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1 e PM unless they are coexpressed with a PIP2 aquaporin.
2 w range of plants as a full clade within the aquaporins.
3 ling and osmolarity translated via different aquaporins.
4 or the involvement of water channels, called aquaporins.
5 cross the membranes of cells expressing both aquaporins.
6 the Tonoplast Intrinsic Protein subfamily of aquaporins.
7 Zea maize Plasma Membrane Intrinsic Protein aquaporins.
8 fferent transporters and channels, including aquaporins.
9 n of influx and efflux suggests mediation by aquaporins.
10 de metabolism, cuticle proteins, opsins, and aquaporins.
13 esembling the phenotype reported for altered aquaporin-0 activity without detectable cytotoxic effect
14 reated lenses was preceded by an increase in aquaporin-0 serine-235 phosphorylation and levels of con
15 a tetrameric alpha-helical membrane channel (Aquaporin-0) solubilized by n-Dodecyl beta-D-Maltoside a
16 ion of expression, activity and stability of aquaporin-0, connexins, cytoskeletal proteins, and the m
19 the osmotic-permeability regulation of human aquaporin 1 (hAQP1) expressed in Xenopus oocyte membrane
21 with the overexpression of the water channel aquaporin 1, which was prevented by reactive oxygen spec
24 ility, sensitivity, and specificity of urine aquaporin-1 (AQP1) and perilipin-2 (PLIN2) concentration
29 sed a prototype adenoviral vector to express aquaporin-1 (AQP1), presumably in the ductal cell layer
32 LIM-FRET) and identified interaction between aquaporin-1 and band 3 at a distance of 8 nm, within the
35 onic anhydrase enzymes and the water channel Aquaporin-1 for targeting this subpopulation of platelet
36 imilarity between the pf values of SGLT1 and aquaporin-1 makes a transcellular pathway plausible, it
39 tissue in diseased rats was vascularized by aquaporin-1(+) high endothelial venules and vascular cel
41 inase A (PKA) activation, phosphorylation of aquaporin 2 (AQP2) at serine 256, and translocation of A
44 ency led to a reduction in the percentage of aquaporin 2 (Aqp2)(+) principal cells (PCs) in the colle
45 KCC2), sodium chloride co-transporter (NCC), aquaporin 2 (AQP2), and EGFR abundances using western bl
46 odies against the exosomal proteins CD24 and aquaporin 2 (AQP2), conjugated to a fluorophore, we coul
49 tubular cells with ET but not PA, and urine aquaporin 2 levels were higher with ET (5.52 +/- 1.06 ng
52 ated potassium channel and the water channel aquaporin 2, and improved polyuria and hypokalemia in mu
53 s and prevented AVP-induced translocation of aquaporin 2, further suggesting the effects in SHR-A3 re
54 g the collecting duct-specific water channel aquaporin 2, whereas autoantibodies of the two other pat
55 C-like cells selectively integrated into the aquaporin 2-positive medullary collecting duct when micr
56 d mCCDcl1 cells, and DHHC 3 was expressed in aquaporin 2-positive principal cells of mouse aldosteron
61 interaction between the renal water channel aquaporin-2 (AQP2) and the lysosomal trafficking regulat
65 luminal fluid of the nephron occurs through aquaporin-2 (AQP2) water pores in principal cells that l
66 in abundance by vasopressin; interacts with aquaporin-2 (AQP2), Hsp70, and Hsc70; and can directly u
68 binds to the cytoplasmic PDZ-ligand motif of aquaporin-2 and accelerates its endocytosis in the absen
69 d dedifferentiation of CD cells with loss of aquaporin-2 and epithelial-mesenchymal transition-like p
70 ressin-regulated expression and insertion of aquaporin-2 channels in the luminal membrane of renal pr
72 the interaction, in association with reduced aquaporin-2 endocytosis and prolonged plasma membrane aq
75 utant kidneys showed increased expression of aquaporin-2 mRNA but mislocalized expression of aquapori
76 ith type I PDZ sequences from the C-tails of aquaporin-2 or GluR1 recycled in a SAP97- and PKA-depend
79 nary concentrating ability, with a preserved aquaporin-2 response to desmopressin and an intact respo
81 attenuated lithium-induced downregulation of aquaporin-2 through a mechanism different from that of a
85 echanisms that regulate the abundance of the aquaporin-2 water channel in renal collecting duct cells
86 nts that culminate in the phosphorylation of aquaporin-2 water channels and their redistribution from
87 A-dependent phosphorylation at serine 256 of aquaporin-2, which triggers the redistribution to the pl
88 xP-flanked PKD1 gene and heterozygous for an aquaporin-2-Cre recombinase transgene to achieve collect
95 ds on entry into the cell by transit through aquaporin-3 (AQP3), a plasma membrane H2O2-conducting ch
97 cooperation between the glial water channel aquaporin 4 (AQP4) and the transient receptor potential
99 neuritis (ON), the presence of antibodies to aquaporin 4 (AQP4) has diagnostic and prognostic value.
