ライフサイエンスコーパス: approach

1 regions (long read support based validation approach).

2 uses a pioneering hybrid quasi-single model approach.

3 y of periodontitis through a deep-sequencing approach.

4 tumors is emerging as an important clinical approach.

5 otic pathways may be a promising therapeutic approach.

6 ts with those from the conventional ITS2-PCR approach.

7 requirement for further development of this approach.

8 lementation of a powerful reverse regression approach.

9 related problems can be also studied by this approach.

10 tions using an RNA interference (RNAi)-based approach.

11 ing both a distance and a volumetric overlap approach.

12 features", using a context-driven annotation approach.

13 treated according to the "one-size-fits-all" approach.

14 carbon nitride, was fabricated by a one-step approach.

15 of targeting BCL6 as a potential therapeutic approach.

16 eed to be considered in deciding the optimal approach.

17 o a traditional backwards variable selection approach.

18 zation, when compared to the other evaluated approaches.

19 eadout mechanisms, among them optomechanical approaches.

20 ing the importance of mathematical modelling approaches.

21 hanisms have been poorly explored by genetic approaches.

22 in LSC survival and develop new therapeutic approaches.

23 of electrochemical DNA methylation detection approaches.

24 operties to overcome limitations of previous approaches.

25 nt resources to incorporate both stewardship approaches.

26 evolution and in modern HSC transplantation approaches.

27 thways in AKI may identify novel therapeutic approaches.

28 lude the use of standard bottom-up proteomic approaches.

29 CTLA-4 pathway identified by gene-sequencing approaches.

30 rience be transferred to further theranostic approaches?

31 Here we use magnetic fields approaching 100 Tesla to reveal the extent of the spin c

32 al-censored survival and binomial regression approaches a multi-model framework was implemented to es

33 In this study, we introduce a new approach, a combination of EEG and NIRS, to detect drive

34 Our novel experimental approach accurately models human NBL and establishes a n

35 We computationally illustrate that our approach achieves errors of roughly 5% in predicting the

36 ce in predictions between the two analytical approaches across all samples analyzed, with SERS demons

37 such as oncology or rheumatology, we have to approach AD in a more differentiated way (ie, to dissect

38 The approach added saccharide units to insulin to create ins

39 Generally, our approach allows to assess the danger of self-sustained e

40 This approach allows us to predefine the mechanical and physi

41 rmediates, an intermolecular version of this approach also afforded (Z)-alpha,beta-unsaturated amino

42 This approach also allowed us to study the properties of dist

43 This approach also performs sequence assembly across multiple

44 More and more of these approaches also enable the monitoring of possible key in

45 Using this approach, an optimized macrocyclic peptide inhibitor (HL

46 In one such approach, an understanding of the distal and geometric r

47 To this end, using an empirical approach and a simple conceptual model, we propose a fra

48 ons, Assessment, Development, and Evaluation approach and summarized the results in evidence profiles

49 ght the key contributions of these synthetic approaches and how the development of novel Ub-based rea

50 Using acute inactivation approaches and live-cell imaging in Drosophila embryos,

51 Our study permits a comparison of the two approaches, and the data support the further development

52 standardized, straightforward and efficient approach applicable in routine analysis of flavonoids co

53 The only parameters in the approach are the weights of the neural network, which ar

54 and differentiate tissue types, but existing approaches are both CPU and memory-intensive, limiting t

55 Our experimental and analytical approaches are important alternatives and complements to

56 These approaches are likely to be of value in interpreting the

57 Here, we posit that open-innovation approaches are more successful when they establish a rel

58 s probably inevitable, and novel therapeutic approaches are needed to target dormant tumors.

59 Automated approaches are preferable for this, primarily because of

60 emphasizes the diagnostic potential of this approach as a screening technique for non-Hodgkin lympho

61 theoretical method, and (ii) to validate our approach as function of temperature and of pressure, as

62 metadata and GEO data using both a heuristic approach as well as machine learning.

63 Therefore, longitudinal studies and big-data approaches assessing sleep dynamics are lacking.

64 Here, starting with a medicinal chemistry approach, Baker et al. generate an imidazopyridine that

65 is barrier, we developed a synthetic-biology approach based on a technique known as codon shuffling.

