ライフサイエンスコーパス: areata

1 T cell-mediated hair loss disease (alopezia areata).

2 didate genes in the pathogenesis of alopecia areata.

3 similar to those observed in human alopecia areata.

4 erstanding of the genetic basis for alopecia areata.

5 juvenile idiopathic arthritis, and alopecia areata.

6 agent for limited patchy childhood alopecia areata.

7 igh-incidence model for spontaneous alopecia areata.

8 s a key step in the pathogenesis of alopecia areata.

9 buting factor in the development of alopecia areata.

10 fluvium, androgenetic alopecia, and alopecia areata.

11 ing the use of these treatments for alopecia areata.

12 s potentially associated with human alopecia areata.

13 C57BL/6J mice do not develop alopecia areata.

14 ng this locus as being important in alopecia areata.

15 he IL-1RN and various phenotypes of alopecia areata.

16 n grafts from mice with spontaneous alopecia areata.

17 ic inflammatory diseases, including alopecia areata.

18 for decubitus ulcer, and 0.01% for alopecia areata.

19 whereas 39 of 44 controls developed alopecia areata.

20 ic alopecia (37.3 128.4, 46.1]) and alopecia areata (24.9 [17.2, 32.6]) were statistically significan

21 We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatit

22 Treatments for alopecia areata (AA) have evolved over the decades from broad and

23 However, vitiligo and alopecia areata (AA) have not been well characterized in the chro

24 g been appreciated that episodes of alopecia areata (AA) have occurred after severely stressful life

25 universalis is an uncommon form of alopecia areata (AA) involving hair loss over the entire scalp an

26 Alopecia areata (AA) is a common autoimmune disease resulting fro

27 Alopecia areata (AA) is a common T cell-mediated disorder with li

28 Alopecia areata (AA) is a genetically determined, immune-mediated

29 Alopecia areata (AA) is a non-scarring inflammatory hair loss dis

30 Alopecia areata (AA) is among the most highly prevalent human aut

31 Alopecia areata (AA) is an autoimmune disease of the hair follicl

32 Alopecia areata (AA) is an autoimmune disease that attacks anagen

33 Alopecia areata (AA) is an autoimmune disease that targets active

34 Alopecia areata (AA) is an autoimmune disorder of the hair follic

35 Alopecia areata (AA) is characterized by hair loss in patches and

36 Characterizing blood profile of alopecia areata (AA) is important not only for treatment advancem

37 Alopecia areata (AA) is one of the most common forms of human hai

38 Alopecia areata (AA), a non-scarring inflammatory hair loss disor

39 Alopecia areata (AA)-like hair loss in C3H/HeJ mice provides an e

40 eased in patients with vitiligo and alopecia areata (AA).

41 was reported to play a key role in alopecia areata (AA).

42 Alopecia areata affected and resistant mice were characterized to

43 Grafting alopecia areata affected C3H/HeJ mouse skin to littermates induce

44 In alopecia areata affected humans, 95 genes were significantly modu

45 lus, but only lymph node cells from alopecia areata affected mice displayed an increased response wit

46 s, lymph node and spleen cells from alopecia areata affected mice injected into normal haired litterm

47 4+ CD8+ expressing cells in chronic alopecia areata affected mice using monoclonal antibodies permitt

48 Alopecia areata affected skin contained increased numbers of CD4+

49 ll-mediated autoimmune disease, but alopecia areata affected skin graft hosts may resist alopecia are

50 Of 44 mice that received alopecia areata affected skin grafts but failed to develop alopec

51 a, only two of 22 receiving further alopecia areata affected skin grafts developed alopecia areata, w

52 s clinic, 2 to 16 years of age with alopecia areata affecting at least 10% of scalp surface area, wer

53 Alopecia areata affects 1%-2% of the population and is hypothesiz

54 For comparison, skin biopsies from alopecia areata and androgenetic alopecia affected humans were al

55 peutic techniques for patients with alopecia areata and further refine which subtypes of the disease

56 disease, thyroid disease, vitiligo, alopecia areata and inflammatory bowel disease) were self-reporte

57 ated with Crohn disease, psoriasis, alopecia areata, and leprosy.

58 gen, such as androgenetic alopecia, alopecia areata, and telogen effluvium.

59 itiligo," "seborrheic dermatitis," "alopecia areata," and "lichen planus." Diverse study populations

60 es of 110 patients and 45 controls: alopecia areata, ankylosing spondylitis, dermatomyositis, Graves'

61 essing this TCR develop spontaneous alopecia areata at nearly 100% incidence.

