ライフサイエンスコーパス: arise

1 y heterogeneous, allowing shape diversity to arise.

2 experimental protein-based therapeutics can arise.

3 o understand how cancer stem cells (CSC) may arise.

4 ntrations, even before any clinical symptoms arise.

5 mechanism by which natural product diversity arises.

6 are successful, resistance to therapy often arises.

7 17) published concurrently with this Matters Arising.

8 ty of social media, important questions have arisen about the impact of online social interactions.

9 than previously suspected: at least 25 have arisen across three Drosophila species over the past 5.4

10 EBV+ PTLD can arise after primary EBV infection, or because of reactiv

11 alterations in cerebral energetic metabolism arise after traumatic brain injury (TBI).

12 ssociated changes, and cognitive dysfunction arising after sepsis recovery.

13 e2 in eukaryotes, palindromic amplifications arise and propagate in cells.

14 dynamical process that governs how mutations arise and spread through a population.

15 nts, to estimate how often plant feeding has arisen and to test whether this dietary transition is as

16 Little is known of how unique PNG mechanisms arose and evolved in eukaryotes.

17 of possibilities, new challenges expectedly arise, and our focus now must shift to determining the b

18 that the main ingredients for the effect to arise are the spatial phase separation of metallic and i

19 Double-hit lymphomas may arise as a consequence of the transformation of the unde

20 l size and its dependence on growth rate may arise as byproducts of a regulatory mechanism which evol

21 Differences in DNA methylation can arise as epialleles, which are loci that differ in chrom

22 Neoblast lineages arise as organogenesis begins and are required for const

23 cells correlates with melanoma invasion and arises as a result of intimate cell-cell contact.

24 rm drag, and the resistance to ice flow that arises as ice deforms to negotiate bed topography.

25 re directly examined by measuring the forces arising as an Atomic Force Microscope tip (diameter 20 n

26 dies in rats have indicated that arrhythmias arose as a result of augmentation of the late Na(+) curr

27 rceived opacity and translucency of surfaces arise at a level of representation where 3D shape is mad

28 (RPGR) cause retinal dystrophy, but how this arises at a molecular level is unclear.

29 y to common assumptions, this effect did not arise because of greater density or diversity of interac

30 es increased trophic efficiency, which could arise because of ocean warming and DSL shallowing.

31 If diseases in nature arise because of weaknesses in holobiont physiology, ins

32 survival bias and major neonatal morbidities arising before exposure to ligation.

33 alysis indicates that the S139N substitution arose before the 2013 outbreak in French Polynesia and h

34 ht-permeable materials and why discrepancies arise between the perception and physics of opacity and

35 whereby comparable estimates of C uptake can arise by invoking different sensitivities to key environ

36 nctions within a population, which typically arise by nonhomologous end joining.

37 His theories, however, did not arise de novo, being strongly influenced by Karl Kahlbau

38 relative levels of different ligands and can arise directly from competitive receptor-ligand interact

39 mental impact of producing the loaf of bread arises directly from wheat cultivation, with the use of

40 erstand how variation in protein levels that arise due to diabetes contribute to different VSMC behav

41 onal output and spatial representation could arise due to differences in computations performed by do

42 egation end products of fibrils are known to arise due to microstructural differences among the oligo

43 at photoconductance at resonant illumination arises due to the Coulomb interaction between the electr

44 Problems that arise during DNA replication can drive genomic alteratio

45 eral prefrontal cortex (DLPFC) and appear to arise during the protracted maturation of this circuitry

46 ax is a monocular cue to depth that commonly arises during observer translation.

47 Here we sequence spontaneously arising Emu-Myc lymphomas to define transgene architectu

48 We hypothesize that these discrepancies arise for metabolites far from the lower limit of the ma

49 ies, suggesting that nascent sex chromosomes arise frequently over the course of evolution.

50 s, we found that these memory-like phenomena arise from a confluence of rapid, short-lived positive s

51 Focal seizures are assumed to arise from a hypersynchronous activity affecting a circu

52 f pathological brain activity that appear to arise from a localised area of the brain.

