ライフサイエンスコーパス: approximate @-fold

1 n, we present a fast heuristic algorithm for approximating energy barriers encountered during folding

2 between being able or unable to determine an approximate global fold.

3 ncipal increases in trypsin and chymotrypsin approximated to 250-fold.

4 dominant negative Rab5 (S34N) resulted in an approximate 2-fold accumulation of KCa2.3 at the plasma

5 metabolic syndrome to diabetes) conferred an approximate 2-fold adjusted risk of death (HR 2.01, 95%

6 he in vitro data allowed us to calculate the approximate cellular concentrations of the folding and d

7 ra at the temperature extremes establish the approximate chemical shifts for folded and unfolded form

8 Each lobe has internal approximate pseudo 2-fold and pseudo 3-fold symmetry axe

9 The gain in mass sensitivity is approximate up to 17-fold, and the adequate spectral res

10 f six helices related to the other set by an approximate internal two-fold axis.

11 We show that this laser enables an approximate 4-fold decrease in fabrication times for pro

12 This is predominantly the result of an approximate 5-fold decrease in kcat.

13 ent of Met(8) and Leu(12) by Ala resulted in approximate 20- and 55-fold decreases of inhibitor poten

14 rolysis of these same substrates, wherein an approximate 10(5)-fold difference in rates was measured,

15 ine the specificity of tRNA selection, by an approximate 100-fold difference in kcat.

16 e chain reaction of cerebellar mRNA, were an approximate 10-fold down-regulation of pituitary tumour-

17 unken cells exhibit DNA fragmentation and an approximate 4-fold elevation of caspase-3-like activity.

18 most potent of these congeners possessed an approximate 5-fold enhancement of the activity of colchi

19 P-transgenic reporter strain demonstrated an approximate 20-fold enrichment of ILK-competent cells, s

20 An approximate 2000-fold enrichment of FLAG-tagged TFIIH an

21 cell population, for 10 days resulted in an approximate 8-fold expansion of repopulating HSCs.

22 molecular weight RNA binds histones with an approximate 100-fold greater affinity relative to DNA wh

23 ver, hexon-modified Ad5 vectors displayed an approximate 10-fold growth defect in complementing cells

24 This represents an approximate 60-fold growth for literature-based model nu

25 usceptible apoE(-/-) background displayed an approximate 4-fold higher atherosclerotic lesion area th

26 ed ART, changes that were associated with an approximate 4-fold higher odds of recurrent malaria by d

27 on of both strands in vitro, resulting in an approximate 2-fold improvement in potency.

28 fold increase in catalytic efficiency and an approximate 1,000-fold increase in the overall turnover

29 entration and hyperosmolarity resulted in an approximate 10- to 15-fold increase in penetration of HT

30 Treatment with TNF alone produced an approximate 110-fold increase in total TF expression, wh

31 y joined via a flexible linker, there was an approximate 18-20-fold increase in the affinity of the p

32 lavage fluid (BALF) analysis demonstrated an approximate 18-fold increase in Muc5ac protein, which fo

33 utions; it was a loss of efficiency, with an approximate 2- to 5-fold increase in the cost of doing s

34 rhGGF2 (30 ng/ml) provoked an approximate 2-fold increase in embryonic cardiac myocyte

35 ration assay documents that CT-1 provokes an approximate 2-fold increase in embryonic cardiac myocyte

36 In study 1, there was an approximate 2-fold increase in muscle insulin sensitivit

37 Cognate CD4(+) T cell help results in an approximate 2-fold increase in the frequency of secondar

38 posure to lyso-PC (25 microM) showed only an approximate 2.6-fold increase.

39 293 cells with Stim1 and Orai1 results in an approximate 20-fold increase in store-operated Ca(2+) en

40 GF- or KDR-selective variants resulted in an approximate 250-fold increase in TF expression.

41 ports, we found that thapsigargin induced an approximate 3-fold increase in adenylyl cyclase activity

42 both gemcitabine-resistant cell lines had an approximate 3-fold increase in p53R2 protein.

