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1 ion with Shaggy and two for interaction with Armadillo.
2 ough interactions with Drosophila Shaggy and Armadillo.
3 adherin does not accumulate with its partner Armadillo.
4 acts downstream of wingless and upstream of armadillo.
5 d by Axin, resulting in nuclear signaling by Armadillo.
6 ree genes: neuroglian (nrg), erect wing, and armadillo.
7 ssary for E-APC to function in destabilising Armadillo.
8 stabilization of beta-catenin and Drosophila Armadillo.
9 gmental patterning of the larval cuticle via Armadillo.
10 hort-term passage of strains in nude mice or armadillos.
11 was more common after long-term expansion in armadillos.
12 ation, the beta-catenin-related protein Worm armadillo 1 (WRM-1) also plays a role in controlling EMS
13 beta-catenin and its fruitfly counterpart Armadillo act as a coactivator in the canonical Wnt/Wing
14 we show that two gain-of-function alleles of Armadillo activate Wingless signaling by different mecha
15 covered a branch of the Wnt pathway in which Armadillo activity is regulated concomitantly with the l
16 ctors have been implicated in modulating TCF/Armadillo activity, their importance remains poorly unde
20 s signal causes stabilization of cytoplasmic Armadillo allowing it to enter the nucleus where it can
21 ion, can be mimicked by an activated form of armadillo and blocked by a dominant negative form of pan
22 n their own cause increased stabilization of Armadillo and cuticle pattern disruptions that include r
23 ed behind the furrow, and all cells show low Armadillo and DE-cadherin levels, although in the case o
24 ctin and ZO-1 in between, and a reduction of Armadillo and Discs lost within, mutant cells, indicativ
29 y transcriptional co-activators beta-catenin/Armadillo and TCF to facilitate context-dependent Wnt si
31 nome resequencing of M. leprae from one wild armadillo and three U.S. patients with leprosy revealed
32 ype (3I-2-v1) was found in 28 of the 33 wild armadillos and 25 of the 39 U.S. patients who resided in
37 such as Drosophila E-cadherin, beta-catenin/Armadillo, and alpha-spectrin, and the disruption of epi
40 oprecipitated with anti-DE-cadherin and anti-Armadillo antibodies from embryonic protein extracts.
41 that Akt regulates a complex containing Zw3, Armadillo, APC2, and EB1 and that this complex has a rol
45 l-autonomously, downstream or in parallel to Armadillo (Arm) and upstream of Wg-dependent target gene
46 and it regulates cell fate decisions through Armadillo (Arm) by acting as a receptor for the Wnt prot
49 hanisms of missense mutations located in the armadillo (ARM) domains of PKP2, as well as their conseq
56 tide can compete binding of the beta-catenin armadillo (arm) repeat domain to axin in vitro, indicati
57 protein contains both a U-box domain and an armadillo (ARM) repeat domain, which were demonstrated i
58 tional activation in vitro requires both the armadillo (ARM) repeats and the C terminus of beta-caten
59 tify a novel set of evolutionarily conserved Armadillo (ARM) repeats within CED-12/ELMO that mediate
61 he activity of the transcriptional activator Armadillo (Arm) to elicit precise, concentration-depende
64 rmines how efficiently Wnt signals stabilize Armadillo (Arm)/beta-catenin and activate downstream gen
68 We demonstrate that miR-310/13 can modulate Armadillo (Arm; Drosophila beta-catenin) expression and
69 developmental processes through a complex of Armadillo(Arm)/beta-catenin and the HMG-box transcriptio
70 lular accumulation of Actin, DE-cadherin and Armadillo associated with apical constriction of the cen
73 spatial distribution of organ blood flow in armadillos because they have genetically identical litte
74 GSK3beta, and CK1 that targets beta-catenin/Armadillo (beta-cat/Arm) for proteosomal degradation.
75 recycling endosomes (REs) and E-cadherin and Armadillo (beta-catenin) are both found in reduced amoun
77 is required for Cubitus interruptus (Ci) and Armadillo/beta-catenin (Arm) proteolysis, Roc1a mutant c
78 /E-cadherin (DE-cad) and its binding partner Armadillo/beta-catenin (beta-cat) are expressed in newly
81 enes that show greatest sequence homology to Armadillo/beta-catenin are called ARABIDILLO-1 and -2.
