ライフサイエンスコーパス: arbovirus

1 a medically important arthropod-borne virus (arbovirus).

2 ned, especially for arthropod-borne viruses (arboviruses).

3 sures acting on arthropod-borne RNA viruses (arboviruses).

4 st Nile virus, a globally-spreading zoonotic arbovirus.

5 and effect on mosquito vector competence for arboviruses.

6 ury associated with infection by neurotropic arboviruses.

7 y resembling that of other insect vectors of arboviruses.

8 ishmania, Bartonella bacilliformis, and some arboviruses.

9 n determining mosquito vector competence for arboviruses.

10 generate viral siRNAs when infected with RNA arboviruses.

11 alphaviruses and flaviviruses but not other arboviruses.

12 ose of potentially oncogenic, mosquito-borne arboviruses.

13 tor infection may constrain the evolution of arboviruses.

14 ssion for the biocontrol of Ae. aegypti-born arboviruses.

15 e-off hypothesis may not be accurate for all arboviruses.

16 significant constraints on genetic change of arboviruses.

17 ntiviral defense in mosquitoes infected with arboviruses.

18 fer protection for Ae. aegypti against other arboviruses.

19 g globally without cross-reacting with other arboviruses.

20 ber of mosquito species are able to transmit arboviruses.

21 have important evolutionary implications for arboviruses.

22 y be useful to anticipate epidemic spread of arboviruses.

23 or antiviral mechanism in arthropods against arboviruses.

24 ion for the T/BG such as M. tuberculosis and arboviruses, a surprisingly high number of cases were as

25 des albopictus, a vector of dengue and other arboviruses, abolished the transmission capacity of deng

26 These results suggest that arbovirus adaptation and evolution is limited by obligat

27 expansion and vectorial capacity for various arboviruses affect an increasingly larger proportion of

28 Sindbis virus, an arbovirus and prototypic alphavirus having an inner prot

29 nuisance and an efficient vector of certain arboviruses and filarial nematodes.

30 ons for susceptibility to three encephalitic arboviruses and found that replication of Old World and

31 mosquitoes could prevent the transmission of arboviruses and other human parasites.

32 Arboviruses and plant tumour promoters are other possibl

33 anticipated changes in global climate on the arboviruses and the diseases they cause poses a signific

34 BG group included Creutzfeldt-Jakob disease, arbovirus, and Mycobacterium tuberculosis.

35 ic and wild animals, but it is as vectors of arboviruses, and particularly arboviruses of domestic li

36 Mosquito-borne arboviruses are a major source of human disease.

37 Consequently, although arboviruses are able to successfully adapt to diverse ce

38 Most alphaviruses and many other arboviruses are mosquito-borne and exhibit a broad host

39 evolution observed in natural populations of arboviruses are not necessarily due to the need for the

40 Arboviruses are transmitted by distantly related arthrop

41 Arboviruses are transmitted by mosquitoes and other arth

42 Arboviruses are transmitted to vertebrate hosts by bitin

43 The evolutionary origins of arboviruses are unknown because their typical dual host

44 Zika virus is an arbovirus (arthropod-borne virus) and a member of the fa

45 Nevertheless, arboviruses (arthropod-borne viruses) are capable of inf

46 Arboviruses (arthropod-borne viruses) represent quintess

47 Millions of people are infected each year by arboviruses (arthropod-borne viruses) such as chikunguny

48 This defines such an arbovirus as something whose transmission should be prev

49 Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flav

50 g dominant lethal genes, the introduction of arbovirus-blocking microbes into mosquito populations, a

51 n cycles constrain the evolutionary rates of arboviruses but not their fitness for either host alone.

