leukocytes in the diagnosis of appendicular skeletal osteomyelitis.

108 In contrast, the appendicular skeletal phenotype of Noggin mutants was un

109 cal analysis showed alterations in axial and appendicular skeletal structure, hindlimb peripheral ner

110 endochondral bone formation during axial and appendicular skeletogenesis.

111 the results are compared with a site in the appendicular skeleton (humerus).

112 terior (AP) patterning in both the axial and appendicular skeleton and acts as a regulator of Hox gen

113 abuse include separate frontal views of the appendicular skeleton and frontal and lateral views of t

114 tations in Hoxa13 cause malformations of the appendicular skeleton and genitourinary tract, including

115 e all characterised by the shortening of the appendicular skeleton and loss or abnormal development o

116 lements arise from the paraxial somites, the appendicular skeleton and sternum arise from the somatic

117 Long bones of the appendicular skeleton are formed from a cartilage templa

118 The long bones of the vertebrate appendicular skeleton arise from initially continuous co

119 uced an Lrp5 mutation in cells that form the appendicular skeleton but not in cells that form the axi

120 The axial and appendicular skeleton displayed malformations and in par

121 function Foxp mutations had gross defects in appendicular skeleton formation.

122 ing an understanding of the way in which the appendicular skeleton has evolved to provide the scaffol

123 In general, bone strength in the appendicular skeleton is compromised because of thinner

124 We observed an increase in the axial and appendicular skeleton lengths, and improvements in dwarf

125 However, the axial and appendicular skeleton of Cx43-null animals were essentia

126 s condensations (PCCs) in both the axial and appendicular skeleton of mouse embryos and in committed

127 The axial and appendicular skeleton showed no sign of lesions.

128 ion of mammalian stanniocalcin (STC1) in the appendicular skeleton suggests its involvement in the re

129 IFT is essential for normal formation of the appendicular skeleton through disruption of multiple sig

130 The vertebral column, ribs, and appendicular skeleton were all affected in these embryos

131 s, widespread metaphyseal involvement of the appendicular skeleton, and carpal ossification delay.

132 ns of first and second branchial arches, the appendicular skeleton, and the dermal papillae of the vi

133 thin mesenchymal precursors of the axial and appendicular skeleton, before chondrogenesis occurs.

134 limb, where they serve as primordia for the appendicular skeleton, is preceded by the appearance of

135 a hypomorph allele in the development of the appendicular skeleton, kidneys, and female reproductive

136 ween these factors during development of the appendicular skeleton, mice were produced with various c

137 In the axial and appendicular skeleton, post-natal deficits in Pth/Pthrp

138 FGFR3(K650E) expression was directed to the appendicular skeleton, we show that the mutant receptor

139 volved in global patterning of the axial and appendicular skeleton.

140 s with respect to formation of the axial and appendicular skeleton.

141 despread patterning defects of the axial and appendicular skeleton.

142 erichondrium of the craniofacial, axial, and appendicular skeleton.

143 ed form of bone loss affecting the axial and appendicular skeleton.

144 t defects that are largely restricted to the appendicular skeleton.

145 iple defects that include bony fusion of the appendicular skeleton.

146 or the development and maintenance of the DS appendicular skeleton.

147 vitamin in the development of the axial and appendicular skeleton.

148 Here we have examined the appendicular skeletons of Akp2-/-, Enpp1-/-, and [Akp2-/

149 Improvements to the axial and appendicular skeletons were noticeable after 10 days of

150 ing year 1 (-1.4 +/- 0.2 kg; P < 0.001) with appendicular SM regained during year 2.

151 Appendicular SM was regained during the second year wher

152 movements, and axial hypotonia with variable appendicular spasticity.

153 unctionally integrated postcranial axial and appendicular systems derived from two distinct populatio