82 tivation of Armadillo/beta-catenin, and that Armadillo/beta-catenin does not play a general role in i
83 xpression of alphaPS integrin, inhibitors of Armadillo/beta-catenin nuclear activity and baculovirus
85 development by promoting the association of Armadillo/beta-catenin with TCFs on Wg-regulated enhance
86 ts of this adhesion process, DE-cadherin and Armadillo/beta-catenin, accumulate at high levels in the
87 certain cells are affected by activation of Armadillo/beta-catenin, and that Armadillo/beta-catenin
94 in-alpha-catenin fusion protein, which lacks Armadillo binding sites, causes similar defects as DE-ca
96 elevated levels of the beta-catenin homolog Armadillo but no alteration in Dsh abundance or distribu
99 todonts are in fact deeply nested within the armadillo crown-group, representing a distinct subfamily
101 ctures of complexes between the beta-catenin armadillo domain and the Lef-1 N-terminal domain show th
102 The crystal structure of the plakoglobin armadillo domain bound to phosphorylated E-cadherin show
103 addition, the expression of the beta-catenin armadillo domain disrupted the recruitment of beta-caten
106 We report that TbTOR4 associates with an Armadillo domain-containing protein (TbArmtor), a major
113 zed the genome sequence assemblies of human, armadillo, elephant, and opossum to identify informative
125 the Axin complex which earmarks beta-catenin/Armadillo for degradation by the proteasome pathway.
126 To test beta-catenin function, a truncated armadillo fragment was expressed in developing chicken s
127 , in M. leprae strains obtained from 33 wild armadillos from five southern states, 50 U.S. outpatient
128 pes obtained by different ways of activating Armadillo function and provides further support for the
129 h driver and responder controls, as follows: armadillo-GAL4 (up to 38%), Tubulin-GAL4 (up to 29%), C2
130 pendent loci with either a broad expression (armadillo-GAL4, Tubulin-GAL4, C23-GAL4, and da-GAL4) or
134 ith missense mutations in the LYST ARM/HEAT (armadillo/huntingtin, elongation factor 3, protein phosp
135 rews); (II) Xenarthra (sloths, anteaters and armadillos); (III) Glires (rodents and lagomorphs), as a
136 h releases cadherin-associated beta-catenin (Armadillo in Drosophila) and p120-catenin to induce rhom
142 an armadillo stabilization assay, increasing armadillo level at low concentrations but reducing it at
143 rmally required for controlling beta-catenin/Armadillo levels, suggesting that modulated degradation
145 ngated shape consisting of several irregular Armadillo-like repeats with two helical hairpins protrud
146 VHis a member of a gene family that contains Armadillo-like repeats, and NAPE-PLD encodes a phospholi
147 lpha-solenoid architecture constructed of 12 armadillo-like, tether-repeat, alpha-helical tripod moti
148 sults support the model where Axin regulates Armadillo localization and activity in the cytoplasm.
150 d Toll/IL-1R adaptor, sterile alpha and HEAT/Armadillo motif-containing protein (SARM), has remained
152 tenin is a neuronal protein that contains 10 Armadillo motifs and binds to the juxtamembrane segment
154 embryos secrete a lawn of ventral denticles; armadillo mutants also exhibit dorsal closure defects.