53 Resistant cancer cells thus arise from a positive selection driven by BCL-XL modulat

54 Limitations of the study may arise from application of the rule by different clinicia

55 ms by which cognitive and motor dysfunctions arise from cerebellar degeneration.

56 luence and persuasion on receivers, in turn, arise from changes in the receiver's subjective valuatio

57 Retinoblastomas can arise from cone photoreceptor precursors in response to

58 since cortical dysfunction after stroke can arise from cortical damage or from white matter disconne

59 effects of pathogenic Htt on synaptic growth arise from defective synaptic endosomal trafficking, lea

60 These properties likely arise from different acetylation patterns, but determini

61 irections associated with Sb/In substitution arise from different atomic configurations for these ato

62 disparities in child development that might arise from differential investment in child health, nutr

63 rinciple simulations confirm that such bands arise from distinct acoustic phonons, connecting differe

64 e we suggest that perceptual suppression may arise from efficient sensorimotor computations, assuming

65 he density fluctuations behind the front can arise from either overcompensatory population growth or

66 forces are quantum mechanical in origin and arise from electrostatic interactions between fluctuatio

67 by strings, with topological properties that arise from embedding the strings in the interior of a 3D

68 15 A are at homo-oligomeric interfaces, 19% arise from family structural variation, and 27% are in r

69 MLCP activity may arise from functionally shared roles between MYPT1 and M

70 ns uncertain, as noncausal relationships may arise from genetic and environmental confounding (eg, pr

71 We show that signature 30 can arise from germline NTHL1 mutations.

72 elevated protein abundances did not directly arise from high tissue concentrations of Cl(-) or Na(+)

73 Individual differences in contact rate can arise from host, group and landscape heterogeneity and c

74 olds that neurodevelopmental brain disorders arise from imbalances in excitatory and inhibitory (E/I)

75 We propose that the higher-conducting states arise from in situ electrochemical conversion of the dat

76 ficial and/or deleterious effects ultimately arise from interactions at the cellular and subcellular

77 Theoretical models suggest that polarity can arise from localized feedbacks on Fat-Ds complexes at th

78 2017) shed light on how the jigsaw shape can arise from localized variations in wall stiffness betwee

79 increased study into cellular responses that arise from long-term or ectopic stimulation, especially

80 Boom-bust dynamics can arise from many causes, some closely associated with inv

81 is a common pregnancy complication that may arise from maternal, placental and/or fetal factors.

82 ut it is unknown whether these melanomas can arise from melanocyte stem cells (MCSCs).

83 Very few cancers, generally <0.5%, arise from mutations occurring solely in stem cells rath

84 acidity, and we could demonstrate that they arise from n-sigma* delocalization, not from an inductiv

85 e sclerosis, is clinically relevant, and may arise from one or more mechanisms that are at least part

86 ear that FUS is dosage-sensitive and effects arise from overexpression per se in transgenic strains.

87 While this variability is presumed to arise from overlapping synaptic input, its precise relat

88 trate that large numbers of chromaffin cells arise from peripheral glial stem cells, termed Schwann c

89 ural colors (SCs) of photonic crystals (PCs) arise from selective constructive interference of incide

90 ompositionally variant in the plant kingdom, arise from specialized fatty acid biosynthetic enzymes a

91 SPEM therefore did not arise from stem cells.

92 Mobility differences potentially arise from strain or surface effects originating from gr

93 Fundamentally, collective behavior must arise from the actions of individual cells.

94 d [5, 6], we propose that fibers generically arise from the aggregation of irregular particles with s

95 This limit is thought to arise from the brain's capacity to flexibly reconfigure

96 dition to potential confounding effects that arise from the comparison of structures in a crystal as

97 Since whole cell responses most often arise from the coordinated activity of multiple SCPs, we

98 Visuomotor mapping was found to arise from the dynamic interplay of three partly overlap

99 Fluctuations that arise from the generation and transport of mobility, fic

100 ric structures are to perturbations that may arise from the interplay between flexibility of the inte

101 Complex traits arise from the interplay between genetic and environment

102 tter antimicrobial stewardship are likely to arise from the introduction of diagnostic M. genitalium

103 ory cortex, which hitherto was considered to arise from the lateral pallium.