100 d protein) and supramolecular aggregation of aquaporin 4 (AQP4) in mouse, rat, and human tissues.
101 staining showed aberrant co-localization of aquaporin 4 (AQP4) in retracted GFAP+ astrocytes with di
104 ostasis.SIGNIFICANCE STATEMENT Water channel aquaporin 4 (AQP4) plays a key role in the regulation of
106 Moreover, mRNA expression of water channel, aquaporin 4 (AQP4) was increased after Dp71 deletion.
107 receptor potential isoform 4 (TRPV4) and the aquaporin 4 (AQP4) water channel in retinal Muller cells
108 tion of an astrocytic water channel protein, Aquaporin 4 (AQP4), is known to predominantly contribute
114 sability Status Scale score), change in anti-aquaporin 4 antibody, and safety of rituximab treatment.
116 s, an IgG autoantibody binding to astrocytic aquaporin 4, the principal water channel of the central
117 arget antigens included CASPR2, LGI1, NMDAR, aquaporin 4, Tr (DNER [delta/notch-like epidermal growth
121 ange, 13-81 years); 84% were women; 80% were aquaporin 4-IgG seropositive; and the median Expanded Di
123 e expression of the astrocytic water channel aquaporin-4 (AQP4) and changes in glymphatic pathway fun
124 onally, loss of astrocytic laminin decreases aquaporin-4 (AQP4) and tight junction protein expression
125 However, since the discovery of NMO-IgG or aquaporin-4 (AQP4) antibody (AQP4-antibody), an NMO-spec
126 ogy compatible with targeting of sarcolemmal aquaporin-4 (AQP4) by complement-activating IgG implies
134 toantibodies (NMO-immunoglobulin G [IgG]) to aquaporin-4 (AQP4) on astrocytes, which initiates comple
135 ular localization of the brain water channel aquaporin-4 (AQP4) was investigated during the neurologi
136 biogenesis, hydrophilic peptide loops of the aquaporin-4 (AQP4) water channel are delivered to cytoso
138 earance mechanism additionally suggests that aquaporin-4 (AQP4) water channels facilitate convective
139 s optica-immunoglobulin G (NMO-IgG) binds to aquaporin-4 (AQP4) water channels in the central nervous
140 ous studies have reported an upregulation of aquaporin-4 (AQP4), a water channel protein, following b
143 e-specific major water channel in the brain, aquaporin-4 (AQP4), in brain plasticity and learning.
