ライフサイエンスコーパス: aquaporin 1

1 of Na(+)/Pi cotransporter 2, claudin-2, and aquaporin 1.

2 or H7, and blocked by HgCl2, an inhibitor of aquaporin 1.

3 I reporters based on the human water channel aquaporin 1.

4 nown structures of the KcsA K(+) channel and aquaporin 1.

5 orter and the proximal tubule water channel, aquaporin-1.

6 of water-only transport pathways mediated by aquaporin-1.

7 igation of the water-permeation mechanism of aquaporin-1.

8 ormed on the structures of the water channel aquaporin-1.

9 e was no decrease in the renal expression of aquaporins 1, 3, or 4.

10 it affect the distribution or expression of aquaporins 1, 3, or 4.

11 helial cell adhesion molecule 1 (PECAM), and aquaporin 1, a marker of vasculogenesis.

12 Aquaporin 1, a six-transmembrane domain protein, is a wa

13 identified and characterized the A. gambiae aquaporin 1 (AgAQP1) protein that is homologous to AQPs

14 , P-cadherin and beta-catenin) and function (aquaporin 1 and carbonic anhydrase IX).

15 c resolution crystal structures of mammalian aquaporin 1 and the bacterial glycerol permease GlpF.

16 LIM-FRET) and identified interaction between aquaporin-1 and band 3 at a distance of 8 nm, within the

17 Adaptable interaction between aquaporin-1 and band 3 reveals a potential role of water

18 Aquaporin-1 and Na/H exchanger-3 deficiency enhances TGF

19 GFR difference was found to be augmented in aquaporin-1 and Na/H exchanger-3 knockout mice, suggesti

20 In contrast, the expression levels of aquaporin-1 and the all subunit of the Na-K-ATPase were

21 Aquaporin-1 and versican were downregulated in the HCM,

22 orins 3 and 8 in primitive erythroblasts and aquaporins 1 and 9 in adult definitive erythroblasts.

23 hich in large part occurs via a gas channel (aquaporin 1) and acidifies the cell.

24 alpha-helical transmembrane domains (opsin, aquaporin 1, and a connexin) with their area obtained fr

25 e to those through the transmembrane protein aquaporin-1, and are practically independent of the leng

26 Aquaporin-1 (AQP-1), the universal water channel, is res

27 The water channel aquaporin 1 (AQP1) and certain Rh-family members are per

28 ed after the known mercury-sensitive site of aquaporin 1 (AQP1) and determined the X-ray crystal stru

29 ity map of deglycosylated, human erythrocyte aquaporin 1 (AQP1) determined at 4 A resolution in plane

30 However, abundantly expressed aquaporin 1 (AQP1) in erythrocytes is thought not to be

31 analysis and identified clear expression of aquaporin 1 (AQP1) in seven cell lines.

32 Aquaporin 1 (AQP1) is a plasma membrane water-transporti

33 rmine the roles of lipid composition and the aquaporin 1 (AQP1) water channel in altering CO2 flux ac

34 this remained unknown until discovery of the aquaporin 1 (AQP1) water channel protein.

35 Here we report the structure of the aquaporin 1 (AQP1) water channel to 2.2 A resolution.

36 Further, our results identify aquaporin 1 (AQP1), a potent effector of fluid volume re

37 Na(+)/glucose cotransporter 1 (SGLT1) and of aquaporin 1 (Aqp1), a water channel, at the attachment s

38 cell SGLT1, a Na+/glucose cotransporter, and aquaporin 1 (AQP1), a water channel, to the attachment s

39 gulated by secretin-responsive relocation of aquaporin 1 (AQP1), a water-selective channel protein, f

40 Dex-treated rats had increased abundance of aquaporin 1 (AQP1), AQP3, and Na-K-2Cl co-transporter pr

41 n studies that OEG express the water channel aquaporin 1 (AQP1), both in vivo and in vitro.

42 Additionally, the water channel protein aquaporin 1 (AQP1), expressed at high levels in erythroc

43 ons of CBCECs with an antibody against human aquaporin 1 (AQP1).

44 uggested that this is not the case for human aquaporin 1 (AQP1).

45 Expression of aquaporin-1 (AQP1) and -2 (AQP2) channels in the kidney

46 e retinal pigment epithelium (RPE) expresses aquaporin-1 (AQP1) and components of the natriuretic pep

47 ility, sensitivity, and specificity of urine aquaporin-1 (AQP1) and perilipin-2 (PLIN2) concentration

48 Aquaporin-1 (AQP1) enables greatly enhanced water flux a

49 Aquaporin-1 (AQP1) expression is induced by hypertonicit

50 Aquaporin-1 (AQP1) facilitates the osmotic transport of

51 er channel activity, several studies suggest Aquaporin-1 (AQP1) functions as a nonselective monovalen

52 cytes and liposomes containing water channel aquaporin-1 (AQP1) have suggested that AQP1 is able to t

53 The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia and aquap

54 The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia, AQP4 in

55 Aquaporin-1 (AQP1) is a major intrinsic protein that fac

56 Aquaporin-1 (AQP1) is a member of a family of integral m

57 Aquaporin-1 (AQP1) is a member of the membrane intrinsic

58 Aquaporin-1 (AQP1) is a water channel expressed strongly

59 Aquaporin-1 (AQP1) is a water channel protein expressed

60 Aquaporin-1 (AQP1) is a water channel that is induced by

61 Aquaporin-1 (AQP1) is a water channel, overexpressed in

62 Aquaporin-1 (AQP1) is an integral membrane protein that

63 Prevention of cation permeation in wild-type aquaporin-1 (AQP1) is believed to be associated with the

64 Water channel aquaporin-1 (AQP1) is expressed at epithelial cell plasm

65 Water channel aquaporin-1 (AQP1) is expressed in erythrocytes and vari

66 nce is presented here that the water channel aquaporin-1 (AQP1) is present in the ZG membrane and par