62 observed between IL-1RN and patchy alopecia areata but it was not statistically significant (p =0.06

63 J mouse skin to littermates induces alopecia areata, but high dietary soy oil reduces alopecia areata

64 In a rodent model, alopecia areata can be induced in normal haired C3H/HeJ mice by t

65 downregulated during onset of mouse alopecia areata consistent with an inflammatory cell-mediated dis

66 psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fungal skin

67 rds the graft, it is suggested that alopecia areata develops as a consequence of an inappropriate imm

68 and functional status in extensive alopecia areata (EAA) scalp skin.

69 One patient with extensive alopecia areata experienced skin atrophy that resolved spontaneou

70 C3H/HeJ mice spontaneously develop alopecia areata from 5 mo of age and older in females and later i

71 Few treatments for alopecia areata have been well evaluated in randomized trials.

72 rize a new high-incidence model for alopecia areata in C57BL/6J mice, the first to our knowledge to a

73 that is known to be associated with alopecia areata in humans.

74 (+) T effector memory cells mediate alopecia areata in part through Janus kinase (JAK) signaling and

75 These results suggest alopecia areata is a cell-mediated autoimmune disease, but alopec

76 Alopecia areata is a suspected autoimmune hair loss disease.

77 Alopecia areata is accompanied by Th2/Tc2 activation in skin-homi

78 Alopecia areata is among the most prevalent autoimmune diseases,

79 Alopecia areata is an autoimmune disease that targets actively gr

80 Alopecia areata is an idiopathic cause of hair loss with limited

81 Alopecia areata is an immune-mediated, nonscarring form of hair l

82 Alopecia areata is an inflammatory hair loss disease with a major

83 cy of currently used treatments for alopecia areata is lacking.

84 Alopecia areata is less common, but may be distressing, especiall

85 Alopecia areata is one of the most frequent organ-restricted auto

86 ve been implicated, the genetics of alopecia areata is still unclear.

87 stion regarding the pathogenesis of alopecia areata is the potential linkage with the brain.

88 nus kinase (JAK) signaling and that alopecia areata might be treated with JAK inhibitors.

89 0), androgenetic alopecia (n = 52), alopecia areata (n = 17), and alopecia areata totalis/universalis

90 Alopecia areata (n=138) and clinically normal (n=214) mice were g

91 ering all patients with any form of alopecia areata, no association was found with IL-1RN.

92 In addition, although alopecia areata often results in significant psychological distre

93 d skin grafts but failed to develop alopecia areata, only two of 22 receiving further alopecia areata

94 Alopecia areata onset could be inhibited in skin-grafted mice by

95 ffected skin graft hosts may resist alopecia areata onset through active counter-regulatory mechanism

96 the contribution from mild cases of alopecia areata [OR 1.48 (0.96, 2.29)], suggesting that IL-1 alph

97 between IL1-RN*1 allele and patchy alopecia areata (p =0.045).

98 cell-mediated disease mechanism in alopecia areata pathogenesis and suggested targeting antigen-pres

99 haired littermates transferred the alopecia areata phenotype.

100 In this paper, we analyzed alopecia areata probands in a family-based sample (n = 131 parent

101 ate possible mechanisms involved in alopecia areata resistance.

102 Because alopecia areata resistant mice showed unimpaired responsiveness a

103 In contrast, alopecia areata resistant mouse skin did not display increased nu

104 D44v variants, and FasL occurred in alopecia areata resistant mouse spleens.

105 ele was found to be associated with alopecia areata severity in a British case-control study.

106 d resistance locus) did not develop alopecia areata, supporting this locus as being important in alop

107 a, but high dietary soy oil reduces alopecia areata susceptibility.

108 effluvium (50.1 [33.9, 66.33]) and alopecia areata totalis/universalis (52.3 [23.1, 81.5]) were not

109 52), alopecia areata (n = 17), and alopecia areata totalis/universalis (n = 7).

110 ive lymphocytes may be effective in alopecia areata treatment.

111 of dermatological diseases such as alopecia areata, vitiligo, psoriasis and atopic dermatitis, commo

112 gate the role of the IL-1 system in alopecia areata we examined three biallelic polymorphisms within

113 pruritus, scabies, cellulitis, and alopecia areata were underrepresented in CDSR when matched with c

114 d mice with and without spontaneous alopecia areata, were similarly processed.

115 eata affected skin grafts developed alopecia areata, whereas 39 of 44 controls developed alopecia are

116 terized by loss of hair in patches (alopecia areata) with progression in some individuals to total lo