104 CCMs arise from the loss of an adaptor complex that negativel

105 e phenomena face fundamental challenges that arise from the multimodal nature of the interaction betw

106 by theoretical calculations, these plasmons arise from the nanometre-spaced confinement of extra oxy

107 ionality and technological applications that arise from their fascinating mechanical properties.

108 Two of these oscillations are shown to arise from three- and two-dimensional electronic bands,

109 Late I-waves are thought to arise from trans-synaptic cortical inputs and have a cru

110 alyses suggest that these repair differences arise from transiently forming loops and hairpins within

111 antigens, a class of HLA-bound peptides that arise from tumour-specific mutations.

112 These syndromes arise from unidentified environmental factors.

113 The remarkable hearing capacities of mammals arise from various evolutionary innovations.

114 in the literature concerning GpsB might have arisen from accumulation of unidentified suppressors, hi

115 f C2H4 along with CH4 at U less than -0.85 V arises from *CHO formation produced via an ER process of

116 This trait arises from a combination of factors including a denser

117 re we show that its population-wide activity arises from a low-dimensional spiral attractor.

118 t that for each nucleus the embryonic volume arises from a structural element contained within the vo

119 10-kD Class-2 PEPC hetero-octameric complex, arises from a tight interaction between 107-kD plant-typ

120 Endoplasmic reticulum (ER) stress arises from accumulation of misfolded/unfolded proteins

121 tial fraction of the twin-based heritability arises from common genetic variation.

122 lic acids indicates that the wall stiffening arises from cross-linkage to cell wall polymers.

123 d the possibility that the lymphopenia in WS arises from defects at the HSPC level.

124 reast cancer, compared with non-TNBC, likely arises from different pathogenetic pathways, and benign

125 Confusion arises from failure to distinguish between a genetically

126 Adopted immunity arises from four critical societal contributions to the

127 It is not known if adult LCH or ECD arises from hematopoietic stem cells (HSCs), nor which p

128 Thus, SCN circuit-level timekeeping arises from interdependent and mutually supportive astro

129 This arises from its capacity to form a complex with the modu

130 that the aggregation propensity of TRIOBP-1 arises from its central domain, with a short "linker" re

131 tune the exploitable electric behaviour that arises from motion of the imidazolium guest.

132 cannot meet that requirement, but the defect arises from neither increased GSC death nor premature di

133 echanisms by which neuroendocrine (NE) cells arises from prostate adenocarcinoma cells are poorly und

134 us in 70% of strains, and this heterogeneity arises from sequence exchange between strains as well as

135 tion to the well-established shear flow that arises from shearing between the reticular lamina and th

136 indicates that the formation of single SiNS arises from spontaneous delamination of nanosheets from

137 Quadrupolar splitting at the interface arises from strain based on lattice mismatch between the

138 structure competition is demonstrated, which arises from strain-induced spontaneous partitioning of P

139 demonstrate that this unexpected stimulation arises from Tg-induced conformational alterations and dy

140 This field dependence of inductance arises from the change of permeability, which correlates

141 The challenge arises from the existence of different competitive pathw

142 stic blue glow of Cerenkov luminescence (CL) arises from the interaction between a charged particle t

143 This limitation arises from the need for a soft, mechanically compliant

144 The novelty of this work arises from the new synthesis method for the core-shell

145 ter simulations indicate that this alignment arises from the preferential nucleation of prismatic cry

146 ing material with incident luminosity, which arises from the sublimation of dust; by the gravitationa

147 analysis of the oscillation suggests that it arises from the wavepacket motion on the ground state po

148 ers are completely differentiated from those arising from (13)C-labeled tracers, thereby allowing the

149 For each combination it is shown that ions arising from (2)H-labeled tracers are completely differe

150 try is a general feature of reversible gels, arising from a loss in entropy as chains transition to a

151 nerally considered a developmental disorder, arising from a mutation that disrupts the transcription

152 sal and pelagic flounders are a species pair arising from a recent event of speciation.