43 This hormone treatment also stimulated an approximate 3-fold increase in the phosphorylation of th

44 in VL-CDR3 and four in VH-CDR3) and gave an approximate 30-fold increase in potency in a cell-based

45 plasia or colon cancer is associated with an approximate 4- and 25-fold increase in risk, respectivel

46 s a 5' --> 3'-exoribonuclease, results in an approximate 4-fold increase in OLE1 mRNA half-life in th

47 inding (K(i) = 0.7 +/- 0.3 microM) causes an approximate 4-fold increase in the K(m)(app) (alpha = 4.

48 In addition, there was an approximate 5-fold increase in IBD risk for persons with

49 ized for the highest log K(OW) POPs, with an approximate 5-fold increase in lipid equivalents concent

50 getable oils consumed and, in particular, an approximate 5.5-fold increase in canola oil use.

51 ntaining vesicle trafficking demonstrated an approximate 7-fold increase in the half-time for plasma

52 r KDR receptor-selective variants induced an approximate 7-fold increase in total TF expression.

53 he Hct from approximately 50% to 30%, and an approximate 8- to 10-fold increase in the reticulocyte c

54 removal of doxycycline for 4 days caused an approximate 8-fold increase in the amount of OGG1 protei

55 ustering of agreement indices resulted in an approximate four-fold increase in the variance of the es

56 tids within a few hours after UV, we show an approximate three-fold increase in recombinants in the T

57 anxiety or depressive disorders predicted an approximate 2- to 3-fold increased risk for adulthood an

58 The approximate 3-fold increased risk of death for higher-ri

59 the Beaver Dam Offspring Study, there was an approximate 4-fold increased age-adjusted prevalence of

60 tion between hypothyroidism and HCC, with an approximate two-fold to three-fold increased risk of HCC

61 tive D/OK and D/660 antiserum found up to an approximate 10-fold loss in cross-reactivity against het

62 The approximate 2-fold of the Fc was independent of that rel

63 ut one still wants to obtain knowledge about approximate topological folding of RNA.

64 In permanently transfected cells with approximate 2-fold overexpression of GPx-1, we found tha

65 This is accomplished by approximating the multidimensional folding process as st

66 In the approximate 30- to 100-fold range of template input abov

67 ylenediamine, and dimethoxyethane--reveal an approximate 40-fold range of rates.

68 f the virus particles generated, we found an approximate 10-fold reduction in the amount of viral DNA

69 product analogues exhibited a corresponding approximate 3-5-fold reduction in cytotoxic activity [L1

70 ccurately but the data obtained indicated an approximate 400-fold reduction in k(cat).

71 ars to be related to the middle domain by an approximate 2-fold rotational axis, thus suggesting TcaB

72 As a result, an approximate 10-fold shift in the K0.5 values for calcium

73 ess, transition state theory can be a useful approximate predictor of cooperative folding speed, beca

74 ation of parotid BK channels, it produced an approximate 2-fold speeding of the channel-gating kineti

75 out symmetry imposition yielded a model with approximate 2-fold symmetrical features.

76 The two copies of the motif are related by approximate 2-fold symmetry and may form a bidentate DNA

77 alpha) subunits of each show either exact or approximate 4-fold symmetry and share a similar transmem

78 domains that form a bi-lobed structure with approximate pseudo 2-fold symmetry.

79 al 4 bp helix, and the overall structure has approximate two-fold symmetry, which makes it well-suite

80 copy revealed an anchor-shaped particle with approximate two-fold symmetry.

81 single copy of PACAP increased MB incidence approximate 2.5-fold, to 66%, thereby demonstrating that

82 ry tumour-transforming gene-1 (pttg1) and an approximate 5-fold up-regulation of a structural homolog

83 There was an approximate 6-fold variation in values for IMGU in this