52 His interests (always primarily arboviruses but now also rodent-borne viruses and bat-bo

53 Transmission of arboviruses by the bite of infected mosquitoes can poten

54 Thus, an arbovirus can evade the host antiviral response by induc

55 -sense RNA viruses, are globally distributed arboviruses capable of causing rash, arthritis, encephal

56 Recently, the spread of other arboviruses carried by invasive Aedes spp., such as Chik

57 Arboviruses cause acute diseases that increasingly affec

58 Zika virus (ZIKV), a previously little known arbovirus, caused an unprecedented outbreak in Latin Ame

59 Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal inflammato

60 by Venezuelan equine encephalitis virus, an arbovirus causing neurological disease in humans and equ

61 PORTANCE Dengue virus is the most widespread arbovirus, causing an estimated 390 million dengue infec

62 A promising candidate for arbovirus control and prevention relies on the introduct

63 ng Wolbachia strains are promising tools for arbovirus control, particularly as they have the potenti

64 Arthropod-borne viruses (arboviruses) cycle between hosts in two widely separated

65 sease vectors because it transmits two major arboviruses, dengue and yellow fever, which cause signif

66 llness, including infections with two common arboviruses, dengue virus and chikungunya virus.

67 The period of highest arbovirus discovery coincided with a comprehensive progr

68 Dengue is the most prevalent human arbovirus disease in the world.

69 One strategy to reduce arbovirus disease is to reduce the mosquito's ability to

70 Mosquitoes transmit Plasmodium and certain arboviruses during blood feeding, when they are injected

71 that mosquitoes could be exposed to multiple arboviruses during one feeding episode.

72 To investigate whether arboviruses encounter bottlenecks during dissemination i

73 ese findings have important implications for arbovirus evolution and will help elucidate the viral fa

74 These results support the hypothesis that arbovirus evolution may be constrained by alternating ho

75 rade-off hypothesis, the current paradigm of arbovirus evolution, proposes that cycling between verte

76 separately or in concert shape the course of arbovirus evolution.

77 and is caused by bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct ser

78 esting for different applications new to the arbovirus field.

79 of 25 vector-pathogen interactions involving arboviruses, filarial worms, bacteria, and malaria paras

80 stern equine encephalitis virus (WEEV) is an arbovirus from the genus Alphavirus, family Togaviridae,

81 determinants that facilitate transmission of arboviruses from a vector to a host.

82 Accordingly, freeing arboviruses from alternate replication via specializatio

83 a comprehensive array of medically important arboviruses from the Alphavirus, Flavivirus, and Bunyavi

84 gunya virus (ChikV), a reemerging pathogenic arbovirus, has been made by attenuating wild-type (WT) v

85 Chikungunya virus (CHIKV) and related arboviruses have been responsible for large epidemic out

86 us infection in mosquitoes and suggests that arboviruses have evolved mechanisms to avoid stimulating

87 Arboviruses have made unexpected reappearances in recent

88 nges in the epidemiology of Culicoides-borne arboviruses have occurred since 1998, including the emer

89 Arthropod-borne viruses (arboviruses) have a long history of emerging to infect h

90 ugh this information is important to compare arbovirus/host interactions in different classes of arbo

91 ivirus: Flaviviridae) is the most widespread arbovirus in the world.

92 insight into ZIKV can be found by evaluating arboviruses in domestic animals, of which there are at l

93 y is both induced by and restricts disparate arboviruses in Drosophila intestines, providing insight

94 induced on viral infection to restrict human arboviruses in insects.

95 relation between apoptosis and resistance to arboviruses in mosquitoes, there is no direct evidence t

96 major role in the antiviral response against arboviruses in mosquitoes.

97 unprecedented outbreaks of Culicoides-borne arboviruses in southern Europe has been a significant po

98 (ZIKV) is an emerging arthropod-borne virus (arbovirus) in the genus Flavivirus that has caused a wid

99 The Aedes aegypti mosquito transmits arboviruses, including dengue, chikungunya, and Zika vir

100 pe flies are refractory to oral infection by arboviruses, including Sindbis virus and vesicular stoma

101 sponse and whether this is effective against arboviruses, including those with double-stranded RNA (d

102 However, apoptosis is rarely seen in arbovirus-infected mosquito cells, raising questions abo

103 d the effect of stimulating apoptosis during arbovirus infection by infecting Aedes aegypti mosquitoe

104 Dengue is the most common arbovirus infection globally, but its burden is poorly q

105 itt's lymphoma, and symptoms compatible with arbovirus infection have been seen immediately before th

106 that apoptosis is a powerful defense against arbovirus infection in mosquitoes and suggests that arbo

107 et of genes that is rapidly transcribed upon arbovirus infection, including components of antiviral p

108 GN are expressed in several early targets of arbovirus infection, including dendritic cells (DCs) and

109 accine (TDV) against the world's most common arbovirus infection.