153 This study aimed to identify small peptides arising from actin proteolysis, as influenced by the typ

154 cripts detected fusion of the HPV/Myc genes, arising from apparent microhomologous recombination.

155 Third, reads potentially arising from background noise are filtered out to improv

156 differences in melting temperatures possibly arising from C-terminal conformational changes.

157 Tumors arising from centrosome amplification exhibit frequent m

158 large B-cell lymphoma (DLBCL; n = 34), DLBCL arising from chronic lymphocytic leukemia (Richter trans

159 emory function, with many beneficial actions arising from D1R stimulation.

160 e of trap states near the band edges of TiO2 arising from defects at grain boundaries significantly a

161 hat this death results from cell competition arising from differences in cellular differentiation sta

162 he notion that glucose metabolic impairments arising from disrupted NAc D2R signaling are involved in

163 o associated with hippocampal hyperactivity, arising from dysfunctional GABAergic interneurons.

164 Here we characterize the different lesions arising from each Cas9 variant and the resulting repair

165 ase stacking of pairs in dinucleotide steps, arising from energetically favorable stacking of the nit

166 n result in unintended off-target metabolism arising from enzyme promiscuity.

167 consequence of voluntary movement and those arising from events in the external world.

168 Aggregation of huntingtin protein arising from expanded polyglutamine (polyQ) sequences in

169 Therefore, the risks arising from exposure to silica and asbestos are well kn

170 rmal stability of photoluminescence emission arising from F8BT membrane lattices was thorough investi

171 suggest differential responses to selection arising from fluctuations in phylogenetic integration, t

172 sable for recognizing and eliminating danger arising from foreign invaders and tissue trauma.

173 and sequence data is obscured by uncertainty arising from four largely unobserved processes: transmis

174 we report that cGAS localizes to micronuclei arising from genome instability in a mouse model of mono

175 cNIC decreased baseline AMPA/NMDA ratio, arising from increased NMDA currents enriched in the NR2

176 he worsening of the amyloid plaque pathology arising from JIP3 haploinsufficiency in a mouse model of

177 ificant, increases in grain yield of 10-15%, arising from larger seed numbers and sizes.

178 as well as to changes in network parameters arising from learning-dependent synaptic plasticity.

179 Pathways arising from leg somatosensory neurons encode distinct q

180 nduced by the conformational entropy penalty arising from local perturbations of grafted and matrix c

181 Signals arising from measurement using multiple ion channels are

182 d spatial variability in PM10 concentrations arising from MWIs at postcodes (average 12 households) w

183 ricular nucleus with many synaptic afferents arising from neuromedin S(+) neurons of the suprachiasma

184 white-matter, discarding signals from it as arising from noise.

185 to severe replication-associated DNA damage arising from nucleolytic cleavage of stalled replication

186 filling this gap, SNc glutamatergic synapses arising from pedunculopotine nucleus (PPN) neurons were

187 mpositionally similar to terrestrial sources arising from permafrost thaw.

188 e can be used to uncover emergent properties arising from polypharmacological activity.

189 ting often fails to predict adverse outcomes arising from sequential, multi-organ metabolism of drugs

190 Multiple isomiRs and tRFs arising from specific miRNA loci (e.g., miR-200c, miR-21

191 In accordance with theory, the photons arising from spectral peaks that are suitably separated

192 Arising from spin-polarization transport, the as-obtaine

193 demonstrated that human SS and mouse tumors arising from SS18-SSX expression in the embryonic, but n

194 ion of backscattered radiation from "noise", arising from stochastic plasma fluctuations that compete

195 water forms transient microscopic "icebergs" arising from strengthened water hydrogen bonding, but th

196 often limited by high carrier recombination arising from strongly bound excitons and low carrier mob

197 as well as by enhanced recruitment of inputs arising from superficial layers to layer V.

198 Y chromophores along the edges of the cages, arising from the electronic delocalization through the m

199 also indicated by the eight-line EPR spectra arising from the I=7/2 (45) Sc nucleus.