156 nts indicate that Pygopus acts downstream of Armadillo nuclear import, consistent with the nuclear lo
158 f 2 other Wnt signaling components, beta-cat/armadillo or TCF/pangolin, had relatively milder effects
164 We observed that p120 catenin (p120ctn), an Armadillo protein known to modulate cell motility, is co
166 t depend on cytodomain interactions with the armadillo protein plakoglobin or coexpression of its com
167 as 3 min; (2) the coalescence of DP and the armadillo protein plakophilin 2 into discrete cytoplasmi
169 provide evidence that loss of the desmosomal armadillo protein Plakophilin-2 (PKP2) in cardiomyocytes
172 espite these apparently paradoxical results, Armadillo protein, the transducer of Wnt signaling, does
177 In the flowering plant Arabidopsis thaliana, Armadillo-related ARABIDILLO proteins promote multicellu
178 s describe the characterization of PHOR1, an armadillo-related protein involved in gibberellin signal
181 served caspase consensus motif (DELD) within Armadillo repeat 6 of delta-catenin, was identified thro
182 e K(+) channel's alpha-subunit and the ninth armadillo repeat and carboxyl terminus of beta-catenin a
185 otein product of the BHD gene, and p0071, an armadillo repeat containing protein that localizes to th
187 s containing the Pkp-3 head domain and Pkp-1 armadillo repeat domain localized to the desmosome and t
188 Previous yeast 2-hybrid screens, using the armadillo repeat domain of APC as bait, identified hTID-
189 catenin-mediated transcription, bound to the armadillo repeat domain of beta-catenin, has been determ
190 ah-1 and TBL1 were found to bind to the same armadillo repeat domain of beta-catenin, suggesting that
192 he yeast two-hybrid system revealed that the armadillo repeat domain of p0071 bound directly to VE-ca
193 terminal "tails" that flank the beta-catenin armadillo repeat domain on ligand binding have also been
194 rystal structure of the importin-alpha3/MOS6 armadillo repeat domain suggests that five of the six Ar
195 go proteins interact with the importin-alpha armadillo repeat domain via nuclear localization sequenc
196 s containing the Pkp-1 head domain and Pkp-3 armadillo repeat domain were localized to the nucleus in
197 lation of beta-catenin by CK2 is the central armadillo repeat domain, where carrier proteins like axi
199 rminus of APC, involving both the heptad and armadillo repeat domains, whereas the APC binding site i
203 e addressed the requirement and functions of armadillo repeat gene deleted in velo-cardio-facial synd
204 hree-dimensional structure of a beta-catenin armadillo repeat in complex with the liver receptor homo
206 s a Thr653Lys substitution in the C-terminal armadillo repeat of beta-catenin and displayed a reduced
207 forms an alpha helix that binds to the first armadillo repeat of beta-catenin, which can be mutated t
208 mpetition experiments revealed that the 11th armadillo repeat of Vac8 is an important element for rec
213 ae, Vac8p, a myristoylated and palmitoylated armadillo repeat protein, is required for homotypic vacu
215 -specific binding protein, based on designed armadillo repeat proteins (dArmRP), binding to peptides
217 Plakoglobin and beta-catenin are homologous armadillo repeat proteins found in adherens junctions, w
219 chanical unfolding pathway, the beta-catenin armadillo repeat region (ARM) displays low mechanostabil
221 terminal beta-catenin "tails" that flank the armadillo repeat region reduces the affinity for desmoso
222 1) (PDZ) binding sites but lacks the central armadillo repeat region that binds cadherins and other p
223 ontaining protein (StBTB/POZ1) containing an Armadillo repeat region, was up-regulated in the mutant.