144 -IgGs) against supra-molecular assemblies of aquaporin-4 (AQP4), known as orthogonal array of particl
147 e discovery of serum antibodies (Ab) against aquaporin-4 (AQP4), which unequivocally differentiate NM
148 ord MRIs for ring-enhancing lesions from 284 aquaporin-4 (AQP4)-IgG seropositive patients at Mayo Cli
149 ptic neuritis, multiple sclerosis (MS), anti-aquaporin-4 (AQP4)-negative neuromyelitis optica (NMO),
152 pectrum disorder have autoantibodies against aquaporin-4 (AQP4-Abs), but recently, myelin-oligodendro
153 known to modulate edema formation, including aquaporin-4 and AMP-activated protein kinase and its dow
154 Patients with neuromyelitis optica who have aquaporin-4 antibodies are being identified and receivin
155 rtunistic retinal infection in patients with aquaporin-4 antibodies who are receiving immunosuppressa
156 nistic infections can occur in patients with aquaporin-4 antibodies who are receiving relatively low
158 come, and prognostic features in relation to Aquaporin-4 antibody (AQP4-Ab) status, and compared to a
159 O according to Wingerchuk's 2006 criteria or aquaporin-4 antibody-positive NMO spectrum disorder (NMO
160 ing in the setting of neoplasia suggest that aquaporin-4 autoimmunity may in some cases have a parane
161 athogenic IgG that competes with NMO-IgG for aquaporin-4 binding, significantly reduced NMO-IgG and h
164 OSD whose test results were seropositive for aquaporin-4 IgG and who had a hepatic metastasis from a
168 t of cerebral edema; 2) perivascular pool of aquaporin-4 plays a critical role in water egress from b
169 yn) that demonstrate diminished perivascular aquaporin-4 pool but retain the non-endfoot and ependyma
172 content, blood-brain barrier disruption, and aquaporin-4 protein expression were determined at 24 hou
173 etiformis and antibody test findings against aquaporin-4 were positive, leading to a diagnosis of neu
176 eally injected NMO-IgG binds mouse placental aquaporin-4, activates coinjected human complement, and
177 synthetase, glutamate transporter 1 (GLT1), aquaporin-4, aldehyde dehydrogenase 1 family member L1,
178 hich recognize the immunodominant epitope of aquaporin-4, exhibit Th17 polarization and cross-react w
179 as no damage to maternal organs that express aquaporin-4, including the brain, spinal cord, kidneys,
181 e gene encoding the astroglial water channel aquaporin-4, which is importantly involved in paravascul
183 ence (on December 31, 2011) of NMO/NMOSD and aquaporin-4-IgG seroincidence and seroprevalence (sera c
184 idemiological studies are limited by lack of aquaporin-4-IgG seroprevalence assessment, absence of po
191 st, expression of TMEM16A, the water channel aquaporin 5 (AQP5), and other regulators of sweat gland
192 secretion accompanied by down-regulation of aquaporin 5 and an increase in anti-M3R autoantibodies.
193 mma markedly improved salivary secretion and aquaporin 5 expression in anti-PD-L1-treated NOD/ShiLtJ
195 carinic Acetylcholine receptor M3) and AQP5 (Aquaporin 5) protein expression, b) decreased saliva sec
199 7 induces expression of the glycerol channel aquaporin 9 (AQP9) in virus-specific memory CD8+ T cells
201 rt during salt stress conditions to modulate aquaporin activity, thereby significantly altering the p
207 aperone-like genes or the down-regulation of aquaporins and metal transmembrane transporters that was
208 Diffusivity was unaffected by blockers of aquaporins and Rh complex (Hg(2+), p-chloromercuribenzoi
211 report the results of a multicentre study of aquaporin (AQP) 4 antibody (AQP4-Ab) assays in neuromyel
212 GABA(A)Rs colocalize with the water channel aquaporin (AQP) 4 in prominin-1 immunopositive (P(+)) pr
216 tatic field emanating from the center of the aquaporin (AQP) water and solute channel is responsible
217 e regulation might include interactions with aquaporin (AQP) water channel isoforms, although the pro
224 Our understanding of the cellular role of aquaporins (AQPs) in the regulation of whole-plant hydra
228 ipts associated with stress avoidance (e.g., aquaporins), as well as those involved in the prevention