200 so-called polydispersity effect (dispersion arising from the inevitable differences in migration vel

201 lications in the use of organic chromophores arising from the instability of their oxidized forms, th

202 We have measured the (75)As signals arising from the interface region of single-crystal semi

203 3 is a direct precursor to 4 or an artifact arising from the limited in vitro experiments.

204 mbled a light bulb filament (filament sign), arising from the peripheral iris (base of light bulb) an

205 We first group multiple features arising from the same analyte, which we call "degenerate

206 cal companies is subject not only to factors arising from their drug pipelines (idiosyncratic risk),

207 scillator device driven by pure spin current arising from thermal gradient across an Y3Fe5O12/Pt inte

208 Notably, tumors arising from these cell lines had higher versican levels

209 the lipid composition and dipolar relaxation arising from water penetration, but disentangling lipid

210 The gravitational-wave source GW170817 arose from a binary neutron-star merger in the nearby Un

211 s previously unclear whether face pareidolia arose from a uniquely human capacity.

212 esis that the second Vibrionaceae chromosome arose from an ancestral plasmid, and that RctB may have

213 based location of Iw2 We propose the Iw loci arose from an inverted duplication of W1-COE and/or W2-C

214 ds like pentanal and 6-methyl-5-hepten-2 one arose from blanching and boiling.

215 In melanoma that arose from DPN we find additional oncogenic alterations.

216 of acute febrile illness, Zika virus (ZIKAV) arose from obscurity when an Asian genotype ZIKAV caused

217 This question arose from our observation that most pediatric donors ca

218 e dorsal-ventral patterning function of Toll arose from the evolutionary cooption of a morphogen-resp

219 he expense of discrimination or vice versa - arose from the interaction of L6 CT neurons and subnetwo

220 stic evidence that this outbreak most likely arose from unvaccinated or under-vaccinated canines, not

221 EVP cells arose from vascular-resident beds that could not be tran

222 f WGD need not appear 'explosively', but can arise gradually over tens of millions of years, promotin

223 r, their work focused on the biases that can arise in ABMs that use parameters drawn from distinct po

224 culpting of the curved structures that often arise in accretive mineralization.

225 ns containing CD207(+)CD1a(+) cells that can arise in almost any tissue and cause significant morbidi

226 structure suggests how complex dynamics may arise in biological systems from elements whose combinat

227 rize networks and understand how communities arise in complex networks.

228 Such conditions arise in multicellular communities, where the formation

229 ence indicating that similar mutations could arise in naturally occurring bacterial populations facin

230 ns, such as addiction and schizophrenia, may arise in part from dysregulated activity of ventral tegm

231 te that bacterium-stimulated NET release may arise in part via NADPH oxidase-independent mechanisms.

232 ound by turning to social relationships that arise in religious institutions.

233 ons that specifically target adult-born DGCs arise in the epileptic brain, whereas axons of interneur

234 takeholders, over scientific trade-offs that arise in the field, to improvements scientists wish for.

235 lpha differs between endometrial tumors that arise in the presence or absence of tamoxifen, indicatin

236 Food-specific IgG antibodies arise in the setting of naturally resolving food allergy

237 ormation between BPs, where crystal features arise in the submicron regime, is found to be martensiti

238 Gamma oscillations arise in the subthalamic-globus pallidus feedback loop,

239 the distinctive quantum effects expected to arise in them.

240 emonstration of the quantitative issues that arise in transporting effects between populations has im

241 ther targeted therapies, resistance to PARPi arises in advanced disease.

242 How BTX autoresistance arises in such frogs remains a mystery.

243 Much of this functional diversity arises in the inner plexiform layer, where inhibitory am

244 sgenic zebrafish model of neuroblastoma that arises in the PSNS.

245 directionally selective and that selectivity arises in the T4 dendrites.