225 ystal structure of the PUL domain reveals an Armadillo repeat with high structural similarity to impo
227 abidopsis (Arabidopsis thaliana) plant U box/armadillo repeat-containing E3 ligase9 (AtPUB9), we iden
229 Here we describe the identification of the armadillo repeat-containing protein, ARMCX3, as a Sox10-
230 bling a protein kinase, termed STRAD, and an armadillo repeat-containing protein, named mouse protein
231 bling a protein kinase, termed STRAD, and an armadillo repeat-containing protein, named mouse protein
232 ins (Pkp-1, -2, and -3) comprise a family of armadillo repeat-containing proteins first identified as
234 a coli universal stress protein); At3g54870 (armadillo-repeat containing kinesin-related protein); At
235 ggest that Gudu and ARMC4 are a subfamily of Armadillo-repeat containing proteins that may have an ev
236 Here, we show that Arabidopsis thaliana ARMADILLO-REPEAT KINESIN1 (ARK1) plays a key role in roo
237 ghly homologous to vertebrate ARMC4, also an Armadillo-repeat-containing protein enriched in testes,
240 ic analysis reveals that PLSCR1 NLS binds to armadillo repeats 1-4 of importin alpha, but its interac
241 ICAT contains a 3-helix bundle that binds armadillo repeats 10-12 and a C-terminal tail that, simi
244 for the difference in signaling and that the Armadillo repeats account for the remainder of the diffe
246 8p may bind the fusion machinery through its armadillo repeats and that palmitoylation brings this ma
248 The direct binding required most of the armadillo repeats and was mutually exclusive for interac
249 ive LXXLL peptide motifs in the beta-catenin armadillo repeats did not disrupt either binding to andr
250 eats that bear unexpected resemblance to the armadillo repeats in beta-catenin and the HEAT repeats i
251 es the groove formed by the third and fourth armadillo repeats of beta-catenin and thus precludes the
253 e NH(2) terminus combined with the first six armadillo repeats of beta-catenin were shown to be neces
254 s PF16, an axonemal protein containing eight armadillo repeats predicted to be important for flagella
256 des approximately 200-kDa proteins with four Armadillo repeats similar to those in the nuclear pore p
257 encodes a large conserved protein with HEAT/Armadillo repeats that functions with sax-1, an NDR cell
258 eta-catenin physically interacts through its Armadillo repeats with the C-terminal transactivation do
259 from positions 133 to 363, which contains 4 armadillo repeats, and to the N-terminal adaptin-binding
261 eta-catenin, a family of proteins containing armadillo repeats, suggesting similar biological functio
262 We further demonstrate that the T. gondii armadillo repeats-only protein (TgARO) mutant, which is
274 7 counterpart in Drosophila, is required for Armadillo stabilization and plays a positive role in reg
275 erted a biphasic effect on Wg activity in an armadillo stabilization assay, increasing armadillo leve
276 These nuclear proteins are not required for Armadillo stabilization or the recruitment of TCF and Ar
278 Ewg and Ebd1 functionally interact with the Armadillo-TCF complex and mediate the same context-depen
279 ites, coupled with its ability to facilitate Armadillo-TCF interaction and transcriptional activity,
280 r the mammalian genomes of elephant, rabbit, armadillo, tenrec, platypus, pig, cat, bush baby, common
281 in a Wnt-dependent manner, where it augments Armadillo (the fly beta-catenin) transcriptional activat
283 hese findings, muscle-specific inhibition of Armadillo, the downstream transcriptional effector of th
284 hila have revealed that an activated form of Armadillo, the effector of Wnt signalling, interacts wit
285 Wg signaling causes nuclear translocation of Armadillo, the fly beta-catenin, which then complexes wi
286 t, PP1B, regulates stability of beta-Catenin/Armadillo: the outcome is to oppose T-cell factor (TCF)
288 atients and from M. leprae-infected mouse or armadillo tissues infected with 14 separate strains usin
291 n and Nito act redundantly downstream of TCF/Armadillo to activate many Wg transcriptional targets.
293 study investigated the role of sterile alpha/Armadillo/Toll-Interleukin receptor homology domain 1 pr
294 e Toll receptor adaptor Sarm1 (sterile alpha/Armadillo/Toll-Interleukin receptor homology domain prot
295 a Toll receptor adaptor dSarm (sterile alpha/Armadillo/Toll-Interleukin receptor homology domain prot
297 ests that a large portion of CFAP69 can form Armadillo-type alpha-helical repeats, which may mediate
298 cell walls of Mycobacterium leprae grown in armadillos was characterized and compared with that of M
299 In all cases, cells expressing activated Armadillo were able to migrate and extend cell processes
300 in horse and dog in contrast to elephant and armadillo, which showed high-centromeric sequence homoge
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