230 draulic conductivity can be accounted for by aquaporins but this must be integrated with anatomical c
232 This suggests that the hourglass shape of aquaporins could be the result of a natural selection pr
237 ROS-scavenging system, Heat Shock Proteins, aquaporins, expansins, and desiccation related proteins
238 r mixed populations comprising as few as 10% aquaporin-expressing cells are sufficient to produce MRI
241 revealed that tls1 encodes a protein in the aquaporin family co-orthologous to known B channel prote
243 unravel how FaPIP1;1, a fruit-specific PIP1 aquaporin from Fragaria x ananassa, contributes to the m
245 n of plasma membrane intrinsic protein (PIP) aquaporins from the plasma membrane (PM) to intracellula
246 the identification and characterization of a aquaporin gene, MusaPIP2;6 which is involved in salt str
248 7 and SlPIP2;5, were identified as candidate aquaporins genes because of highly expressed in tomato r
250 asma membrane Intrinsic Protein 2;1 (PIP2;1) aquaporin have a defect in stomatal closure, specificall
253 effect on intercellular water trafficking by aquaporins in stem xylem during soil drying and recovery
254 a polarized distribution of Na+/H+ pumps and aquaporins in the cell membrane, which creates a net inf
255 OsPIP1;3 and OsPIP2;6 lines was inhibited by aquaporin inhibitors, silver nitrate and sodium azide.
256 simultaneous transcriptional repression and aquaporin internalization to modify root cell water cond
257 lipid composition we are able to direct the aquaporin into specific immiscible liquid domains in gia
258 t the individual and integrated functions of aquaporins involved in drought response remains unclear.
260 expression of the main root plasma membrane aquaporins is associated with the increase of root hydra
261 indings establish how regulation of a single aquaporin isoform in leaf veins critically determines le
264 hether the characteristic hourglass shape of aquaporins may arise from a geometrical optimum for such
265 the narrowest opening in naturally occurring aquaporins measuring approximately 3 A across, and hence
268 ions between specific SNARE proteins and PIP aquaporins modulate their post-Golgi trafficking and thu
270 , boric acid, and H2O2 Thus, we propose that aquaporins NIP4;1 and NIP4;2 are exclusive components of
273 otrimeric G protein subunit interactions and aquaporin oligomerization, >99% of the interactions were
276 the particular case of plant plasma membrane aquaporins (PIPs), PIP1 and PIP2 monomers interact to fo
277 tal complexes and showed that members of the aquaporin plasma membrane intrinsic protein (PIP) subfam
282 ntact xylem, phloem, and parenchyma, whereby aquaporins reduce resistances along the symplastic pathw
285 n: the dual asparagine-proline-alanine (NPA) aquaporin signature motif and the aromatic and arginine
286 Taken together, this study concludes that aquaporins (SlPIP2;1, SlPIP2;7 and SlPIP2;5) contribute
288 s) plasma membrane intrinsic protein (ZmPIP) aquaporin subfamily, which is divided into two sequence-
289 lasma membrane intrinsic proteins (PIPs) are aquaporins that facilitate the passive movement of water
290 sion across cell membranes is facilitated by aquaporins that provide plants with the means to rapidly
291 ion to information on cellular regulation of aquaporins, this study provides novel and complementary
293 also altered, as shown by retargeting of the aquaporin TIP1g from the tonoplast membrane to the symbi
294 gulation of membrane transporters, including aquaporin water channels and sugar transporters, and myc
296 elated dynamics of molecules passing through Aquaporin water transport complexes located within the i
297 HpUreI conducts water at rates equivalent to aquaporins, which might be essential for efficient trans
298 ervous system (CNS) and on the regulation of aquaporins while LXRalpha has its most marked effects on
300 e (MscL) from Mycobacterium tuberculosis and aquaporin Z (AqpZ) and the ammonia channel (AmtB) from E
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