246 ermanent section margin control of melanomas arising in chronically sun-damaged skin on the head and

247 Streptococcus pneumoniae infections arising in hospitalized patients are often assumed to be

248 iew is to discuss the spectrum of CNS tumors arising in individuals with NF type 1 (NF1) and NF type

249 this is largely ineffective with resistance arising in most tumors following exposure to chemotherap

250 tests confirmed that many variants of [PSI+] arising in the absence of Siw14p are cured by restoring

251 edial prefrontal cortex (mPFC) pathways, one arising in the dorsal CA1 (dCA1) and the other in the in

252 hat the distribution of human rearrangements arising in the mouse was generally comparable to that se

253 The two major American oak clades arose in what is now the boreal zone and radiated, in pa

254 stral condition), the L-type arrangement has arisen independently several times during plant evolutio

255 Whether stomata arose once or whether they arose independently across newly evolving land plant lin

256 tiple subclones carrying different mutations arose independently, leading to subclonal heterogeneity

257 Reconstructing when this dichotomy arose is important for understanding when plate tectonic

258 n positron emission tomography signal, which arises largely from microglial activation, and measures

259 T2DM arises largely from obesity, poor diet, and lack of exer

260 ent with the hypothesis that PPhiB synthesis arose late in HY2 evolution.

261 it is not known whether evolutionary changes arise mainly after successful colonization has occurred,

262 disruption of either BRCA1 or BRCA2, and the arising mutation spectra showed strong and specific corr

263 BICs arise naturally from Feshbach's quantum mechanical theor

264 ive and superdiffusive/superballistic motion arises naturally as a result of the interplay between th

265 environmentally ubiquitous since life first arose nearly four billion years ago and presents a chall

266 ber enhanced Raman spectroscopy (FERS) is an arising new technique for versatile highly sensitive and

267 verse interpretations of Ediacaran organisms arise not only from their enigmatic body plans, but also

268 nderscore the importance of molecular noise, arising not only in gene expression but also in protein

269 uman hepatocellular carcinomas (HCCs), which arise on a background of chronic liver damage and inflam

270 Whether stomata arose once or whether they arose independently across ne

271 g pathway adaptations for speed, and if SFMs arose once, or from independent evolutionary events.

272 Poor clinical performance does not arise only from a lack of knowledge, a phenomenon known

273 re embolized, and substantial xylem embolism arose only under severe dehydration.

274 licensed in the United States (FluMist) have arisen over the past three seasons (2013-2014, 2014-2015

275 of curvature into the RSV CA hexamer lattice arises predominantly from reconfiguration of the NTD-CTD

276 of Chl reductions to increase photosynthesis arises primarily from the connection between Chl and lea

277 MP persistence arose secondary to binding of CFH to CD11b, which obstru

278 ngth (nSL) to detect beneficial alleles that arose since the settlement of the Andes and are currentl

279 Here, detailed analyses of spontaneously arising somatic mutations that recover CD247, and thus T

280 , prior to proliferation, is common in newly arising T cells (so-called "recent thymic emigrants") in

281 ity, a plethora of heuristic algorithms have arisen that report a 'good enough' solution to biologica

282 During cooling, toric focal conic domains arise through a sequence of morphological transformation

283 However, genomic islands can also arise through evolutionary processes unrelated to specia

284 Vs are considered random mutations but often arise through replication defects; transcription can int

285 phil recruitment, which we postulate instead arises through blunted up-regulation of CD147 expression

286 Antibody-resistant strains arising through further gene deletion could compromise s

287 assembly reveals that the unitary chromosome arose through fusion of six ancestral chromosomes, with

288 levels, Btn2p and Cur1p eliminate most newly arising [URE3] variants but do not cure [PSI(+)], even a

289 c pattern in the available ambient resources arose very early in the self-organization process and di

290 w genera of bacteria and is believed to have arisen via horizontal transfer.

291 Here, we describe potential biases that arise when ABM assumptions do not hold.

292 The gain arises when a saved seed is allocated to a node difficul

293 Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cel

294 ct signaling models to show that selectivity arises when inputs at successive locations are aligned w

295 A weakness with this approach arises when melting overhanging features, which have no

296 a similar but underappreciated threat, which arises when the geographic area (range) occupied by a sp

297 is caused by an amino acid polymorphism that arose when an ancestral threonine was mutated to alanine

298 The question thus arises whether there are instances where the quantum tim

299 We demonstrate how these naturally arise within a single p-orbital manifold as a general co

300 Broadly, because health arises within complex, dynamic, and hierarchical systems