66 ons in graphene using a multiscale modelling approach based on combining the phase field crystal appr

67 nd performed resistome analysis, an unbiased approach based on RNA sequencing of resistant subclones,

68 overall goal is to develop machine-learning approaches based on genomics and other relevant accessib

69 We have improved the original approach by developing long-read ChIA-PET, in which the

70 Furthermore, our approach can be applied beyond Immunology, and serve as

71 Our approach can be readily adapted to other imaging modalit

72 Accordingly, we claim that our approach can be used as a future guide to investigate th

73 The results demonstrate that this approach can generate confident copy number measurements

74 This approach can potentially be developed into a single-mole

75 We believe that these data-driven approaches can complement the traditional method of clos

76 amplification (LAMP) is a DNA amplification approach characterized by high sensitivity and specifici

77 We illustrate how a systems pharmacology approach combining experimental and computational method

78 nd lack of cost data from other case-finding approaches commonly used in India.

79 This new approach complements available prodrugs/donors that dire

80 composition of live cells using a label-free approach, confocal Raman microspectroscopy.

81 er genes, we propose a novel consensus-based approach, ConsensusDriver, which significantly improves

82 Further development of this approach could lead to fast and automated purification o

83 tentially suppress virus proliferation, this approach could offer a new strategy for the development

84 cer Cell, Chen et al. describe complementary approaches demonstrating that MLL1 is dispensable for ML

85 In this Perspective, we present new approaches directed at the design of efficient entry inh

86 Our approach emphasizes the commonly overlooked difference b

87 This approach enabled us to diagnose an issue with TXS solubi

88 combining observation scales and analytical approaches enabled to quantify SM degradation and to ide

89 Our approach enables researchers to unlock phenotypic inform

90 Moreover, this approach enables the accurate determination of the relat

91 This safe and effective approach expands treatment options and should be conside

92 aim to provide an integrated overview of the approaches explored for the modulation of 14-3-3 PPIs an

93 ggest that PXR antagonists may provide a new approach for ALD therapy.

94 s that could facilitate a precision medicine approach for ARDS.

95 irotherapy is an effective immunotherapeutic approach for cancer treatment via a multistep process in

96 ore developed InFlo, a novel systems biology approach for characterizing complex biological processes

97 tis) has been demonstrated to be a promising approach for diabetes reversal in NOD mice.

98 The sealed vessel method is a new approach for fast cleavage of PCB from phycocyanin and g

99 6 antagonists may be a promising therapeutic approach for Hh-associated medulloblastoma in humans.

100 otronic effect is invented as an alternative approach for performance enhancement of self-powered PDs

101 rnian bird surveys and a detectability-based approach for quantifying phenological signal, we show th

102 RNA-mediated interference has been one major approach for sequence-specific regulation of gene expres

103 NA sensor has potential to be an alternative approach for simple, rapid, sensitive, and selective DNA

104 re of the epigenome that leads to a powerful approach for studying its role in disease and aging.

105 e biology and illustrate a fundamentally new approach for systematic in vivo investigations of cell m

106 Here we introduce a protecting-group-free approach for the alpha-functionalization of cyclic secon

107 alkynyl nucleophiles represent an attractive approach for the incorporation of alkynyl moieties into

108 niques have attracted interest as a photonic approach for the selective inactivation of virus contami

109 irst time, demonstrating the utility of this approach for the synthesis of heterofunctional glycomacr

110 of non-viral TUS-based hSef-b gene delivery approach for the treatment of prostate cancer tumors, an

111 development of this multifunctional vaccine approach for the treatment of synucleinopathies, such as

112 unately, there is no effective pharmacologic approach for treating or preventing AKI.

113 a support development of eCB-based treatment approaches for mood and anxiety disorders and suggest a

114 In practice, the regular approaches for QTL mapping analysis may be adopted for m

115 er the predictions made by these mechanistic approaches for the stratification and development of new

116 ing a Lab-on-a-Printed Circuit Board (LoPCB) approach, for TB diagnosis based on cytokine detection.

117 at tackle this problem from a diverse set of approaches, from anatomy to electrophysiology to computa

118 Sample weighting approaches had little impact on field-estimated trait re

119 One approach has been to make use of frustrated growth of th

120 This integrated approach has demonstrated the significant role of the me

121 commonly measured in solution; however, this approach has several disadvantages that can reduce sensi

122 ific examples where the application of these approaches has uncovered effects of gene-environment int

123 All approaches have significant drawbacks with respect to st

124 The approach identified awareness of NTP's work on CrVI by e

125 effects may offer potential as a therapeutic approach in AD.