67 Water channel aquaporin-1 (AQP1) is strongly expressed in kidney in pr

68 Aquaporin-1 (AQP1) is the principal water-transporting p

69 Aquaporin-1 (AQP1) is the prototype integral membrane pr

70 igid body docking of the atomic model of the aquaporin-1 (AQP1) tetramer showed that the freeze-fract

71 The aquaporin-1 (AQP1) water channel is a potentially import

72 For example, in Xenopus oocytes, the aquaporin-1 (AQP1) water channel is cotranslationally di

73 Aquaporin-1 (AQP1) water channel protein expression is i

74 Aquaporin-1 (AQP1) water channels are expressed in the p

75 Aquaporin-1 (AQP1) water channels are expressed widely i

76 To investigate the role of aquaporin-1 (AQP1) water channels in proximal tubule fun

77 known blockers of water permeability through aquaporin-1 (AQP1) water channels were mercurial reagent

78 ich were proposed to consist of tetramers of aquaporin-1 (AQP1) water channels.

79 The aquaporin-1 (AQP1) water transport protein contains a po

80 ected with cRNA encoding either human or rat aquaporin-1 (AQP1) were used as controls.

81 sed a prototype adenoviral vector to express aquaporin-1 (AQP1), presumably in the ductal cell layer

82 The UT-B inhibitors did not reduce aquaporin-1 (AQP1)-facilitated water transport.

83 transport water mainly via the water channel aquaporin-1 (AQP1).

84 proximal tubule is mediated predominantly by aquaporin-1 (AQP1).

85 tion has been observed for several including aquaporin-1 (AQP1).

86 T-B and the major erythrocyte water channel, aquaporin-1 (AQP1).

87 gy (Ea = 3.7 kcal/mol), similar to mammalian aquaporin-1 (AQP1).

88 ncluding cytokeratin 19, integrin beta4, and aquaporin-1, but not a hepatocyte marker, albumin.

89 sporting capacity, which lags behind that of aquaporin-1 by 3 orders of magnitude.

90 efficacy of serotype 5, adenoviral-mediated aquaporin-1 cDNA transfer to a single previously irradia

91 The cationic permeability of the aquaporin 1 channel is activated by a cyclic adenosine m

92 mulations using this method are performed on aquaporin-1 channels in a lipid bilayer, resulting in a

93 In Xenopus oocytes injected with aquaporin 1 complementary RNA, the application of forsko

94 d with altered tumor vasculature produced by aquaporin-1 deletion.

95 Expression of aquaporin-1 did not alter P(CO2) (and thus the limiting

96 Molecular dynamics simulations of aquaporin-1 embedded in a solvated lipid bilayer were ca

97 administration was traced to a reduction in aquaporin-1 expression in the kidney of LXRbeta(-/-) mic

98 mal polarization of alkaline phosphatase and aquaporin-1 for 7 mo, without teratoma formation.

99 onic anhydrase enzymes and the water channel Aquaporin-1 for targeting this subpopulation of platelet

100 activity until Agre and colleagues purified aquaporin-1 from human erythrocytes and reported its cDN

101 the osmotic-permeability regulation of human aquaporin 1 (hAQP1) expressed in Xenopus oocyte membrane

102 The adenoviral gene transfer of human aquaporin-1 (hAQP1) water channels to the liver of 17alp

103 cient, recombinant adenovirus encoding human aquaporin-1 (hAQP1), the archetypal water channel, was c

104 tissue in diseased rats was vascularized by aquaporin-1(+) high endothelial venules and vascular cel

105 They proved that aquaporin-1 is a specific water channel by cRNA expressi

106 data indicate that the carboxyl terminus of aquaporin-1 is intracellular and that loops C and E are

107 imilarity between the pf values of SGLT1 and aquaporin-1 makes a transcellular pathway plausible, it

108 ermined pd value, we conclude that pf/pd for aquaporin-1 measures approximately 12.

109 Aquaporin-1 mediates proximal tubule fluid reabsorption,

110 The water-selective pathway through the aquaporin-1 membrane channel has been visualized by fitt

111 MUTM-NEI/1 cells expressed mRNA for NCAM, aquaporin 1, myocilin/trabecular meshwork glucocorticoid

112 could dictate a lower level of expression of aquaporin-1 on the mature red cell surface.

113 id-reconstituted two-dimensional crystals of aquaporin-1 preserved in vitrified buffer in the absence

114 Aquaporin-1 protein abundance was not significantly decr

115 in the exosomal sorting of the water channel aquaporin-1 represents a newly described mechanism by wh

116 on, RGS4 expression inhibited trafficking of aquaporin 1 to the plasma membrane in LLC-PK1 cells and

117 together with recent studies that show that aquaporin 1 transports both CO2 and O2.

118 Finally, a high level of aquaporin 1 unexpectedly appeared at the apical surfaces

119 In particular, aquaporin-1 upregulation occurred in acquired resistance

120 serted at sequential sites within TM2 of the aquaporin-1 water channel by in vitro translation of tru

121 induces the exocytic insertion of functional aquaporin-1 water channels (AQP1) into the apical membra

122 synthase, but the expression of endothelial aquaporin-1 water channels was unaltered.

123 t analysis showed approximately 1.4 x 10(12) aquaporin-1 water channels/cm2 of capillary surface, whi

124 with the overexpression of the water channel aquaporin 1, which was prevented by reactive oxygen spec