110 missive to and allow systemic and persistent arbovirus infection.

111 A unique facet of arthropod-borne virus (arbovirus) infection is that the pathogens are orally ac

112 tides, similar to the viRNAs produced during arbovirus infections of mosquitoes.

113 ission, and its interrelationship with other arbovirus infections.

114 could facilitate strategies for controlling arbovirus infections.

115 ile virus (WNV), the world's most widespread arbovirus, invaded the United States in 1999 and rapidly

116 in developed countries, and various endemic arboviruses is essential.

117 nvestigation of HS binding by this and other arboviruses is warranted.

118 ution in the laboratory, but like many other arboviruses, it evolves at a relatively slow rate in the

119 It is caused by an arbovirus known as bluetongue virus (BTV).

120 Culicoides midges are important vectors of arboviruses, known to transmit pathogens of humans and l

121 t have been submitted for WNV testing to the Arbovirus Laboratories of the Wadsworth Center.

122 The arbovirus life cycle involves viral transfer between a v

123 Arboviruses like dengue virus, yellow fever virus, and W

124 Arthropod-borne viruses (arboviruses) mainly infect people via direct spillover f

125 Alphaviruses represent a diverse set of arboviruses, many of which are important pathogens.

126 In theory, cross species transfers by arboviruses may be constrained by their alternating infe

127 ses, and in many cases mosquito-cell-derived arboviruses more efficiently infect DCs than viruses der

128 laria but are believed to transmit one known arbovirus, o'nyong-nyong virus, whereas Aedes mosquitoes

129 ican horse sickness virus (AHSV) is a lethal arbovirus of equids that is transmitted between hosts pr

130 gue virus (BTV) is an economically important arbovirus of ruminants that is transmitted by Culicoides

131 Schmallenberg virus (SBV) is an emerging arbovirus of ruminants that spread in Europe between 201

132 achment receptors for Sindbis (SB) virus, an arbovirus of the Alphavirus genus.

133 is an emerging mosquito-borne (Aedes genus) arbovirus of the Flaviviridae family.

134 outbreaks of bluetongue virus in Europe, an arbovirus of wild and domestic ruminants also transmitte

135 as vectors of arboviruses, and particularly arboviruses of domestic livestock, that they achieve the

136 Aedes aegypti mosquitoes vector several arboviruses of global health significance, including den

137 are abundant hematophagous flies that vector arboviruses of veterinary and medical importance.

138 Quaranfil virus (QRFV) is an unclassified arbovirus originally isolated from children with mild fe

139 No arboviruses other than dengue were identified.

140 molecules for arthropod-borne viruses, (ii) arbovirus particles produced in and delivered by arthrop

141 n vivo virus-host model system for exploring arbovirus pathogenesis and provides the first evidence f

142 While barriers limiting arbovirus population diversity have been observed in mos

143 w for the first time that midge cells target arbovirus replication by mounting an antiviral RNAi resp

144 Our study reveals that blood meals enhance arbovirus replication in mosquitoes through activation o

145 To determine whether apoptosis can influence arbovirus replication in mosquitoes, we manipulated apop

146 cific inhibitors both significantly impaired arbovirus replication.

147 As a result, low priority was given to arbovirus research investment and related public health

148 Chikungunya virus (CHIKV) is a reemerging arbovirus responsible for outbreaks of infection through

149 Arbovirus RNA detection by RT-PCR should be part of the

150 ification of coinfections, although targeted arbovirus screening may be sufficient in the current ZIK

151 Arboviruses seem to be associated with case clusters of

152 enomes (referred to as 'replicons') from the arbovirus Sindbis [2].

153 We report that the Arbovirus Sindbis can be used to deliver high levels of

154 immunity could provide new tools to control arbovirus spread.