126 This study used a phosphoproteomic approach in CRF-overexpressing (CRF-OE) mice to test the

127 rovide a new target for an anti-inflammatory approach in diabetic vascular disease.

128 its kind theranostic that may serve as a new approach in our growing therapeutic toolbox.

129 irE2 inside plant cells by using a split-GFP approach in real time.

130 as severity prediction far exceeds any other approach in this field and is a strong indicator that th

131 erlines the potential role of an inter-omics approach in understanding the metabolic pathways involve

132 We cover applications of optobiological approaches in the study of cellular and organismal funct

133 We suggest a mainstreaming approach including greater integration of fungal disease

134 nstrained projection) to two non-constrained approaches including CIBERSORT and a method based on rob

135 een identified using biochemical and genetic approaches including specific knockdowns of genes of int

136 he either an open approach or a laparoscopic approach (including procedures converted to open).

137 part may be due to different methodological approaches, including use of either peptide:N-glycosidas

138 A newer approach independent of additional information is to dir

139 The approach integrates cellular behaviors via agent-based m

140 This unconventional biosensing approach involves measuring the change in sample viscosi

141 , we report the use of an in vitro evolution approach involving systematic evolution of ligands by ex

142 Our approach is based on a similar idea to the sequential Ma

143 accuracy, robustness, and reliability of the approach is demonstrated in an application to the phycob

144 An alternative approach is digital holography where wave-phase informat

145 This approach is environmentally friendly, fully translatable

146 One approach is to develop radiosensitizing compounds.

147 algorithms, but the predictive power of this approach is unclear.

148 This approach is validated by quantitative measurements of en

149 The dual-element C-H isotope approach (LambdaC-H = Deltadelta(2)H/Deltadelta(13)C app

150 This approach may be amenable to numerous enzymes and to engi

151 s been identified, the (1)H NMR chemometrics approach may contribute in the choice of the temperature

152 Such an approach may find use in label-free selection of cells f

153 The nasal area may assist with detection of approaching objects from behind, potentially representin

154 This approach obviates conventional relative quantification u

155 Here, we present an approach of cell-free protein synthesis (CFPS) that prov

156 was to determine the potential and practical approaches of using this sensor for non-destructive diag

157 The present approach offers a possible route to detecting interfacia

158 Using a forward genetics approach, one nonsense and four missense Gmsacpd-c mutan

159 Our design approach opens new avenues for optically controlling enz

160 es were used to determine the either an open approach or a laparoscopic approach (including procedure

161 ases are lacking, and the emerging tools and approaches outlined here offer researchers studying comp

162 Such approaches promise to improve drug specificity by reduci

163 Trait-based approaches provide a useful framework to investigate pla

164 Integrated approaches provided a better perspective for developing

165 Moreover, this single-cell approach provides a better understanding of how prostate

166 Our approach provides a clean gas-phase synthesis of this hi

167 rk with information derived from TF-centered approaches provides a foundation for a phenolics GRN cha

168 This effect is realized in the approach referred to as "trimethylation enhancement usin

169 Our approach remembers old tasks by selectively slowing down

170 Based on these results, our approach represents a promising biotechnological tool fo

171 opment and application of precision oncology approaches require robust elucidation of the genomic lan

172 l course of photoreaction due to the orbital approaches required for photochemical reactivity.

173 hototransduction genes by using a variety of approaches (restricted branch/branch-site models and unr

174 Our approach shows a relationship between choice of tag and

175 A sectors approach shows good screening test characteristics for t

176 a population-level microsatellite profiling approach, SID (Saccharomyces cerevisiae IDentifier), to

177 insights but also a plethora of experimental approaches, sometimes reaching conflicting or poorly sup

178 We describe two new complementary approaches - stable isotope probing coupled with nanosca

179 rs could be obtained by a nonstereoselective approach starting from 2'-F U.

180 Recently, many new approaches, study designs, and statistical and analytica

181 However, this method was the only approach successful in the classification of samples, an

182 The approach taken in this work has shown that it is possibl

183 The approach takes advantage of a nonenzymatic and chemosele

184 A combined approach targeting HDAC1/HDAC2 and MYC may present a nov

185 ic overlap between AEA and 2-AG augmentation approaches than was previously appreciated.

