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1  protein complexes and interactions has been arduous.
2 cting high quality research is also becoming arduous.
3 oaches to investigating mycolylation rely on arduous analytical methods that occur outside the contex
4        The current drug discovery process is arduous and costly, and a majority of the drug candidate
5                      However, the process is arduous and for high-throughput applications needs to be
6 , these antibody-discovery methods are often arduous and identify only a few candidates from numerous
7                                    Given how arduous and lengthy this process can be, we sought to de
8                              This process is arduous and requires large amounts of RNA.
9 e-determining factor in new research, may be arduous and slow.
10 ny benchtop characterization methods require arduous and time-consuming procedures, and multiple assa
11                     Current HCV treatment is arduous and uptake is low, but new highly effective and
12 ver, the process of isolating these cells is arduous, and the rarity of CSCs makes it difficult to te
13     Important real-world decisions are often arduous as they frequently involve sequences of choices,
14                        Practically, the most arduous barrier to be overcome was the separation of the
15 egant, the path to clinical reality has been arduous because of the challenge on delivery technologie
16 estigators' lenses for decades, prompting an arduous but persistent race to uncover the mystery of th
17 e need for matrix-matched standards or other arduous calibration protocols and procedures to mitigate
18 ratory for the first time in 2004 through an arduous campaign involving novel strategies and tactics,
19 tional reactivation of p53 pathway, although arduous, can potentially provide a broad-based strategy
20 ntrolling target gene expression is still an arduous challenge.
21 rops, transformation and regeneration remain arduous even after more than 30 years of technological a
22 rowsing of chromatin contacts, thus reducing arduous Hi-C analysis into an easy yet flexible pipeline
23                                Many years of arduous investigation and the development of novel prote
24  the marginalized patient population and the arduous nature of current treatments.
25 lls, where alternative approaches are either arduous or frequently ineffective.
26  a conventional banded karyotype followed by arduous positional cloning projects.
27 ave long passed and have been replaced by an arduous process in which a drug is designed to target a
28 ntifying bacteria in natural specimens is an arduous process.
29 ical staff should be prepared for a lengthy, arduous rehabilitation process.
30 ors have been made possible by extensive and arduous research.
31 ensitivity, specificity, or requirements for arduous sample preparation or signal amplification proce
32 evant discoveries have relied heavily on the arduous, somewhat subjective process of manual microscop
33 ry structure of such protein complexes is an arduous task and usually requires the combination of mul
34  elucidation of their structures has been an arduous task as the metabolites are obtained in vanishin
35             This will avoid the increasingly arduous task of extensive screening of bacteria and othe
36 ng switching and memory while mitigating the arduous task of nanoscale patterning.
37 ecific histone PTMs to gene expression is an arduous task requiring large amounts of highly purified
38 biological data from these experiments is an arduous task that demands close attention to many detail
39 biological data from these experiments is an arduous task that demands close attention to many detail
40 olecular I-motifs has been a challenging and arduous task using conventional NMR spectral assignment
41  oxidized perovskite films is found to be an arduous task, filling some of oxygen vacancies into SrCo
42 ization can be time-consuming and overall an arduous task.
43 ative sleep while cared for in the ICU is an arduous task.
44 istribution and aggregate architecture is an arduous task.
45 to the larger collection of mutations remain arduous tasks.
46 n of available states, makes it increasingly arduous to reach equilibrium in that regime.
47 ifficult to isolate from natural sources and arduous to synthesize.
48 which does not require specialist, and often arduous, training to use.
49 dt's initial discovery, there was a long and arduous transformation of ideas and paradigms that event
50 of 0.954 and is therefore comparable to more arduous typing systems, such as pulsed-field gel electro
51                                         This arduous work has yielded results with far-reaching conse

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