155 The continuing emergence of arboviruses such as chikungunya virus requires thoughtfu

156 In particular, it is unclear why arboviruses such as dengue virus show substantial geneti

157 It is widely held that arboviruses such as the alphavirus Sindbis virus gain en

158 Arboviruses such as yellow fever virus (YFV) are transmi

159 the Americas of VEEV and other encephalitic arboviruses, such as eastern equine encephalitis virus a

160 However, in some mosquitoes, arboviruses survive antiviral RNA interference (RNAi) an

161 ce ecological understanding of these complex arbovirus systems.

162 Rift Valley fever virus (RVFV) is an arbovirus that is classified as a select agent, an emerg

163 provides a unique opportunity to observe an arbovirus that is in decline and to better understand wh

164 Zika virus (ZIKV) is yet another arbovirus that is rapidly emerging on a global scale, on

165 virus (CHIKV) is a mosquito-borne arthralgia arbovirus that is reemergent in sub-Saharan Africa and S

166 Chikungunya virus is an emerging arbovirus that is widespread in tropical regions and is

167 yaviridae) is composed of a diverse group of arboviruses that cause disease syndromes ranging from mi

168 infecting both mammals and insects just like arboviruses that use insect vectors to infect plants.

169 Alphaviruses are arthropod-borne viruses (arboviruses) that include a number of important human an

170 Alphaviruses are arthropod-borne viruses (arboviruses) that include a number of important human an

171 For other pathogens such as the arboviruses, the focus has been on prevention by vector

172 or, the susceptibility of disease vectors to arboviruses, the immunological control of infection in d

173 Arthropod-borne viruses (arboviruses) threaten the health of humans, livestock, a

174 viously uncharacterized mechanism used by an arbovirus to manipulate host immunity.

175 aracterized by the efficiency of an ingested arbovirus to replicate and become infectious in the mosq

176 This ability of arboviruses to infect arthropods and vertebrates is usua

177 is virus (LCMV), or the sand fly-transmitted arbovirus Toscana virus (TOSV).

178 lls in investigations of the cell biology of arbovirus transmission and entry into mammalian hosts.

179 Understanding the role of the vector in arbovirus transmission has provided critical practical a

180 BTV is an arbovirus transmitted between its ruminant hosts by Culi

181 minants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides.

182 AYV), causative agent of Mayaro Fever, is an arbovirus transmitted by Haemagogus mosquitoes.

183 Chikungunya, a re-emerging arbovirus transmitted to humans by Aedes aegypti and Ae.

184 Bluetongue virus (BTV) is an arbovirus transmitted to livestock by midges of the Culi

185 Other arboviruses transmitted by Ae. aegypti include the 2 fla

186 ke viruses that undergo direct transmission, arboviruses utilize an arthropod vector (e.g., mosquitos

187 Implications for arbovirus vector competence in mosquitoes are discussed.

188 ere is no direct evidence tying apoptosis to arbovirus vector competence.

189 Aedes albopictus, another highly invasive arbovirus vector that has only been implicated in one co

190 nt-induced speciation, as well as control of arbovirus vectors and agricultural pests, the bacterial

191 onger (22 nucleotides) than those from other arbovirus vectors and mapped at highest frequency to the

192 e small regulatory RNA pathways of the major arbovirus vectors, Ae. aegypti and Cx. pipiens, are evol

193 iviral RNAi between the two major classes of arbovirus vectors, and our data broadens our understandi

194 us/host interactions in different classes of arbovirus vectos.

195 n addition, there is only one other NT human arbovirus (Venezuelan equine encephalitis virus), which

196 ially important for arthropod-borne viruses (arboviruses) which belong to at least three virus famili

197 mount of genetic diversity compared to other arboviruses, which has been linked to increased virulenc

198 Chikungunya virus (CHIKV) is an arbovirus with a high potential to spread globally.

199 Recoded arboviruses with a bias toward phylum-specific expressio

200 Rift Valley fever virus (RVFV) is an arbovirus within the Bunyaviridae family capable of caus

201 renewed interest in monitoring and modeling arboviruses within mosquito vectors.