186 atory-based risk factors is equivalent to an approach that additionally incorporates adult lipid meas

187 f the underlying disease, represents a valid approach that can improve the pulmonary status and preve

188 might be useful to consider a multifactorial approach that highlights building trust in vaccinators,

189 ariates for multiphenotype studies (CMS), an approach that improves power when correlated phenotypes

190 We demonstrate a travelling source approach that overcomes the sub-luminal propagation limi

191 We aimed to develop a methodical approach that would yield a broad assessment of National

192 in gastrointestinal cancer risk, as well as approaches that apply precision medicine methods to popu

193 is article, we summarize several statistical approaches that can be used to test for GxE in a genome-

194 e delivery of ecosystem services, integrated approaches that incorporate multiple drivers of change a

195 to be combined with additional complementary approaches that prevent replenishment or repopulation of

196 ant alternatives and complements to standard approaches that use segmented speech and block designs,

197 tence of g when analyzing data using a mixed approach, that is, when comparing individuals of differe

198 Within our approach the solution of the computation is encoded in t

199 steering and reorientation of the molecules approaching the surface, activating the O-H bonds and in

200 Approaching the transition, DeltaPsi and ROS increased,

201 As compared to existing approaches, this provides the possibility to reveal high

202 e sectors and demonstrate the utility of the approach through a case study.

203 e we demonstrate a new high-yielding modular approach to a broad range of trimeric and hexameric S- a

204 We applied our spatial approach to a set of images from patients with malarial

205 As an example, we apply our approach to analyze the concentration dependence of the

206 As a fundamentally new approach to bioconjugation this methodology provides a b

207 Here we adopt this powerful approach to breast cancer and analyse 515 cells from 11

208 report an iridium-catalysed tyrosinase-like approach to catechols, employing an oxyacetamide-directe

209 This work provides a novel biospectroscopy approach to characterize the chemotaxis-related alkane b

210 Herein we show a versatile approach to control the buckling of individual domains a

211 the onset of AD dementia can be a promising approach to decrease the incidence of AD.

212 This work demonstrates a viable approach to develop lithium-sulfur batteries with practi

213 The traditional approach to diagnosis emphasises the importance of thoro

214 Using a conditional mouse genetic approach to disable nonredundant subunits of mTORC1, mTO

215 d guide best practices for a genetics-driven approach to early intervention in at-risk relatives.

216 A standard approach to eliminating confinement errors in bacterial

217 A) represent a powerful functional proteomic approach to elucidate cancer-related molecular mechanism

218 is the first demonstration of an integrated approach to elucidate how heterogeneity at the transcrip

219 A photodegradable material-based approach to generate endothelialized 3D vascular network

220 Here, we present a transformational approach to genome engineering of herpes simplex virus t

221 ticipate that the suggested pull and release approach to graphene folding may find applications in th

222 model-independent, physical/observable-based approach to identify structural properties of quiescent

223 pression dynamics with a reverse engineering approach to infer data-driven dynamic network models of

224 Here, we used a mass spectrometry (MS)-based approach to map the complete glycosylation profile at ev

225 e results demonstrate the feasibility of our approach to monitor the position and dynamics of both re

226 The reaction provides a straightforward approach to pharmaceutically and synthetically useful 2-

227 Our results challenge the trait-based approach to predicting ecosystem function by demonstrati

228 permanent porosity, and thus opens up a new approach to prepare porous carbon liquids.

229 t-centered, individualized, and parsimonious approach to quality assessment needs to be maintained to

230 We develop a pore recognition approach to quantify similarity of pore structures and c

231 erall, our results illustrate a quantitative approach to relate fluorescence signals to malignant tis

232 tecture of the D-Wave machine, initiating an approach to reversible classical computation based on st

233 In our novel, computationally tractable approach to RNA-ligand kinetics, we overcome the two mai

234 ntegrated photonic chip with a circuit-based approach to simulate the dynamics of a spin chain and ma

235 Importantly, a competition-based approach to specifically mislocalize APC-dependent RNAs

236 Applying this labeling approach to structured illumination microscopy resulted

237 We applied this approach to systematically characterize MHC ligands from

238 We designed an approach to target an extracellular matrix protein, the

239 A new approach to the analysis of Cu, Fe, Mn and Zn in flaxsee

240 We advocate this more mechanistic approach to the categorization of ACS to provide a frame

241 DB2CD has been created as an empirical-based approach to the generation of protein CD spectra from at

242 In the present work, we apply the PFM approach to the study of a challenging set of sequences-

243 kinetic resolution process offers a general approach to the synthesis of enantioenriched atropisomer

244 Such a strategy may offer an important new approach to the treatment of patients awaiting LT which

245 hat targeting this molecule could be a novel approach to treat allergic asthma.

