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1 ents who had the option of using at least one fully active, approved antiretroviral drug in at least one but no more than
2   On August 16, 2019, the U.S. Food and Drug Administration approved expanding the indication for transcatheter aortic va
3 ination with other existing US Food and Drug Administration-approved anti-cancer modalities.
4  termed JAK inhibitors, are US Food and Drug Administration-approved in a few autoimmune/inflammatory disorders and are b
5 on, including that for the now Food and Drug Administration-approved peanut OIT product Palforzia (Aimmune Therapeutics,
6           To date, there is no Food and Drug Administration-approved targeted therapy for advanced MCC.
7 reakpoint presumes that AZI (1-g single dose) is used in an approved regimen that includes an additional antimicrobial ag
8 nology, hundreds of biotherapeutics have been developed and approved by the US Food and Drug Administration (FDA) for hum
9 e is currently still only one therapeutic anti-IgE antibody approved for the treatment of allergic conditions.
10 e currently tested in clinical trials, and none of them are approved by health agencies.
11 ake of SSBs.The Health Workers Cohort Study (HWCS) has been approved by the Institutional Review Board of the Mexican Soc
12  is a noninvasive brain stimulation treatment that has been approved by the U.S. Food and Drug Administration for treatme
13                                       Although ISA has been approved for treatment of invasive Aspergillus and mucormycos
14 DA Green Book is a list of all drug products that have been approved by the FDA for use in veterinary medicine.
15                                   The most common biomarker approved by the FDA (United States Food and Drug Administrati
16 s and 252 controls) according to institutional review board-approved protocols and shipped to a centralized biorepository
17  prostate cancer taken prior to starting a standard-of-care approved therapy.
18 pare well with the profiles of the corresponding clinically approved ADC Kadcyla.
19  voltage-gated potassium channels (K(V)1 family) clinically approved for the symptomatic treatment of patients with multi
20                                     Furthermore, clinically approved PCSK9-neutralizing antibodies synergize with anti-PD
21                                 Here, we use the clinically approved MEK inhibitor Trametinib to investigate its potentia
22 ectively registered on January 12th, 2018; Ethics Committee approved the study (ID: 1.790.088) on October 25th, 2016.
23                                     The proportion of drugs approved with an Orphan Drug Act designation increased from 1
24 mended phase 2 dose (RP2D, primary outcome) is the FDA/EMEA approved dose of gemcitabine-nab-paclitaxel along-with ATRA (
25 tor of the mutant isocitrate dehydrogenase 1 (IDH1) enzyme, approved for treatment of IDH1-mutant (mIDH1) acute myeloid l
26                              Between 1997 and 2018, the FDA approved opioids on the basis of pivotal trials of short or i
27 s.IMPORTANCE To date, no Food and Drug Administration (FDA)-approved vaccines are available to combat hemorrhagic fever c
28                     We used HeLa cells and screened 231 FDA-approved oncology and natural substance drugs included in two
29                         Here, we found that olaparib, a FDA-approved PARP inhibitor, could enhance the cytotoxicity in HC
30                                  Disulfiram (DSF) is an FDA-approved drug that has been repurposed for cancer treatment.
31                                 Fingolimod (FTY720), an FDA-approved immunomodulatory drug for treating multiple sclerosi
32 ay was confirmed in human psoriasis using vorapaxar, an FDA-approved PAR1 antagonist, on explanted lesional skin from pat
33 sting of the antibiotic ciprofloxacin hydrochloride and FDA-approved polymers are fabricated.
34 the in vivo efficacy of auranofin (rheumatoid arthritis FDA-approved drug) in a CDI mouse model and establish an adequate
35 d by design of experiments (DOEs) using three different FDA-approved human inhaler devices followed by interaction parame
36 intervention points that can be addressed with existing FDA-approved pharmaceuticals.
37                                     Currently, all four FDA-approved HDAC-targeting drugs are nonselective, pan-HDAC inhi
38                                 Currently, there are no FDA-approved vaccines or therapeutics available to combat VEEV in
39  p110alpha-selective inhibitors, including the recently FDA-approved alpelisib.
40 f Trpm7 and inhibition of TRPM7 channel activity by the FDA-approved drug FTY720 increased the sensitivity of T cells to
41                          Importantly, we identified two FDA-approved drugs able to ameliorate these phenotypes.
42 onal transarterial chemoembolization (cTACE) is a guideline-approved image-guided therapy option for liver cancer using t
43 oncology therapeutics, with eight ADCs and two immunotoxins approved for clinical use.
44                                                          No approved treatments exist for age-related cognitive decline.
45           CHIKV causes explosive outbreaks but there are no approved therapies to treat or prevent CHIKV infection.
46                                                 There is no approved treatment for HMPV and only one prophylactic treatme
47  (EoE) is an allergen-mediated inflammatory disease with no approved treatment in the United States.
48                            Adalimumab is the only treatment approved by either the European Medicines Agency or the U.S.
49 indings have led to the initiation of clinical trials using approved drugs that target the generation (ACEIs) and actions
50                                Baloxavir marboxil (BXM) was approved in 2018 for treating influenza A and B virus infecti