246 zed data collection, adopting a connectomics approach to understanding brain network architecture, em

247 In this paper, we propose a new approach to use Parylene C as a versatile template for p

248 Different approaches to analysing the botanical origin of tannins

249 ria could be a useful strategy to design new approaches to antibacterial therapy.

250 Here we combine in silico and in vitro approaches to characterize the SOS transcriptional respo

251 man proteome microarrays, and we expect such approaches to contribute substantially to the understand

252 itorial, Sarah Stock and Jenny Myers discuss approaches to fetal and neonatal growth assessment.

253 a breath-taking pace and are revolutionizing approaches to gain a better understanding of human disea

254 ous enzymes and to engineering and screening approaches to identify activators and blockers with stro

255 Using multiple labeling approaches to identify pathways and their postsynaptic s

256 ndothelial cells may lead to new therapeutic approaches to improve blood vessel regeneration and incr

257 We investigate several approaches to interpret the phase images including signa

258 ing techniques enable a radically new set of approaches to limit evolution.

259 The present study considers two different approaches to obtain increased sensitivity to transient

260 ecision making and may assist the advance of approaches to prevent premature diagnostic closure.

261 Rational approaches to the case management of cholera with oral a

262 defensive (to avoid predatory detection) and approach (to obtain food) behavior.

263 Our "ex-cell" approach toward the electrosynthesis of benzoxazoles is

264 However, these approaches typically demand extensive sectioning and rec

265 Depending on the approach used to adjust for inflammation (CRP plus AGP),

266 Depending on the approach used to adjust for inflammation (CRP+AGP), the

267 We illustrate the approach using the example of HeLa cells expressing paxi

268 vo have been published, and we validated our approach using this control by confirming 175 of 323 ult

269 Furthermore, this approach was able to produce a targeted autosome loss in

270 us gland size, indicating that this pro-drug approach was critical to obtain the desired activity in

271 This approach was informed by the development of a pseudo fir

272 Firstly, validation of the approach was performed by correlating conjugated diene c

273 A metagenomic approach was taken complemented by detection of N2 O rel

274 Through a rational design approach we discovered a highly selective and potent BTK

275 Using a conditional targeting approach, we ablated the major CLP gene Irf6 only in the

276 Using an integrative systems biology approach, we also revealed that M2 polarization and chol

277 Using a crystal scanning approach, we determine the high-resolution structure of

278 hosphothreonine in cells with this selection approach, we discover a phosphothreonyl-tRNA synthetase-

279 Instead of taking this approach, we introduce versatility, V, as a novel metric

280 By multiplexing this approach, we investigate the unique transhesive profiles

281 Using a translational approach, we then demonstrate that human induced Treg ce

282 Using mass spectrometry approaches, we identified 16 VTPs of the CyHV-3 FL strai

283 By harnessing multiomics approaches, we may gain valuable insights into their pot

284 Using a combination of genetic mapping approaches, we show that the white recessive allele is d

285 Here, we use a different approach: we propose a model for language dynamics based

286 Neuropharmacological and Homer2 knockdown approaches were also used in C57BL/6J mice to confirm th

287 e results found pointed out that both SW-ASV approaches were suitable and easy-to-use method to monit

288 PGE2-G, we performed a subtractive screening approach where mRNA from PGE2-G response-positive and -n

289 , biologically motivated, Bayesian multitask approach, which explicitly models gene-centric dependenc

290 The approach, which is the first demonstration of applicabil

291 Our flexible Bayesian approach will be especially useful to improve cross-cult

292 Even if successful, however, these approaches will need to be combined with additional comp

293 Here, we combined a nanoscale imaging approach with advanced image analysis to detect individu

294 h based on combining the phase field crystal approach with classical molecular dynamics simulations a

295 ere we used a more comprehensive mutagenesis approach with the goal of identifying trimer variants wi

296 combine the desynchronizing delayed feedback approach with the HF DBS technique.

297 mutualism using theoretical and experimental approaches with a synthetic anaerobic coculture pairing

298 In addition to conventional approaches with alkyl halides or sulfonates as alkylatin

299 We combined forward and reverse genetic approaches with chromatin immunoprecipitation to identif

300 A more fiscally prudent approach would have been built upon more successful exis